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Bazedoxifene acetate, also called as TSE424 or WAY-140424, is a selective nonsteroidal estrogen receptor modulator (SERM) with antiosteoporotic activity (ERα: IC50= 26 nM; ERβ= 99 nM). Uses: Bone density conservation agents. Synonyms: TSE 424; TSE-424; TSE424; WAY-140424; WAY 140424; WAY140424. Grades: 95%. CAS No. 198481-33-3. Molecular formula: C32H38N2O5. Mole weight: 530.66.
Bazedoxifene acetate
Bazedoxifene acetate (TSE-424 acetate) is an oral, nonsteroidal selective estrogen receptor modulator (SERM) , with IC 50 s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene acetate can be used for the research of osteoporosis. Bazedoxifene acetate also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TSE-424 acetate. CAS No. 198481-33-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0036.
Bazedoxifene acetate
Bazedoxifene, also known as WAY-140424, is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of their takeover of Wyeth Pharmaceuticals. In late 2013, Pfizer received approval for bazedoxifene as part of the combination drug DUAVEE in the prevention (not treatment) of postmenopausal osteoporosis. Bazedoxifene is an indole-based ER ligand that binds to both ERα (IC50 = 26 nM) and ERβ (IC50 = 99 nM). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Bazedoxifene acetate, WAY-140424; WAY140424; WAY 140424; TSE 424; TSE424; TSE-424; Viviant. Product Category: Others. Appearance: Solid powder. CAS No. 198481-33-3. Molecular formula: C32H38N2O5. Mole weight: 530.67. Purity: >96%. IUPACName: 1-(p-(2-(Hexahydro-1H-azepin-1-yl)ethoxy)benzyl)-2-(p-hydroxyphenyl)-3-methylindol-5-ol acetic acid. Canonical SMILES: OC1=CC2=C(C=C1)N(C(C3=CC=C(C=C3)O)=C2C)CC4=CC=C(C=C4)OCCN5CCCCCC5.CC(O)=O. Product ID: ACM198481333. Alfa Chemistry ISO 9001:2015 Certified.
Bazedoxifene Acetate
Bazedoxifene Acetate is a nonsteroidal selective estrogen receptor modulator (SERM). Bazedoxifene Acetate is used as an antiosteoporotic. Group: Biochemicals. Alternative Names: 1-[[4-[2- (Hexahydro-1H-azepin-1-yl) ethoxy]phenyl]methyl]-2- (4-hydroxyphenyl) -3-methyl-. Grades: Highly Purified. CAS No. 198481-33-3. Pack Sizes: 10mg. US Biological Life Sciences.
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Bazedoxifene (acetate)-B
Bazedoxifene (acetate)-B (TSE-424 (acetate)-B) is the B-crystal form compound of Bazedoxifene acetate (HY-A0036). Bazedoxifene acetate is an orally active, nonsteroidal selective estrogen receptor modulator (SERM), with IC 50 s of 23 nM and 99 nM for ERα and ERβ, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TSE-424 (acetate)-B. CAS No. 198481-33-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0036B.
Bazedoxifene (acetate)-D
Bazedoxifene (acetate)-D (TSE-424 (acetate)-D) is the D-crystal form compound of Bazedoxifene acetate (HY-A0036). Bazedoxifene acetate is an orally active, nonsteroidal selective estrogen receptor modulator (SERM), with IC 50 s of 23 nM and 99 nM for ERα and ERβ, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TSE-424 (acetate)-D. CAS No. 198481-33-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0036D.
1-(4-(Benzyloxy)-3-bromophenyl)-2-bromopropan-1-one is an impurity of 4'-(Benzyloxy)-2-bromopropiophenone (B285590), which is an intermediate of Bazedoxifene acetate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C16H14Br2O2, Molecular Weight: 398.09. US Biological Life Sciences.
1-(4-(Benzyloxy)-3-bromophenyl)-2-bromopropan-1-one-d7 is an isotope labelled impurity of 4'-(Benzyloxy)-2-bromopropiophenone (B285590), which is an intermediate of Bazedoxifene acetate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C16H7D7Br2O2, Molecular Weight: 405.13. US Biological Life Sciences.
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1-(4-(Benzyloxy)phenyl)-2-chloropropan-1-one
1-(4-(benzyloxy)phenyl)-2-chloropropan-1-one is an impurity of 4'-(Benzyloxy)-2-bromopropiophenone (B285590), which is an intermediate of Bazedoxifene acetate. Group: Biochemicals. Grades: Highly Purified. CAS No. 111000-54-5. Pack Sizes: 100mg, 250mg. Molecular Formula: C16H15ClO2, Molecular Weight: 274.74. US Biological Life Sciences.
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1-(4-(Benzyloxy)phenyl)-2-chloropropan-1-one-d5
1-(4-(benzyloxy)phenyl)-2-chloropropan-1-one-d5 is an isotope labelled impurity of 4'-(Benzyloxy)-2-bromopropiophenone (B285590), which is an intermediate of Bazedoxifene acetate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C16H10D5ClO2, Molecular Weight: 279.77. US Biological Life Sciences.
Worldwide
5-Methoxy-2-(p-methoxyphenyl)skatole
5-Methoxy-2-(p-methoxyphenyl)skatole is a reactant in the synthesis of a metabolite of Bazedoxifene (B129250), a nonsteroidal selective estrogen receptor modulator (SERM). Bazedoxifene Acetate is used as an antiosteoporotic. Group: Biochemicals. Grades: Highly Purified. CAS No. 91444-18-7. Pack Sizes: 50mg, 100mg. Molecular Formula: C17H17NO2. US Biological Life Sciences.
Worldwide
Des(1-azepanyl)ethyl Bazedoxifene
Des(1-azepanyl)ethyl Bazedoxifene is a metabolite of Bazedoxifene, a nonsteroidal selective estrogen receptor modulator (SERM). Bazedoxifene Acetate is used as an antiosteoporotic. Group: Biochemicals. Alternative Names: 2-(4-Hydroxyphenyl)-1-[(4-hydroxyphenyl)methyl]-3-methyl-1H-Indol-5-ol, 1-(4-Hydroxybenzyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol. Grades: Highly Purified. CAS No. 104599-10-2. Pack Sizes: 10mg. Molecular Formula: C22H19NO3. US Biological Life Sciences.
Worldwide
Propiophenone Impurity 2
An impurity of Propiophenone. 4'-(Benzyloxy)-2-bromopropiophenone is an intermediate of Bazedoxifene acetate.Bazedoxifene acetate is a third generation selective estrogen receptor modulator. Synonyms: 1-(4-(Benzyloxy)phenyl)-2-chloropropan-1-one; 2-Chloro-1-(4-phenylmethoxyphenyl)propan-1-one. Grades: > 95%. CAS No. 111000-54-5. Molecular formula: C16H15ClO2. Mole weight: 274.75.
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