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Benzo[a]pyrene. Group: Biochemicals. Alternative Names: Benzo[a]pyrene; 3,4-Benz[a]pyrene; 3,4-Benzopyrene. Grades: Highly Purified. CAS No. 50-32-8. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C20H12. US Biological Life Sciences.
Worldwide
Benzo[a]pyrene
Benzo[a]pyrene shows lung carcinogenicity in animal models, and it is frequently used in chemoprevention studies. Uses: Scientific research. Group: Natural products. Alternative Names: 3,4-Benzopyrene. CAS No. 50-32-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107377.
Benzo[a]pyrene (D12) 1 mg/mL in methylene chloride
Benzo[a]pyrene (D12) 1 mg/mL in methylene chloride. Uses: For analytical and research use. Group: Polycyclic aromatic hydrocarbons (pahs); stable isotope labelled compounds. Alternative Names: Benzo[a]pyrene D12,Benzo[a]pyrene-1,2,3,4,5,6,7,8,9,10,11,12-d12, Benzo[a]pyrene d12, Benzo[a]pyrene-d12 (9CI), Perdeuterated benzo[a]pyrene, [12-2H]Benzo[a]pyrene. CAS No. 63466-71-7. Pack Sizes: 1.2ML. IUPAC Name: 1,2,3,4,5,6,7,8,9,10,11,12-dodecadeuteriobenzo[a]pyrene. Molecular formula: C202H12. Mole weight: 264.38. Catalog: APS63466717D. SMILES: [2H]c1c([2H])c([2H])c2c(c1[2H])c([2H])c3c([2H])c([2H])c4c([2H])c([2H])c([2H])c5c([2H])c([2H])c2c3c45. Format: Single Solution. Shipping: Room Temperature.
Benzo[a]pyrene Diol Epoxide (BPDE)
Benzo[a]pyrene diol epoxide stimulates an inflammatory response in normal human lung fibroblasts through a p53 and JNK mediated pathway. Benzo [a]pyrene diol epoxide (BPDE), a carcinogen present in tobacco smoke as well as in environmental pollution, induces esophageal carcinogenesis. Group: Biochemicals. Alternative Names: (7R, 8S, 8aS, 9aR)-rel-7, 8, 8a, 9a-Tetrahydrobenzo[10, 11]chryseno[3, 4-b]oxirene-7, 8-diol; (7α,8 β, 8aα, 9aα)-7, 8, 8a, 9a-Tetrahydrobenzo[10, 11]chryseno[3, 4-b]oxirene-7, 8-diol; (±)-7α,8 β-Dihydroxy-9 β,10 β -epoxy-7, 8, 9, 10-tetrahydrobenzo [a]pyrene; (±)-7 β , 8α -Dihydroxy-9α , 10α -epoxy-7, 8, 9, 10-tetrahydrobenzo [a]pyrene; (±)-anti-BPDE; anti-Benzo[a]pyrene-7,8-diol-9,10-epoxide; trans-7, 8-Dihydroxy-anti-9, 10-epoxy-7, 8, 9, 10-tetrahydrobenzo [a]pyrene. Grades: Highly Purified. CAS No. 58917-67-2. Pack Sizes: 2.5mg. Molecular Formula: C??H??O?. US Biological Life Sciences.
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Benzo[a]pyrene (Standard)
Benzo[a]pyrene (Standard) is the analytical standard of Benzo[a]pyrene. This product is intended for research and analytical applications. Benzo[a]pyrene shows lung carcinogenicity in animal models, and it is frequently used in chemoprevention studies. Uses: Scientific research. Group: Natural products. CAS No. 50-32-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107377R.
6-Chlorobenzo[a]pyrene. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Manganese dilaurate, 6-Chlorobenzo(a)pyrene, 6-Chlorobenzeno(a)pyrene, BENZO(a)PYRENE, 6-CHLORO-, CID30546, BRN 2464084, LS-39941, 3-05-00-02520 (Beilstein Handbook Reference), 21248-01-1. Product Category: Heterocyclic Organic Compound. CAS No. 21248-01-1. Molecular formula: C20H11Cl. Mole weight: 286.754 g/mol. Purity: 0.96. IUPACName: 6-chlorobenzo[a]pyrene. Canonical SMILES: C1=CC=C2C(=C1)C3=C4C(=C2Cl)C=CC5=CC=CC(=C54)C=C3. Density: 1.378g/cm³. Product ID: ACM21248011. Alfa Chemistry ISO 9001:2015 Certified.
7,10-Dimethylbenzo[a]pyrene
7,10-Dimethylbenzo[a]pyrene. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7,10-dimethyl-benzo(a)pyren;7,10-DIMETHYLBENZO[A]PYRENE. Product Category: Heterocyclic Organic Compound. CAS No. 63104-33-6. Molecular formula: C22H16. Mole weight: 280.36. Product ID: ACM63104336. Alfa Chemistry ISO 9001:2015 Certified.
A metabolite of the environmental carcinogen benzo(a)pyrene, which is a benzopyrene-DNA adduct formed during subchronic dietary exposure to carcinogen benzo(a)pyrene (BaP). Synonyms: [7R-(7α, 8β, 9α, 10α)]-2'-Deoxy-N-(7, 8, 9, 10-tetrahydro-7, 8, 9-trihydroxybenzo[a]pyren-10-yl)-3'-guanylic Acid. Molecular formula: C36H43N6O10P. Mole weight: 750.73.
9,10-Dihydro-1-benzo[a]pyrene-7(8H)-one O-Acetyl Oxime. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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9,10-Dihydro-1-benzo[a]pyrene-7(8H)-one Oxime
9,10-Dihydro-1-benzo[a]pyrene-7(8H)-one Oxime. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
9,10-Dihydrobenzo[a]pyrene
9,10-Dihydrobenzo[a]pyrene is an environmental carcinogens oxidized by CYP2S1. Metabolized to Benzopyrene (B205800) by rat liver microsomes. Group: Biochemicals. Grades: Highly Purified. CAS No. 17573-15-8. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
9-Fluorobenzo[a]pyrene
9-Fluorobenzo[a]pyrene. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 9-fluorobenzo[a]pyrene, 9-Fluorobenzo(a)pyrene, BRN 1980311, BENZO(a)PYRENE, 9-FLUORO-, AG-G-78542, 71171-93-2, AC1L1AQY, Benzo[a]pyrene,9-fluoro-, CTK5D3608, LS-40022. Product Category: Heterocyclic Organic Compound. CAS No. 71171-93-2. Molecular formula: C20H11F. Mole weight: 270.3 g/mol. Purity: 0.96. IUPACName: 9-fluorobenzo[a]pyrene. Canonical SMILES: C1=CC2=C3C(=C1)C=CC4=C3C(=CC5=C4C=C(C=C5)F)C=C2. Density: 1.349g/cm³. Product ID: ACM71171932. Alfa Chemistry ISO 9001:2015 Certified.
9-Methylbenzo[a]pyrene
9-Methylbenzo[a]pyrene. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CCRIS 2442, 9-Methylbenzo(a)pyrene, BENZO(a)PYRENE, 9-METHYL-, BRN 2370818, 9-methylbenzo[a]pyrene, AC1L1AGS, LS-40041, 70644-19-8. Product Category: Heterocyclic Organic Compound. CAS No. 70644-19-8. Molecular formula: C21H14. Mole weight: 266.336 g/mol. Purity: 0.96. IUPACName: 9-methylbenzo[a]pyrene. Canonical SMILES: CC1=CC2=C(C=C1)C=C3C=CC4=C5C3=C2C=CC5=CC=C4. Density: 1.254g/cm³. Product ID: ACM70644198. Alfa Chemistry ISO 9001:2015 Certified.
Benzo[a] pyrene
Benzo[a] pyrene. CAS No: 50-32-8
Sarchem Laboratories New Jersey NJ
Benzopyrene Related Compound 11
A derivative of Benzopyrene. Benzopyrene is a carcinogenic component of tobacco smoke implicated in lung cancer. Synonyms: Benzo(a)pyrene 7,8-dihydrodiol; Benzo(a)pyrene-7,8-dihydrodiol; 7,8-dihydrobenzo[a]pyrene-7,8-diol; 7,8-Dihydrobenzo[pqr]tetraphene-7,8-diol; Benzo[a]pyrene-7,8-dihydrodiol; BP-7,8-dihydrodiol; 7,8-Diol-benzo(a)pyrene; Benzo(a)pyrene 7,8-diol; CCRIS 789; Benzo(a)pyrene-7,8-dihydrodiol, (E)-; 7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene; BENZO(a)PYRENE, 7,8-DIHYDRO-7,8-DIHYDROXY-, (E)-; BENZO(a)PYRENE, 7,8-DIHYDRO-7,8-DIHYDROXY-; SCHEMBL6735412; CHEBI:34562; DTXSID70928121; Q26840851. Grades: > 95%. CAS No. 13345-25-0. Molecular formula: C20H14O2. Mole weight: 286.33.
Benzopyrene Related Compound 12
A metabolite of Benzopyrene. Benzopyrene is a carcinogenic component of tobacco smoke implicated in lung cancer. Synonyms: 7,8-Benzo[a]pyrenequinone; 7,8-Dihydrobenzo[a]pyrene-7,8-dione; Benzo[a]pyrene-7,8-quinone. Grades: > 95%. CAS No. 65199-11-3. Molecular formula: C20H10O2. Mole weight: 282.3.
Benzopyrene Related Compound 1 (trans-Benzo[a]pyrene-4, 5-Dihydrodiol)
A derivative of Benzopyrene. Benzopyrene is a carcinogenic component of tobacco smoke implicated in lung cancer. Synonyms: (4R,5R)-rel-4,5-Dihydrobenzo[a]pyrene-4,5-diol; trans-4,5-Dihydrobenzo[a]pyrene-4,5-diol; (±)-Benzo[a]pyrene-trans-4,5-dihydrodiol; 4,5-Dihydrobenzo[a]pyrene-4,5-trans-(e,e)-diol; Benzo[a]pyrene-trans-4,5-dihydrodiol; trans-4,5-Dihydro-4,5-dihydroxybenzo[a]pyrene; trans-4,5-Dihydrodiolbenzo[a]pyrene; trans-4,5-Dihydroxy-4,5-dihydrobenzo[a]pyrene. Grades: > 95%. CAS No. 37571-88-3. Molecular formula: C20H14O2. Mole weight: 286.33.
Benzopyrene Related Compound 2 (Benzo[a]pyrene-6, 12-Quinone)
A metabolite of Benzopyrene. Benzopyrene is a carcinogenic component of tobacco smoke implicated in lung cancer. Synonyms: Benzo[a]pyrene-6,12-dione; 6,12-Dihydrobenzo[a]pyrene-6,12-dione; NSC 625589. Grades: > 95%. CAS No. 3067-12-7. Molecular formula: C20H10O2. Mole weight: 282.3.
Benzopyrene Related Compound 3 (Benzo[a]pyrene-7, 8-Diol)
A metabolite of Benzopyrene. Benzopyrene is a carcinogenic component of tobacco smoke implicated in lung cancer. Synonyms: 7,8-Dihydroxybenzo[a]pyrene. Grades: > 95%. CAS No. 57303-99-8. Molecular formula: C20H12O2. Mole weight: 284.32.
Benzopyrene Related Compound 4 (7-hydroxybenzo[a]pyrene)
A metabolite of Benzopyrene. Benzopyrene is a carcinogenic component of tobacco smoke implicated in lung cancer. Synonyms: 7-Hydroxybenzopyrene; Benzo[a]pyren-7-ol. Grades: > 95%. CAS No. 37994-82-4. Molecular formula: C20H12O. Mole weight: 268.32.
Benzopyrene Related Compound 5 (Benzo[a]pyrene 7, 8-Oxide)
A metabolite of Benzopyrene. Benzopyrene is a carcinogenic component of tobacco smoke implicated in lung cancer. Synonyms: 6b,7a-Dihydro-benzo[10,11]chryseno[1,2-b]oxirene; (±)-6b,7a-Dihydro-benzo[10,11]chryseno[1,2-b]oxirene; Benzo[a]pyrene 7,8-Epoxide. Grades: > 95%. CAS No. 36504-65-1. Molecular formula: C20H12O. Mole weight: 268.32.
Benzopyrene Related Compound 7 (Benzo[a]pyrene-3, 6- Quinone)
A metabolite of Benzopyrene. Benzopyrene is a carcinogenic component of tobacco smoke implicated in lung cancer. Synonyms: 9,10-Dihydroxybenzo[a]pyrene; Benzo[a]?pyrene-9,?10-diol. Grades: > 95%. CAS No. 57303-98-7. Molecular formula: C20H12O2. Mole weight: 284.32.
Dibenzo[a,i]pyrene
Dibenzo[a,i]pyrene is a polycyclic aromatic hydrocarbon (PAH) with potent carcinogenic activity. Dibenzo[a,i]pyrene was shown to induce DNA adduction, tumorigenicity as well as Ki-ras oncogene mutations in strain A/J mouse lung. Dibenzo[a,i]pyrene has been shown to be present in cigarette smoke condensate and in automobile exhaust gas in small quantities. Group: Biochemicals. Alternative Names: Benzo[rst]pentaphene; Benzo[rst]pentacene; 1,2:7,8-Dibenzpyrene; 3,4:9,10-Dibenzopyrene; Dibenzo[b,h]pyrene; NSC 87521. Grades: Highly Purified. CAS No. 189-55-9. Pack Sizes: 10mg. US Biological Life Sciences.
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Dibenzo[a,i]pyrene[5,8]quinone
Dibenzo[a,i]pyrene[5,8]quinone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DIBENZO[A,I]PYRENE[5,8]QUINONE;benzo(r,s,t)pentaphene-5,8-dione. Product Category: Heterocyclic Organic Compound. CAS No. 3302-52-1. Molecular formula: C24H12O2. Mole weight: 332.35. Product ID: ACM3302521. Alfa Chemistry ISO 9001:2015 Certified.
Used in the preparation of carcinogenic Benzo[a]pyrene Diol Epoxide (B287550). Group: Biochemicals. Grades: Highly Purified. CAS No. 57405-00-2. Pack Sizes: 10mg. US Biological Life Sciences.
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trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene.
trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene is a metabolite of Benzopyrene (B205800). Benzo[a]pyrene (B205800), a prototypic PAH, is metabolized by cytochrome P 450 1A1/1B1. (-)-trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene (D452280) undergoes further P 4501A1/1B1-mediated metabolism to a carcinogen, which forms DNA-adducts primarily with 2'-deoxyguanosine. A carcinogen. Group: Biochemicals. Alternative Names: (±)-trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene; Benzo[a]pyrene-trans-7,8-dihydrodiol; trans-7, 8-Dihydro-7, 8-dihydroxybenzo [a]pyrene; trans-7,8-Dihydrobenzo[a]pyrene-7,8-diol; trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene; trans-Benzo[a]pyrene-7,8-dihydrodiol. Grades: Highly Purified. CAS No. 57404-88-3. Pack Sizes: 2.5mg. US Biological Life Sciences.
Protected trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene (D452280), a metabolite of Benzopyrene (B205800). A carcinogen. Group: Biochemicals. Alternative Names: (7R,8R)-rel-7,8-Dihydro-benzo[a]pyrene-7,8-diol 7,8-Dibenzoate. Grades: Highly Purified. CAS No. 57405-08-0. Pack Sizes: 5mg. US Biological Life Sciences.
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1,11,12,12a-Tetrahydro-benzopyren-3-one
Benzopyrene derivative. Group: Biochemicals. Alternative Names: 1,11,12,12a-Tetrahydro-benzo[a]pyren-3(2H)-one. Grades: Highly Purified. CAS No. 853925-19-6. Pack Sizes: 1mg. US Biological Life Sciences.
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1-Ethenylpyrene
1-Ethenylpyrene (1-Vinylpyrene) is an anti-chemical carcinogen that inhibits the formation of skin tumors initiated by either DMBA (HY-W011845) or Benzo[a]pyrene (HY-107377) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1-Vinylpyrene. CAS No. 17088-21-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W543743.
2-[ (1, 2, 3, 6, 7, 8-Hexahydro-4-pyrenyl) carbonyl]benzoic Acid is an intermediate in the synthesis of Naphtho[2,3-e]pyrene (H294710), which is a polycyclic aomatic hydrocarbon (PAH) with carcinogenicity. Naphtho[2,3-e]pyrene is one of the C24H14 PAH that displayed mutagenicity in human cells expressing CYP1A1. Group: Biochemicals. Grades: Highly Purified. CAS No. 855470-22-3. Pack Sizes: 25mg, 50mg. Molecular Formula: C24H20O3. US Biological Life Sciences.
2-[2,6-Bis(2-methoxyethenyl)phenyl]-7-methoxynaphthalene is an metabolite of Benzo[a]pyrene, a carcinogenic component of tobacco smoke implicated in lung cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 1094898-04-0. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C23H22O3. US Biological Life Sciences.
2- (7-Methoxy-2-naphthalenyl) -1, 3- Benzene dicarboxaldehyde is an metabolite of Benzo[a]pyrene, a carcinogenic component of tobacco smoke implicated in lung cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 1094898-02-8. Pack Sizes: 10mg , 25mg. Molecular Formula: C19H14O3. US Biological Life Sciences.
2-(7-Methoxy-2-naphthalenyl)-5,5-dimethyl-1,3,2-dioxaborinane is an intermediate in the synthesis of metabolites of Benzo[a]pyrene, a carcinogenic component of tobacco smoke implicated in lung cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 1094897-81-0. Pack Sizes: 10mg, 25mg. Molecular Formula: C16H19BO3. US Biological Life Sciences.
Worldwide
3-Hydroxy Benzopyrene
A metabolite of Benzopyrene (BaP), a carcinogenic component of tobacco smoke implicated in lung cancer. Group: Biochemicals. Alternative Names: Benzo[a]pyren-3-ol. Grades: Highly Purified. CAS No. 13345-21-6. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
3-Hydroxy Benzopyrene
A metabolite of Benzopyrene.Benzopyrene is a carcinogenic component of tobacco smoke implicated in lung cancer. Synonyms: Benzo[a]pyren-3-ol; 3-Hydroxy-3,4-benzo[a]pyrene; 3-Hydroxybenzo[a]pyrene. Grades: > 95%. CAS No. 13345-21-6. Molecular formula: C20H12O. Mole weight: 268.32.
3-Hydroxy Benzopyrene-d11
A labeled metabolite of Benzopyrene (BaP), a carcinogenic component of tobacco smoke implicated in lung cancer. Group: Biochemicals. Alternative Names: Benzo[a]pyren-3-ol. Grades: Highly Purified. CAS No. 1246819-35-1. Pack Sizes: 500ug. US Biological Life Sciences.
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3-Methoxy Benzopyrene
Metabolite of 3,4-Benzopyrene. Carcinogenic. Group: Biochemicals. Alternative Names: 3-Methoxy Benzo[a]pyrene. Grades: Highly Purified. CAS No. 63059-68-7. Pack Sizes: 1mg. US Biological Life Sciences.
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7,8,9,10-Tetrahydro-benzo[a]pyren-7-ol
7,8,9,10-Tetrahydro-benzo[a]pyren-7-ol is a Benzopyrene (B205800) derivative, activated by hepatic cytosol. Group: Biochemicals. Alternative Names: (RS) -7, 8, 9, 10-Tetrahydrobenzo [a]pyren-7-ol; (±) -7, 8, 9, 10-Tetrahydrobenzo [a]pyren-7-ol; 7-Hydroxy-7, 8, 9, 10-tetrahydrobenzo [a]pyrene; NSC 30871. Grades: Highly Purified. CAS No. 6272-55-5. Pack Sizes: 100mg. US Biological Life Sciences.
9-Hydroxy benzopyrene. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 9-Hydroxybenzo(a)pyrene. Product Category: Heterocyclic Organic Compound. CAS No. 17573-21-6. Molecular formula: C20H12O. Mole weight: 268.3. Product ID: ACM17573216. Alfa Chemistry ISO 9001:2015 Certified.
9-Hydroxy Benzopyrene
A metabolite of Benzopyrene.Benzopyrene is a carcinogenic component of tobacco smoke implicated in lung cancer. Synonyms: Benzo[a]pyren-9-ol; 9-Hydroxybenzo[a]pyrene. Grades: > 95%. CAS No. 17573-21-6. Molecular formula: C20H12O. Mole weight: 268.32.
Benz[j]aceanthrylene-13C2,d2 and Benz[e]aceanthrylene-13C2,d2
Labeled Benz[j]aceanthrylene. Polycyclic aromatic hydrocarbons (PAHs) and their PAH-DNA adducts in lung tissues, and their ability to mutate the Ki-ras oncogene in PAH-induced tumors. Seven PAHs were studied: cyclopenta[cd]pyrene (CPP), benzo[a]pyrene (B[a]P), benzo[b]fluoranthene (B[b]F), dibenz[a,h]anthracene (DBA), 5-methylchrysene (5MC), benz[j]aceanthrylene (B[j]A), and dibenzo[a,l]pyrene (DB[a,l]P). Group: Biochemicals. Alternative Names: Benz[7,8]aceanthrylene-13C2,d2 and Benz[4,5]aceanthrylene-13C2,d2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Benz[j]aceanthrylene and Benz[e]aceanthrylene (70:30 Mixture)
Polycyclic aromatic hydrocarbons (PAHs) and their PAH-DNA adducts in lung tissues, and their ability to mutate the Ki-ras oncogene in PAH-induced tumors. Seven PAHs were studied: cyclopenta[cd]pyrene (CPP), benzo[a]pyrene (B[a]P), benzo[b]fluoranthene (B[b]F), dibenz[a,h]anthracene (DBA), 5-methylchrysene (5MC), benz[j]aceanthrylene (B[j]A), and dibenzo[a,l]pyrene (DB[a,l]P). Group: Biochemicals. Alternative Names: Benz[7,8]aceanthrylene and Benz[4, 5]aceanthrylene. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Benzo [e] pyrene
Benzo [e] pyrene. CAS No: 192-97-2
Sarchem Laboratories New Jersey NJ
Benzo(l m N)phenanthridine
Benzo(l m N)phenanthridine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: benzo(l m n)phenanthridine;4-Azapyrene;Thebenidine;Brn 0138610;Ccris 1604;Dibenzo(C,D,E)quinoline;Einecs 205-894-8;Pyrenidine. Product Category: Heterocyclic Organic Compound. CAS No. 194-03-6. Molecular formula: C15H9N. Product ID: ACM194036. Alfa Chemistry ISO 9001:2015 Certified.
Benzopyrene
Benzopyrene is a polyaromatic hydrocarbon (PAH) found in coal tar. Benzopyrene is a known carcinogen. The metbolism of Benzopyrene results in diol epoxides that react and bind to DNA forming adducts which in turns leads to mutations and eventually cancer. Group: Biochemicals. Alternative Names: Benzo[a]pyrene; 3,4-Benz[a]pyrene; 3,4-Benzopyrene; 3,4-Benzpyrene; 4,5-Benzpyrene; 6,7-Benzopyrene; BaP; Benz[a]pyrene; Benzo[d,e,f]chrysene; Benzopyrene; NSC 21914. Grades: Highly Purified. CAS No. 50-32-8. Pack Sizes: 100mg. US Biological Life Sciences.
Benzothioxanthene dicarboxylic anhydride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4,10-benzothioxanthene-3,1-dicarboxylic acid anhydride; benzothioxanthenedicarboxylic acid anhydride; benzo[kl]thioxanthene-3,4-dicarboxylic acid anhydride; 1h,3h-thioxantheno[2,1,9-def]-2-benzopyran-1,3-dione; benzothioxanthene-3,4-dicarboxylic anhydride; thioxantheno[2,1,9-def]isochromene-1,3-dione; BENZOTHIOANTHENEDICARBOXYLICANHYDRIDE; 1H,3H-2-Oxa-6-thiabenzo[a]pyrene-1,3-dione; thioxantheno[2,1,9-dej]isochromene-1,3-dione. CAS No. 14121-49-4. Molecular formula: H18H8O3S. Mole weight: 304.3. Purity: 0.97. IUPACName: Benzothioxanthene dicarboxylic anhydride. Canonical SMILES: C1=CC=C2C(=C1)C3=C4C(=CC=C5C4=C(C=C3)C(=O)OC5=O)S2. Density: 1.56g/cm³. Product ID: ACM14121494. Alfa Chemistry ISO 9001:2015 Certified.
Biochanin A (5,7-Dihydroxy-4-methoxyisoflavone)
An isoflavone with anticancer proliferation, differentiation and chemopreventitive properties. Inhibits metabolic activation of benzo[a]pyrene. Group: Biochemicals. Alternative Names: 5,7-Dihydroxy-4-methoxyisoflavone. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
(-)-cis-anti-N2-BPDE-dG
(-)-cis-anti-N2-BPDE-dG is used in the study of carcinogen-DNA adducts and their role in affecting eukaryotic DNA methyltransferases. Cluster-type DNA damage is often seen in DNA and is usually skipped by base excision repair. Synonyms: [7S-(7α,8β,9β,10β)]-2'-Deoxy-N-(7,8,9,10-tetrahydro-7,8,9-trihydroxybenzo[a]pyren-10-yl)guanosine; Benzo[a]pyrene Guanosine deriv.; (-)-cis-anti-7,8,9-Trihydroxy-10-(2'-deoxyguanosin-2-yl)benzo[a]pyrene. CAS No. 66113-73-3. Molecular formula: C30H27N5O7. Mole weight: 569.56.
(+)-cis-anti-N2-BPDE-dG
(+)-cis-anti-N2-BPDE-dG is used in the study of carcinogen-DNA adducts and their role in affecting eukaryotic DNA methyltransferases. Cluster-type DNA damage is often seen in DNA and is usually skipped by base excision repair. Synonyms: [7R-(7α,8β,9β,10β)]-2'-Deoxy-N-(7,8,9,10-tetrahydro-7,8,9-trihydroxybenzo[a]pyren-10-yl)-Guanosine; Benzo[a]pyrene, guanosine deriv.; (+)-cis-anti-7,8,9-Trihydroxy-10-(2'-deoxyguanosin-2-yl)benzo[a]pyrene. CAS No. 66141-82-0. Molecular formula: C30H27N5O7. Mole weight: 569.56.
Heliomycin
It is produced by the strain of Actinomyces flavochromogenes var. heliomycini. It is a quinone antibiotic. It can inhibit RNA formation, has strong anti-gram-positive bacterial activity, and has vasoconstriction effect. It is used to treat burns and pyoderma and can also be added to cosmetics. Synonyms: Geliomycin; Croceomycin; Heliomycin; Itamycin; Antibiotic A 3733A; 2H-Benzo(cd)pyrene-2,6(1H)-dione,3,5,7,10-tetrahydroxy-1,1,9-trimethyl-. Grades: >95% by HPLC. CAS No. 11029-70-2. Molecular formula: C22H16O6. Mole weight: 376.36.
microsomal epoxide hydrolase
This is a key hepatic enzyme that is involved in the metabolism of numerous xenobiotics, such as 1,3-butadiene oxide, styrene oxide and the polycyclic aromatic hydrocarbon benzo[a]pyrene 4,5-oxide. In a series of oxiranes with a lipophilic substituent of sufficient size (styrene oxides), monosubstituted as well as 1,1- and cis-1,2-disubstituted oxiranes serve as substrates or inhibitors of the enzyme. However, trans-1,2-disubstituted, tri-and tetra-substituted oxiranes are not substrates. The reaction involves the formation of an hydroxyalkyl-enzyme intermediate. In vertebrates, five epoxide-hydrolase enzymes have been identified to date: EC 3.3.2.6 (leukotriene-A4 hydrolase), ...hydratase (ambiguous); benzo[a]pyrene-4,5-oxide hydratase; benzo(a)pyrene-4,5-epoxide hydratase; aryl epoxide hydrase (ambiguous); cis-epoxide hydrolase; mEH. Enzyme Commission Number: EC 3.3.2.9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4006; microsomal epoxide hydrolase; EC 3.3.2.9; epoxide hydratase (ambiguous); microsomal epoxide hydratase (ambiguous); epoxide hydrase; microsomal epoxide hydrase; arene-oxide hydratase (ambiguous); benzo[a]pyrene-4,5-oxide hydratase; benzo(a)pyrene-4,5-epoxide hydratase; aryl epoxide hydrase (ambiguous); cis-epoxide hydrolase; mEH. Cat No: EXWM-4006.
Native Rhodococcus rhodochrous Epoxide Hydrolase
Epoxide hydrolase (also known as epoxide hydratase) functions in detoxification during drug metabolism. It converts epoxides to trans-dihydrodiols, which can be conjugated and excreted from the body. Epoxides result from the degradation of aromatic compounds. Deficiency in this enzyme in patients receiving aromatic-type anti-epileptic drugs such as phenytoin is reported to lead to DRESS syndrome. Epoxides are significant as cytochrome P450 oxidase metabolites of unsaturated carbon-carbon bonds, but are also mutagenic. Epoxide hydrolase is present in large quantity on endoplasmic reticulum. Group: Enzymes. Synonyms: EC 3.3.2.3; epoxide hydratase; epoxide hydratase (ambiguous); microsomal epoxide hydratase; epoxide hydrase; microsomal epoxide hydrase; arene-oxide hydratase (ambiguous); benzo[a]pyrene-4,5-oxide hydratase; benzo (a)pyrene-. Enzyme Commission Number: EC 3.3.2.3. CAS No. 9048-63-9. mEH. Activity: > 0.5 U/g. Storage: -20°C. Form: lyophilized powder, beige. Source: Rhodococcus rhodochrous. EC 3.3.2.3; epoxide hydratase; epoxide hydratase (ambiguous); microsomal epoxide hydratase; epoxide hydrase; microsomal epoxide hydrase; arene-oxide hydratase (ambiguous); benzo[a]pyrene-4,5-oxide hydratase; benzo (a)pyrene-4,5-epoxide hydratase; aryl epoxide hydrase (ambiguous); cis-epoxide hydrolase; mEH; 9048-63-9. Cat No: NATE-0449.
Pyrene
Pyrene is a colorless solid, solid and solutions have a slight blue fluorescence. Used in biochemical research. (EPA, 1998);Liquid;Solid;PALE YELLOW OR COLOURLESS SOLID IN VARIOUS FORMS.;Colorless solid, solid and solutions have a slight blue fluorescence. Group: Carbon nano materials electroluminescence materials other electronic materials sublimed materials other materials. Alternative Names: Benzo[def]phenanthrene. CAS No. 129-00-0. Product ID: pyrene. Molecular formula: 202.25. Mole weight: C16H10. C1=CC2=C3C(=C1)C=CC4=CC=CC(=C43)C=C2. InChI=1S / C16H10 / c1-3-11-7-9-13-5-2-6-14-10-8-12 (4-1) 15 (11) 16 (13) 14 / h1-10H. BBEAQIROQSPTKN-UHFFFAOYSA-N.
Pyrene
Pyrene is a polycyclic aromatic hydrocarbon (PAH) composed of four fused benzene rings. It has a distinct aromatic odor, produced by incomplete combustion of organic matter. Pyrene exhibits strong fluorescence, emitting in the blue region of the spectrum, making it useful as a probe for studying molecular interactions in solution and on surfaces. Pyrene is also used as a model compound for the study of PAHs in various environments and biological systems because of its ubiquity in these environments. However, long-term exposure to pyrene has been associated with potential health risks, including carcinogenicity and mutagenicity. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Benzo[def]phenanthrene. CAS No. 129-00-0. Pack Sizes: 10 g; 25 g. Product ID: HY-103609.
Pyrene
Pyrene occurs in coal tar. Also obtained by the destructive hydrogenation of hard coal. Found in wastewater in aquatic environments, and possesses genotoxic characteristics relating to estrogenic/androgenic, antiestrogenic and antiandrogenic activity. Group: Biochemicals. Alternative Names: Benzo [def]phenanthrene; NSC 17534; NSC 66449. Grades: Highly Purified. CAS No. 129-00-0. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
Resistoflavine
A rare, boat-shaped, pentacyclic polyketide isolated from several species of streptomyces; exhibits weak antibacterial activity against gram-positive and gram-negative bacteria; exhibits potent cytotoxic activity against tumour cell lines in vitro; inhibits growth, and nucleic acid and protein synthesis in bacillus subtilis. Synonyms: Resistoflavin; BRN 2491848; (-)-3,5,7,11b-Tetrahydroxy-1,1,9-trimethyl-2H-benzo(cd)pyrene-2,6,10(1H,11bH)-trione. Grades: >98% by HPLC. CAS No. 29706-96-5. Molecular formula: C22H16O7. Mole weight: 392.36.
(+)-trans-anti-BPDE-N2-dG
(+)-trans-anti-BPDE-N2-dG is used in the study of carcinogen-DNA adducts and their role in affecting eukaryotic DNA methyltransferases. Cluster-type DNA damage is often seen in DNA and is usually skipped by base excision repair. Also, as a common concern due to tobacco smoke, this compound used to obtain a better understanding of the effects of carcinnogen-DNA adducts. Synonyms: (+)-trans-anti-Benzo[a]pyrene-dG; 10S(+)-trans-anti-[Py]-N2-dG; [7R-(7α, 8β, 9β, 10α)]-2'-deoxy-N-(7, 8, 9, 10-tetrahydro-7, 8, 9-trihydroxybenzo[a]pyren-10-yl)guanosine; Benzo[a]pyrene, guanosine deriv.; (+)-r-7,t-8-Dihydroxy-t-9,10-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene-dG; (+)-trans-anti-7,8,9-Trihydroxy-10-(2'-deoxyguanosin-2-yl)benzo[a]pyrene. CAS No. 65437-20-9. Molecular formula: C30H27N5O7. Mole weight: 569.56.
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