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N-(m-PEG4)-3,3-Dimethyl-3H-indole-N'-(acid-PEG3)-Benzothiazole Cy5 is a PEG linker containing a cyanine dye with excitation/emmission maximum 649/667 nm and a free terminal carboxyl acid. Terminal carboxylicacid can react with primary amine groups in the presence of of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydophilic PEG spacer increases solubility in aqueous media. Uses: For industrial and laboratory use. Group: Cyanine dyes. CAS No. 2107273-86-7. Molecular formula: C40H55ClN2O9S. Mole weight: 775.4 g/mol. Purity: 0.98. Catalog: DYE-FLU-0014.
N-(m-PEG4)-N'-(acid-PEG3)-Benzothiazole Cy5
N-(m-PEG4)-N'-(acid-PEG3)-Benzothiazole Cy5 is a PEG linker containing a cyanine dye with excitation/emmission maximum 649/667 nm and a free terminal carboxyl acid. Terminal carboxylicacid can react with primary amine groups in the presence of of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydophilic PEG spacer increases solubility in aqueous media. Uses: For industrial and laboratory use. Group: Cyanine dyes. CAS No. 2107273-80-1. Molecular formula: C37H49ClN2O9S2. Mole weight: 765.4 g/mol. Purity: 0.98. Catalog: DYE-FLU-0013.
N,N'-bis-(acid-PEG3)-Benzothiazole Cy5
N,N'-bis-(acid-PEG3)-Benzothiazole Cy5 is a PEG linker containing a cyanine dye with excitation/emmission maximum 649/667 nm and a free terminal carboxyl acid. Terminal carboxylicacid can react with primary amine groups in the presence of of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydophilic PEG spacer increases solubility in aqueous media. Uses: For industrial and laboratory use. Group: Cyanine dyes. CAS No. 2107273-82-3. Molecular formula: C37H47ClN2O10S2. Mole weight: 779.4 g/mol. Purity: 0.98. Catalog: DYE-FLU-0018.
Tropifexor
Tropifexor is a novel highly potent agonist of farnesoid X receptor (FXR), which regulates bile acid metabolism and signaling. FXR activated by Tropifexor can inhibit bile acid synthesis as well as increase bile acid conjugation, transport and excretion. Tropifexor entered phase II clinical trials for the treatment of NASH and PBC. Synonyms: Tropifexor; LJN452; LJN-452; LJN 452;; 2-[(1R,5S)-3-[[5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl]methoxy]-8-azabicyclo[3.2.1]octan-8-yl]-4-fluoro-1,3-benzothiazole-6-carboxylicacid. Grades: ≥98%. CAS No. 1383816-29-2. Molecular formula: C29H25F4N3O5S. Mole weight: 603.589.
2-Amino-α-oxo-4-thiazoleethanethioic Acid S-2-Benzothiazolyl Ester is an intermediate in synthesizing (6R,7R)-7-(2-(2-Aminothiazol-4-yl)-2-oxoacetamido)-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicAcid (A630310), which is used in the preparation of Cephalosporin C (C258750), an antibiotic used to study the effect of transpeptidase expression, binding, and inhibition on bacterial cell wall mucopeptide synthesis. Group: Biochemicals. Grades: Highly Purified. CAS No. 102253-97-4. Pack Sizes: 2.5g, 5g. Molecular Formula: C12H7N3O2S3. US Biological Life Sciences.
Worldwide
D-Luciferin 99+% (HPLC)
D-Luciferin 99+% (HPLC). Group: Biochemicals. Alternative Names: (S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4-carboxylicacid; Firefly Luciferin; Beetle Luciferin. Grades: Reagent Grade. CAS No. 2591-17-5. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.
Worldwide
D-Luciferin free acid, 98+%
Identity (IR): Group: Biochemicals. Alternative Names: (S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4-carboxylicacid; Firefly Luciferin; Beetle Luciferin. Grades: Highly Purified. CAS No. 2591-17-5. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences.
WEHI-539, a selective BCL-XL inhibitor that can be function as a single-agent inducer of apoptosis while sparing normal cells, it leads to MOMP and apoptosis due to displacing bound activator BH3s or monomeric BAX and BAK from BCL-XL to induce the homo-ol. Synonyms: 4-Thiazolecarboxylicacid, 5-[3-[4-(aminomethyl)phenoxy]propyl]-2-[8-[2-(2-benzothiazolyl)hydrazinylidene]-5,6,7,8-tetrahydro-2-naphthalenyl]-; 5-[3-[4-(Aminomethyl)phenoxy]propyl]-2-[8-[2-(2-benzothiazolyl)hydrazinylidene]-5,6,7,8-tetrahydro-2-naphthalenyl]-4-thiazolecarboxylicacid; WEHI 539; WEHI539; 5-(3-(4-(aminomethyl)phenoxy)propyl)-2-(8-(2-(benzo[d]thiazol-2-yl)hydrazineylidene)-5,6,7,8-tetrahydronaphthalen-2-yl)thiazole-4-carboxylicacid. Grades: ≥95%. CAS No. 1431866-33-9. Molecular formula: C31H29N5O3S2. Mole weight: 583.73.
WEHI-539 hydrochloride
WEHI-539 is a selective BCL-XL inhibitor that can function as a single-agent inducer of apoptosis while sparing normal cells. WEHI-539 provokes BAK-mediated apoptosis in BCL-XL-dependent cells. Synonyms: 4-Thiazolecarboxylicacid, 5-[3-[4-(aminomethyl)phenoxy]propyl]-2-[8-[2-(2-benzothiazolyl)hydrazinylidene]-5,6,7,8-tetrahydro-2-naphthalenyl]-, hydrochloride (1:1); 5-(3-(4-(aminomethyl)phenoxy)propyl)-2-(8-(2-(benzo[d]thiazol-2-yl)hydrazineylidene)-5,6,7,8-tetrahydronaphthalen-2-yl)thiazole-4-carboxylicacid hydrochloride; WEHI-539 HCl; 5-{3-[4-(Aminomethyl)phenoxy]propyl}-2-[8-(1,3-benzothiazol-2-ylhydrazono)-5,6,7,8-tetrahydro-2-naphthalenyl]-1,3-thiazole-4-carboxylicacid hydrochloride (1:1); WEHI539 hydrochloride; WEHI 539 hydrochloride. Grades: ≥95%. CAS No. 2070018-33-4. Molecular formula: C31H29N5O3S2.HCl. Mole weight: 620.18.
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