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It is a fluorescent adenosine-containing compound commonly used to detect DNA/RNA modifications or to add synthetic oligonucleotide blocks. Synonyms: 5'-DMT-2'-tBDSilyl Adenosine (n-bz); 2'-O-TBDMS-5'-O-DMT-N6-Bz adenosine; N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine; 5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]adenosine; N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)adenosine; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)-N-benzoyladenosine. Grade: ≥95%. CAS No. 81265-93-2. Molecular formula: C44H49N5O7Si. Mole weight: 787.97.
2'-O-tert-butyldimethylsilyl-N4-Benzoyl-cytidine
2'-O-tert-butyldimethylsilyl-N4-Benzoyl-cytidine is a complex and multifunctional nucleoside analog extensively used in pharmaceutical applications to counter cytidine-sensitive viruses, including hepatitis B and C infections. The compound serves as a significant precursor for the synthesis of modified RNA-based therapies that have promising curative effects for genetic disorders and cancer treatments. Its diverse chemical properties make it an essential and indispensable agent for investigating various antiviral mechanisms that could pave the way for novel and innovative drug discovery. Synonyms: 2'-TBDMS-Bz-rC; N4-Benzoyl-2'-O-tert-butyldimethylsilylcytidine; N-Benzoyl-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]cytidine; Cytidine, N-benzoyl-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-. Grade: ≥97% by HPLC. CAS No. 185398-21-4. Molecular formula: C22H31N3O6Si. Mole weight: 461.58.
5'-O-DMT-2'-O-(tertbutyldimethylsilyl)-N6-Benzoyl-L-Adenosine is a potent adenosine analog commonly used in biomedical research. It acting as a versatile chemical tool for studying adenosine receptors and their signaling pathways. Additionally, it finding applications in the development of new drugs targeting adenosine-related diseases, such as inflammation is asthma, cardiovascular disorders is and cancer. Synonyms: 5'-O-DMT-2'-O-TBDMS-N6-Bz-L-rA; 5'-O-DMT-2'-O-TBDMS-L-rA(Bz); N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-L-adenosine; N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)-L-adenosine. Grade: ≥97% by HPLC. Molecular formula: C44H49N5O7Si. Mole weight: 787.99.
2'-O-tert-Butyl(dimethyl)silyl-7-O-triethylsilyl-2-debenzoyl-4-desacetyl Paclitaxel is one of Paclitaxel intermediates. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Synonyms: (αR,βS)-β-(Benzoylamino)-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6-(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-Dodecahydro-11,12,12b-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; [2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-β-(Benzoylamino)-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]benzenepropanoic Acid 6-(Acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11,12,12b-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; 4-deacetyl-2-debenzoyl-2'-O-tert-butyldimethylsilyl-7-O-(triethylsilyl)taxol; 2'-tert-butyldimethylsilyl-2-debenzoyl-4-deacetyl-7-(triethylsilyl)paclitaxel. Grade: 98%. CAS No. 160768-75-2. Molecular formula: C50H73NO12Si2. Mole weight: 936.28
5'-O-DMT-2'-O-TBDMS-N6-Benzoyl-L-Adenosine 3'-CE phosphoramidite is a crucial reagent used in the synthesis of oligonucleotides for biomedical research. It enables the efficient introduction of N6-benzoyl-L-Adenosine residues into the oligonucleotide chain, thus allowing the study of adenosine-modified nucleic acids. This product finds applications in drug discovery, gene therapy, and understanding diseases related to adenosine signaling pathways. Synonyms: Benzamide, N-[9-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-9H-purin-6-yl]-; N-Benzoyl-9-{5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-O-[dimethyl(2-methyl-2-propanyl)silyl]-β-L-ribofuranosyl}-9H-purin-6-amine; DMT-2'-O-TBDMS-L-rA(Bz) Phosphoramidite; 5'-O-DMTr-2'-O-TBDMS-L-A(Bz)-3'-CE-Phosphoramidite; N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-L-adenosine-3'-cyanoethyl Phosphoramidite. Grade: ≥98% by HPLC. CAS No. 1803193-36-3. Molecular formula: C53H66N7O8PSi. Mole weight: 988.21.
7-O-(Triethylsilyl)-2'-O-tert-butyl(dimethyl)silyl-2-debenzoyl-[2,4]oxol Paclitaxel is an intermediate in the synthesis of Paclitaxel, which is a chemotherapy medication used to treat a number of types of cancer. Synonyms: Benzenepropanoic acid, β-(benzoylamino)-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (2aS,3R,5S,5aS,7R,10S,12S,12aS,12bR)-2a,7-bis(acetyloxy)-2a,3,4,5,5a,6,7,10,11,12,12a,12b-dodecahydro-3,12-dihydroxy-5a,9,13,13-tetramethyl-6-oxo-5-[(triethylsilyl)oxy]-8,12-methano-2H-cyclodec[cd]isobenzofuran-10-yl ester, (αR,βS)-; (2α,5β,7β,10β,13α)-4,10-Diacetoxy-1,5-dihydroxy-9-oxo-7-[(triethylsilyl)oxy]-2,20-epoxytax-11-en-13-yl (2R,3S)-3-(benzoylamino)-2-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-3-phenylpropanoate. Molecular formula: C52H75NO13Si2. Mole weight: 978.32.
7-O-(Triethylsilyl)-2'-O-tert-butyl(dimethyl)silyl-2-debenzoyl Paclitaxel is a derivative of Paclitaxel, which is a chemotherapy medication used to treat a number of types of cancer. Synonyms: (αR,βS)-β-(Benzoylamino)-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11,12-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; 2'-(Tert-butyldimethylsilyl)-2-debenzoyl-7-(triethylsilyl)paclitaxel; (2α,5β,7β,10β,13α)-4,10-Diacetoxy-1,2-dihydroxy-9-oxo-7-[(triethylsilyl)oxy]-5,20-epoxytax-11-en-13-yl (2R,3S)-3-(benzoylamino)-2-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-3-phenylpropanoate. Grade: ≥95%. CAS No. 162459-94-1. Molecular formula: C52H75NO13Si2. Mole weight: 978.32.
7-O-(Triethylsilyl)-2'-O-tert-butyl(dimethyl)silyl-4-desacetyl-2-debenzoyl-[2,4]oxol Paclitaxel is an impurity of Paclitaxel, which is a chemotherapy medication used to treat a number of types of cancer. Synonyms: (αR,βS)-β-[Benzoylamino]-α-[[(1,1-dimethylethoxy)carbonyl]oxy]-benzenepropanoic Acid (2aS,3R,5S,5aS,7R,10S,12S,12aS,12bR)-2a,7-Bis(acetyloxy)-2a,3,4,5,5a,6,7,10,11,12,12a,12b-dodecahydro-3,12-dihydroxy-5a,9,13,13-tetramethyl-6-oxo-5-[(triethylsilyl)oxy]-8,12-methano-2H-cyclodec[cd]isobenzofuran-10-yl Ester; (2α,5β,7β,10β,13α)-10-Acetoxy-1,4,5-trihydroxy-9-oxo-7-[(triethylsilyl)oxy]-2,20-epoxytax-11-en-13-yl (2R,3S)-3-(benzoylamino)-2-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-3-phenylpropanoate; Benzenepropanoic acid, β-(benzoylamino)-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (2aS,3R,5S,5aS,7R,10S,12S,12aS,12bR)-7-(acetyloxy)-2a,3,4,5,5a,6,7,10,11,12,12a,12b-dodecahydro-2a,3,12-trihydroxy-5a,9,13,13-tetramethyl-6-oxo-5-[(triethylsilyl)oxy]-8,12-methano-2H-cyclodec[cd]isobenzofuran-10-yl ester, (αR,βS)-. Molecular formula: C50H73NO12Si2. Mole weight: 936.28.
7-O-(Triethylsilyl)-2'-O-tert-butyl(dimethyl)silyl-5-acetyl-4-desacetyl-2-debenzoyl-[2,4]oxol Paclitaxel is an intermediate in the synthesis of Paclitaxel, which is a chemotherapy medication used to treat a number of types of cancer. Synonyms: Benzenepropanoic acid, β-(benzoylamino)-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (2aS,3R,5S,5aS,7R,10S,12S,12aS,12bR)-3,7-bis(acetyloxy)-2a,3,4,5,5a,6,7,10,11,12,12a,12b-dodecahydro-2a,12-dihydroxy-5a,9,13,13-tetramethyl-6-oxo-5-[(triethylsilyl)oxy]-8,12-methano-2H-cyclodec[cd]isobenzofuran-10-yl ester, (αR,βS)-; (2α,5β,7β,10β,13α)-5,10-Diacetoxy-1,4-dihydroxy-9-oxo-7-[(triethylsilyl)oxy]-2,20-epoxytax-11-en-13-yl (2R,3S)-3-(benzoylamino)-2-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-3-phenylpropanoate. Molecular formula: C52H75NO13Si2. Mole weight: 978.32.
7-O-(Triethylsilyl)-2'-O-tert-butyl(dimethyl)silyl-5-benzoyl-4-desacetyldebenzoyl-[2,4]oxol Paclitaxel is an intermediate in the synthesis of Paclitaxel, which is a chemotherapy medication used to treat a number of types of cancer. Synonyms: Benzenepropanoic acid, β-(benzoylamino)-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (2aS,3R,5S,5aS,7R,10S,12S,12aS,12bR)-7-(acetyloxy)-3-(benzoyloxy)-2a,3,4,5,5a,6,7,10,11,12,12a,12b-dodecahydro-2a,12-dihydroxy-5a,9,13,13-tetramethyl-6-oxo-5-[(triethylsilyl)oxy]-8,12-methano-2H-cyclodec[cd]isobenzofuran-10-yl ester, (αR,βS)-; (2α,5β,7β,10β,13α)-10-Acetoxy-13-{[(2R,3S)-3-(benzoylamino)-2-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-3-phenylpropanoyl]oxy}-1,4-dihydroxy-9-oxo-7-[(triethylsilyl)oxy]-2,20-epoxytax-11-en-5-yl benzoate. Molecular formula: C57H77NO13Si2. Mole weight: 1040.39.
7-O-(Triethylsilyl)-2'-O-tert-butyl(dimethyl)silyl Paclitaxel is a derivative of Paclitaxel, which is a chemotherapy medication used to treat a number of types of cancer. Synonyms: (αR,βS)-β-(Benzoylamino)-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; 2'-(tert-butyldimethylsilyl)-7-(triethylsilyl)paclitaxel. Grade: 95%. CAS No. 156413-61-5. Molecular formula: C59H79NO14Si2. Mole weight: 1082.42.
Cytidine, N-benzoyl-3'-deoxy-2'-O-[(1,?1-dimethylethyl)?dimethylsilyl]?-3'-[[(4-methoxyphenyl)?diphenylmethyl]?amino]?-, 5'-[2-cyanoethyl bis(1-methylethyl)?phosphoramidite] (9CI) exhibits significant antiviral properties against various infections, including hepatitis C virus (HCV) and HIV. Mechanistically, its efficacy is due to mimicking nucleosides found in RNA, thereby halting viral replication. Notably, it represents a crucial nucleoside analogue for RNA interference (RNAi) and antisense therapy, with the added benefit of broad-spectrum antiviral activity. This product is an essential tool for researchers, clinicians, and virologists in developing effective pharmaceutical interventions for viral infections. Synonyms: ((2S,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-((tert-butyldimethylsilyl)oxy)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 256485-58-2. Molecular formula: C51H65N6O7PSi. Mole weight: 933.16.
Protected Paclitaxel. An antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. Group: Biochemicals. Alternative Names: (αR, βS)- β - (Benzoylamino) -α -[[ (1, 1-dimethylethyl) dimethylsilyl]oxy]-benzenepropanoic Acid (2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS)-6, 12b-Bis(acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-11-hydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-yl Ester. Grades: Highly Purified. CAS No. 156413-61-5. Pack Sizes: 25mg. US Biological Life Sciences.
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