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It is a fluorescent adenosine-containing compound commonly used to detect DNA/RNA modifications or to add synthetic oligonucleotide blocks. Synonyms: 2'-O-TBDMS-5'-O-DMT-N6-Bz adenosine; N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine; 5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine; N-Benzoyl-5'-O-[bis (4-methoxyphenyl) phenylmethyl]-2'-O-[ (1, 1-dimethylethyl) dimethylsilyl]adenosine; N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)adenosine; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)-N-benzoyladenosine. Grades: ≥95%. CAS No. 81265-93-2. Molecular formula: C44H49N5O7Si. Mole weight: 787.97.
2'-O-tert-butyldimethylsilyl-N4-Benzoyl-cytidine
2'-O-tert-butyldimethylsilyl-N4-Benzoyl-cytidine is a complex and multifunctional nucleoside analog extensively used in pharmaceutical applications to counter cytidine-sensitive viruses, including hepatitis B and C infections. The compound serves as a significant precursor for the synthesis of modified RNA-based therapies that have promising curative effects for genetic disorders and cancer treatments. Its diverse chemical properties make it an essential and indispensable agent for investigating various antiviral mechanisms that could pave the way for novel and innovative drug discovery. Synonyms: 2'-TBDMS-Bz-rC; N4-Benzoyl-2'-O-tert-butyldimethylsilylcytidine; N-Benzoyl-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]cytidine; Cytidine, N-benzoyl-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-. Grades: ≥97% by HPLC. CAS No. 185398-21-4. Molecular formula: C22H31N3O6Si. Mole weight: 461.58.
5'-O-DMT-N4-Benzoyl-3'-O-tert-butyldimethylsilyl-cytidine 2'-CE phosphoramidite, a highly acclaimed reagent in the realm of biomedicine, exhibits unparalleled significance. Notably, this phosphoramidite derivative finds widespread employment in the synthesis of altered oligonucleotides, exuding immense promise for gene therapy, drug conveyance, and diagnostic modalities. Synonyms: N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 2'-CE phosphoramidite; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; 3'-TBDMS-Bz-rC Phosphoramidite; 3'-O-TBDMS-5'-O-DMT-N4-Bz-rC CED phosphoramidite. Grades: ≥97% by HPLC. CAS No. 129470-47-9. Molecular formula: C52H66N5O9PSi. Mole weight: 964.17.
N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine, an influential therapeutic agent, stands as a formidable solution for combating viral infections such as hepatitis C and HIV. By harmoniously intertwining the antiviral attributes of cytidine with the defensive capabilities endowed by tert-butyldimethylsilyl and DMT groups, this compound markedly amplifies drug sturdiness and effectiveness. Synonyms: 5'-DMT-3'-TBDMS-Bz-rC; N4-Benzyl-3'-O-t-butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)cytidine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-Cytidine; N4-Bz-5'-O-DMT-3'-O-TBDMS-cytidine. Grades: ≥98% by HPLC. CAS No. 81246-78-8. Molecular formula: C43H49N3O8Si. Mole weight: 763.95.
N4-benzoyl-5'-O-tert-Butyldimethylsilyl-2'-deoxycytidine, a potent antitumor agent, offers therapy for an array of cancers like metastatic breast cancer, non-small cell lung cancer, pancreatic cancer, and bladder cancer. Its mechanism of action involves inhibiting DNA synthesis by interrupting the replication of DNA strands. By integrating itself into these strands, it results in premature chain termination. The compound thus offers a promising avenue for cancer therapy. Synonyms: 5'-O-TBDMS-N4-Bz-dc; 5'-O-TBDMS-N4-Benzoyl-2'-deoxycytidine; N-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxycytidine; N-Bz-5'-O-TBS dC; Cytidine, N-benzoyl-2'-deoxy-5'-O-[(1,1-dimethylethyl)dimethylsilyl]-; N-Benzoyl-2'-deoxy-5'-O-[dimethyl(2-methyl-2-propanyl)silyl]cytidine. Grades: ≥97% by HPLC. CAS No. 51549-36-1. Molecular formula: C22H31N3O5Si. Mole weight: 445.58.
N6-Benzoyl-2'-O-tert-butyldimethylsilyladenosine
N6-Benzoyl-2'-O-tert-butyldimethylsilyladenosine, a remarkable and potent biomedicine, stands as a beacon of hope in the fight against viral infections, including hepatitis C and HIV. Through meticulous investigation, scientists have unveiled its profound antiviral prowess, effectively hindering viral replication. By skillfully targeting specific viral enzymes, it adeptly curtails viral load while bolstering the body's immune response. Synonyms: 2'-TBDMS-Bz-rA; 2'-O-tert-butyldimethylsilyl-N6-Benzoyl-adenosine; N-Benzoyl-2'-O-(tert-butyldimethylsilyl)adenosine; Adenosine, N-benzoyl-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-; N-Benzoyl-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]adenosine; N-(9-((2R,3R,4R,5R)-3-((tert-Butyldimethylsilyl)oxy)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide. Grades: ≥97% by HPLC. CAS No. 69504-07-0. Molecular formula: C23H31N5O5Si. Mole weight: 485.61.
N6-Benzoyl-5'-O-tert-Butyldimethylsilyl-2'-deoxyadenosine, a synthetic adenosine analog, finds its application in curbing viral infections. It presents inhibitory activities against multiple viruses like HIV-1 and Hepatitis B, restricting their replication by imposing a halt on viral DNA synthesis. Interestingly, this antiviral agent's remedial prowess towards various diseases caused by viruses has consistently stirred researchers' intrigue. Synonyms: 5'-TBDMS-Bz-dA; N6-benzoyl-5'-O-(tert-butyldimethylsilyl)-2'-deoxyadenosine; N-Benzoyl-5'-O-(tert-butyldimethylsilyl)-2'-deoxyadenosine; N-(9-((2R,4S,5R)-5-(((tert-Butyldimethylsilyl)oxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide; Adenosine, N-benzoyl-2'-deoxy-5'-O-[(1,1-dimethylethyl)dimethylsilyl]-. Grades: ≥97% by HPLC. CAS No. 51549-39-4. Molecular formula: C23H31N5O4Si. Mole weight: 469.61.
2'-O-tert-Butyl(dimethyl)silyl-7-O-triethylsilyl-2-debenzoyl-4-desacetyl Paclitaxel is one of Paclitaxel intermediates. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Synonyms: (αR,βS)-β-(Benzoylamino)-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6-(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-Dodecahydro-11,12,12b-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; [2aR-[2aα , 4β , 4aβ , 6β , 9α (α R*, β S*) , 11α , 12α , 12aα , 12bα ]]-β - (Benzoylamino) -α -[[ (1, 1-dimethylethyl) dimethylsilyl]oxy]benzenepropanoic Acid 6-(Acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11,12,12b-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; 4-deacetyl-2-debenzoyl-2'-O-tert-butyldimethylsilyl-7-O-(triethylsilyl)taxol; 2'-tert-butyldimethylsilyl-2-debenzoyl-4-deacetyl-7-(triethylsilyl)paclitaxel. Grades: 98%. CAS No. 160768-75-2. Molecular formula: C50H73NO12Si2. Mole weight: 936.28.
7-O-(Triethylsilyl)-2'-O-tert-butyl(dimethyl)silyl-2-debenzoyl-[2,4]oxol Paclitaxel is an intermediate in the synthesis of Paclitaxel, which is a chemotherapy medication used to treat a number of types of cancer. Synonyms: Benzenepropanoic acid, β-(benzoylamino)-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (2aS,3R,5S,5aS,7R,10S,12S,12aS,12bR)-2a,7-bis(acetyloxy)-2a,3,4,5,5a,6,7,10,11,12,12a,12b-dodecahydro-3,12-dihydroxy-5a,9,13,13-tetramethyl-6-oxo-5-[(triethylsilyl)oxy]-8,12-methano-2H-cyclodec[cd]isobenzofuran-10-yl ester, (αR,βS)-; (2α, 5β, 7β, 10β, 13α)-4, 10-Diacetoxy-1, 5-dihydroxy-9-oxo-7-[(triethylsilyl)oxy]-2, 20-epoxytax-11-en-13-yl (2R,3S)-3-(benzoylamino)-2-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-3-phenylpropanoate. Molecular formula: C52H75NO13Si2. Mole weight: 978.32.
7-O-(Triethylsilyl)-2'-O-tert-butyl(dimethyl)silyl-2-debenzoyl Paclitaxel is a derivative of Paclitaxel, which is a chemotherapy medication used to treat a number of types of cancer. Synonyms: (αR,βS)-β-(Benzoylamino)-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11,12-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; 2'-(Tert-butyldimethylsilyl)-2-debenzoyl-7-(triethylsilyl)paclitaxel; (2α, 5β, 7β, 10β, 13α)-4, 10-Diacetoxy-1, 2-dihydroxy-9-oxo-7-[(triethylsilyl)oxy]-5, 20-epoxytax-11-en-13-yl (2R,3S)-3-(benzoylamino)-2-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-3-phenylpropanoate. Grades: ≥95%. CAS No. 162459-94-1. Molecular formula: C52H75NO13Si2. Mole weight: 978.32.
7-O-(Triethylsilyl)-2'-O-tert-butyl(dimethyl)silyl-4-desacetyl-2-debenzoyl-[2,4]oxol Paclitaxel is an impurity of Paclitaxel, which is a chemotherapy medication used to treat a number of types of cancer. Synonyms: (αR,βS)-β-[Benzoylamino]-α-[[(1,1-dimethylethoxy)carbonyl]oxy]-benzenepropanoic Acid (2aS,3R,5S,5aS,7R,10S,12S,12aS,12bR)-2a,7-Bis(acetyloxy)-2a,3,4,5,5a,6,7,10,11,12,12a,12b-dodecahydro-3,12-dihydroxy-5a,9,13,13-tetramethyl-6-oxo-5-[(triethylsilyl)oxy]-8,12-methano-2H-cyclodec[cd]isobenzofuran-10-yl Ester; (2α, 5β, 7β, 10β, 13α)-10-Acetoxy-1, 4, 5-trihydroxy-9-oxo-7-[(triethylsilyl)oxy]-2, 20-epoxytax-11-en-13-yl (2R,3S)-3-(benzoylamino)-2-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-3-phenylpropanoate; Benzenepropanoic acid, β-(benzoylamino)-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (2aS,3R,5S,5aS,7R,10S,12S,12aS,12bR)-7-(acetyloxy)-2a,3,4,5,5a,6,7,10,11,12,12a,12b-dodecahydro-2a,3,12-trihydroxy-5a,9,13,13-tetramethyl-6-oxo-5-[(triethylsilyl)oxy]-8,12-methano-2H-cyclodec[cd]isobenzofuran-10-yl ester, (αR,βS)-. Molecular formula: C50H73NO12Si2. Mole weight: 936.28.
7-O-(Triethylsilyl)-2'-O-tert-butyl(dimethyl)silyl-5-acetyl-4-desacetyl-2-debenzoyl-[2,4]oxol Paclitaxel is an intermediate in the synthesis of Paclitaxel, which is a chemotherapy medication used to treat a number of types of cancer. Synonyms: Benzenepropanoic acid, β-(benzoylamino)-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (2aS,3R,5S,5aS,7R,10S,12S,12aS,12bR)-3,7-bis(acetyloxy)-2a,3,4,5,5a,6,7,10,11,12,12a,12b-dodecahydro-2a,12-dihydroxy-5a,9,13,13-tetramethyl-6-oxo-5-[(triethylsilyl)oxy]-8,12-methano-2H-cyclodec[cd]isobenzofuran-10-yl ester, (αR,βS)-; (2α, 5β, 7β, 10β, 13α)-5, 10-Diacetoxy-1, 4-dihydroxy-9-oxo-7-[(triethylsilyl)oxy]-2, 20-epoxytax-11-en-13-yl (2R,3S)-3-(benzoylamino)-2-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-3-phenylpropanoate. Molecular formula: C52H75NO13Si2. Mole weight: 978.32.
7-O-(Triethylsilyl)-2'-O-tert-butyl(dimethyl)silyl-5-benzoyl-4-desacetyldebenzoyl-[2,4]oxol Paclitaxel is an intermediate in the synthesis of Paclitaxel, which is a chemotherapy medication used to treat a number of types of cancer. Synonyms: Benzenepropanoic acid, β-(benzoylamino)-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (2aS,3R,5S,5aS,7R,10S,12S,12aS,12bR)-7-(acetyloxy)-3-(benzoyloxy)-2a,3,4,5,5a,6,7,10,11,12,12a,12b-dodecahydro-2a,12-dihydroxy-5a,9,13,13-tetramethyl-6-oxo-5-[(triethylsilyl)oxy]-8,12-methano-2H-cyclodec[cd]isobenzofuran-10-yl ester, (αR,βS)-; (2α, 5β, 7β, 10β, 13α)-10-Acetoxy-13-{[(2R, 3S)-3-(benzoylamino)-2-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-3-phenylpropanoyl]oxy}-1, 4-dihydroxy-9-oxo-7-[(triethylsilyl)oxy]-2, 20-epoxytax-11-en-5-yl benzoate. Molecular formula: C57H77NO13Si2. Mole weight: 1040.39.
7-O-(Triethylsilyl)-2'-O-tert-butyl(dimethyl)silyl Paclitaxel is a derivative of Paclitaxel, which is a chemotherapy medication used to treat a number of types of cancer. Synonyms: (αR,βS)-β-(Benzoylamino)-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; 2'-(tert-butyldimethylsilyl)-7-(triethylsilyl)paclitaxel. Grades: 95%. CAS No. 156413-61-5. Molecular formula: C59H79NO14Si2. Mole weight: 1082.42.
Cytidine, N-benzoyl-3'-deoxy-2'-O-[ (1, ?1-dimethylethyl) ?dimethylsilyl]?-3'-[[ (4-methoxyphenyl) ?diphenylmethyl]?amino]?-, 5'-[2-cyanoethyl bis(1-methylethyl)?phosphoramidite] (9CI) exhibits significant antiviral properties against various infections, including hepatitis C virus (HCV) and HIV. Mechanistically, its efficacy is due to mimicking nucleosides found in RNA, thereby halting viral replication. Notably, it represents a crucial nucleoside analogue for RNA interference (RNAi) and antisense therapy, with the added benefit of broad-spectrum antiviral activity. This product is an essential tool for researchers, clinicians, and virologists in developing effective pharmaceutical interventions for viral infections. Synonyms: ( (2S, 3R, 4R, 5R) -5- (4-benzamido-2-oxopyrimidin-1 (2H) -yl) -4- ( (tert-butyldimethylsilyl) oxy) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 256485-58-2. Molecular formula: C51H65N6O7PSi. Mole weight: 933.16.
N-(9-((2R,4S,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide is a biomedical product used for studying various diseases through its ability to inhibit specific enzymes. Synonyms: N-Benzoyl-2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-adenosine. Grades: 98%. CAS No. 51549-40-7. Molecular formula: C23H31N5O4Si. Mole weight: 469.61.
Protected Paclitaxel. An antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. Group: Biochemicals. Alternative Names: (αR, βS)- β - (Benzoylamino) -α -[[ (1, 1-dimethylethyl) dimethylsilyl]oxy]-benzenepropanoic Acid (2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS)-6, 12b-Bis(acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-11-hydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-yl Ester. Grades: Highly Purified. CAS No. 156413-61-5. Pack Sizes: 25mg. US Biological Life Sciences.
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