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| Product | Description | |
|---|---|---|
| Berberine | Berberine is a quaternary ammonium salt from the protoberberine group of benzylisoquinoline alkaloids, it is found in such plants as herb of Coptis chinensis Franch. Berberine has been shown to possess anti-inflammatory and antitumor properties in some in vitro systems. Uses: Anti-inflammatory; antitumo. Synonyms: 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)- (8CI); Umbellatine(6CI); Berbericine; Berberin; Majarine; Thalsine; Umbellatin; 5, 6-Dihydro-9, 10-di methoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium. Grades: >98%. CAS No. 2086-83-1. Molecular formula: C20H18NO4. Mole weight: 336.4. |  |
| Berberine | Berberine (Natural Yellow 18) is an alkaloid isolated from the Chinese herbal medicine Huanglian, as an antibiotic. Berberine (Natural Yellow 18) induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Berberine (Natural Yellow 18) has antineoplastic properties. Group: Inhibitors. Alternative Names: Berbericine. CAS No. 2086-83-1. Molecular formula: C20H18NO4. Mole weight: 336.37. Appearance: White to yellow crystals. Purity: 0.99. IUPACName: 16, 17-Dimethoxy-5, 7-dioxa-13-azoniapentacyclo[11.8.0.02, 10.04, 8.015, 20]henicosa-1(13), 2, 4(8), 9, 14, 16, 18, 20-octaene. Canonical SMILES: COC1=C (C2=C[N+]3=C (C=C2C=C1)C4=CC5=C (C=C4CC3)OCO5)OC. Density: 1.2976 g/cm³. Catalog: ACM2086831. |  |
| Berberine chloride | Berberine chloride is an alkaloid that acts as an antibiotic. Berberine chloride induces reactive oxygen species ( ROS ) generation and inhibits DNA topoisomerase. Antineoplastic properties [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Natural Yellow 18 chloride. CAS No. 633-65-8. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-18258. |  |
| Berberine chloride | Berberine chloride is an alkaloid that acts as an antibiotic. Berberine chloride induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties. Group: Inhibitors. Alternative Names: Berberine hydrochloride. CAS No. 633-65-8. Molecular formula: C20H18ClNO4. Mole weight: 371.8. Appearance: Solid. Purity: 95%+. Canonical SMILES: COC1=C (OC)C2=C[N+]3=C (C (C (CC3)=C4)=CC5=C4OCO5)C=C2C=C1. [Cl-]. Catalog: ACM633658. | |
| Berberine Chloride (Berberine) | A highly potent and selective oxysterol EBI2 (GPR183) agonist (Kd) = 450pM in a saturation binding assay, and EC50 = 140 pM over EC50 = 2.1nM for its enantiomer, 7b,25-OHC, in a GTP-gamma S binding assay). Dose-dependently suppresses forskolin-induced cAMP accumulation in an EBI2-expressing SK-N-MC/CRE-b-galactosidase cell line (IC50 = 2nM), but not in control cells. Stimulates migration of LPS-activated spleen B-cells and anti-CD3/CD28-activated CD4+ T-cells in a dose-dependent manner. In addition, pharmacological inhibition of its biosynthesis in vivo by Clotrimazole, a CYP7B1inhibitor, promotes the migration of adoptively transferred pre-activated B cells to the T/B boundary, mimicking the phenotype of pre-activated B cells in EBI2-deficient mice. Group: Biochemicals. Grades: Highly Purified. CAS No. 633-65-8. Pack Sizes: 25mg. US Biological Life Sciences. |  Worldwide |
| Berberine chloride dihyd | Berberine chloride dihyd. Uses: For analytical and research use. Group: Impurity standards. CAS No. 5956-60-5. Molecular Formula: C20H22ClNO6. Mole Weight: 407.85. Catalog: APB5956605. |  |
| Berberine chloride hydrate | 25g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C20H18ClNO4 ·xH2O. CAS No. 141433-60-5. Prepack ID 89981875-25g. Molecular Weight 371.81. See USA prepack pricing. |  |
| Berberine chloride hydrate | Berberine chloride hydrate (Natural Yellow 18 chloride hydrate) is an alkaloid that acts as an antibiotic. Berberine chloride hydrate induces reactive oxygen species ( ROS ) generation and inhibits DNA topoisomerase. Antineoplastic properties [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Natural Yellow 18 chloride hydrate. CAS No. 68030-18-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g; 5 g. Product ID: HY-17577. | |
| Berberine chloride hydrate | The plant-based alkaloid berberine has potential therapeutic applications for breast cancer, although a better understanding of the genes and cellular pathways regulated by this compound is needed to define the mechanism of its action in cancer treatment. In this review, the molecular targets of berberine in various cancers, particularly breast cancer, are discussed. Berberine was shown to be effective in inhibiting cell proliferation and promoting apoptosis in various cancerous cells. Some signaling pathways affected by berberine, including the MAP (mitogen-activated protein) kinase and Wnt/β-catenin pathways, are critical for reducing cellular migration and sensitivity to various growth factors. Treatment with BBR(Berberine) in rats on the atherogenic diet reduced plasma total cholesterol and nonHDL cholesterol levels by 29%-33% and 31%-41%, respectively, with no significant differences being observed among the three doses. Berberine induced both apoptotic and autophagic death of HepG2 cells, which was associated with a significant activation of AMPK and an increased expression of the inactive form of acetyl-CoA carboxylase (ACC). Berberine did not show major effects on viability of HEK-293 embryonic kidney and HCT116 colon carcinoma cells and was not toxic in concentrations up to 20 μM. Berberine inhibited β-catenin transcriptional activity and attenuated anchorage-independent growth. As a result of berberine treatment, cellular levels of active β-catenin were reduced concomitant with an increase in the expression of E-cadherin. Synonyms: Natural Yellow 18. Grades: >98%. CAS No. 141433-60-5. Molecular formula: C20H18ClNO4. Mole weight: 371.81. | |
| Berberine Chloride (Natural Yellow 18, 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium) | An isoquinoline alkaloid that acts as an anticancer agent. It inhibits cell growth and induces apoptosis in a variety of cancer cell lines. It induces the most potent apoptosis in acute lymphoblastic leukemia (ALL) cells with both MDM2 overexpression and a wild-type (wt)-p53, whereas no pro-apoptotic effect was detected in ALL cells that were negative for MDM2 and wt-p53. Group: Biochemicals. Grades: Highly Purified. CAS No. 633-65-8. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| Berberine Demethylation Impurity1 | Berberine Demethylation Impurity1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 4668-19-3. Molecular Formula: C19H16ClNO4. Mole Weight: 357.79. Catalog: APB4668193. | |
| Berberine Extract | Berberine extract is prepared from the root of a low-growing relative of the peony, native to the mountains of China. Berberine extract is a dietary supplement that contains the natural plant substance berberine. Berberine extract is used frequently in non-traditional medical systems like Ayurvedic and Chinese herbal medicin. Group: Others. Mole weight: 371.82. Berberine Extract; Coptis chinensis Franch. Cat No: EXTC-032. |  |
| Berberine HCL Powder 97% Tritration | Berberine HCL Powder 97% Tritration (Berberis Aristata). |  CA, FL & NJ |
| Berberine hemisulfate | Berberine hemisulfate. Group: Biochemicals. Alternative Names: Berberine hydrogen sulphate. Grades: Highly Purified. CAS No. 633-66-9. Pack Sizes: 50g, 100g, 250g. Molecular Formula: C20H18NO4·½SO4. US Biological Life Sciences. | Worldwide |
| Berberine hydrochloride | 25g Pack Size. Group: Antibiotics, Bioactive Small Molecules, Quaternary Ammonium salts, Research Organics & Inorganics. Formula: C20H18ClNO4. CAS No. 633-65-8. Prepack ID 13172687-25g. Molecular Weight 371.81. See USA prepack pricing. | |
| Berberine hydrochloride | Berberine hydrochloride is an isoqinoline alkaloid and acts as a COX-2 inhibitor that exhibits chemopreventive activity against colon tumor formation. Study in humans and hamsters shows that berberine reduces total cholesterol, low-density lipoprotein (LDL) cholesterol, and triglycerides. It also inhibits c-Jun and suppresses inflammation and cancers. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Berberine chloride; Natural Yellow 18; Benzodioxide; Berberinium chloride. Grades: ≥ 98%. CAS No. 633-65-8. Molecular formula: C20H18ClNO4. Mole weight: 371.817. | |
| Berberine Hydrochloride | An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Also inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs. Group: Biochemicals. Alternative Names: 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium Chloride; Berberine Chloride; 7, 8, 13, 13a-Tetradehydro-9, 10-dimethoxy-2, 3- (methylenedioxy) berbinium Chloride; Berberine Hydrochloride; NSC 646666. Grades: Highly Purified. CAS No. 633-65-8. Pack Sizes: 25g. US Biological Life Sciences. | Worldwide |
| Berberine hydrogen sulphate | Berberine is a natural compound that has been shown to have anti-inflammatory and anticancer properties. It is the main component of berberine sulfate, which can be found in plants such as Coptis chinensis and goldenseal. Berberine sulfate has been shown to inhibit skin tumor formation by inhibiting nuclear DNA synthesis and tumor cell growth. Berberine sulfate also inhibits the production of p-nitrophenyl phosphate, a chemical that is used as an indicator for bacterial growth. Berberine sulfate binds to DNA polymerase and inhibits its activity, thereby preventing transcription of DNA into RNA. This compound can be used in chromatographic analysis and optical sensor systems to detect bacterial infections. Group: Other alkaloids. Alternative Names: Natural Yellow 18. CAS No. 633-66-9. Molecular formula: C20H18NO4·HSO4. Mole weight: 433.43 g/mol. Canonical SMILES: COC1=C (C2=C[N+]3=C (C=C2C=C1)C4=CC5=C (C=C4CC3)OCO5)OC. OS (=O) (=O)[O-]. Catalog: ACM633669. | |
| Berberine Impurity 1 | Berberine Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 430433-40-2. Molecular Formula: C18H22ClNO4. Mole Weight: 351.83. Catalog: APB430433402. | |
| Berberine Impurity 2 | Berberine Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2043361-62-0. Molecular Formula: C20H18NO5+. Mole Weight: 352.37. Catalog: APB2043361620. | |
| Berberine Impurity 3 Chloride | Berberine Impurity 3 Chloride. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C20H18ClNO4. Mole Weight: 371.82. Catalog: APB06872. | |
| Berberine Impurity 5 Chloride | Berberine Impurity 5 Chloride. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2363741-22-2. Molecular Formula: C18H16ClNO4. Mole Weight: 345.78. Catalog: APB2363741222. | |
| Berberine Impurity 6 | Berberine Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 65615-22-7. Molecular Formula: C16H14O4. Mole Weight: 270.28. Catalog: APB65615227. | |
| Berberine Impurity 7 | Berberine Impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 65615-23-8. Molecular Formula: C17H16O4. Mole Weight: 284.31. Catalog: APB65615238. | |
| Berberine Liposome | Berberine is an isoquinoline alkaloid, which are used in the treatment of tumors, diabetes, and cardiovascular diseases. This product is a PEGylated pre-formulated liposome with berberine. It is only for research purposes. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes. |  |
| Berberine Methyl | Berberine Methyl. Uses: For analytical and research use. Group: Impurity standards. CAS No. 38763-29-0. Molecular Formula: C20H16NO4+. Mole Weight: 334.35. Catalog: APB38763290. | |
| berberine reductase | Involved in alkaloid biosynthesis in Corydalis cava to give (R)-canadine with the opposite configuration to the precursor of berberine (see EC 1.3.3.8 tetrahydroberberine oxidase). Also acts on 7,8-dihydroberberine. Group: Enzymes. Synonyms: (R)-canadine synthase. Enzyme Commission Number: EC 1.5.1.31. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1513; berberine reductase; EC 1.5.1.31; (R)-canadine synthase. Cat No: EXWM-1513. | |
| Berberine sulfate | Berberine sulfate. Group: Biochemicals. Grades: Highly Purified. CAS No. 6190-33-6. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1mg. Molecular Formula: C40H42N2O15S. US Biological Life Sciences. | Worldwide |
| Berberine sulfate | Berberine sulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian, as an antibiotic. Berberine sulfate induces reactive oxygen species ( ROS ) generation and inhibits DNA topoisomerase. Berberine sulfate has antineoplastic properties. The sulfate form improves bioavailability [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Natural Yellow 18 sulfate. CAS No. 633-66-9. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-N0716B. | |
| Berberine Sulfate Hydrate (2:1:3) | Berberine Sulfate Hydrate is a plant alkaloid found in multiple plants such as goldenseal, barberry, goldthread, Oregon grape, tree turmeric and phellodendron. It inhibits the growth of multiple parasites and bacteria thus can be used for the treatment of infections. Uses: Orally admin berberine sulfate (350-700 mg/kg) was effective in treating candida albicans infections of the intestine in mice. Synonyms: Berberine sulfate trihydrate; Berberine sesquihydrate sulfate; T3MQ0UO932; Berberine sulfate [JAN]; 69352-97-2; Natural Yellow 18 sulphate; UNII-T3MQ0UO932; 316-41-6; Benzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium, 5,6-dihydro-9,10-dimethoxy-, sulfate (2:1), trihydrate; Benzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium, 5,6-dihydro-9,10-dimethoxy-, sulfate, hydrate (2:1:3); Berberine sulfate hydrate; BERBERINE SULFATE HYDRATE [JAN]; BERBERINE SULFATE TRIHYDRATE [MI]; Q27289626. CAS No. 69352-97-2. Molecular formula: 2C20H18NO4.3H2O.O4S. Mole weight: 822.844. | |
| Berberine Sulfate Trihydrate | . Uses: Orally admin berberine sulfate (350-700 mg/kg) was effective in treating candida albicans infections of the intestine in mice. Synonyms: Berbinium, 7,8,13,13A-Tetradehydro-9,10-Dimethoxy-2,3-(Methylenedioxy)-, Sulfate, Trihydrate. Grades: > 95%. CAS No. 6190-33-6. Molecular formula: C40H42N2O15S. Mole weight: 822.86. | |
| Berberine Tetrahydro | Berberine Tetrahydro. Uses: For analytical and research use. Group: Impurity standards. CAS No. 522-97-4. Molecular Formula: C20H21NO4. Mole Weight: 339.39. Catalog: APB522974. | |
| 8-Keto-berberine | 8-Keto-berberine is a natural product that is extracted from the plant Berberis aristata. It has been used as a reference material for HPLC standards, and is used in the screening of secondary metabolites and phytochemicals. 8-Keto-berberine has been shown to be bioactive, with antioxidant and anti-inflammatory properties. It also inhibits protein kinase C (PKC) activity, which may lead to its anti-cancer effects. 8-Keto-berberine is a secondary metabolite isolated from plants, and can be found in the CAS Registry Number 81397-08-2. Group: Other alkaloids. CAS No. 81397-08-2. Molecular formula: C20H17NO5. Mole weight: 351.4 g/mol. Canonical SMILES: CN1CCOC(C1)C2=NC=C(C=C2)Br.Cl. Catalog: ACM81397082. | |
| Dihydroberberine-2 | Dihydroberberine is a medicinal compound that has been found in human urine and has shown potential as an inhibitor of protein kinase activity. This analog of berberine has been studied for its anticancer properties, specifically in inducing apoptosis in leukemia and tumor cells. Dihydroberberine has been shown to be effective against various types of cancer in both human and animal models, making it a promising candidate for future cancer treatments. Additionally, this compound has been used in traditional Chinese medicine for centuries due to its anti-inflammatory properties and ability to regulate blood sugar levels. With its potent inhibition of kinase activity and promising anticancer effects, dihydroberberine holds great potential as a valuable addition to cancer treatment options. Group: Other alkaloids. CAS No. 120834-89-1. Molecular formula: C20H20NO4+. Mole weight: 338.4 g/mol. Canonical SMILES: COC1=C (C2=C (CC3=[N+] (C2)CCC4=CC5=C (C=C43)OCO5)C=C1)OC. Catalog: ACM120834891. | |
| DL-Tetrahydroberberine | Tetrahydroberberine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Tetrahydroberberine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling. Synonyms: 6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine, 5,8,13,13a-tetrahydro-9,10-dimethoxy-; 5,8,13,13a-Tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine; Berberine, 9-deoxy-16,17-dihydro-; Berbine, 9,10-dimethoxy-2,3-(methylenedioxy)-; (±)-Canadine; (±)-Tetrahydroberberine; Berberine, tetrahydro-; Canadine; dl-Canadine; NSC 36351; NSC 94918; Tetrahydroberberine; Tetrahydroberineper; Tetrahydroumbellatine; Xanthopuccine. Grades: ≥95%. CAS No. 522-97-4. Molecular formula: C20H21NO4. Mole weight: 339.38. | |
| Phellodendron Bark P.E. > 6% Berberine HPLC | Phellodendron Bark P.E. > 6% Berberine HPLC. | CA, FL & NJ |
| 2-Methoxythiophenol | 2-Methoxythiophenol is used in the synthesis of berberine-thiophenyl hybrids as multifunctional agents. Inhibition of acetylcholinesterase, butyrylcholinesterase and AB aggregation antioxidant activity. Group: Biochemicals. Alternative Names: 2-(Methoxy)benzothiol; 2-Mercaptoanisole; 2-Methoxybenzenethiol; 2-Methoxythiophenol; o-Methoxybenzenethiol; o-Methoxythiophenol. Grades: Highly Purified. CAS No. 7217-59-6. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| Barberry Extract | Barberry Extract. Applications: Used for health care products, dietary supplements, herb medecine to antihistamine and anti-allergy. Group: Others. Synonyms: Barberry Extract; 117-74-8; Berberis vulgaris L. CAS No. 117-74-8. Purity: 60% Berberine by HPLC. Appearance: Yellowish fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Bark. Species: Berberis vulgaris L. Barberry Extract; 117-74-8; Berberis vulgaris L.; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-127. | |
| Berberrubine chloride | Berberrubine chloride is an orally active metabolite of berberine. Berberrubine chloride alleviates mucosal lesions and inflammation in mouse colitis models. Berberrubine chloride has anti-inflammatory, anti-tumor, and antiviral activities [1] [1] [3]. Uses: Scientific research. Group: Natural products. CAS No. 15401-69-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125850. | |
| columbamine oxidase | An iron protein. Oxidation of the O-methoxyphenol structure forms the methylenedioxy group of berberine. Group: Enzymes. Synonyms: berberine synthase. Enzyme Commission Number: EC 1.21.3.2. CAS No. 95329-18-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1249; columbamine oxidase; EC 1.21.3.2; 95329-18-3; berberine synthase. Cat No: EXWM-1249. | |
| Isoquinoline | Isoquinoline is an analog of pyridine. Isoquinoline-based alkaloids, such as p-tolyl bisisoquinoline, phthaloyl isoquinoline, and naphthyl isoquinoline, exhibit anticancer activity. Berberine, an isoquinoline alkaloid, exerts anti-inflammatory effects in diabetic mice by downregulating the gene expression ratios of pro-/anti-inflammatory and Th1/Th2 cytokines. Additionally, some isoquinoline-based compounds also possess antidepressant, antibacterial, antimalarial, and anti- HIV activities [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 119-65-3. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-W012732. | |
| Jatrorrhizine hydrochloride | Jatrorrhizine hydrochloride is a naturally occurring compound, which has been shown to have hypoglycemic effects and can be used for the treatment of skin cancer. It is an analogue of berberine that inhibits mitochondrial membrane potential, leading to cell death by inhibiting energy metabolism and causing chromatographic analysis. Jatrorrhizine hydrochloride also inhibits the synthesis of proteins required for glycolysis, including hexokinase 2 (HK2), phosphofructokinase 1 (PFK1), and pyruvate kinase M2 (PKM2). This drug is metabolized by esterases or glucuronidases to form benzalkonium chloride or ginsenoside RG3. This active form binds to penicillin-binding protein, which may lead to metabolic disorders such as hepatic steatosis. Group: Other alkaloids. CAS No. 2106804-01-5. Molecular formula: C20H20NO4·HCl. Mole weight: 374.84 g/mol. Canonical SMILES: COC1=C (C2=C[N+]3=C (C=C2C=C1)C4=CC (=C (C=C4CC3)O)OC)OC. [Cl-]. Catalog: ACM2106804015. | |
| L-Leucine, reagent grade, ≥98% (HPLC) | L-Leucine has been used as an agonist of mechanistic target of rapamycin (mTOR) to determine whether AMPK/mTOR pathway is involved in berberine-mediated autophagy in J774A.1 cells. It has also been used for the selection of transformed cells. Group: Amino acids. Alternative Names: (S)-2-Amino-4-methylpentanoic acid. CAS No. 61-90-5. Molecular formula: (CH3)2CHCH2CH(NH2)CO2H. Mole weight: 131.17. Canonical SMILES: CC(C)C[C@H](N)C(O)=O. ECNumber: 200-522-0. Catalog: ACM61905-2. | |
| reticuline oxidase | Contains FAD. The enzyme from the plant Eschscholtzia californica binds the cofactor covalently. Acts on (S)-reticuline and related compounds, converting the N-methyl group into the methylene bridge ('berberine bridge') of (S)-tetrahydroprotoberberines. The product of the reaction, (S)-scoulerine, is a precursor of protopine, protoberberine and benzophenanthridine alkaloid biosynthesis in plants. Group: Enzymes. Synonyms: BBE; berberine bridge enzyme; berberine-bridge-forming enzyme; tetrahydroprotoberberine synthase. Enzyme Commission Number: EC 1.21.3.3. CAS No. 152232-28-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1250; reticuline oxidase; EC 1.21.3.3; 152232-28-5; BBE; berberine bridge enzyme; berberine-bridge-forming enzyme; tetrahydroprotoberberine synthase. Cat No: EXWM-1250. | |
| (-)-Scoulerin | (-)-Scoulerin is a heterotetracyclic compound that is the metabolite of scoulerine. It has been shown to inhibit topoisomerase, an enzyme that is involved in DNA replication and repair. (-)-Scoulerin has also been found to be a potent inhibitor of corydalis, which belongs to the plant family Papaveraceae and contains alkaloids such as berberine. This compound may have potential applications in treating cancer cells due to its ability to inhibit topoisomerase. Group: Other alkaloids. CAS No. 6451-73-6. Molecular formula: C19H21NO4. Mole weight: 327.37 g/mol. Canonical SMILES: COC1=C (C2=C (CC3C4=CC (=C (C=C4CCN3C2)OC)O)C=C1)O. Catalog: ACM6451736-1. | |
| tetrahydrocolumbamine 2-O-methyltransferase | Involved in the biosynthesis of the berberine alkaloids. Group: Enzymes. Synonyms: tetrahydrocolumbamine methyltransferase. Enzyme Commission Number: EC 2.1.1.89. CAS No. 93792-09-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1990; tetrahydrocolumbamine 2-O-methyltransferase; EC 2.1.1.89; 93792-09-7; tetrahydrocolumbamine methyltransferase. Cat No: EXWM-1990. | |
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