Bestatin Suppliers USA
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Product | Description | |
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Bestatin Quick inquiry Where to buy Suppliers range | Bestatin is a specific aminopeptidase B inhibitor produced by Streptomyces olivoreticuli. Bestatin is a potent aminopeptidase-B and leukotriene (LT) A4 hydrolase inhibitor used in the treatment of acute myelocytic leukemia. It exhibits potential immunomodulatory and antitumor activities. Uses: The treatment of acute myelocytic leukemia. Synonyms: Ubenimex. Grades: >98%. CAS No. 58970-76-6. Molecular formula: C16H24N2O4. Mole weight: 308.37. | |
Bestatin Quick inquiry Where to buy Suppliers range | Bestatin is "pseudo"-dipeptide isolated from Streptomyces olivreticuli in 1976. Bestatin is potent aminopeptidase B inhibitor with no carboxypeptidase activity. Bestatin acts as an immunomodulator by activation of macrophages and T-lymphocytes. Bestatin also exhibits good antitumor activity and is under clinical investigation. Group: Biochemicals. Grades: Highly Purified. CAS No. 58970-76-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Bestatin-d7 Quick inquiry Where to buy Suppliers range | Bestatin-d7 is the isotope labelled analog of Bestatin. Bestatin based inhibitors have novel binding mode in S1 pocket of essential malaria M1 metalloaminopeptidase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C16H17D7N2O4, Molecular Weight: 315.42. US Biological Life Sciences. | Worldwide |
Bestatin hydrochloride Quick inquiry Where to buy Suppliers range | Bestatin hydrochloride is a reversible inhibitor of aminopeptidase enzymes, namely Aminopeptidase B, Aminopeptidase M (CD13), and leucine aminopeptidase (LAP3). Inhibition of these proteins by bestatin correlates to apoptosis induction in oncogenic cells. Bestatin is also a potent inhibitor of leukotriene A4 hydrolase (LTA4). It is potentially used for cancer treatment. Uses: Peptide Inhibitors. CAS No. 65391-42-6. Product ID: R1028. | |
Bestatin hydrochloride Quick inquiry Where to buy Suppliers range | Bestatin hydrochloride. Group: Heterocyclic Organic Compound. Alternative Names: N-[(2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTYRYL]-L-LEUCINE HYDROCHLORIDE;N-(3R-AMINO-2S-HYDROXY-1-OXO-4-PHENYLBUTYL)-L-LEUCINE, MONOHYDROCHLORIDE;[(2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTANOYL]-L-LEUCINE HCL;[(2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTANOYL]-L-LEUCINE HYDROCHLORIDE;(AMINO-2-HYDROXY-4-PHENYLBUTYRYL)-L-LEUCINE HYDROCHLORIDE;BESTATIN HCL;BESTATIN HYDROCHLORIDE;N-(2S,3R-3-AMINO-2-HYDROXY-4-PHENYLBUTY- RYL)-L-LEUCINE HCL. CAS No. 65391-42-6. Product ID: ACM65391426. Molecular formula: C16H25ClN2O4. Mole weight: 344.83. Melting Point: 216-218°C. | |
Bestatin hydrochloride Quick inquiry Where to buy Suppliers range | Bestatin hydrochloride is a competitive aminopeptidase inhibitor, which is studied for use in the treatment of acute myelocytic leukemia. It has become a useful tool in elucidating the physiological role of some mammalian exopeptidases in the regulation of the immune system, in the growth of tumors and their invasion of surrounding tissues, and in the degradation of cellular proteins. Synonyms: Aminopeptidase inhibitor; leucine aminopeptidase; aminopeptidase B; NK-421. Grades: >98%. CAS No. 65391-42-6. Molecular formula: C16H24N2O4.HCl. Mole weight: 344.83. | |
Bestatin trifluoroacetate Quick inquiry Where to buy Suppliers range | Bestatin, also known as Ubenimex (INN), is a competitive protease inhibitor. It is an inhibitor of aminopeptidase B, leukotriene A4 hydrolase, aminopeptidase N. It is being studied for use in the treatment of acute myelocytic leukemia. Bestatin can be administered, with low toxicity, to cultured cells, intact animals and humans. It has become a useful tool in elucidating the physiological role of some mammalian exopeptidases in the regulation of the immune system, in the growth of tumors and their invasion of surrounding tissues, and in the degradation of cellular proteins. Synonyms: Ubenimex trifluoroacetate. Grades: >98%. CAS No. 223763-80-2. Molecular formula: C18H25F3N2O6. Mole weight: 422.4. | |
(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoic Acid Quick inquiry Where to buy Suppliers range | (2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoic acid is a component of a renin inhibitor and bestatin. Group: Biochemicals. Grades: Highly Purified. CAS No. 59554-14-2. Pack Sizes: 50mg, 100mg. Molecular Formula: C10H13NO3, Molecular Weight: 195.22. US Biological Life Sciences. | Worldwide |
(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoic acid-d7 Quick inquiry Where to buy Suppliers range | (2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoic acid-d7 is labelled (2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoic acid which is a component of a renin inhibitor and bestatin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C10H6D7NO3, Molecular Weight: 202.26. US Biological Life Sciences. | Worldwide |
Arphamenine B Quick inquiry Where to buy Suppliers range | Arphamenine B is a specific inhibitor of aminopeptidase B, which is first isolated from bacteria. Arphamenine B shares the same properties as the aminopeptidase inhibitors bestatin and amastatin, both of which enhance the immune response. Synonyms: Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, (αR)-; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxybenzenepropanoic acid; Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, [S-(R*,S*)]-; Arphamenin B. Grades: 95%. CAS No. 103900-19-2. Molecular formula: C16H24N4O4. Mole weight: 336.39. | |
Arphamenine B hemisulfate Quick inquiry Where to buy Suppliers range | Arphamenine B is a specific inhibitor of aminopeptidase B, which is first isolated from bacteria. Arphamenine B Hemisulfate is the hemisulfate form. Arphamenine B share the same property with aminopeptidase inhibitors bestatin and amastatin, they all enhance imune responses. Synonyms: Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, (αR)-, sulfate (2:1) (salt); Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, monohydrochloride, [S-(R*,S*)]-, sulfate (2:1) (salt); Arphamenine B sulfate; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxybenzenepropanoic acid, sulfate (2:1) (salt). Grades: ≥95%. CAS No. 144110-38-3. Molecular formula: C16H24N4O4·1/2H2SO4. Mole weight: 385.43. | |
ATRA-hydroxyimino Quick inquiry Where to buy Suppliers range | ATRA-hydroxyimino (CRABP-II ligand 1), the Retinoic acid (ATRA)-based moiety, binds to cIAP1 ligand (Bestatin) via a linker to form SNIPER to degrade CRABP-II in IMR-32 cells. Synonyms: ATRA-hydroxyimino; CRABP-II ligand 1. CAS No. 135325-47-2. Molecular formula: C20H27NO3. Mole weight: 329.43. | |
Ubenimex Quick inquiry Where to buy Suppliers range | Ubenimex (INN), also known more commonly as bestatin, is a competitive, reversible protease inhibitor. It is an inhibitor of arginyl aminopeptidase (aminopeptidase B), leukotriene A4 hydrolase (a zinc metalloprotease that displays both epoxide hydrolase and aminopeptidase activities), alanyl aminopeptidase (aminopeptidase M/N), leucyl/cystinyl aminopeptidase (oxytocinase/vasopressinase), and membrane dipeptidase (leukotriene D4 hydrolase). It is being studied for use in the treatment of acute myelocytic leukemia. It is derived from Streptomyces olivoreticuli. Ubenimex has been found to inhibit the enzymatic degradation of oxytocin, vasopressin, enkephalins, and various other peptides and compounds. Group: Main Products. Alternative Names: 3-(r)-amino-2-(s)-hydroxy-4-phenylbutanoyl-(s)-leucine;n-(3-amino-2-hydroxy-1-oxo-4-phenylbutyl)-,(s-(r*,s*))-l-leucin;nk421;UBENIMEX;N-[(2S,3R)-3-AMINO-2-HYDROXY-1-OXO-4-PHENYLBUTYL]-L-LEUCINE;N-((2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTYRYL)-L-LEUCINE;[(2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTYRYL]-L-LEUCINE;[(2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTANOYL]-LEU. Grades: 99%. CAS No. 58970-76-6. Product ID: ACM58970766. Molecular formula: C16H24N2O4. Mole weight: 308.37. IUPAC Name: (2S)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoicacid. Appearance: White crystalline powder. EC Number: 261-529-2. Boiling Point: 604.7ºC at 760 mmHg. Melting Point: 245ºC. Flash Point: 319.5ºC. Density: 1.197 g/cm³. |