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| Product | Description | |
|---|---|---|
| Bevacizumab | Bevacizumab, a humanized IgG1 monoclonal antibody, specifically binds to all VEGF-A isoforms with high affinity. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human VEGF, Humanized Antibody. CAS No. 216974-75-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9906. |  |
| Bevacizumab | Bevacizumab Inhibitor. Uses: Scientific use. Product Category: T9904. CAS No. 216974-75-3. |  |
| Bevacizumab | Bevacizumab is an angiogenesis inhibiting monoclonal antibody which is commonly used to treat certain metastatic cancers. It acts via inhibiting vascular endothelial growth factor A (VEGF-A). Uses: For the treatment of certain metastatic cancers. Synonyms: Avastin. Grades: 98% by HPLC. CAS No. 216974-75-3. Molecular formula: C6638H10160N1720O2108S44. Mole weight: 149146.82. |  |
| bevacizumab-awwb | Bevacizumab-awwb is the first anti-cancer biosimilar and the first bevacizumab biosimilar approved for the treatment of five types of cancer, including in combination with chemotherapy for non-squamous non-small cell lung cancer (NSCLC), in combination with chemotherapy for metastatic colorectal cancer (mCRC), in combination with interferon alfa for glioblastoma, metastatic renal cell carcinoma and in combination with chemotherapy for persistent, recurrent, or metastatic carcinoma of the cervix. Uses: The traetment of nsclc, etc. Synonyms: Mvasi. | |
| CysLT1 Antagonist Q8 | CysLT1 antagonist Q8 is a cysteinyl leukotreine (CysLT1) receptor antagonist inhibiting angiogenesis in transgenic fluorescent zebrafish, and human microvascular endothelial cell (HMEC-1) proliferation, tubule formation, and migration. CysLT1 antagonist Q8 exhibits antiangiogenic effect in a VEGF-independent in vitro model of angiogenesis and an additive antiangiogenic response with bevacizumab. Synonyms: Q8 hydrochloride; Q 8 hydrochloride; Q-8 hydrochloride; (E)-2-(2-Quinolin-2-yl-vinyl)-benzene-1,4-diol Hydrochloride. Grades: 99%. CAS No. 1541762-55-3. Molecular formula: C17H14ClNO2. Mole weight: 299.75. | |
| LP-261 | LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest. Screening in the NCI60 cancer cell lines resulted in a mean GI50 of approximately 100 nM. LP-261 is a very potent inhibitor of angiogenesis, preventing microvessel outgrowth in the rat aortic ring assay and HUVEC cell proliferation at nanomolar concentrations. Complete inhibition of tumor growth was achieved in the PC3 xenograft model and shown to be schedule dependent. Excellent inhibition of tumor growth in the SW620 model was observed, comparable with paclitaxel. Combining oral, low dose LP-261 with bevacizumab led to significantly improved tumor inhibition. Oral LP-261 is very effective at inhibiting tumor growth in multiple mouse xenograft models and is well tolerated. Synonyms: LP261; LP 261. Grades: 99%. CAS No. 915412-67-8. Molecular formula: C22H19N3O4S. Mole weight: 421.47. | |
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