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| Product | Description | |
|---|---|---|
| Bexarotene | 4-[1-(5,6,7,8 -tetrahydro- 3,5,5,8,8-pentamethyl -2-naphthalenyl) ethenyl] benzoic acid. CAS No. 153559-49-0. Product ID: 8-01687. Molecular formula: C24H28O2. Mole weight: 348.48. Properties: mp 160-166ºC. |  |
| Bexarotene | Bexarotene. Group: Biochemicals. Alternative Names: 4-[1- (5, 6, 7, 8-Tetrahydro-3, 5, 5, 8, 8-pentamethyl-2-naphthalenyl) ethenyl) benzoic acid; LG 100069; LG 1069. Grades: Highly Purified. CAS No. 153559-49-0. Pack Sizes: 100mg. Molecular Formula: C24H28O2. US Biological Life Sciences. |  Worldwide |
| Bexarotene | Bexarotene is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma. Synonyms: LGD1069; LGD 1069; LGD-1069; LG 100069; Ro 26-445; SR 11247; 3-methyl TTNEB. Bexarotene; US brand name: Targretin. Grades: >98%. CAS No. 153559-49-0. Molecular formula: C24H28O2. Mole weight: 348. |  |
| Bexarotene | Bexarotene (LGD1069) is a high-affinity and selective retinoid X receptors ( RXR ) agonist with EC 50 s of 33, 24, 25 nM for RXRα , RXRβ , and RXRγ , respectively. Bexarotene shows limited affinity for RAR receptors (EC 50 >10000 nM) [1] [2] [3]. Bexarotene can be used for the research of cutaneous T-cell lymphoma. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LGD1069. CAS No. 153559-49-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-14171. |  |
| Bexarotene-13C4 | Used as an antineoplastic. A selective retinoid X receptor (RXR) agonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Bexarotene-13C4 Methyl Ester | Protected Bexarotene. Used as an antineoplastic. Also used in the preparation of bexarotene analogs as RXR selective agonists. Group: Biochemicals. Alternative Names: 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]-benzoic Acid Methyl Ester-13C4; Methyl 4-(1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)-1-ethenyl]benzoate-13C4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Bexarotene (4-(1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoic Acid) | A retinoid X receptor (RXR) agonist that can permeate the blood-brain barrier and rapidly reduce AB40 and AB42 levels in APP/PS1 mice in an ApoE-dependent manner (25% reduction in 6h and 50% reduction in 72h). Causes a rapid reversal of cognitive, social, and olfactory deficts. Shown to progressively enhance the expression of ApoE and ATP-binding cassette transporters ABCA1 and ABCG1. Also stimulates the secretion of highly lapidated HDL particles in primary microglia and astrocytes. Does not affect the levels of AB proteases, insulin degrading enzyme, and neprilysin. Group: Biochemicals. Grades: Highly Purified. CAS No. 153559-49-0. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Bexarotene (4-[1- (5, 6, 7, 8-Tetrahydro-3, 5, 5, 8, 8-pentamethyl-2-naphthalenyl) ethenyl) benzoic Acid, SR-11247, LGD-1069, Targretin) | Used as an antineoplastic. A selective retinoid X receptor (RXR) agonist. Group: Biochemicals. Alternative Names: 4-[1- (5, 6, 7, 8-Tetrahydro-3, 5, 5, 8, 8-pentamethyl-2-naphthalenyl) ethenyl) benzoic Acid, SR-11247, LGD-1069, Targretin. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Bexarotene Acyl Glucuronide | Bexarotene Acyl Glucuronide is a glucuronide metabolite of Bexarotene. Synonyms: Bexarotene Acyl-β-D-glucuronide; 1-[4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentaMethyl-2-naphthalenyl)ethenyl]benzoate] β-D-Glucopyranuronic Acid. Grades: > 95%. CAS No. 198700-33-3. Molecular formula: C30H36O8. Mole weight: 524.62. | |
| Bexarotene Acyl Glucuronide | Bexarotene Acyl Glucuronide. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-((4-(1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoyl)oxy)tetrahydro-2H-pyran-2-carboxylic acid. CAS No. 198700-33-3. Molecular Formula: C30H36O8. Mole Weight: 524.62. Catalog: APB198700333. |  |
| Bexarotene, Free Acid (Targretin, Targretyn, Targrexin, LGD-1069, LG 1069, LG100069, SR-11247) | Bexarotene (LGD-1069) is a synthetic retinoid analog with specific affinity for the retinoid X receptor and belongs to a group of compounds called rexinoids. It is an oral, noncytotoxic drug that was approved in Europe and in the U.S.A. for the treatment of refractory advanced-stage cutaneous T-cell lymphomas (CTCL). Group: Biochemicals. Grades: Highly Purified. CAS No. 153559-49-0. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Bexarotene Impurity 1 | Bexarotene Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-1-yl)vinyl)benzoic acid. Molecular Formula: C24H28O2. Mole Weight: 348.49. Catalog: APB03860. | |
| Bexarotene Impurity 1 | Bexarotene Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 142-30-3. Molecular Formula: C8H14O2. Mole Weight: 142.2. Catalog: APB142303. | |
| Bexarotene Impurity 10 | Bexarotene Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(1-(3-ethyl-1,1,3,6-tetramethyl-2,3-dihydro-1H-inden-5-yl)vinyl)benzoic acid. Molecular Formula: C24H28O2. Mole Weight: 348.49. Catalog: APB03858. | |
| Bexarotene Impurity 10 | Bexarotene Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1349659-51-3. Molecular Formula: C38H46O2. Mole Weight: 534.78. Catalog: APB1349659513. | |
| Bexarotene Impurity 13 | Bexarotene Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C48H56O4. Mole Weight: 696.97. Catalog: APB12307. | |
| Bexarotene Impurity 16 | Bexarotene Impurity 16. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-1-yl)vinyl)benzoic acid. Molecular Formula: C24H28O2. Mole Weight: 348.49. Catalog: APB03852. | |
| Bexarotene Impurity 17 | Bexarotene Impurity 17. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-1-yl)vinyl)benzoic acid. Molecular Formula: C24H28O2. Mole Weight: 348.49. Catalog: APB03853. | |
| Bexarotene Impurity 2 | Bexarotene Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(1-(2,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-1-yl)vinyl)benzoic acid. Molecular Formula: C24H28O2. Mole Weight: 348.49. Catalog: APB03861. | |
| Bexarotene Impurity 2 | Bexarotene Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 6117-86-8. Molecular Formula: C8H16O2. Mole Weight: 144.21. Catalog: APB6117868. | |
| Bexarotene Impurity 3 | Bexarotene Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 4-(1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoate. CAS No. 153559-48-9. Molecular Formula: C25H30O2. Mole Weight: 362.51. Catalog: APB153559489. | |
| Bexarotene Impurity 3 | Bexarotene Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H23Cl. Mole Weight: 238.8. Catalog: APB12308. | |
| Bexarotene Impurity 4 | Bexarotene Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 4-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalene-2-carbonyl)benzoate. CAS No. 153559-45-6. Molecular Formula: C24H28O3. Mole Weight: 364.49. Catalog: APB153559456. | |
| Bexarotene Impurity 5 | Bexarotene Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4,4'-(1,2-bis(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclobutane-1,2-diyl)dibenzoic acid. Molecular Formula: C48H56O4. Mole Weight: 696.97. Catalog: APB03859. | |
| Bexarotene Impurity 6 | Bexarotene Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-ethyl-1,3,3,5-tetramethyl-2,3-dihydro-1H-indene. CAS No. 29641-87-0. Molecular Formula: C15H22. Mole Weight: 202.34. Catalog: APB29641870. | |
| Bexarotene Impurity 6 | Bexarotene Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H24O. Mole Weight: 220.36. Catalog: APB12296. | |
| Bexarotene Impurity 7 | Bexarotene Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1,4-bis(1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzene. CAS No. 1349659-57-9. Molecular Formula: C40H50. Mole Weight: 530.84. Catalog: APB1349659579. | |
| Bexarotene Impurity 7 | Bexarotene Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C24H28O3. Mole Weight: 364.49. Catalog: APB12306. | |
| Bexarotene Impurity 8 | Bexarotene Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1,1,4,4,6-pentamethyl-7-(1-(4-(prop-1-en-2-yl)phenyl)vinyl)-1,2,3,4-tetrahydronaphthalene. CAS No. 1349659-55-7. Molecular Formula: C26H32. Mole Weight: 344.54. Catalog: APB1349659557. | |
| Bexarotene Impurity 9 | Bexarotene Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzamide. Molecular Formula: C24H29NO. Mole Weight: 347.50. Catalog: APB03857. | |
| Bexarotene (Targretin, Targretyn, Targrexin, LGD-1069, LG 1069, LG100069, SR-11247) | Bexarotene (also called Targretin, Targretyn, Targrexin, LGD-1069, LG 1069, LG100069, SR-11247) is a synthetic retinoid analog with specific affinity for the retinoid X receptor and belongs to a group of compounds called rexinoids. It is an oral, noncytotoxic drug that was approved in Europe and in the U.S.A. for the treatment of refractory advanced-stage cutaneous T-cell lymphomas. The receptor-selective retinoids might be particularly useful in preventing ER-negative breast cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 153559-49-0. Pack Sizes: 5mg. Molecular Formula:C24H28O2 MOLECULAR WEIGHT: 348.48. US Biological Life Sciences. | Worldwide |
| 6-Hydroxy bexarotene | 6-Hydroxy bexarotene. Group: Biochemicals. Alternative Names: 4-[1- (5, 6, 7, 8-Tetrahydro-6-hydroxy-3, 5, 5, 8, 8-pentamethyl-2-naphthalenyl) ethenyl]benzoic acid. Grades: Highly Purified. CAS No. 368451-07-4. Pack Sizes: 100mg, 250mg. Molecular Formula: C24H28O3. US Biological Life Sciences. | Worldwide |
| 6-Hydroxy Bexarotene | 6-Hydroxy Bexarotene is a metabolite of Bexarotene. Synonyms: 4-[1-(5,6,7,8-Tetrahydro-6-hydroxy-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic Acid. Grades: > 95%. CAS No. 368451-07-4. Molecular formula: C24H28O3. Mole weight: 364.49. | |
| 6-Hydroxy Bexarotene | 6-Hydroxy Bexarotene. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(1-(6-hydroxy-3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoic acid. Molecular Formula: C24H28O3. Mole Weight: 364.49. Catalog: APB03856. | |
| 6-oxo-Bexarotene | 6-Oxo Bexarotene is a metabolite of Bexarotene. Synonyms: 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-6-oxo-2-naphthalenyl)ethenyl]-benzoic Acid; 6-Keto Bexarotene. Grades: > 95%. CAS No. 368451-13-2. Molecular formula: C24H26O3. Mole weight: 362.47. | |
| 6-oxo-Bexarotene | 6-oxo-Bexarotene. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(1-(3,5,5,8,8-pentamethyl-6-oxo-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoic acid. Molecular Formula: C24H26O3. Mole Weight: 362.47. Catalog: APB03854. | |
| 6-Oxo Bexarotene | 6-Oxo Bexarotene. Group: Biochemicals. Grades: Highly Purified. CAS No. 368451-13-2. Pack Sizes: 100mg, 250mg. Molecular Formula: C24H26O3. US Biological Life Sciences. | Worldwide |
| 7-Hydroxy bexarotene | 7-Hydroxy bexarotene. Group: Biochemicals. Alternative Names: 4-[1- (5, 6, 7, 8-Tetrahydro-7-hydroxy-3, 5, 5, 8, 8-pentamethyl-2-naphthalenyl) ethenyl]benzoic acid. Grades: Highly Purified. CAS No. 368451-10-9. Pack Sizes: 50mg, 100mg. Molecular Formula: C24H28O3. US Biological Life Sciences. | Worldwide |
| 7-Hydroxy Bexarotene | 7-Hydroxy Bexarotene is a metabolite of Bexarotene. Synonyms: 4-[1-(5,6,7,8-Tetrahydro-7-hydroxy-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic Acid. Grades: > 95%. CAS No. 368451-10-9. Molecular formula: C24H28O3. Mole weight: 364.49. | |
| 7-Hydroxy Bexarotene | 7-Hydroxy Bexarotene. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(1-(7-hydroxy-3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoic acid. Molecular Formula: C24H28O3. Mole Weight: 364.49. Catalog: APB03855. | |
| 7-oxo-Bexarotene | 7-Oxo Bexarotene is a metabolite of Bexarotene. Synonyms: 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-7-oxo-2-naphthalenyl)ethenyl]-benzoic Acid; 7-Keto Bexarotene. Grades: > 95%. CAS No. 368451-15-4. Molecular formula: C24H26O3. Mole weight: 362.47. | |
| 7-Oxo Bexarotene | 7-Oxo Bexarotene. Group: Biochemicals. Grades: Highly Purified. CAS No. 368451-15-4. Pack Sizes: 100mg, 250mg. Molecular Formula: C24H26O3. US Biological Life Sciences. | Worldwide |
| 7-Oxo Bexarotene | 7-Oxo Bexarotene. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(1-(3,5,5,8,8-pentamethyl-7-oxo-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoic acid. CAS No. 368451-15-4. Molecular Formula: C24H26O3. Mole Weight: 362.47. Catalog: APB368451154. | |
| Desmethylene Oxo-bexarotene Methyl Ester | A possible drug candidate in the treatment of cancers. Intermediate in the preparation of tetramethylcyclohexane derivatives as retinoid X receptors modulators. Group: Biochemicals. Alternative Names: Methyl 4-[ (5, 6, 7, 8-Tetrahydro-3, 5, 5, 8, 8-pentamethyl-2-naphthalenyl) carbonyl]benzoate; 4-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]-benzoic Acid Methyl Ester. Grades: Highly Purified. CAS No. 153559-45-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Oxo-bexarotene Methyl Ester | Oxo-bexarotene Methyl Ester. Group: Biochemicals. Alternative Names: Methyl 4-[ (5, 6, 7, 8-tetrahydro-3, 5, 5, 8, 8-pentamethyl-2-naphthalenyl) carbonyl]benzoate. Grades: Highly Purified. CAS No. 153559-45-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C24H28O3. US Biological Life Sciences. | Worldwide |
| 1- (4- (1- (3, 5, 5, 8, 8-Pentamethyl-5, 6, 7, 8-tetrahydronaphthalen-2-yl) vinyl) phenyl) ethanone | 1- (4- (1- (3, 5, 5, 8, 8-Pentamethyl-5, 6, 7, 8-tetrahydronaphthalen-2-yl) vinyl) phenyl) ethanone is used for the synthesis of bexarotene. Group: Biochemicals. Grades: Highly Purified. CAS No. 1349659-53-5. Pack Sizes: 10mg, 50mg. Molecular Formula: C25H30O, Molecular Weight: 346.51. US Biological Life Sciences. | Worldwide |
| 2,2,5,5-Tetramethyloxolan-3-one | 2,2,5,5-Tetramethyloxolan-3-one is a reagent that is used in the synthesis of 6-Hydroxy Bexarotene (H817500), which is a metabolite of Bexarotene (B336750). Group: Biochemicals. Grades: Highly Purified. CAS No. 5455-94-7. Pack Sizes: 250mg, 1g. Molecular Formula: C8H14O2. US Biological Life Sciences. | Worldwide |
| CD1530 | CD1530 is a potent and selective retinoic acid receptor(RAR) agonist with Ki values of 150, 1500 and 2750 nM for RARγ, RARβ and RARα receptors respectively. It was also a potent CYP26A1 inhibitor as ketoconazole with an IC50 value of 530 nM. It inhibited excessive ROS production in tongue epithelial cells in vitro. It demonstrates transcriptional activity at RARγ with an AC50 value of 1.8 nM. It has been shown to preserve human tendon stem cell characteristics, promote repair of injured skeletal muscle, and in combination with bexarotene to inhibit oral carcinogenesis. Synonyms: 4-(6-Hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoic acid; CD 1530; CD-1530; Benzoic acid, 4-(6-hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)-; 4-[7-(Adamantan-1-yl)-6-hydroxy-2-naphthyl]benzoic acid. Grades: ≥95%. CAS No. 107430-66-0. Molecular formula: C27H26O3. Mole weight: 398.49. | |
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