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| Product | Description | |
|---|---|---|
| Bicuculline | Bicuculline ((+)-Bicuculline) is A competing neurotransmitter GABA A receptor antagonist ( IC 50 =2 μM). Bicuculline also blocks Ca 2+ activating potassium (SK) channels and subsequently blocks slow post-hyperpolarization (slow AHP). Bicuculline has anticonvulsant activity. Bicuculline can be used to induce seizures in mice [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Bicuculline; d-Bicuculline. CAS No. 485-49-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N0219. |  |
| Bicuculline, 98+% (GABAA Receptor Antagonist, (+)-Bicuculline) | A potent allosteric antagonist of vertebrate GABAA receptors. Blocks GABAA-induced chloride currents in cultured neurons (IC50 = 740nM). Shown to increase blood pressure in spontaneously hypertensive rats and cause convulsion in experimental animals. Also, increases the amplitude of spontaneous colonic contractions. Group: Biochemicals. Alternative Names: (6R)-6-[(5S)-5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]lisoquinolin-5-yl]furo[3,4-e]-1,3-benzodioxol-8(6H)-one; (+)-Bicuculline; d-Bicuculline; NSC 32192. Grades: Highly Purified. CAS No. 485-49-4. Pack Sizes: 100mg, 250mg. Molecular Formula: C??H??NO?, Molecular Weight: 367.35. US Biological Life Sciences. |  Worldwide |
| Bicuculline, 99+% (GABAA Receptor Antagonist, (+)-Bicuculline) | A potent allosteric antagonist of vertebrate GABAA receptors. Blocks GABAA-induced chloride currents in cultured neurons (IC50 = 740nM). Shown to increase blood pressure in spontaneously hypertensive rats and cause convulsion in experimental animals. Also, increases the amplitude of spontaneous colonic contractions. Group: Biochemicals. Alternative Names: (6R)-6-[(5S)-5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]lisoquinolin-5-yl]furo[3,4-e]-1,3-benzodioxol-8(6H)-one; (+)-Bicuculline; d-Bicuculline; NSC 32192. Grades: Highly Purified. CAS No. 485-49-4. Pack Sizes: 50mg. Molecular Formula: C??H??NO?, Molecular Weight: 367.35. US Biological Life Sciences. | Worldwide |
| Bicuculline (GABAA Receptor Antagonist, (+)-Bicuculline) | Bicuculline (GABAA Receptor Antagonist, (+)-Bicuculline). Group: Biochemicals. Alternative Names: (6R)-6-[(5S)-5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]lisoquinolin-5-yl]furo[3,4-e]-1,3-benzodioxol-8(6H)-one; (+)-Bicuculline; d-Bicuculline; NSC 32192. Grades: Plant Grade. CAS No. 485-49-4. Pack Sizes: 20mg. Molecular Formula: C20H17NO6, Molecular Weight: 367.351999999999. US Biological Life Sciences. | Worldwide |
| Bicuculline methiodide | Bicuculline methiodide is a potent GABA(A) receptors blocker. Bicuculline methiodide alters membrane properties and firing pattern. Bicuculline methiodide reduces the Apamin-sensitive afterhyperpolarization, while Apamin is a toxin isolated from bee venom to block small conductance Ca 2+ -activated K + channels. Bicuculline methiodide facilitates burst firing via blocking apamin-sensitive Ca 2+ -activated K + current [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-Bicuculline methiodide; l-Bicuculline methiodide. CAS No. 40709-69-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103474. | |
| Bicuculline Methiodide | GABA receptor antagonist. Group: Biochemicals. Alternative Names: (5R)-5-[(6S)-6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl]-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium Iodide; (-)-Bicuculline Methiodide. Grades: Highly Purified. CAS No. 55950-07-7. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Bicuculline methochloride | Bicuculline ((+)-Bicuculline; d-Bicuculline) methochloride is a selective GABAA receptor antagonist with an IC 50 value of 3 μM. Bicuculline methochloride induces clonic tonic convulsions in mammals and can also be used to block Ca 2+ activated potassium channels. Bicuculline methochloride can be used in studies of epilepsy and other related psychiatric disorders [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-Bicuculline methochloride; l-Bicuculline methochloride. CAS No. 38641-83-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137790. | |
| +)-Bicuculline | 100mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C20H17NO6. CAS No. 485-49-4. Prepack ID 44241417-100mg. Molecular Weight 367.35. See USA prepack pricing. |  |
| (-)-Bicuculline methiodide | (-)-Bicuculline methiodide. Group: Biochemicals. Grades: Purified. CAS No. 40709-69-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| (-)-Bicuculline methiodide | (-)-Bicuculline methiodide is the methiodide salt of (+)-bicuculline, which is a potent antagonist of GABAA receptors. Synonyms: [R-(R,S)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium iodide. Grades: ≥99% by HPLC. CAS No. 40709-69-1. Molecular formula: C21H20INO6. Mole weight: 509.3. |  |
| (-)-Bicuculline methobromide | (-)-Bicuculline methobromide. Group: Biochemicals. Grades: Purified. CAS No. 73604-30-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| (-)-Bicuculline methobromide | (-)-Bicuculline methobromide is the methobromide salt of (+)-bicuculline, which is a potent antagonist of GABAA receptors. Synonyms: [R-(R,S)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium bromide. Grades: ≥98% by HPLC. CAS No. 73604-30-5. Molecular formula: C21H20BrNO6. Mole weight: 462.3. | |
| (-)-Bicuculline methobromide | (-)-Bicuculline methobromide (l-Bicuculline methobromide) is a potent GABA A receptor antagonist. (-)-Bicuculline methobromide blocks afterhyperpolarizations (AHPs) mediated by Ca 2+ -activated K + channels in various types of neurons [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: l-Bicuculline methobromide. CAS No. 73604-30-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-100783. | |
| (-)-Bicuculline methochloride | (-)-Bicuculline methochloride is the methochloride salt of (+)-bicuculline, which is a potent antagonist of GABAA receptors. Synonyms: [R-(R,S)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium chloride. Grades: ≥99% by HPLC. CAS No. 53552-05-9. Molecular formula: C21H20ClNO6. Mole weight: 417.85. | |
| (-)-Bicuculline Methochloride | Water-soluble GABAA antagonist. Methochloride salt of (+)-bicuculline. Water soluble and more stable than bicuculline. Non-GABA receptor-mediated actions reported. Group: Biochemicals. Alternative Names: [R-(R*,S*)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium chloride. Grades: Highly Purified. CAS No. 53552-05-9. Pack Sizes: 10mg, 50mg. Molecular Formula: C??H??ClNO?, Molecular Weight: 417.85. US Biological Life Sciences. | Worldwide |
| Phaclofen | Phaclofen is a selective GABA B receptor antagonist. Phaclofen is a peripheral and central baclofen antagonist. Phaclofen maybe a potential compound in determining the physiological significance of central and peripheral bicuculline-insensitive receptors with which GABA and (-)-baclofen interact [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 114012-12-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-100798. | |
| SR 95531 hydrobromide | SR 95531 hydrobromide is a competitive GABAA receptor antagonist. SR 95531 differs from bicuculline that it selectively antagonizes GABA-induced Cl- currents but exhibits little action on pentobarbitone-induced currents. SR 95531 also acts as a low affinity glycine receptor antagonist. Uses: Gaba antagonists. Synonyms: SR 95531 hydrobromide; SR95531 hydrobromide; SR-95531 hydrobromide; 4-[6-imino-3-(4-methoxyphenyl)pyridazin-1-yl]butanoic acid hydrobromide; 6-Imino-3-(4-methoxyphenyl)-1(6H)-pyridazinebutanoic acid hydrobromide; Gabazine hydrobromide. Grades: ≥98% by HPLC. CAS No. 104104-50-9. Molecular formula: C15H17N3O3.HBr. Mole weight: 368.23. | |
| Yangonin | Extract from Piper methysticum, enhancing the binding of bicuculline at the γ-amino butyric acid. Uses: Enhances the binding of bicuculline. Synonyms: 4-methoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]pyran-2-one; 4-methoxy-6-(beta-(p-anisyl)vinyl)-alpha-pyrone. Grades: ≥98%. CAS No. 500-62-9. Molecular formula: C15H14O4. Mole weight: 258.27. | |
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