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Bilobalide, a sesquiterpene trilactone constituent of Ginkgo biloba , inhibits the NMDA-induced efflux of choline with an IC 50 value of 2.3 μM. Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells. Exerts protective and trophic effects on neurons [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Bilobalide. CAS No. 33570-04-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0076.
Bilobalide
Bilobalide, a sesquiterpene trilactone constituent of Ginkgo biloba, inhibits the NMDA-induced efflux of choline with an IC50 value of 2.3 μM. Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells. Exerts protective and trophic effects on neurons. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (-)-Bilobalide. Product Category: Inhibitors. CAS No. 33570-04-6. Molecular formula: C15H18O8. Mole weight: 326.3. Purity: 0.98. Canonical SMILES: CC(C)(C)[C@@]1(C[C@H]2[C@@]3([C@]14[C@H](C(=O)O[C@H]4OC3=O)O)CC(=O)O2)O. Product ID: ACM33570046. Alfa Chemistry ISO 9001:2015 Certified.
Bilobalide
Bilobalide is a biologically active terpenic trilactone present in Ginkgo biloba. Synonyms: (-)-Bilobalide; Vitexicarpim; (3aS,5aR,8aS)-9R-(1,1-dimethylethyl)-10,10aS-dihydro-8R,9-dihydroxy-4H,5aH,9H-furo[2,3-b]furo[3',2':2,3]cyclopenta[1,2-c]furan-2,4,7(3H,8H)-trione. Grade: >98%. CAS No. 33570-04-6. Molecular formula: C15H18O8. Mole weight: 326.30.
Bilobalide
Neuroprotective. Mitochondrial gene expression regulator. ROS scavenger. Competitive GABA(A) receptor antagonist. Apoptosis inhibitor. CREB phosphorylation enhancer. Stimulates neurogenesis and synaptogenesis. Hepatic cytochrome P450 inducer. Activates the phosphatidylinositol 3-kinase (PI3K) dependent pathway. Group: Biochemicals. Grades: Highly Purified. CAS No. 33570-04-6. Pack Sizes: 10mg, 50mg. Molecular Formula: C15H18O8. US Biological Life Sciences.
Bilobalide A. Group: Biochemicals. Grades: Plant Grade. CAS No. 33570-04-6. Pack Sizes: 20mg. Molecular Formula: C15H18O8, Molecular Weight: 326.3. US Biological Life Sciences.
Worldwide
(?)-Bilobalide
analytical standard. Group: Natural compounds.
Ginkgolide A
Ginkgolide A is an extract from in Ginkgo biloba and a g-aminobutyric acid (GABA) antagonist with a Ki of 14.5 μM. Synonyms: (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11aS)-3-(1,1-Dimethylethyl)hexahydro-4,7b-dihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione; 9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione, 3-(1,1-dimethylethyl)hexahydro-4,7b-dihydroxy-8-methyl-, [1R-(1α,3β,3aS*,4β,6aα,7aα,7bα,8α,10aα,11aS*)]-; [1R-(1α,3β,3aS*,4β,6aα,7aα,7bα,8α,10aα,11aS*)]-3-(1,1-Dimethylethyl)hexahydro-4,7b-dihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione; Bilobalide A; BN 52020. Grade: >98%. CAS No. 15291-75-5. Molecular formula: C20H24O9. Mole weight: 408.40.
Ginkgolide B
Ginkgolide B is a PAFR antagonist with an IC50 of 3.6 μM. Ginkgolide B is a bioactive diterpenoid trilactone derived from Ginkgo biloba leaves, known for its potent platelet-activating factor (PAF) antagonism. It has a complex structure with multiple chiral centers and exhibits significant neuroprotective and cerebrovascular benefits. These properties make it a promising candidate for treating neurodegenerative diseases, inflammation, and conditions related to cerebral blood flow. Uses: Fibrinolytic agents. Synonyms: (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)-3-(1,1-Dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione; 5H-Dicyclopenta[b,c]furan-3,5a(6H)-diacetic acid, 6-tert-butyl-3a-carboxyhexahydro-α5a,1,2,3,5,8-hexahydroxy-α3-methyl-, tri-γ-lactone; Ginkgolide A, 1-hydroxy-, (1β)-; 9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione, 3-(1,1-dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-, [1R-(1α,3β,3aS*,4β,6aα,7aα,7bα,8α,10aα,11β,11aR*)]-; Bilobalide B; BN 52021; BN 52051; Ginkgolides, ginkgolide B. Grade: >98%. CAS No. 15291-77-7. Molecular formula: C20H24O10. Mole weight: 424.40.
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