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| Product | Description | |
|---|---|---|
| Bimatoprost Acid | Bimatoprost Acid is an impurity of the antiglaucoma agent Bimatoprost. It is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenoic Acid; 17-Phenyl-18,19,20-trinor-PGF2α; PhXA 70; (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-5-heptenoic Aci. Grades: > 95%. CAS No. 38344-08-0. Molecular formula: C23H32O5. Mole weight: 388.51. |  |
| Bimatoprost Acid Methyl Ester | Bimatoprost Acid Methyl Ester is an impurity of the antiglaucoma agent Bimatoprost. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenoic Acid Methyl Ester; 17-Phenyl-18,19,20-trinor-PGF2α Methyl Ester. Grades: > 95%. CAS No. 38315-47-8. Molecular formula: C24H34O5. Mole weight: 402.54. | |
| (15R)-Bimatoprost Acid | (15R)-Bimatoprost Acid is an impurity of the antiglaucoma agent Bimatoprost (B386820). (15R)-Bimatoprost Acid is a metabolically stable analog of PGF2α (P838625) and is a potent agonist for the FP receptor. Group: Biochemicals. Grades: Highly Purified. CAS No. 41639-71-8. Pack Sizes: 1mg, 10mg. Molecular Formula: C23H32O5, Molecular Weight: 388.5. US Biological Life Sciences. |  Worldwide |
| (15R)-Bimatoprost Acid-d4 | (15R)-Bimatoprost Acid-d4 is the isotope labelled analog of (15R)-Bimatoprost Acid (B386830); an impurity of the antiglaucoma agent Bimatoprost (B386820). (15R)-Bimatoprost Acid is a metabolically stable analog of PGF2α (P838625) and is a potent agonist for the FP receptor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C23H28D4O5, Molecular Weight: 392.52. US Biological Life Sciences. | Worldwide |
| 15(R)-17-Phenyl trinor prostaglandin F2α | 15(R)-17-Phenyl trinor prostaglandin F2α is an impurity of the antiglaucoma agent Bimatoprost. It is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor. Synonyms: 15-epi Bimatoprost; 15(R)-Bimatoprost; 15(R)-17-phenyl trinor PGF2α; (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoic acid. Grades: ≥98%. CAS No. 41639-71-8. Molecular formula: C23H32O5. Mole weight: 388.5. | |
| 15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester | 15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 value for the free acid forms of 15(R)-17-phenyl trinor PGF2α wa determined to be 30 nM in a FP receptor binding assay using the cat iris sphincter muscle. Synonyms: 9α,11α,15R-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-oic acid, isopropyl ester; 15-epi Bimatoprost isopropylester; 15(R)-Bimatoprost isopropyl ester; 15(R)-17-phenyl trinor PGF2α isopropyl ester; Isopropyl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl}-5-heptenoate; 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-, 1-methylethyl ester, (5Z)-. Grades: 98%. CAS No. 130273-87-9. Molecular formula: C26H38O5. Mole weight: 430.59. | |
| 17-Phenyl trinor PGF2α isopropyl ester | 17-phenyl trinor PGF2α N-ethyl amide is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost.1 The N-ethyl amide prostaglandin prodrugs are converted to the active free acid more slowly than the analogous prostaglandin ester prodrugs such as latanoprost.2 This product is the isopropyl ester of the free acid prostaglandin which corresponds to Bimatoprost. The free acid, 17-phenyl trinor PGF2α, is a potent FP receptor agonist.3 In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity. The 17-phenyl trinor PGF2α isopropyl ester derivative is examined for IOP-lowering activity during the development of latanoprost.4 At the dose of 3 μg/eye in the monkey, 17-phenyl trinor PGF2α isopropyl ester is the most potent analog tested in reducing IOP, lowering the IOP 1.3 mm Hg below the level achieved by latanoprost. However, this derivative is also significantly more irritating to the eye than latanoprost. Uses: Scientific research. Group: Signaling pathways. CAS No. 130209-76-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116161A. |  |
| 5-Heptenoic acid,7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-,1-methylethyl ester,(5Z)- | 5-Heptenoic acid,7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-,1-methylethyl ester,(5Z)-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 15(R)-17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA ISOPROPYL ESTER;9ALPHA,11ALPHA,15R-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER. Product Category: Heterocyclic Organic Compound. CAS No. 130273-87-9. Molecular formula: C26H38O5. Mole weight: 430.58. Product ID: ACM130273879. Alfa Chemistry ISO 9001:2015 Certified. Categories: Bimatoprost isopropyl ester. |  |
| Dimethyl (2-Oxo-4-phenylbutyl)phosphonate | Dimethyl (2-Oxo-4-phenylbutyl)phosphonate is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Synonyms: (2-Oxo-4-phenylbutyl)phosphonic Acid Dimethyl Ester; Bimatoprost Impurity 12; Phosphonic acid, (2-oxo-4-phenylbutyl)-, dimethyl ester. Grades: > 98%. CAS No. 41162-19-0. Molecular formula: C12H17O4P. Mole weight: 256.23. | |
| N-Cyclohexyl-desmethyl Bimatoprost | N-Cyclohexyl-desmethyl Bimatoprost is the derivative of Bimatoprost Acid Methyl Ester (B386825). Impurity of Drug. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C29H43NO4, Molecular Weight: 469.66. US Biological Life Sciences. | Worldwide |
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