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| Product | Description | |
|---|---|---|
| Bio-Clean for septic tanks | Bio-Clean is the safest way to keep your septic system running as is it non-poisonous! Bio-Clean changes the waste particles into water, carbon dioxide and mineral ash which run harmlessly out of your waste system. These elements are then available for plant life. Bio-Clean is a blend of natural bacteria and enzymes. Uses: Floor Drains, Bathtubs, Grease Traps. Pack Sizes: 2 Lb Container, 25 Lb Pail. |  USA |
| 1- (2, 6-Dichlorophenyl) piperazine-d8 Hydrochloride | 1- (2, 6-Dichlorophenyl) piperazine-d8 Hydrochloride is the isotope analog of 1- (2, 6-Dichlorophenyl) piperazine Hydrochloride. 1- (2, 6-Dichlorophenyl) piperazine Hydrochloride is used in the preparation of pyrazolopyrimidones and pyrazolopyridones as tankyrase inhibitors which are useful in the treatment of cancer. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C10H5D8Cl3N2, Molecular Weight: 275.63. US Biological Life Sciences. |  Worldwide |
| 1- (2, 6-Dichlorophenyl) piperazine Hydrochloride | 1- (2, 6-Dichlorophenyl) piperazine Hydrochloride is used in the preparation of pyrazolopyrimidones and pyrazolopyridones as tankyrase inhibitors which are useful in the treatment of cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 1507372-81-7. Pack Sizes: 500mg, 5g. Molecular Formula: C10H13Cl3N2, Molecular Weight: 267.58. US Biological Life Sciences. | Worldwide |
| 2-[4-(1-Methylethyl)phenyl4H-1-benzopyran-4-one | 2-[4-(1-Methylethyl)phenyl4H-1-benzopyran-4-one is a potent and selective tankyrase (TNKS) inhibitor affecting cell proliferation with potential treatment for cancers. Flavonoid compound with anti-cancer/ anti-bacterial properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 92831-11-3. Pack Sizes: 1mg, 5mg. Molecular Formula: C18H16O2, Molecular Weight: 264.32. US Biological Life Sciences. | Worldwide |
| Amlexanox | Antiallergic. Anti-inflammatory. Antagonizes the angiogenic and mitogenic activity of FGF-1 through S100A13. Inhibits FGF-1 release. Binds to HSP90. Inhibits C-terminal chaperone activity. Induces an increase in nonsense-containing mRNAs amount in treated cells, leading to the synthesis of functional full-length proteins in an efficient manner. Selective inhibitor of TANK-binding Kinase 1 (TBK1) and IKKepsilon. Reversibly lowers weight and improves insulin sensitivity and reduces inflammation and attenuated hepatic steatosis in obese mices without affecting food intake. Group: Biochemicals. Alternative Names: 2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic Acid; Amoxanox; AA-673; CHX-3673; Aphthasol; Elics; Solfa. Grades: Highly Purified. CAS No. 68302-57-8. Pack Sizes: 25mg, 100mg, 500mg. Molecular Formula: C16H14N2O4, Molecular Weight: 298.29. US Biological Life Sciences. | Worldwide |
| Bromothymol Blue, Sodium Salt, ACS (Dibromothymolsulfone phthalein, BTB) | Bromothymol blue (alt: dibromothymolsulfoneph thalein, bromthymol blue, BTB) is a chemical indicator for weak acids and bases. The bromothymol blue acts as a weak acid in solution and therefore can be in acid or base forms which appear yellow and blue respectively. It is green in neutral solution. Bromothymol blue is typically sold in solid form as the sodium salt of the acid indicator. It also finds occasional use in the laboratory as a biological slide stain. At this point it is already blue, and a drop or two is used on a water slide. The coverslip is placed ontop of the water droplet and the specimen in it, with the blue coloring mixed in. It is sometimes used to define cell walls or nuclei under the microscope.Bromothymol blue is mostly used in measuring substances that would have relatively low acidic or basic levels (near a neutral pH). It's often used in pools, fish tanks, or measuring the presence of carbonic acid in a liquid. Group: Biochemicals. Alternative Names: 3', 3''-Dibromothymolsulfoneph thalein sodium salt; BTB. Grades: ACS Grade. CAS No. 34722-90-2. Pack Sizes: 25g, 100g, 250g. Molecular Formula: C27H27Br2O5SNa, Molecular Weight: 646.36. US Biological Life Sciences. | Worldwide |
| G007-LK | G007-LK is a potent, "rule of 5" compliant and a metabolically stable TNKS1/2 inhibitor. G007-LK displayed high selectivity toward tankyrases 1 and 2 with biochemical IC50 values of 46 nM and 25 nM, respectively, and a cellular IC50 value of 50 nM combined with an excellent pharmacokinetic profile in mice. G007-LK was first discovered by Dr. Stefan Krauss's team. Synonyms: G007LK; G007LK; G007 LK. Grades: >98%. CAS No. 1380672-07-0. Molecular formula: C25H16ClN7O3S. Mole weight: 529.96. |  |
| IWR-1 (IWR-1-endo) | Potent and reversible cell permeable Wnt pathway signaling inhibitor. Inhibits Wnt-induced accumulation of β-catenin, leading to proteasomal degradation of this protein through a destruction complex which consists of Apc, Axin2, CK1 and GSK-3 β. Stabilizes the destruction complex, increasing the level of Axin2 protein without changing the levels of Apc or GSK-3 β. Tankyrase-1 (TNKS1/PARP5a) and Tankyrase-2 (TNKS2/PARP5b) inhibitor (in vitro auto-PARsylation assay). Group: Biochemicals. Alternative Names: 4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide. Grades: Highly Purified. CAS No. 1127442-82-3. Pack Sizes: 5mg, 25mg. Molecular Formula: C??H??N?O?, Molecular Weight: 409.4. US Biological Life Sciences. | Worldwide |
| N-[3- (Trimethoxysilyl) Propyl]Ethylenediamine | 3- (2-Aminoethylamino) propyl]trimethoxysilane is a chemical reagent used in organometallic reactions and the process of signal amplification in biomolecular labelling. Uses: It is mainly used to couple organic polymer and inorganic materials in order to improve the mechanical properties, electrical properties, water resistance, aging resistance, etc.this product can improve the performance of the resin laminate of the epoxy, phenolic, melamine, furan, etc. it is also effective to polypropylene, polyethylene, polypropylene of vinegar, silicone, polyamide, polycarbonate and polyvinyl cyanide. Group: Saltself-assembly materials. Alternative Names: N-(3-trimethoxysilylpropyl)ethane-1,2-diamine; 3- (2-Aminoethylamino) propyltrimethoxysilane; N1-(3-(Trimethoxysilyl)propyl)ethane-1,2-diamine; 1,2-Ethanediamine, N-[3-(trimethoxysilyl)propyl]-; N-(2-Aminoethyl)-3-aminopropyltrimethoxysilane. CAS No. 1760-24-3. Pack Sizes: N-[3- (Trimethoxysilyl) propyl]ethylenediamin (A-1120, KBM-603, OFS-6020, DAMO) is packed in 25KG/200KG drum, IBC tank or ISO tank. It is sealed and stored in cool and well ventilated place away from fire and water. Product ID: N'-(3-trimethoxysilylpropyl)ethane-1,2-diamine. Molecular formula: 222.36. Mole weight: C8H22N2O3Si. CO[Si](CCCNCCN)(OC)OC. InChI=1S/C8H22N2O3Si/c1-11-14(12-2, 13-3)8-4-6-10-7-5-9/h10H, 4-9H2, 1-3H3. PHQOGHDTIVQXHL-UHFFFAOYSA-N. |  |
| Neutral Cellulase for Textile | It is a kind of bio-polishing enzyme for color retention. As the latest product of neutral bio-polishing enzyme, the effect of color retention is advanced. The dosage of this product is 1.0-2.0 %(o.w.f), and the processing time is 30-60 minutes. The bach ratio is 5-15 L/kg(fabric). Applications: It is used for bio-polishing of fiber fabrics, the latest fishing process. it is suitable for woven fabric or knitted fabric.after the treatment of this product, the quality of fabric will improved:(1) reduce fuzz and pilling;(2) good color retention, less color fading;(3) with bright color and glossy;(4) less strength loss, keep tear resistance. Group: Enzymes. Synonyms: endo-1,4-β-D-glucanase; β-1,4-glucanase; β-1,4-endoglucan hydrolase; celluase A; cellulosin AP; endoglucanase D; alkali cellulase; cellulase A 3; celludextrinase; 9.5 cellulase; avicelase; pance. Enzyme Commission Number: EC 3.2.1.4. CAS No. 9012-54-8. Cellulase. Storage: Avoid long-term storage in a place above 30 °C. endo-1,4-β-D-glucanase; β-1,4-glucanase; β-1,4-endoglucan hydrolase; celluase A; cellulosin AP; endoglucanase D; alkali cellulase; cellulase A 3; celludextrinase; 9.5 cellulase; avicelase; pancellase SS; 1,4-(1,3; 1,4)-β-D-glucan 4-glucanohydrolase; EC 3.2.1.4. Pack: 25 kg/drum, 200 kg/drum, IBC tank or as per requirement. Cat No: NATE-1750. |  |
| Nonidet-P40 substitute (NP40, NP-40, Igepal CA-630, T-DET O-series, ethoxylated octylphenol, T-DET O-9) | Nonidet-P40 is an anhydrous liquid nonionic surface- active agent produced by the reaction of octyl phenol with 8.5-9.5 moles of ethylene oxide. Nonidet-P40 (NP-40) is a nonionic surfactant used in the isolation of membrane complexes. This product has been reformulated to be eco-friendly. The only observable differences are that the viscosity and handling characteristics are somewhat modified. Due to its nonionic structure, this product is compatible with anionic surfactants and is stable in the presence of acids, bases, and salts. It should not be mixed with concentrated oxidizing or reducing agents since the mixture of these compounds wit...s are stable non-corrosive products in their anhydrous state. They can be stored in plain steel tanks with piping, valves, and pumps of the same metal. Aqueous solutions of Nonidet-P40 must be stored in stainless steel or plastic lined tanks. The octyl phenol-ethylene oxide adducts are slightly hygroscopic. Where necessary, guard against atmospheric moisture pick-up, an inert gas blanket may be used. Group: Biochemicals. Alternative Names: HM2076; Igepal CA-630; T-DET O-series; ethoxylated octylphenol; T-DET O-9; Nonidet P40 substitute. Grades: Reagent Grade. CAS No. 9036-19-5. Pack Sizes: 100ml, 500ml, 1L, 2.5L. US Biological Life Sciences. | Worldwide |
| Poly(vinylidene fluoride-co-hexafluoropropylene) | The polymer product is a hydrophobic material that is insoluble in water or other polar solvents. Uses: Wire and cable coatings, flexible and corrosion-resistant tubing, and liners for pipes and tanks. Group: Bioelectronic materials hydrophobic polymers. Alternative Names: PVDF-HFP. CAS No. 9011-17-0. Pack Sizes: 100 g in poly bottle. Mole weight: (-CH2CF2-)x[-CF2CF(CF3)-]y. FC(F)=C.FC(F)=C(F)C(F)(F)F. | |
| TNKS656 | NVP-TNKS656, also known as TNKS656, is a potent and orally active Tankyrase Inhibitor. With an enthalpy-driven thermodynamic signature of binding, highly favorable physicochemical properties, and high lipophilic efficiency, NVP-TNKS656 is well suited for further in vivo validation studies. Bioactivity of TNKS656: TNKS2 IC50=6nM, LiPE=7.0, HEK298 STF IC50=3.5nM, Cmax/ Cellular IC50=23,000. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NVP-TNKS656; NVP-TNKS-656;NVP-TNKS 656;TNKS656; TNKS-656; TNKS 656. Product Category: Inhibitors. Appearance: solid powder. CAS No. 1419949-20-4. Molecular formula: C27H34N4O5. Mole weight: 494.58. Purity: >98%. IUPACName: N-(cyclopropylmethyl)-2-(4-(4-methoxybenzoyl)piperidin-1-yl)-N-((4-oxo-4,5,7,8-tetrahydro-3H-pyrano[4,3-d]pyrimidin-2-yl)methyl)acetamide. Canonical SMILES: O=C1NC(CN(CC2CC2)C(CN3CCC(C(C4=CC=C(OC)C=C4)=O)CC3)=O)=NC5=C1COCC5. Product ID: ACM1419949204. Alfa Chemistry ISO 9001:2015 Certified. |  |
| WIKI4 (2-[3-[[4-(4-Methoxyphenyl)-5-(4-pyr idinyl)-4H-1,2,4-triazol-3-yl]thio]propyl]-1H-benz [de]isoquinoline-1,3(2H)-dione) | Potent tankyrase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 838818-26-1. Pack Sizes: 5mg, 25mg. Molecular Formula: C29H23N5O3S. US Biological Life Sciences. | Worldwide |
| XAV 939 | A tankyrase (TNKS) inhibitor that antagonizes Wnt signaling via stimulation of β-catenin degradation and stabilization of axin. XAV 939 inhibits proliferation of the μ-catenin-dependent colon carcinoma cell line DLD-1. Group: Biochemicals. Alternative Names: 1, 5, 7, 8-Tetrahydro-2-[4- (trifluoromethyl) phenyl]-4H-thiopyrano[4, 3-d]pyrimidin-4-one; NVP-XAV 939. Grades: Highly Purified. CAS No. 284028-89-3. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| XAV939 (3, 5, 7, 8-Tetrahydro-2-[4- (trifluoromethyl) phenyl]-4H-thiopyrano[4, 3-d]pyrimidin-4-one) | A Tankyrase (TNKS) inhibitor (IC50 = 110nM for TNKS1 and 4nM for TNKS2). Antagonizes wnt signaling via stimulation of beta-catenin degradation and stabilization of axin. Inhibits proliferation of the mu-catenin-dependent colon carcinoma cell line DLD-1. Group: Biochemicals. Alternative Names: 3, 5, 7, 8-Tetrahydro-2-[4- (trifluoromethyl) phenyl]-4H-thi opyrano[4,3-d]pyrimidin-4-one. Grades: Highly Purified. CAS No. 284028-89-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| IKK epsilon/TBK1 Inhibitor II, MRT67307 (TANK Binding Kinase 1/IKKinducible Inhibitor II, N- (3- (5-Cyclopropyl -2- (3- (morpholino methyl ) phenylamino) pyrimidin-4-ylamino) propyl ) cyclobutane carboxamide) | A cell-permeable BX795 analog that acts as a potent, ATP-competitive, and reversible dual kinase inhibitor of TBK1/IKK epsilon (IC50 = 19 and 160nM, respectively) with excellent selectivity over IKKalpha and IKKbeta (IC50 > 10uM). Interacts with the TBK1 kinase dimer interface and stabilizes the inactive DFG-out conformation. Also blocks the activity of MARK (microtubule- associated protein (MAP)-microtubule affinity regulating kinase) 1, 2, 3, and 4 (IC50 = 27, 52, 36, and 41nM, respectively), SIK2 (IC50 = 67nM) and Aurora B, JAK2, and MLK1,3 (> than 90% inhibition at 1uM) in a 108-kinase panel. Increases TNF-alpha-stimulated NF-kB-dependent gene transcription in wild-type macrophages and enhances CREB-dependent gene transcription by promoting dephosphorylation of CREB-regulated transcription coactivator (CRTC3). Shown to aid TLR-stimulated production of anti-Inflammatory cytokines in macrophages while suppressing the secretion of pro-inflammatory cytokines. In response to pro-inflamm Group: Biochemicals. Grades: Highly Purified. CAS No. 495-85-2. Pack Sizes: 5mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. | Worldwide |
| Tankyrase1/2 Inhibitor III (TNKS1/2 Inhibitor III, Wnt Pathway Inhibitor XIV, 3-(4-Methoxyphenyl)-5-((4-(4-methoxyphenyl)-5-methyl-4H-1,2,4-triazol-3-ylthio)methyl)-1,2,4-oxadiazole) | A cell-permeable triazolylthiomethyl-oxadiazole compound that binds TNKS1/PARP5a and TNKS2/PARP5b with high affinity (=79 and 28nM, respectively), and acts as a potent and reversible TNKS1/2 dual inhibitor (IC50=33nM TNKS2 in an auto-PARsylation assay). Shown to interact with the adenosine diphosphate linker portion of the NAD+ donor site, and display excellent selectivity over PARP1 and PARP2 activities (IC50>19uM); stabilize Axin2 levels (EC50=709nM in SW480 cells), and antagonize Wnt signaling (IC50=215nM in HEK293-SuperTopFlash assay). Exhibits minimal activity towards cytochrome P450 enzymes (IC50=21 and 5.7uM for CYP2C9 and CYP3A4) and hERG ion channel (IC50>30uM), and adequate microsomal stability. Group: Biochemicals. Grades: Highly Purified. CAS No. 865565-29-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
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