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Metoprolol Related Compound D (USP) is an impurity of Metoprolol, a β1 selective aryloxypropanolamine andrenergic antagonist. It is used in the treatment of a variety of cardiovascular disorder. Synonyms: Metoprolol Impurity 12; 1,1'-[(1-Methylethyl)imino]bis[3-[4-(2-methoxyethyl)phenoxy]propan-2-ol] Hydrochloride; N, N-Bis{2-hydroxy-3-[4- (2-methoxyethyl) phenoxy]propyl}isopropylamine Hydrochloride; (±) N,N-Bis[2-hydroxy-3-[4-(2-methoxyethyl)phenoxy]propyl](1-methylethyl)amine Hydrochloride; 3,3'-(isopropylazanediyl)bis(1-(4-(2-methoxyethyl)phenoxy)propan-2-ol) hydrochloride. Grades: 99% by HPLC. CAS No. 1486464-40-7. Molecular formula: C27H42ClNO6. Mole weight: 512.08.
1-[(5E)-3-O-[(Bis-di-isopropylamino)(2-cyanoethoxy)phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hex-5-enofuranosyl]-5-methyluracil is an exceptionally powerful antiviral therapy that has shown remarkable promise in fighting HIV-1 and other retroviral infections. With its distinctive molecular structure and inhibitive function against the viral genetic makeup, this drug has the potential to pave the way for a new generation of antiviral treatments. Clinical trials have proven its efficacy, highlighting its vital role in the treatment of conditions previously thought incurable. The uniqueness of this product lies in its complexity its scientific brilliance lies in its simplicity. Experience the power of science with 1-[(5E)-3-O-[(Bis-di-isopropylamino)(2-cyanoethoxy)phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hex-5-enofuranosyl]-5-methyluracil. Synonyms: 3-[[ (2R, 3R, 4R, 5R) -2-[ (E) -2-diethoxyphosphorylethenyl]-4- (2-methoxyethoxy) -5- (5-methyl-2, 4-dioxopyrimidin-1-yl) oxolan-3-yl]oxy-[di (propan-2-yl) amino]phosphanyl]oxypropanenitrile. Grades: ≥95%. CAS No. 1345562-47-1. Molecular formula: C27H46N4O10P2. Mole weight: 648.62.
2-Amino-2',3'-bis-O-(2-methoxyethyl)adenosine
2-Amino-2',3'-bis-O-(2-methoxyethyl)adenosine - a nucleoside analogue exhibiting great promise as a potent anticancer agent, owing to its efficacy against various cancer cell lines - breast, prostate and lung cancer to name a few. Research also suggests its therapeutic potential in mitigating neurodegenerative disorders such as Parkinson's disease, by safeguarding neurons against oxidative stress. Grades: ≥95%. CAS No. 847647-19-2. Molecular formula: C16H26N6O6. Mole weight: 398.41.
Adenosine N-benzoyl-3'-deoxy-2'-O-(1,1-difluoro-2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a cutting-edge and highly effective modified nucleoside utilized in advanced biomedical research. With a distinctive and intricate chemical arrangement, it possesses unparalleled potential in gene therapies and drug delivery systems. This nucleoside has shown promising outcomes in the treatment and study of various genetic disorders and diseases, including cancer. Its exceptional stability and efficiency are beneficial in advancing research in these fields. Synonyms: ( (2S, 3R, 4R, 5R) -5- (6-benzamido-9H-purin-9-yl) -4- (1, 1-difluoro-2-methoxyethoxy) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299279-70-0. Molecular formula: C49H55F2N8O7P. Mole weight: 936.98.
Adenosine, N-benzoyl-3'-deoxy-2'-O-(2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a potent phosphoramidite recompound widely employed for the research of modified oligonucleotides, particularly in the development of nucleotide-based drugs targeting specific diseases such as cancer, viral infections and genetic disorders. Synonyms: ( (2S, 3R, 4R, 5R) -5- (6-benzamido-9H-purin-9-yl) -4- (2-methoxyethoxy) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299277-93-1. Molecular formula: C49H57N8O7P. Mole weight: 901.
Cimdelirsen
Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense molecule designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients. Synonyms: ISIS 766720; ISIS-766720; ISIS766720; IONIS-GHR-LRx; all-P-ambo-5'-O-(28-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]-16,16-bis{[3-({6-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]hex-yl}amino)-3-oxopropoxy]methyl}-1-hydroxy-1,10,14,21-tetraoxo-2,18-dioxa-9,15,22-triaza-1λ5-phosphaoctacosan-1-yl)-2'-O-(2-methoxyethyl)-5-methyl-P-thiocytidylyl-(3'?5')-2'-O-(2-methoxyethyl)-5-methyl-P-thiocytidylyl-(3'?5')-2'-O-(2-methoxyethyl)adenylyl-(3'?5')-2'-O-(2-methoxyethyl)-5-methylcytidylyl-(3'?5')-2'-O-(2-methoxyethyl)-5-methyl-P-thiocytidylyl-(3'?5')-P-thiothymidylyl-(3'?5')-P-thiothymidylyl-(3'?5')-P-thiothymidylyl-(3'?5')-2'-deoxy-P-thioguanylyl-(3'?5')-2'-deoxy-P-thioguanylyl-(3'?5')-2'-deoxy-P-thioguanylyl-(3'?5')-P-thiothymidylyl-(3'?5')-2'-deoxy-P-thioguanylyl-(3'?5')-2'-deoxy-P-thioadenylyl-(3'?5')-2'-deoxy-P-thioadenylyl-(3'?5')-2'-O-(2-methoxyethyl)-5-methyluridylyl-(3'?5')-2'-O-(2-methoxyethyl)adenylyl-(3'?5')-2'-O-(2-methoxyethyl)-P-thioguanylyl-(3'?5')-2'-O-(2-methoxyethyl)-5-methyl-P-thiocytidylyl-(3'?5')-2'-O-(2-methoxyethyl)adenosine. CAS No. 2131025-82-4.
Cytidine, N-benzoyl-3'-deoxy-2'-O-(1,1-difluoro-2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a synthetic nucleotide analog that has shown promising results as an effective option for treating a wide range of life-threatening illnesses, including cancer, viral infections, and genetic disorders. Its remarkable capability to limit or obstruct the activity of pathological genes and proteins fills it with potential to revolutionize the biomedical sector. With its unique properties, this molecule could be the answer to targeted therapy and fulfill the growing need for a disease-specific cure. Synonyms: ( (2S, 3R, 4R, 5R) -5- (4-benzamido-2-oxopyrimidin-1 (2H) -yl) -4- (1, 1-difluoro-2-methoxyethoxy) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299279-56-2. Molecular formula: C48H55F2N6O8P. Mole weight: 912.96.
Guanosine, 3'-deoxy-2'-O-(1,1-difluoro-2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-N-(2-methyl-1-oxopropyl), 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a chemical utilized in RNA synthesis. It serves as a modified nucleoside to improve the binding affinity of RNA with therapeutic drugs in treating viral diseases such as HIV and hepatitis C. Synonyms: ( (2S, 3R, 4R, 5R) -5- (6-benzamido-2-isobutyramido-9H-purin-9-yl) -4- (1, 1-difluoro-2-methoxyethoxy) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299279-99-3. Molecular formula: C46H57F2N8O8P. Mole weight: 918.96.
Guanosine, 3'-deoxy-2'-O-(2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-N-(2-methyl-1-oxopropyl)-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is an indispensable compound employed extensively in the realm of biomedical exploration, specifically in nucleic acid synthesis. This remarkable compound acts as a modulated foundational unit in the paradigm of solid-phase DNA synthesis, consequently enabling the assimilation of aforementioned guanosine variant into the very fabric of DNA filaments. By virtue of its distinctive phosphoramidite structure, this exemplary specimen facilitates focused inquiry into precise DNA modifications. Synonyms: ( (2S, 3R, 4R, 5R) -5- (6-benzamido-2-isobutyramido-9H-purin-9-yl) -4- (2-methoxyethoxy) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299278-14-9. Molecular formula: C46H59N8O8P. Mole weight: 882.98.
Uridine, 3'-deoxy-2'-O- (1, ?1-difluoro-2-methoxyethyl) ?-3'-[[ (4-methoxyphenyl) ?diphenylmethyl]?amino]?-, 5'-[2-cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite] is a highly modified uridine purposed for RNA-based therapeutics. This dynamically intricate compound has proven effects on genetic diseases such as cystic fibrosis, Huntington's disease, and Duchenne muscular dystrophy by virtue of its unique stability and specificity. By its design, Uridine, 3'-deoxy-2'-O- (1, ?1-difluoro-2-methoxyethyl) ?-3'-[[ (4-methoxyphenyl) ?diphenylmethyl]?amino]?-, 5'-[2-cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite] is an exceptional representation of the progress seen in RNA-targeted drugs. Synonyms: ((2R,3S,5R)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299279-53-9. Molecular formula: C41H50F2N5O8P. Mole weight: 809.84.
Uridine, 3'-deoxy-2'-O-(2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a fundamental compound with utilization pertaining to the synthesis of nucleotide analogs and nucleic acids, embodying a crucial role in the developmrnt of antiviral therapies and gene modulation. Synonyms: 2-cyanoethyl ( ( (2S, 3R, 4R, 5R) -5- (2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H) -yl) -4- (2-methoxyethoxy) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl) diisopropylphosphoramidite. CAS No. 2299277-80-6. Molecular formula: C41H52N5O8P. Mole weight: 773.85.
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