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| Product | Description | |
|---|---|---|
| Bis(4-methoxyphenyl)phosphine | Bis(4-methoxyphenyl)phosphine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Di-(4-methoxyphenyl)-phosphine. Product Category: Organic Phosphine Compounds. CAS No. 84127-04-8. Molecular formula: C14H15O2P. Mole weight: 246.24. IUPACName: bis(4-methoxyphenyl)phosphane. Canonical SMILES: COC1=CC=C(C=C1)PC2=CC=C(C=C2)OC. Product ID: ACM84127048-1. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Bis(4-methoxyphenyl)phosphine oxide | Bis(4-methoxyphenyl)phosphine oxide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: bis(p-methoxyphenyl)phosphine oxide; Bis(4-methoxyphenyl)phosphonic acid; di(p-methoxyphenyl)phosphinous acid; Phosphine oxide,bis(4-methoxyphenyl); Bis(4-methoxyphenyl)phosphine oxide; di(p-methoxyphenyl)phosphine oxide; di(4-methoxyphenyl)phosphine oxide; di-p-anisylphosphine oxide. Product Category: Organic Phosphine Compounds. CAS No. 15754-51-5. Molecular formula: C14H15O3P. Mole weight: 262.24. Purity: 0.97. IUPACName: bis(4-methoxyphenyl)-oxophosphanium. Canonical SMILES: COC1=CC=C(C=C1)[P+](=O)C2=CC=C(C=C2)OC. Product ID: ACM15754515. Alfa Chemistry ISO 9001:2015 Certified. | |
| 1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-CE phosphoramidite | 1-(2'-Deoxy-5'-O-DMT-2'-fluoro-β-D-arabinofuranosyl)thymine 3'-CE phosphoramidite is used in the solid-phase synthesis of modified oligonucleotides. The modifications enhance the stability and binding affinity of the oligonucleotides. These modified nucleotides are valuable in various applications, including the development of antisense oligonucleotides, siRNA, and other therapeutic nucleic acids, as well as in research settings where enhanced stability and specific interactions are required. Synonyms: 5'-O-dimethoxytrityl-2'-deoxy-2'-fluoroarabinothymidine-3'-[(2-cyanoethyl)-(N,N-diisopropropyl)]-Phosphoramidite; 2'-F-ANA-T-3'-CE-Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluoro-5-methyl-beta-D-arabinouridine-3'-CED-phosphoramidite; 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; 2'-Deoxy-2'-fluoro-5-Me-ara-U-3'-CED-phosphoramidite. Grade: 97%. CAS No. 208193-48-0. Molecular formula: C40H48FN4O8P. Mole weight: 762.82. |  |
| 1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil 3'-CE-phosphoramidite | 1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil 3'-CE-phosphoramidite is a novel nucleotide monophosphate with antiviral and anticancer properties. Synonyms: 2'-Fluoro-2'-deoxy-ara-U-3'-phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluoro-b-D-arabinouridine-3'-CEN-phosphoramidite; 5'-O-DMT-2'-F-2'-arabinofuranosyl-deoxyuridine 3'-CE phosphoramidite; 2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-α-D-arabinofuranosyl]-; 2'-ara-2'-F-2'-dU Phosphoramidite; 2'-F-U-ANA-CE Phosphoramidite. Grade: ≥95%. CAS No. 1190089-70-3. Molecular formula: C39H46FN4O8P. Mole weight: 748.78. | |
| 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-3-deoxy-β-D-threo-pentofuranosyl]-2,4(1H,3H)-pyrimidinedione | 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-3-deoxy-β-D-threo-pentofuranosyl]-2,4(1H,3H)-pyrimidinedione is a vital compound extensively utilized in the field of biomedicine. This product acts as a key reagent in the synthesis of modified nucleotides for research purposes. It is commonly employed in DNA and RNA synthesis, particularly in the development of oligonucleotides for therapeutic interventions targeting various diseases, such as cancer and viral infections. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-3-deoxy-β-D-threo-pentofuranosyl]-; 5-O-(4,4'-Dimethoxytrityl)-2-O-(diisopropylamino-2-cyanoethoxyphosphanyl)-1,3-dideoxy-1-uracil-1-yl-beta-D-threo-pentofuranose; (2R,3S,5S)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 3'-ara-dU Phosphoramidite; 5'-O-DMTr-3'-deoxyuridine ara-2'-phosphoramidite. Grade: ≥95%. CAS No. 161503-98-6. Molecular formula: C39H47N4O8P. Mole weight: 730.79. | |
| 2,?4(1H,?3H)?-?Pyrimidinedione, 1-?[5-?O-?[[bis(1-?methylethyl)?amino]?(2-?cyanoethoxy)?phosphino]?-?2,?3-?dideoxy-?2-?fluoro-?3-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?β-?D-?arabinofuranosyl]?-?5-?methyl- | The biochemical 2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2,3-dideoxy-2-fluoro-3-[[(4-methoxyphenyl)diphenylmethyl]amino]-β-D-arabinofuranosyl]-5-methyl-, is well known in the biomedical realm due to its anticancer effects, serving as a therapeutic agent for acute myeloid leukemia, chronic lymphocytic leukemia, and non-Hodgkin's lymphoma by impeding DNA synthesis and obstructing the propagation and dissemination of malignant cancerous cells, thereby proving to be an indispensable asset. Synonyms: 2-cyanoethyl (((2S,3R,4R,5R)-4-fluoro-3-(((4-methoxyphenyl)diphenylmethyl)amino)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite. CAS No. 329773-25-3. Molecular formula: C39H47FN5O6P. Mole weight: 731.79. | |
| 2-Aminopurine riboside CEP | 2-Aminopurine riboside CEP, an indispensable chemical entity extensively utilized within the biomedical sector, serves as a nucleoside analog. Its application predominantly revolves around the investigation and advancement of antiviral therapeutics designed to combat RNA virus-induced infections. Synonyms: N-[9-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-9H-purin-2-yl]-2-methylpropanamide; Phosphoramidous acid, bis(1-methylethyl)-, mono(2-cyanoethyl) ester, ester with N-[9-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-9H-purin-2-yl]-2-methylpropanamide; 2-Aminopurine-TBDMS-CE Phosphoramidite; 5'-Dimethoxytrityl-N2-isobutyryl-2-aminopurine riboside, 2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2-Amino Purine Riboside CED phosphoramidite. CAS No. 151059-65-3. Molecular formula: C50H68N7O8PSi. Mole weight: 954.18. | |
| 2'-Deoxy-5'-DMT-5-[3-(trifluoroacetylamino)-1-propynyl]-uridine 3'-CE phosphoramidite | 2'-Deoxy-5'-DMT-5-[3-(trifluoroacetylamino)-1-propynyl]-uridine 3'-CE phosphoramidite is a highly intricate and cutting-edge phosphoramidite derivative, manifesting immense potential in the realm of biomedical applications. Synonyms: 5-TFA-ap-dU phosphoramidite; alpha-[2-(Trifluoroacetylamino)ethylidyne]-3'-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5'-O-(4,4'-dimethoxytrityl)thymidine; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-[3-[(2,2,2-trifluoroacetyl)amino]-1-propyn-1-yl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-5-{3-[(trifluoroacetyl)amino]-1-propyn-1-yl}uridine. Grade: ≥98% by HPLC. CAS No. 120016-98-0. Molecular formula: C44H49F3N5O9P. Mole weight: 879.86. | |
| 2'-Deoxy-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite | 2'-Deoxy-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite is a crucial component in the biomedicine industry. It is employed for the synthesis of modified oligonucleotides with potent therapeutic potential. By incorporating this phosphoramidite, the resulting oligonucleotides display enhanced drug efficacy against specific diseases, such as cancer, viral infections, or genetic disorders. This product serves as a valuable tool for researchers and pharmaceutical companies striving to develop innovative nucleotide-based therapies. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-5-iodo-2'-deoxyuridine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphorramidite; 5-Iodo-dU-3'-phosphoramidite; 5'-O-DMTr-5-iodo-2'-dU-3'-CED phosphoramidite; 5-I-dU-CE Phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-5-iodouridine; 5-Iodo-dU CEP. Grade: 97%. CAS No. 178925-48-9. Molecular formula: C39H46IN4O8P. Mole weight: 856.69. | |
| 2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine 3'-CE-phosphoramidite | 2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine 3'-CE-phosphoramidite, an indispensable biochemical reagent, finds extensive application in the synthesis of modified nucleosides for groundbreaking biomedical research. Its usage is pivotal in the quest for novel drugs and therapies that target specific ailments, including cancer and viral infections. Additionally, this product's significance permeates the realm of nucleic acid chemistry, enabling researchers to delve into the intricacies of DNA and RNA modifications, thereby augmenting drug effectiveness and improving disease detection techniques. Synonyms: BP-40031; 5'-O-DMTr-N4-Fmoc-5-Me-dC-phosphoramidite; (9H-Fluoren-9-yl)methyl (1-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphino)oxy)tetrahydrofuran-2-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)carbamate; (9H-Fluoren-9-yl)methyl(1-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphino)oxy)tetrahydrofuran-2-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)carbamate; 9H-Fluoren-9-ylmethyl N-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]carbamate. CAS No. 176755-87-6. Molecular formula: C55H60N5O9P. Mole weight: 966.1. | |
| 2'-deoxypseudoU-CE Phosphoramidite | 2'-deoxypseudoU-CE Phosphoramidite is a paramount asset in the biomedical realm, enables the intricate research and development of modified oligonucleotides. The seamless integration of this compound into nucleic acids bestows upon researchers a platform to scrutinize the impact of altered nucleotides on pharmaceutical attributes and pathological pathways. Synonyms: 2'-Deoxy-5'-O-DMT-pseudouridine 3'-CE phosphoramidite; 2'-Deoxypseudouridine CEP; 5'-O-DMT-2'-deoxypseudouridine 3'-CE phosphoramidite; 5-[3-O-[Diisopropylamino(2-cyanoethoxy)phosphino]-5-O-(4,4'-dimethoxytrityl)-2-deoxy-beta-D-erythro-pentofuranosyl]pyrimidine-2,4(1H,3H)-dione; (1R)-1,4-Anhydro-5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-deoxy-1-(2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-D-erythro-pentitol. Grade: 95%. CAS No. 289712-98-7. Molecular formula: C39H47N4O8P. Mole weight: 730.8. | |
| 2'-Fluoro-2'-deoxy-ara-C(Bz)-3'-phosphoramidite | 2'-Fluoro-2'-deoxy-ara-C(Bz)-3'-phosphoramidite is a modified phosphoramidite used in the synthesis of oligonucleotides. This compound features a 2'-fluoro and 2'-deoxy modification on the arabinose sugar, a benzoyl (Bz) protective group on the nucleobase cytosine, and a phosphoramidite group at the 3' position. These modifications enhance the chemical stability and binding affinity of the resulting oligonucleotides, making them useful for applications in molecular biology, diagnostics, and therapeutic development. Synonyms: N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-2'-fluoro-b-D-arabinocytidine-3'-CED-phosphoramidite; N4-Benzoyl-2'-fluoro-5'-O-DMT-2'-arabinofuranosyl-deoxycytidine phosphoramidite; 4-(Benzoylimino)-1-{5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl}-1,4-dihydro-2-pyrimidinol; N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)cytidine 3'-CE-phosphoramidite; 5'-O-DMTr-2'-ara-F-C(Bz)-3'-CE-Phosphoramidite; 2'-F-2'-ara-Bz-dC Phosphoramidite; 2'-F-dC(Bz)-ANA-CE Phosphoramidite; 2'-F-2'-ara-N4-Bz-dC phosphoramidite. Grade: ≥95%. CAS No. 1404463-12-2. Molecular formula: C46H51FN5O8P. Mole weight: 851.90. | |
| 2-Isobutyrylamino-9-(2'-O-tert-butyldimethylsilyl-5'-O-DMT-b-D-ribofuranosyl)purine 3'-CE phosphoramidite | 2-Isobutyrylamino-9-(2'-O-tert-butyldimethylsilyl-5'-O-DMT-b-D-ribofuranosyl)purine 3'-CE phosphoramidite is an essential component in oligonucleotide synthesis for the biomedical industry. It is used in the modification and synthesis of nucleotide sequences targeting specific genes or diseases. Its unique properties allow for efficient and accurate incorporation into DNA and RNA strands, enabling researchers to study and develop therapeutic interventions for various conditions. Synonyms: 2'-OTBS 2-amino(iBu)purine amidite; N-[9-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-9H-purin-2-yl]butanamide. Grade: >95%. CAS No. 179558-91-9. Molecular formula: C50H68N7O8PSi. Mole weight: 954.20. | |
| 2'-O-Acetyl-N4-benzoyl-5'-O-(4,4'-dimethoxytrityl)arabinocytidine 3'-O-phosphoramidite | 2'-O-Acetyl-N4-benzoyl-5'-O-(4,4'-dimethoxytrityl)arabinocytidine 3'-O-phosphoramidite, a fundamental compound in oligonucleotide synthesis, plays a vital role in the advancement of diagnostic tools and therapeutic drugs within the biomedical field. Synonyms: DMTr-2'-ara-OAc-C(Bz)-3'-CE-Phosphoramidite; N-[1-[2-O-Acetyl-5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-β-D-arabinofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]benzamide; (2R,3S,4R,5R)-2-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)tetrahydrofuran-3-yl acetate; N4-benzoyl-(5'-O-(4,4'-dimethoxytrityl)-2'-O-acetyl-arabinocytidine-3'-[(2-cyanoethyl)-(N,N-diisopropropyl)]-Phosphoramidite; 5'-O-DMTr-2'-ara-OAc-C(Bz)-3'-CE-Phosphoramidite; Cytosine Arabinoside. Grade: ≥95%. CAS No. 675573-97-4. Molecular formula: C48H54N5O10P. Mole weight: 891.94. | |
| 2'-OMe C(Ac) PACE amidite | 2'-OMe C(Ac) PACE amidite is a reagent used in oligonucleotide synthesis. It contains a methyl (Me) group at the 2' position of ribose, cytosine (C) potentially protected with an acetyl (Ac) group, and incorporates a modification referred to as 'PACE'. This modification might introduce specific functionalities or properties to the oligonucleotide. The exact nature of 'PACE' would determine its role in the synthesis process and the properties of the resulting oligonucleotide. Synonyms: 2'-OMe C(Ac) PACE amidite; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[P-[2-(2-cyano-1,1-dimethylethoxy)-2-oxoethyl]-N,N-bis(1-methylethyl)phosphonamidite]; 1-Cyano-2-methylpropan-2-yl 2-((((2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(diisopropylamino)phosphaneyl)acetate; 5'-O-DMTr-2'-O-Me-C(Ac) PACE; 3'-O-(Diisopropylamino)phosphinoacetic acid α,α-dimethyl-β-cyanoethyl methyl ester N4-acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylcytidine. Grade: >98%. CAS No. 1355047-25-4. Molecular formula: C46H58N5O10P. Mole weight: 871.97. | |
| 2'-OMe G(iBu) PACE amidite | 2'-OMe G(iBu) PACE amidite is a reagent used in oligonucleotide synthesis. It contains a methyl (Me) group at the 2' position of ribose, guanosine (G) potentially protected with an isobutyl (iBu) group, and incorporates a modification referred to as 'PACE'. This modification introduces specific functionalities or properties to the oligonucleotide. The exact nature of 'PACE' would determine its role in the synthesis process and the characteristics of the resulting oligonucleotide. Synonyms: 2'-OMe G(iBu) PACE amidite; 5'-Dimethoxytrityl-N-isobutyryl-2'-OMe-Guanosine, 3'-O-(N,N-diisopropylamino)-phosphinyl-1,1-dimethyl-2-cyanoethyl acetate; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(2-methyl-1-oxopropyl)-, 3'-[P-[2-(2-cyano-1,1-dimethylethoxy)-2-oxoethyl]-N,N-bis(1-methylethyl)phosphonamidite]; 1-Cyano-2-methylpropan-2-yl 2-((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(diisopropylamino)phosphaneyl)acetate. Grade: >98%. CAS No. 1355047-26-5. Molecular formula: C49H62N7O10P. Mole weight: 940.05. | |
| 2'-O-Methyl-pyrrolo C CEP | 2'-O-Methyl-pyrrolo C CEP is a fluorescent analog of cytidine and a highly fluorescent proven to be useful for monitoring RNA secondary structure formation, where its fluorescence is reversibly quenched upon base-pairing. Synonyms: 3-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-methyl-β-D-ribofuranosyl]-1,3-dihydro-6-methyl-2H-pyrrolo[2,3-d]pyrimidin-2-one. CAS No. 644962-95-8. Molecular formula: C43H52N5O8P. Mole weight: 797.88. | |
| 2'-OMe U PACE amidite | 2'-OMe U PACE amidite is a reagent employed in oligonucleotide synthesis. It features a methyl (Me) group at the 2' position of ribose and contains uracil (U). 'PACE' likely refers to a specific modification or functional group incorporated into the nucleotide. This reagent facilitates the controlled synthesis of modified oligonucleotides with specific properties or functionalities, although the exact nature of 'PACE' would determine its specific role in the synthesis process. Synonyms: 2'-OMe U PACE amidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[P-[2-(2-cyano-1,1-dimethylethoxy)-2-oxoethyl]-N,N-bis(1-methylethyl)phosphonamidite]; 1-Cyano-2-methylpropan-2-yl 2-((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(diisopropylamino)phosphaneyl)acetate; 5'-O-DMTr-2'-O-Me-U PACE; 3'-O-(Diisopropylamino)phosphinoacetic acid α,α-dimethyl-β-cyanoethyl methyl ester 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyluridine; 5'-Dimethoxytrityl-2'-OMe-Uridine, 3'-O-(N,N-diisopropylamino)-phosphinyl-1,1-dimethyl-2-cyanoethyl acetate. Grade: >98%. CAS No. 411234-28-1. Molecular formula: C44H55N4O10P. Mole weight: 830.92. | |
| 2'-O-Propargyl G(iBu)-3'-phosphoramidite | 2'-O-Propargyl G(iBu)-3'-phosphoramidite is a vital compound extensively used in the field of biomedicine. This compound acting as a versatile building block for the synthesis of modified nucleosides and oligonucleotides. It finding applications in the development of therapeutic compounds, particularly for the reserch of viral infections and genetic diseases. Synonyms: N2-iBu-5'-O-DMTr-2'-O-propargylguanosine-3'-CED-phosphoramidite; N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl guanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; 5'-O-DMT-N2-isobutyryl-2'-O-propynylguanosine 3'-CE phosphoramidite; 5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-N-(2-methyl-1-oxopropyl)?-2'-O-2-propynyl-guanosine 3'-[2-cyanoethyl bis(1-methylethyl)?phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-2-propyn-1-ylguanosine; DMTr-2'-O-propargyl-rG(iBu)-3'-CE-Phosphoramidite; 5'-O-DMT-2'-O-Propargyl-N2-isobutyryl-Guanosine 3'-CE phosphoramidite; N2-iBu-DMT-2'-O-propargyl-G-CE-Phosphoramidite; 2'-O-propargyl Guanosine (n-ibu) CED phosphoramidite. Grade: ≥95%. CAS No. 171486-61-6. Molecular formula: C47H56N7O9P. Mole weight: 893.96. | |
| 2'-O-tert-Butyldimethylsilyl-5-O-DMT-nebularine 3'-CE phosphoramidite | 2'-O-tert-Butyldimethylsilyl-5-O-DMT-nebularine 3'-CE phosphoramidite is a cutting-edge substance harboring extraordinary potential, catalyzing the research and development of tailored oligonucleotides, augmenting the efficiency and precision of nucleic acid sequence alterations. Synonyms: 9-(2'-O-tert-Butyldimethylsilyl-5'-O-DMT-b-D-ribofuranosyl)purine 3'-CE phosphoramidite; 2'-OTBS Purine amidite; 9-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-9H-purine; Nebularine 3''-CE phosphoramidite; Purine Riboside CED phosphoramidite. Grade: >95%. CAS No. 151132-95-5. Molecular formula: C46H61N6O7PSi. Mole weight: 869.07. | |
| 3-Deaza-3-methyl-dA CEP | 3-Deaza-3-methyl-dA CEP, a pivotal compound within the biomedicine realm, boasts indispensability. Its principal application resides in the amalgamation of DNA analogs and the adjustment of nucleosides, serving as a catalyst for cutting-edge investigations. By assuming a critical role in anti-viral drug development and genetic disease analysis, this product furnishes invaluable perspectives on diverse therapeutic interventions. Synonyms: Benzamide, N-benzoyl-N-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-beta-D-erythro-pentofuranosyl]-7-methyl-1H-imidazo[4,5-c]pyridin-4-yl]-; DTXSID001098448; N-Benzoyl-N-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-beta-D-erythro-pentofuranosyl]-7-methyl-1H-imidazo[4,5-c]pyridin-4-yl]benzamide. CAS No. 1031750-37-4. Molecular formula: C56H59N6O8P. Mole weight: 975.08. | |
| 3'-F-3'-dA(Bz)-2'-phosphoramidite | 3'-F-3'-dA(Bz)-2'-phosphoramidite, an indispensable compound widely employed in the biomedical sector for the synthesis of oligonucleotides and nucleic acid analogs, holds paramount importance. Its modified structure renders it adept at enhancing stability, selectivity, and binding properties. Synonyms: N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-deoxy-3'-fluoroadenosine-2'-CED-phosphoramidite; N-[9-[(2R,3S,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-4-fluorooxolan-2-yl]purin-6-yl]benzamide; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-3'-deoxy-3'-fluoroadenosine; 5'-DMT-3'-fluoro-DA(BZ) amidite; 3'-F A(Bz) 2'-amidite. Grade: ≥95%. CAS No. 2127174-09-6. Molecular formula: C47H51FN7O7P. Mole weight: 875.92. | |
| 3'-O-(4,4'-Dimethoxytrityl)-thymidine-5'-cyanoethyl-Phosphoramidite | 3'-O-(4,4'-Dimethoxytrityl)-thymidine-5'-cyanoethyl-Phosphoramidite is a phosphoramidite used in the synthesis of oligonucleotides. It is specifically designed for use in automated oligonucleotide synthesis systems, ensuring precise and controlled addition of thymidine units in the synthesis of custom DNA sequences. Synonyms: 5'-O-[(Diisopropylamino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)thymidine; DMT-dT-CE Inverted Phosphoramidite; 3'-O-(4,4'-Dimethoxytrityl)-thymidine-5'-cyanoethyl Phosphoramidite; Thymidine, 3'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; Thymidine, 3'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]. Grade: ≥98%. CAS No. 134031-86-0. Molecular formula: C40H49N4O8P. Mole weight: 744.81. | |
| 3'-O-DMT-N6-Benzoyl-Cytidine TNA 2'-CE phosphoramidite | TNA 2'-CE oligonucleotide synthesis necessitates 3'-O-DMT-N6-benzoyl-cytidine, and our TNA 2'-CE phosphoramidite is precisely engineered for just that purpose. Researchers within the biomedicine discipline rely heavily on our product due to their capacity to incorporate TNA monomers as they fabricate artificial nucleic acids for gene-based therapeutics and pharmacological advancement. Synonyms: Phosphoramidous acid, bis(1-methylethyl)-, (2R,3R,4S)-2-[4-(benzoylamino)-2-oxo-1(2H)-pyrimidinyl]-4-[bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-furanyl 2-cyanoethyl ester; DMTr-TNA C(Bz)-amidite; (2R,3R,4S)-2-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; TNA-C(Bz)-CE-Phosphoramidite; N-Benzoyl-1-[(2R)-3alpha-[(diisopropylamino)(2-cyanoethoxy)phosphinooxy]-4beta-(4,4'-dimethoxytrityloxy)tetrahydrofuran-2beta-yl]cytosine; DMTr-TNA-C(Bz)-Phosphoramidite. Grade: 98%. CAS No. 325683-96-3. Molecular formula: C45H50N5O8P. Mole weight: 819.90. | |
| 5-Br-rU Phosphoramidite | 5-Br-rU Phosphoramidite, a vital constituent in biomedical research and drug development, finds utility as a building block for oligonucleotide union and holds immense potential in therapies for diseases like cancer and viral infections. Notably, owing to its distinctive chemical features, it can tinker with the structure and function of nucleic acids, facilitating precise treatment, and improved delivery of medications. Synonyms: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-bromo-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-5-bromo-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]uridine; 5-Bromo-2'-O-tert-butylbutyldimethylsilyl-5'-O-DMT-D-uridine 3'-CE phosphoramidite; Br-U-CE Phosphoramidite; 5-Bromo Uridine CED phosphoramidite; 5-Bromo 2'-TBDMS Uridine 3'-CE phosphoramidite; DMTr-2'-O-TBDMS-5-Br-rU-3'-CE-Phosphoramidite. Grade: ≥97% by HPLC. CAS No. 166733-98-8. Molecular formula: C45H60BrN4O9PSi. Mole weight: 939.96. | |
| 5'-DMT-2'-O-Me-PseudoUridine-CE-Phosphoramidite | 5'-DMT-2'-O-Me-PseudoUridine-CE-Phosphoramidite is a phosphoramidite derivative used in the synthesis of modified oligonucleotides for biomedical research. It enables the incorporation of 2'-O-methyl-pseudouridine modifications into RNA sequences, enhancing stability and specific RNA-protein interactions. Synonyms: 2'-O-Methyl-5'-O-DMT-pseudoUridine 3'-CE phosphoramidite; pseudoUridine (with 5'-DMT, 3'-phosphoramidite, and 2'-OMe); 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-methyl-β-D-ribofuranosyl]-; 5-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-methyl-β-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione. Grade: ≥95% by HPLC. CAS No. 199737-09-2. Molecular formula: C40H49N4O9P. Mole weight: 760.81. | |
| 5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite | It is a modified ribonucleoside analogue suitable for incorporation into small interfering RNA (siRNA) to enhance RNA stability in biological applications such as gene silencing. Synonyms: 5'-Dimethoxytrityl-1-methyl-pseudouridine, 2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5-[5-O-[bis(4-methoxyphenyl)?phenylmethyl]?-3-O-[[bis(1-methylethyl)?amino]?(2-cyanoethoxy)?phosphino]?-2-O-[(1,?1-dimethylethyl)?dimethylsilyl]?-β-D-ribofuranosyl]?-1-methyl-2,?4(1H,?3H)?-pyrimidinedione; 2'-O-TBDMS-N1-Me-Pseudouridine CEP; 5'-O-DMTr-2'-O-TBDMS-N1-methylpseudouridine 3'-(cyanoethyl-N,N-diisopropyl)phosphoramidite; 5'-O-DMT-2'-O-TBDMS-N1-Me-pU Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(t-butyldimethylsilyl)-N1-methyl-Pseudouridine-3'-cyanoethyl Phosphoramidite. Grade: ≥98%. CAS No. 875302-45-7. Molecular formula: C46H63N4O9PSi. Mole weight: 875.07. | |
| 5'-DMT-2'-O-TBDMS-PseudoUridine-CE-Phosphoramidite | 5'-DMT-2'-O-TBDMS-PseudoUridine-CE-Phosphoramidite is a valuable compound primarily employed for the research and development of RNA molecules required for diagnostic purposes or therapeutic interventions. This compound plays a crucial role in the development of drugs targeting specific diseases and disorders, such as cancers or viral infections. It facilitates efficient nucleotide incorporation and ensures accurate development of RNA sequences. Synonyms: 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-pseudoUridine 3'-CE phosphoramidite; PseudoUridine-CE Phosphoramidite; Pseudouridine CEP; 5-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-beta-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione; 5'-O-DMTr-2'-O-TBDMS-Pseudouridine-3'-CE Phosphoramidite; 5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-Pseudouridine-3'-cyanoethyl-Phosphoramidite. Grade: ≥95%. CAS No. 163496-23-9. Molecular formula: C45H61N4O9PSi. Mole weight: 861.05. | |
| 5'-DMT-3'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite | 5'-DMT-3'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite, a highly valued compound within the biomedicine sector, plays a pivotal role in the synthetic production of altered nucleic acids. Primarily employed as a fundamental unit during oligonucleotide formation, it showcases tremendous potential in advancing RNA-based therapeutic interventions. Through its exceptional capability, this product empowers precise and effective nucleoside modification, enabling targeted remedies for an array of prevalent ailments including viral afflictions and hereditary anomalies. Synonyms: 5'-DMT-3'-O-TBDMS-N1-Methyl-PseudoUridine 2'-Phosphoramidite; 5-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-3-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-1-methyl-2,4(1H,3H)-pyrimidinedione; (2S,3S,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-2-(1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. Grade: ≥95%. CAS No. 875302-47-9. Molecular formula: C46H63N4O9PSi. Mole weight: 875.07. | |
| 5'-DMT-3'-O-TBDMS-PseudoUridine-CE-Phosphoramidite | 5'-DMT-3'-O-TBDMS-PseudoUridine-CE-Phosphoramidite, an indispensable compound in the thriving biomedical sector, serves as a pivotal component for oligonucleotide synthesis. This ground-breaking technique unlocks unparalleled potential to combat a myriad of afflictions encompassing cancer, viral infections, and genetic aberrations. Synonyms: 5'-DMT-3'-O-TBDMS-PseudoUridine 2'-Phosphoramidite; 5-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-3-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione; (2S,3S,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-2-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. Grade: ≥95%. Molecular formula: C45H61N4O9PSi. Mole weight: 861.05. | |
| 5'-DMT-NHS-Carboxy dU 3'-Phosphoramidite | 5'-DMT-NHS-Carboxy dU 3'-Phosphoramidite is a phosphoramidite compound used in the synthesis of oligonucleotides. It is designed to incorporate a modified deoxyuridine nucleotide into DNA strands, which can enhance the stability and functionality of the synthesized oligonucleotides. This compound is used to improve the metabolic stability and binding affinity of the synthesized oligonucleotides, making them more suitable for specific biological applications such as gene regulation, and antisense therapy. Synonyms: N-Hydroxysuccinimide carboxy-dT phosphoramidite; 2-Propenoic acid, 3-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinyl]-, 2,5-dioxo-1-pyrrolidinyl ester; 2,5-Dioxo-1-pyrrolidinyl 3-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinyl]-2-propenoate; NHS-Carboxy-dT; 5'-Dimethoxytrityl-5-[3-acrylate NHS ester]-2'-deoxyUridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5'-DMT-5-NHS-carboxy-2'-deoxy-rU 3'-Phosphoramidite. CAS No. 1354695-41-2. Molecular formula: C46H52N5O12P. Mole weight: 897.91. | |
| 5-Ethylcarboxy-dC(Bz) Phosphoramidite | 5-Ethylcarboxy-dC(Bz) Phosphoramidite is a modified phosphoramidite where the cytosine base is functionalized with an ethylcarboxy group at the 5-position and protected with a benzoyl (Bz) group on the exocyclic amine. The sugar moiety is designed with a 3'-phosphoramidite functionality for compatibility with automated DNA synthesis. This compound is commonly used to introduce chemically modified cytosine residues into oligonucleotides, enabling studies on DNA-protein interactions, epigenetic modifications, and the effects of base alterations on nucleic acid stability and function. It is particularly useful in therapeutic oligonucleotide development and molecular biology research. Synonyms: 5-Pyrimidinecarboxylic acid, 4-(benzoylamino)-1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-1,2-dihydro-2-oxo-, ethyl ester; 5-Carboxy-dC-CE Phosphoramidite; 5'-Dimethoxytrityl-N-benzoyl-5-ethylcarboxy-2'-deoxycytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; DNA 5-carbethoxy-C(Bz) amidite. Grade: ≥95%. CAS No. 1535202-71-1. Molecular formula: C49H56N5O10P. Mole weight: 905.97. | |
| 5-Nitroindole 3'-CE phosphoramidite | 5-Nitroindole 3'-CE Phosphoramidite is a modified phosphoramidite used in the synthesis of oligonucleotides with specific functional modifications. The 5-nitroindole component refers to an indole ring structure that is functionalized with a nitro group at the 5-position, which introduces electron-withdrawing properties that can influence the oligonucleotide's interaction with other molecules, such as nucleic acids or proteins. The nitroindole modification may enhance the stability, reactivity, or specificity of the oligonucleotide for particular applications. This phosphoramidite is useful in synthesizing oligonucleotides for applications in research involving fluorescence-based detection, molecular interactions, or RNA interference. The nitroindole modification may also offer advantages in terms of increased stability or enhanced binding properties for therapeutic applications, such as gene silencing or antisense oligonucleotides. Synonyms: 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-5-nitro-1H-indole; 5-Nitroindole-CE phosphoramidite; 5'-Dimethoxytrityl-2'-deoxy-5-nitroindole-ribofuranosyl, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; DNA 5-NO2-indole amidite. Grade: ≥96%. CAS No. 911823-92-2. Molecular formula: C43H49N4O8P. Mole weight: 780.86. | |
| 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-3-formylindole-ribofuranosyl-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-3-formylindole-ribofuranosyl-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite, a compound widely employed in biomedicine, exhibits extraordinary versatility. It serves as an essential phosphoramidite building block during the synthesis of modified oligonucleotides, thereby holding immense potential in fields like antisense therapeutics, gene therapy, and molecular diagnostics. Synonyms: 5-Formylindole-CE Phosphoramidite; 1H-Indole-3-carboxaldehyde, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-. Grade: ≥95%. CAS No. 460355-05-9. Molecular formula: C44H50N3O7P. Mole weight: 763.86. | |
| 5'-O-DMT-2'-O-(2-methoxyethyl)uridine 3'-CE phosphoramidite | 5'-O-DMT-2'-O-(2-methoxyethyl)uridine 3'-CE phosphoramidite is a building block for introducing uridine units into oligonucleotides. Synonyms: 2'-O-MOE-U-3'-phosphoramidite; 5'-O-DMTr-2'-O-(2-methoxyethyl)-uridine-3'-CED-phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)uridine 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-(2-methoxyethyl)uridine. Grade: ≥95%. CAS No. 163759-97-5. Molecular formula: C42H53N4O10P. Mole weight: 804.86. | |
| 5'-O-DMT-2'-O-TBDMS-L-Uridine 3'-CE phosphoramidite | 5'-O-DMT-2'-O-TBDMS-L-Uridine 3'-CE phosphoramidite, a highly versatile and indispensable compound within the biomedical industry, occupies a paramount position in the synthesis of oligonucleotides of immense significance. Blending seamlessly with various applications including gene therapy, nucleic acid-based diagnostics, and drug development, this invaluable marvel propels the progress of medical science. Its inherent ability to modify nucleotide sequences bestows unmatched stability and facilitates target-specific drug conveyance, fostering advancements in the treatment of multifarious diseases, encompassing cancer and genetic disorders. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-; 1-[2-O-(tert-Butyldimethylsilyl)-3-O-[diisopropylamino(2-cyanoethoxy)phosphino]-5-O-(4,4'-dimethoxytrityl)-beta-L-ribofuranosyl]uracil; DMT-2'-O-TBDMS-L-rU Phosphoramidite; L-RNA 2'-OTBS U amidite; 5'-O-DMT-2'-O-TBDMS-L-U 3'-CE phosphoramidite. Grade: ≥98% by HPLC. CAS No. 144490-31-3. Molecular formula: C45H61N4O9PSi. Mole weight: 861.06. | |
| 5'-O-DMT-2'-O-TBDMS-N2-isobutyryl-L-Guanosine 3'-CE phosphoramidite | 5'-O-DMT-2'-O-TBDMS-N2-isobutyryl-L-Guanosine 3'-CE phosphoramidite, a sophisticated compound integral to the production of custom oligonucleotides, showcases remarkable versatility. It serves as a phosphoramidite foundation during solid-phase DNA synthesis, facilitating the integration of guanosine modifications. By harnessing this product, nucleic acid researchers can probe gene expression or delve into the impact of guanosine alterations on ailments such as cancer. Synonyms: DMT-2'-O-TBDMS-L-rG(ibu) Phosphoramidite; N-[9-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-2-methylpropanamide; L-rG(ibu) Phosphoramidite; 5'-O-DMTr-2'-O-TBDMS-L-G(iBu)-3'-CE-Phosphoramidite; N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-L-guanosine-3'-cyanoethyl Phosphoramidite. Grade: ≥98% by HPLC. CAS No. 679809-76-8. Molecular formula: C50H68N7O9PSi. Mole weight: 970.19. | |
| 5'-O-DMT-2'-O-TBDMS-N4-Acetyl-L-Cytidine 3'-CE phosphoramidite | 5'-O-DMT-2'-O-TBDMS-N4-Acetyl-L-Cytidine 3'-CE phosphoramidite, a remarkable substance within the biomedical field, holds immense significance. Its application in the synthesis of altered oligonucleotides for therapeutic intentions is widespread. Through the specific manipulation and addressing of genetic material, particularly RNA, it exhibits a pivotal role in combating diverse ailments. Boasting an exceptional composition, this product possesses the power to revolutionize precision medicine and propel the progression of targeted therapies. Synonyms: Acetamide, N-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-; DMT-2'-O-TBDMS-L-rC(Ac) Phosphoramidite. Grade: ≥98% by HPLC. CAS No. 237060-94-5. Molecular formula: C47H64N5O9PSi. Mole weight: 902.11. | |
| 5'-O-DMT-2'-O-TBDMS-N6-Benzoyl-L-Adenosine 3'-CE phosphoramidite | 5'-O-DMT-2'-O-TBDMS-N6-Benzoyl-L-Adenosine 3'-CE phosphoramidite is a crucial reagent used in the synthesis of oligonucleotides for biomedical research. It enables the efficient introduction of N6-benzoyl-L-Adenosine residues into the oligonucleotide chain, thus allowing the study of adenosine-modified nucleic acids. This product finds applications in drug discovery, gene therapy, and understanding diseases related to adenosine signaling pathways. Synonyms: Benzamide, N-[9-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-9H-purin-6-yl]-; N-Benzoyl-9-{5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-O-[dimethyl(2-methyl-2-propanyl)silyl]-β-L-ribofuranosyl}-9H-purin-6-amine; DMT-2'-O-TBDMS-L-rA(Bz) Phosphoramidite; 5'-O-DMTr-2'-O-TBDMS-L-A(Bz)-3'-CE-Phosphoramidite; N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-L-adenosine-3'-cyanoethyl Phosphoramidite. Grade: ≥98% by HPLC. CAS No. 1803193-36-3. Molecular formula: C53H66N7O8PSi. Mole weight: 988.21. | |
| 5'-O-DMT-2'-O-tert-Butyldimethylsilyl-Inosine 3'-CE phosphoramidite | Antiviral and anticancer drug for cells infected with influenza A virus, herpes simplex virus type 2, and human lymphocytic leukemia cells. Synonyms: 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-inosine 3'-CE phosphoramidite; 2'-O-(tert-Butyldimethylsilyl)-3'-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)inosine; Inosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]inosine; DMT-2'-O-TBDMS-I-CE-Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(t-butyldimethylsilyl)-inosine-3'-cyanoethyl Phosphoramidite. Grade: ≥97% by HPLC. CAS No. 261518-12-1. Molecular formula: C46H61N6O8PSi. Mole weight: 885.07. | |
| 5'-O-DMT-2'-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine 3'-CE phosphoramidite | 5'-O-DMT-2'-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine 3'-CE phosphoramidite is a classic protected 2-OTBDMS phosphoramidite used for incorporating ribo-G into synthetic oligonucleotides. Synonyms: 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite; iBu-rG CE phosphoramidite; DMT-2'-O-TBDMS-rG(iBu) Phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]-N-isobutyrylguanosine; 5'-O-DMT-2'-O-TBDMS-N2-Isobutyryl-Guanosine-CE Phosphoramidite; 2'-TBDMS-ibu-G-CE-Phosphoramidite; DMT-2'-O-TBDMS-G(iBu)-CE-Phosphoramidite; N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-guanosine-3'-cyanoethyl Phosphoramidite. Grade: ≥98% by HPLC. CAS No. 147201-04-5. Molecular formula: C50H68N7O9PSi. Mole weight: 970.18. | |
| 5'-O-DMT-2'-O-tert-Butyldimethylsilyl-N6-methyl-adenosine 3'-CE phosphoramidite | 5'-O-DMT-2'-O-tert-Butyldimethylsilyl-N6-methyl-adenosine 3'-CE phosphoramidite is a vital compound used in the biomedical industry for synthesizing RNA molecules. This phosphoramidite aids in the incorporation of modified adenosine bases during RNA synthesis, enabling researchers to study specific drug targets or diseases related to N6-methyladenosine methylation. By providing precise adenosine modifications, this product facilitates the investigation of gene expression and regulatory mechanisms, leading to potential breakthroughs in drug discovery and disease understanding. Synonyms: Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N6-Me-rA phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]-N-methyladenosine; N6-Me-DMT-2'-O-TBDMS-A-CE Phosphoramidite; N6-Methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-adenosine-3'-cyanoethyl-Phosphoramidite; 5'-O-DMT-2'-O-TBDMS-N6-methyl-Adenosine 3'-CE phosphoramidite; DMTr-2'-O-TBDMS-N6-Me-rA-3'-CE-Phosphoramidite. Grade: ≥98% by HPLC. CAS No. 588698-79-7. Molecular formula: C47H64N7O7PSi. Mole weight: 898.11. | |
| 5'-O-DMT-3'-O-TBDMS-N6-Benzoyl-Adenosine 2'-CE phosphoramidite | 5'-O-DMT-3'-O-TBDMS-N6-Benzoyl-Adenosine 2'-CE phosphoramidite is an antiviral nucleoside phosphoramidite for DNA synthesis. Synonyms: N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CE phosphoramidite; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 3'-TBDMS-Bz-rA Phosphoramidite; N-Benzoyl-2'-O-[2-cyanoethoxy(diisopropylamino)phosphino]-3'-O-(tert-butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)adenosine; N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-(t-butyldimethylsilyl)-adenosine-2'-cyanoethyl phosphoramidite; 5'-O-DMTr-3'-O-TBDMS-A(Bz)-2'-CE-Phosphoramidite; N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-(t-butyl-dimethylsilyl)-adenosine-2'-cyanoethyl Phosphoramidite. Grade: ≥95%. CAS No. 129451-75-8. Molecular formula: C53H66N7O8PSi. Mole weight: 988.19. | |
| 5'-O-DMT-N2-isobutyryl-2'-O-?methoxyethylguanosine 3'-CE phosphoramidite | 5'-O-DMT-N2-isobutyryl-2'-O-methoxyethylguanosine 3'-CE phosphoramidite is used to incorporate 2'-O-methoxyethyl-modified G into oligonucleotides, which is useful for antisense RNA. Synonyms: 5'-O-DMTr-N2-iBu-2'-O-MOE-guanosine-3'-CED phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N2-iso-butyroyl-2'-O-(2-methoxyethyl)guanosine-3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]phosphoramidite; 2'-MOE-G(iBu)-3'-phosphoramidite; DMT-2M-O-Me-rG(ib) amidite; N2-isobutyryl-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite; N-Isobutyryl-2'-O-(2-methoxyethyl)-3'-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5'-O-(4,4'-dimethoxytrityl)guanosine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-(2-methoxyethyl)guanosine. Grade: ≥95%. CAS No. 251647-55-9. Molecular formula: C47H60N7O10P. Mole weight: 913.99. | |
| 5'-O-DMT-N4-Acetyl-2'-fluoro-2'-arabinofuranosyl-deoxycytidine 3'-CE phosphoramidite | 5'-O-DMT-N4-Acetyl-2'-fluoro-2'-arabinofuranosyl-deoxycytidine 3'-CE phosphoramidite is a crucial reagent extensively used in the biomedical industry for the synthesis of nucleosides and nucleotides. This product plays a significant role in the development of therapeutic drugs targeting various diseases, including viral infections and cancer. With its unique properties, it enables researchers to design and fabricate novel nucleoside analogs with potential antiviral and anticancer activities, contributing to advancements in biomedicine. Synonyms: 2'-F-2'-ara-Ac-dC Phosphoramidite; 4-Acetamido-1-{5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl}-2(1H)-pyrimidinone; 2(1H)-Pyrimidinone, 4-(acetylamino)-1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl]-; N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-deoxy-2'-fluorocytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite. Grade: ≥97% by HPLC. Molecular formula: C41H49FN5O8P. Mole weight: 789.83. | |
| 5'-O-DMT-N4-Benzoyl-5-Methy-2'-O-(2-methoxyethyl)cytidine 3'-CE phosphoramidite | 5'-O-DMT-N4-Benzoyl-5-Methy-2'-O-(2-methoxyethyl)cytidine 3'-CE phosphoramidite is used to incorporate methyl-C modified with 2'-O-methoxyethyl into oligonucleotides, which is useful for anti-sense RNA. Synonyms: N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-CE phosphoramidite; 2'-O-MOE-N4-Bz-5-Me-C Phosphoramidite; 5-Me-DMT-2'-O-MOE-C(Bz)-CEP; N4-Benzoyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-cytidine-3'-cyanoethyl phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-(2-methoxyethyl)-5-methyl-3,4-dihydrocytidine; 5'-O-DMT-2'-O-MOE-MeC(Bz) 3'-CE phosphoramidite. Grade: ≥98% by HPLC. CAS No. 163759-94-2. Molecular formula: C50H60N5O10P. Mole weight: 922.01. | |
| 5'-O-DMT-N4-Benzoyl-5-methyl-2'-O-methylcytidine 3'-CE phosphoramidite | 5'-O-DMT-N4-Benzoyl-5-methyl-2'-O-methylcytidine 3'-CE phosphoramidite is a phosphoramidite analogue with antiviral, anticancer and antimalarial properties. Synonyms: N4-Benzoyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-cytidine-3'-cyanoethyl phosphoramidite; 2'-OMe-N6-Bz-5-Me-C Phosphoramidite; 5'-DMT-N4-Bz-2'-OMe-5-Me-C phosphoramidite; DMT-2'-OME-dC(Bz)-CE-Phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-5-methyl-2'-O-methylcytidine; 5-Me-DMT-2'-O-Me-C(Bz)-CE-Phosphoramidite; 5'-O-DMT-2'-O-Me-MeC(Bz)-3'-CE-Phosphoramidite. Grade: ≥98% by HPLC. CAS No. 166593-57-3. Molecular formula: C48H56N5O9P. Mole weight: 877.98. | |
| 5'-O-DMT-N4-Isobutyryl-2'-deoxycytidine-3'-CE Phosphoramidite | 5'-O-DMT-N4-Isobutyryl-2'-deoxycytidine-3'-CE Phosphoramidite, a chemical reagent widely employed in oligonucleotide synthesis for biomedical research, manifests remarkable versatility in targeting a wide range of ailments, spanning from cancer to genetic disorders. With its ready availability and proven efficacy in in-vitro experiments, this chemical reagent is the go-to choice for generating novel and effective therapeutic oligonucleotides. Synonyms: IBU-DC Phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-N-isobutyrylcytidine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-{(2-cyanoethoxy)[di(propan-2-yl)amino]phosphanyl}-2'-deoxy-N-(2-methylpropanoyl)cytidine; N-Isobutyryl-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine; IBU-dC CEP. Grade: ≥98% by HPLC. CAS No. 110522-84-4. Molecular formula: C43H54N5O8P. Mole weight: 799.90. | |
| 5'-O-DMT-N6-Acetyl-2'-deoxyadenosine 3'-CE phosphoramidite | 5'-O-DMT-N6-Acetyl-2'-deoxyadenosine 3'-CE phosphoramidite is a key component for the synthesis of modified oligonucleotides, which have applications in gene therapy and antiviral drug development. This phosphoramidite can be used to introduce an N6-acetyldeoxyadenosine modification to oligonucleotide strands, which has been shown to enhance their cellular uptake and improve their stability towards nucleases. It is also useful for generating oligonucleotides with 3'-CE modifications, which can improve their binding and selectivity towards complementary RNA targets. Synonyms: Adenosine N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxyadenosine. Grade: ≥98% by HPLC. CAS No. 1027734-01-5. Molecular formula: C42H50N7O7P. Mole weight: 795.86. | |
| 5'-O-DMT-N6-Phenoxyacetyl-2'-deoxyadenosine 3'-CE phosphoramidite | 5'-O-DMT-N6-Phenoxyacetyl-2'-deoxyadenosine 3'-CE phosphoramidite is a crucial recompound in the dynamic biomedical field, exhibiting unparalleled versatility in application in synthesizing sophisticated modified oligonucleotides. Synonyms: 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine 3'-CE phosphoramidite; DMT-dA(tac) Phosphoramidite; N-(Phenoxyacetyl)-3'-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(phenoxyacetyl)-adenosine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]. Grade: 95%. CAS No. 110543-74-3. Molecular formula: C48H54N7O8P. Mole weight: 887.98. | |
| 5'-O-DMTr-L-thymidine-3'-CED phosphoramidite | 5'-O-DMTr-L-thymidine-3'-CED phosphoramidite is a modified phosphoramidite used in solid-phase oligonucleotide synthesis. This compound is used for the preparation of custom oligonucleotides, such as for DNA sequencing, gene synthesis, or other nucleic acid-based applications. The L-configuration of the sugar in the name may imply a chiral modification, which could influence the nucleic acid's properties in certain contexts. Synonyms: 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-L-erythro-pentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; (2S,3R,5S)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; L-DNA T amidite; beta-L-dT-CE Phosphoramidite; 5'-Dimethoxytrityl-beta-L-2'-deoxyThymidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5'-O-DMTr-L-dT-3'-CED phosphoramidite. Grade: ≥95%. CAS No. 141846-55-1. Molecular formula: C40H49N4O8P. Mole weight: 744.83. | |
| 5'-O-DMTr-N2-iBu-2'-L-deoxyguanosine 3'-CE phosphoramidite | 5'-O-DMTr-N2-iBu-2'-L-deoxyguanosine 3'-CE phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. The 5'-O-DMTr group is a protective group at the 5' position of the nucleoside, which prevents unwanted reactions during synthesis and can be removed afterward. The N2-iBu modification attaches an isobutyl group to the N2 position of the guanine base, which alters its physical properties, such as hydrophobicity or stability. The 2'-L-deoxy indicates that the sugar is a 2'-deoxyribonucleotide with an L-enantiomer configuration, often used to enhance the stability or biological activity of the oligonucleotide. The 3'-CE phosphoramidite refers to a cyanoethyl group protecting the 3' phosphoramidite group, which is essential for the chemical ligation of nucleotides during oligonucleotide synthesis. This phosphoramidite is useful for synthesizing stable, modified DNA oligonucleotides with specific properties for research or therapeutic applications. Synonyms: N-[9-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-L-erythro-pentofuranosyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-2-methylpropanamide; Phosphoramidous acid, bis(1-methylethyl)-, mono(2-cyanoethyl) ester, ester with N-[9-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-β-L-erythro-pentofuranosyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-2-methylpropana. | |
| 5'(R)-Me-T amidite | 5'-O-DMTr-5'(R)-C-methyl-thymidine 3'-CED phosphoramidite is a modified phosphoramidite used in DNA synthesis. It is particularly useful for synthesizing DNA oligonucleotides with enhanced stability and resistance to degradation. It can be employed in molecular biology, diagnostics, and therapeutic applications where modified DNA sequences are needed for specific functions, such as gene editing, diagnostics, or drug development. Synonyms: 5'-O-DMTr-5'(R)-C-methyl-thymidine 3'-CED phosphoramidite; 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2,6-dideoxy-β-D-ribo-hexofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; 5'(R)-Me-dT amidite. Grade: ≥97%. CAS No. 167934-48-7. Molecular formula: C41H51N4O8P. Mole weight: 758.84. | |
| 5'(S)-Me-T amidite | 5'(S)-Me-T amidite is a modified phosphoramidite used in DNA synthesis. It is particularly useful for synthesizing DNA oligonucleotides with enhanced stability and resistance to degradation. It can be employed in molecular biology, diagnostics, and therapeutic applications where modified DNA sequences are needed for specific functions, such as gene editing, diagnostics, or drug development. Synonyms: 5'-O-DMTr-5'(S)-C-methyl-thymidine 3'-CED phosphoramidite; 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2,6-dideoxy-α-L-lyxo-hexofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; 5'(S)-Me-dT amidite. Grade: ≥97%. CAS No. 167934-49-8. Molecular formula: C41H51N4O8P. Mole weight: 758.84. | |
| 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-CE phosphoramidite | The 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-beta-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-CE phosphoramidite has been proven effective against cancer. Synonyms: 5'-O-DMT-2'-fluoro-N2-isobutyryl-2'-arabinofuranosyl-deoxyguanosine 3'-CE phosphoramidite; 2'-F-2'-ara-N2-ibu-dG phosphoramidite; Propanamide, N-[9-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-2-methyl-; N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-fluoro-2'-arabinoguanosine-3'-CED-phosphoramidite; 9-{5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl}-2-(isobutyrylamino)-1,9-dihydro-6H-purin-6-one. Grade: ≥97% by HPLC. CAS No. 1404463-20-2. Molecular formula: C44H53FN7O8P. Mole weight: 857.93. | |
| A(Ac)-TOM-CE Phosphoramidite | 2'-O-TOM-A(Ac) Phosphoramidite is a specialized reagent used in oligonucleotide synthesis. It features a 2'-O-TOM (2'-O-tomc) modification attached to an adenosine (A) nucleotide, along with an acetyl (Ac) group. This modification enhances stability and protects against nuclease degradation. It is often employed in applications such as RNA interference, gene expression modulation, and therapeutic RNA-based treatments. The synthesis of RNA using monomers containing the 2'-O-Triisopropylsilyloxymethyl (TOM) group (TOM-Protecting-Group) has very high coupling efficiency along with fast, simple deprotection. Synonyms: 5'-Dimethoxytrityl-N-acetyl-Adenosine, 2'-O-triisopropylsilyloxymethyl-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N-Acetyl-2'-O-[(triisopropylsilyloxy)methyl]-3'-O-[diisopropylamino(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)adenosine; Adenosine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[[[tris(1-methylethyl)silyl]oxy]methyl]-, 3'-[2-cyanoethyl N,N-bis(1-methyleth. Grade: ≥95%. CAS No. 253586-13-9. Molecular formula: C52H72N7O9PSi. Mole weight: 998.23. | |
| Ac-dC-PACE Phosphoramidite | Ac-dC-PACE Phosphoramidite, a vital instrument in the construction of oligonucleotides for eradicating viral infections and cancer, operates as a foundation for modified nucleic acid analogs, which specialize in pinpointing particular RNA or DNA sequences within the body. With its distinctive chemical makeup, it has the ability to stifle the spread of viruses and impede the progression of tumors, rendering it an auspicious nomination within the realm of biomedicine. Synonyms: DNA C(Ac) PACE amidite; Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[P-[2-(2-cyano-1,1-dimethylethoxy)-2-oxoethyl]-N,N-bis(1-methylethyl)phosphonamidite]; dC(Ac)-PACE Phosphoramidite; 5'-Dimethoxytrityl-N-acetyl-2'-deoxyCytidine, 3'-O-(N,N-diisopropylamino)-phosphinyl-1,1-dimethyl-2-cyanoethyl acetate; N-Acetyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-[(bisisopropylamino)(2-cyano-1,1-dimethylethoxycarbonylmethyl)phosphino]-2'-deoxycytidine. Grade: ≥95%. CAS No. 411234-22-5. Molecular formula: C45H56N5O9P. Mole weight: 841.93. | |
| Amino-Modifier C6 dC | Amino-Modifier C6 dC is designed for automatic synthesis. During oligonucleotide synthesis, the addition of the amino modifier dC can replace the dC residue to functionalize the target oligonucleotide. Synonyms: Amino-modifier-C6-dC Phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-N-[(dimethylamino)methylene]-5-[(1E)-3-oxo-3-({6-[(trifluoroacetyl)amino]hexyl}amino)-1-propen-1-yl]cytidine; 5'-Dimethoxytrityl-N-dimethylformamidine-5-[N-(trifluoroacetylaminohexyl)-3-acrylimido]-2'-deoxycytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Amino-Modifier C6 dC CEP; Amino-modifier-C6-dC-CE-Phosphoramidite; Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-[(dimethylamino)methylene]-5-[3-oxo-3-[[6-[(trifluoroacetyl)amino]hexyl]amino]-1-propenyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]. Grade: ≥95%. CAS No. 853955-92-7. Molecular formula: C53H68F3N8O9P. Mole weight: 1049.12. | |
| Amino-Modifier C6 dT | Amino-Modifier C6 dT is a pivotal aspect, serving as a prized instrument for conducting comprehensive nucleic acid investigations. This extraordinary compound has played a crucial role in augmenting the realm of pharmaceutical transport mechanisms and diagnostic apparatuses. Synonyms: Amino-modifier C6 dT CE Phosphoramidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-[(1E)-3-oxo-3-[[6-[(2,2,2-trifluoroacetyl)amino]hexyl]amino]-1-propen-1-yl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-5-[(1E)-3-oxo-3-({6-[(trifluoroacetyl)amino]hexyl}amino)-1-propen-1-yl]uridine; Amino-modifier C6 dT Phosphoramidite; Amino-Modifier C6 dT CEP. Grade: 95%. CAS No. 210534-16-0. Molecular formula: C50H62F3N6O10P. Mole weight: 995.03. | |
| AP-dC Phosphoramidite | AP-dC Phosphoramidite is a modified cytidine phosphoramidite used in oligonucleotide synthesis. AP stands for an abasic protection group on the cytosine base, which means the standard cytosine base is absent or replaced with a protecting group, creating an abasic site. This modification is typically used in studies involving DNA damage, repair mechanisms, or the creation of oligonucleotides with specific lesions for biochemical and biophysical analyses. The phosphoramidite group at the 3' position enables its incorporation into oligonucleotide chains during solid-phase synthesis. AP-dC Phosphoramidite is valuable for generating site-specific abasic modifications in DNA to investigate structural and functional aspects of nucleic acids. Synonyms: N-[2-[[3-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-2,3-dihydro-2-oxo-1H-pyrimido[5,4-b][1,4]benzoxazin-9-yl]oxy]ethyl]-2,2,2-trifluoroacetamide; DNA C-clamp (TFA); 1-[5'-O-(4,4'-Dimethoxytrityl)-β-D-2'-deoxyribofuranosyl]-9-(2-trifluoroacetamidoethoxy)-1,3-diaza-2-oxophenoxazine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; AP-dC-CE Phosphoramidite. Grade: ≥97%. CAS No. 1360536-91-9. Molecular formula: C49H54F3N6O10P. Mole weight: 974.96. | |
| Beta-D-homoDNA-C(Bz) Phosphoramidite | Beta-D-homoDNA C(Bz) Phosphoramidite is a reagent used in the synthesis of oligonucleotides containing modified nucleotides known as beta-D-homoDNA, where the sugar backbone is altered to include an additional carbon atom, leading to an extended structure compared to regular DNA. This specific phosphoramidite incorporates a cytosine (C) base with a benzoyl (Bz) protecting group on the exocyclic amino group, which helps prevent undesired reactions during synthesis. The modification in the sugar backbone (beta-D-homoDNA) provides increased stability and unique binding properties, making it valuable for applications in molecular biology, diagnostics, and therapeutic research. Synonyms: Benzamide, N-[1-[6-O-[bis(4-methoxyphenyl)phenylmethyl]-4-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2,3-dideoxy-β-D-erythro-hexopyranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-, (S)-; Phosphoramidous acid, bis(1-methylethyl)-, mono(2-cyanoethyl) ester, ester with N-[1-[6-O-[bis(4-methoxyphenyl)phenylmethyl]-2,3-dideoxy-β-D-erythro-hexopyranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]benzamide, (S)-; (2R,3S,6R)-6-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydro-2H-pyran-3-yl (2-cyanoethyl) (S)-diisopropylphosphoramidite. Grade: ≥98%. CAS No. 145610-77-1. Molecular formula: C47H54N5O8P. Mole weight: 847.94. | |
| dA(Bz)-PACE Phosphoramidite | dA-PACE Phosphoramidite is a crucial reagent utilized in the development of oligonucleotide therapeutics for treating various genetic disorders such as cystic fibrosis and Huntington's disease. The unique PACE (phosphoramidite conjugated to aminohexylCE) modification improves the pharmacokinetic properties of the resulting oligonucleotide drugs, allowing for enhanced cellular uptake and longer half-life in the body. Synonyms: dA-PACE Phosphoramidite; 5'-Dimethoxytrityl-N-benzoyl-2'-deoxyAdenosine, 3'-O-(N,N-diisopropylamino)-phosphinyl-1,1-dimethyl-2-cyanoethyl acetate; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[P-[2-(2-cyano-1,1-dimethylethoxy)-2-oxoethyl]-N,N-bis(1-methylethyl)phosphonamidite]; DNA A(Bz) PACE amidite. Grade: ≥95%. CAS No. 411234-24-7. Molecular formula: C51H58N7O8P. Mole weight: 928.02. | |
| dG(iBu)-PACE Phosphoramidite | dG-PACE Phosphoramidite is a key reagent in the biomedical industry used for the synthesis of oligonucleotides. It contains a modified nucleotide base that facilitates the detection of SNP mutations associated with diseases such as cancer and cystic fibrosis. Its use in site-specific labeling of DNA strands has also been found useful in gene expression studies. Synonyms: DNA G(iBu) PACE amidite; dG-PACE Phosphoramidite; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(2-methyl-1-oxopropyl)-, 3'-[P-[2-(2-cyano-1,1-dimethylethoxy)-2-oxoethyl]-N,N-bis(1-methylethyl)phosphonamidite]; 5'-Dimethoxytrityl-N-isobutyryl-2'-deoxyguanosine, 3'-O-(N,N-diisopropylamino)-phosphinyl-1,1-dimethyl-2-cyanoethyl acetate. Grade: ≥95%. CAS No. 411234-26-9. Molecular formula: C48H60N7O9P. Mole weight: 910.01. | |
| Dichloro{(S)-(-)-5,5-bis[di(3,5-xylyl)phosphino]-4,4-bi-1,3-benzodioxole}[(2S)-(+)-1,1-bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine]ruthenium(II)rucl2[(S)-dm-segphos][(S)-daipen] | Dichloro{(S)-(-)-5,5-bis[di(3,5-xylyl)phosphino]-4,4-bi-1,3-benzodioxole}[(2S)-(+)-1,1-bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine]ruthenium(II)rucl2[(S)-dm-segphos][(S)-daipen]. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 944450-44-6, Dichloro[(S)-(-)-5,5 inverted exclamation marka-bis[di(3,5-xylyl)phosphino]-4.4 inverted exclamation marka-bi-1,3-benzodioxole][(2S)-(+)-1,1-bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine]ruthenium(II). Product Category: Heterocyclic Organic Compound. CAS No. 944450-44-6. Molecular formula: C65H70Cl2N2O6P2Ru. Mole weight: 1209.18. Purity: 0.96. IUPACName: [4-[5-bis(3,5-dimethylphenyl)phosphanyl-1,3-benzodioxol-4-yl]-1,3-benzodioxol-5-yl]-bis(3,5-dimethylphenyl)phosphane;(2S)-1,1-bis(4-methoxyphenyl)-3-methylbutane-1,2-diamine;dichlororuthenium. Product ID: ACM944450446. Alfa Chemistry ISO 9001:2015 Certified. | |
| DMT-2'-O-4'-C Locked-Tr-CE Phosphoramidite | DMT-2'-O-4'-C Locked-Tr-CE Phosphoramidite is a phosphoramidite compound used for the synthesis of locked nucleic acids (LNAs). This molecule is derived from a nucleoside and features several key modifications: a dimethoxytrityl (DMT) group at the 5' position, a 2'-O-4'-C methylene bridge (creating a locked ribose conformation), and a cyanoethyl (CE) phosphoramidite group for incorporation into oligonucleotides. DMT-2'-O-4'-C Locked-Tr-CE Phosphoramidite is valuable in various applications, including antisense therapy, siRNA, miRNA research, and diagnostic assays. The enhanced stability and binding properties of LNA-modified oligonucleotides make them powerful tools in molecular biology and medical research, providing greater specificity and efficacy in targeting RNA or DNA sequences. Synonyms: DMTr-LNA-5MeU-3-CED-phosphoramidite; 5'-O-DMT-2'-O,4'-C-methylene-5-methyluridine 3'-CE-phosphoramidite; 5'-O-(4,4'-dimethoxytrityl)-2'-O-4'-C-Locked-thymidine-3'-cyanoethyl Phosphoramidite; 1-[2,5-Anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-α-L-lyxofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; 5'-O-(4,4'-Dimethoxytrityl)-LNA-thymidine-3'-cyanoethyl phosphoramidite; DMT-locT Amidite; LNA-T phosphoramidite. Grade: ≥98% by HPLC. CAS No. 206055-75-6. Molecular formula: C41H49N4O9P. Mole weight: 772.84. | |
| DMTr-dH2U-amidite | DMTr-dH2U-amidite is an invaluable entity, emerging prominently due to its indispensability in the synthesis of nucleotide analogs and customized oligonucleotides. It assumes a pivotal function in the advancement of pharmaceuticals designed to study an array of ailments, ranging from cancer to viral infections and genetic anomalies. Synonyms: 2-Deoxy-2'-deoxy-5'-(4,4'-dimethoxytrityl)uridine-3'-CED phosphoramidite; 4(1H)-Pyrimidinone, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-. Grade: ≥95%. CAS No. 151503-28-5. Molecular formula: C39H47N4O7P. Mole weight: 714.79. | |
| dT-PACE Phosphoramidite | dT-PACE Phosphoramidite is a vital constituent within the biomedical arena, serving as a pivotal recompound solely dedicated to the solid-phase synthesis of oligonucleotides. Proficiently facilitating the assimilation of dT-PACE is a distinctly altered nucleoside analog, into the intricate framework of oligonucleotide chains. Synonyms: DNA T PACE amidite; Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[P-[2-(2-cyano-1,1-dimethylethoxy)-2-oxoethyl]-N,N-bis(1-methylethyl)phosphonamidite]; 5'-Dimethoxytrityl-2'-deoxyThymidine, 3'-O-(N,N-diisopropylamino)-phosphinyl-1,1-dimethyl-2-cyanoethyl acetate. Grade: ≥95%. CAS No. 411234-18-9. Molecular formula: C44H55N4O9P. Mole weight: 814.90. | |
| DyLight 3.5 CEP | DyLight 3.5 CEP is a fluorescent dye used for oligonucleotide labeling. Synonyms: Cy3.5 Phosphoramidite; 1H-Benz[e]indolium, 2-[3-[3-[3-[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]propyl]-1,3-dihydro-1,1-dimethyl-2H-benz[e]indol-2-ylidene]-1-propen-1-yl]-3-[3-[(4-methoxyphenyl)diphenylmethoxy]propyl]-1,1-dimethyl-, chloride (1:1); Cy 3.5 Phosphoramidite; Cyanine 3.5 Phosphoramidite; 1-[3-(4-monomethoxy)propyl]-1'-[3 -[(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite]propyl]-3,3,3',3'-Tetramethyl-4,5-benzoindolecyanine chloride. Grade: ≥85.0%. CAS No. 916753-57-6. Molecular formula: C66H74ClN4O4P. Mole weight: 1053.74. | |
| Ferrocene-dT CE Phosphoramidite | Ferrocene-dT CE Phosphoramidite is a specialized reagent for solid-phase oligonucleotide synthesis, enabling site-specific incorporation of a ferrocene moiety at the 5-position of deoxythymidine (dT). The ferrocene group acts as a redox-active reporter, facilitating electrochemical detection and analysis of DNA hybridization and interactions. This modification does not disrupt natural base-pairing or hybridization behavior, allowing multiple incorporations into a single oligonucleotide probe for enhanced signal amplification. It is widely used in electrochemical biosensors, molecular diagnostics, and DNA-mediated charge transfer studies. Synonyms: Ferrocene-dT Phosphoramidite; [2-[[6-[[(2E)-3-[1-[(2R,4S,5R)-5-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-4-[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]tetrahydro-2-furanyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinyl]-1-oxo-2-propen-1-yl]amino]hexyl]amino]-2-oxoethyl]ferrocene. Grade: ≥95%. CAS No. 2698331-21-2. Molecular formula: C60H73FeN6O10P. Mole weight: 1125.07. | |
| Fluorescein 2'-deoxy-5'-O-DMT-pseudouridine 3'-CE phosphoramidite | It is a remarkable compound showcasing its unparalleled potency in targeting and studying a wide range of (mention the specific diseases) through its unique mechanism of action. Synonyms: Propanoic acid, 2,2-dimethyl-, 5-[[[6-[[3-[5-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl]-1-oxo-2-propenyl]amino]hexyl]amino]carbonyl]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl ester; Fluorescein-deoxy-pU Phosphoramidite; Fluorescein 5-methyl-2'-deoxy-5'-O-DMT-pseudouridine 3'-CE phosphoramidite; 6-Fluorescein 5-methyl-2'-deoxy-5'-O-DMT-pseudouridine 3'-CE phosphoramidite. Grade: ≥95%. CAS No. 289712-99-8. Molecular formula: C79H89N6O17P. Mole weight: 1425.57. | |
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