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A novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells. Group: Biochemicals. Alternative Names: 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile; SKI 606. Grades: Highly Purified. CAS No. 380843-75-4. Pack Sizes: 5mg, 10mg, 50mg. US Biological Life Sciences.
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Bosutinib
Bosutinib is an orally active Src/Abl tyrosine kinase inhibitor with IC 50 of 1.2 nM and 1 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKI-606. CAS No. 380843-75-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10158.
Bosutinib
Bosutinib (SKI-606) is a novel, dual Src/Abl inhibitor with IC50 of 1.2 nM and 1 nM, respectively. Synonyms: SKI606; SKI 606; SK-I606. Bosutinib; Brand name: Bosulif. Grades: >98%. CAS No. 380843-75-4. Molecular formula: C26H29Cl2N5O3. Mole weight: 530.45.
Bosutinib-d8
A novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells. This is the labeled analog. Group: Biochemicals. Alternative Names: 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile-d8; SKI 606-d8. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Bosutinib hydrate
Bosutinib hydrate is an oraly activel Src/Abl tyrosine kinase inhibito with IC 50 of 1.2 nM and 1 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKI-606 hydrate. CAS No. 918639-08-4. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10158A.
Bosutinib Isomer
Bosutinib Isomer is an isomer of Bosutinib. Synonyms: 4-[(3,5-Dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile; Bosutinib isomer 4; PF-06651481; PF-06651481-00. Grades: > 95%. CAS No. 1391063-17-4. Molecular formula: C26H29Cl2N5O3. Mole weight: 530.46.
Bosutinib Isomer Methanoate
Bosutinib Isomer is the 3,5-dichloro-4-methoxy isomer of Bosutinib. It has been reported that this compound has been offered incorrectly as Bosutinib (B676095) C&E News 90 (21) 2012 34-35 and Levinson NM, Boxer SG (2012) Structural and Spectroscopic Analysis of the Kinase Inhibitor Bosutinib and an Isomer of Bosutinib Binding to the Abl Tyrosine Kinase Domain. PLoS ONE 7(4): e29828. doi:10. 1371/journal. pone. 0029828. Group: Biochemicals. Alternative Names: 4-[(3,5-Dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile Methanoate. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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Bosutinib methanoate
Bosutinib methanoate. Group: Biochemicals. Alternative Names: 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile methanoate; SKI 606 methanoate. Grades: Highly Purified. CAS No. 918639-10-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C27H33Cl2N5O4. US Biological Life Sciences.
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1-Methyl-4-propylpiperazine Bosutinib
1-Methyl-4-propylpiperazine Bosutinib. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS00251. Format: Neat.
5,6-Dihydroxy-Des(dimethoxy) Bosutinib
5,6-Dihydroxy-Des(dimethoxy) Bosutinib. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS00515. Format: Neat.
2-Cyano-N-(3,5-dichloro-4-methoxyphenyl)-acetamide is the impurity of the drug Bosutinib (B676095), which is a novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells. It is related to 4-[(3,5-Dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile (D435380). Group: Biochemicals. Grades: Highly Purified. CAS No. 1821033-10-6. Pack Sizes: 10mg, 25mg. Molecular Formula: C10H8Cl2N2O2, Molecular Weight: 259.089999999999. US Biological Life Sciences.
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