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| Product | Description | |
|---|---|---|
| Brefeldin a | Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus. Brefeldin A is also an autophagy and mitophagy inhibitor. Brefeldin A is a CRISPR/Cas9 activator. Brefeldin A inhibits HSV-1 and has anti-cancer activity. Group: Inhibitors. Alternative Names: NECTROLIDE; SYNERGISIDIN; 4h-cyclopent(f)oxacyclotridecin-4-one, 1, 6, 7, 8, 9, 11a-beta, 12, 13, 14, 14a-alpha-de; cahydro-1-beta-13-alpha-dihydroxy-6-beta-methyl-; cyanaein; CYANEIN; DECUMBIN; GAMMA-4-DIHDYROXY-2-(6-HYDROXY-1-HEPTENYL)-4-CYCLOPENTANECROTONIC ACID LAMBDA-LACTONE. CAS No. 20350-15-6. Molecular formula: C16H24O4. Mole weight: 280.36. Purity: 0.9987. Catalog: ACM20350156. |  |
| Brefeldin A | 10mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C16H24O4. CAS No. 20350-15-6. Prepack ID 17689223-10mg. Molecular Weight 280.36. See USA prepack pricing. |  |
| Brefeldin A | Brefeldin A (BFA) is a fungal metabolite demonstrated to reversibly interfere with anterograde transport from the endoplasmic reticulumto the Golgi apparatus (1,2). While initially isolated as an antibiotic (3), and does have a wide range of antibiotic activity, it is primarily used as a biological research tool for studying protein transport. Treatment leads to a rapid accumulation of proteins within the ER and collapse of the Golgi stacks. Treatment with BFA can also inhibit protein secretion (4) and prolonged exposure can induce apoptosis (5). The main target of BFA appears to be ADP-ribosylation factor (ARF), which is responsible for association of coat protein to the Golgi membrane (6,7). Group: Biochemicals. Alternative Names: gamma-4-Dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid lambda -lactone; Ascotoxin; BFA; Cyanein; Decumbin;g-4-Dihdyroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic Acid, ?-Lactone, BFA; Cyanein; Decumbin; Synergisidin; Nectrolide. Grades: Purified. CAS No. 20350-15-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C16H24O4, Molecular Weight: 280.36. US Biological Life Sciences. |  Worldwide |
| Brefeldin A | Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus [1] [2]. Brefeldin A is also an autophagy and mitophagy inhibitor [3]. Brefeldin A is a CRISPR/Cas9 activator [5]. Brefeldin A inhibits HSV-1 and has anti-cancer activity [5]. Uses: Scientific research. Group: Natural products. Alternative Names: BFA; Cyanein; Decumbin. CAS No. 20350-15-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16592. |  |
| Brefeldin B | Brefeldin is an antibiotic produced by Penicillum brefeldianum S-464, Pen. cyaneum S-ll, Pen. decumbens, Pen. simplicissimum S-544, etc. Molecular formula: C15H22O4. Mole weight: 266.33. |  |
| Brefeldin C | Brefeldin is an antibiotic produced by Penicillum brefeldianum S-464, Pen. cyaneum S-ll, Pen. decumbens, Pen. simplicissimum S-545, etc. Synonyms: (1S,2Z,7S,10Z,12R,13R)-12-hydroxy-7-methyl-8-oxabicyclo[11.3.0]hexadeca-2,10-dien-9-one; 4H-Cyclopent(f)oxacyclotridecin-4-one, 1,6,7,8,9,11a,12,13,14,14a-decahydro-1-hydroxy-6-methyl-, (1R-(1R*,2E,6S*,10E,11aS*,14aR*))-. Grades: 95%. CAS No. 73899-78-2. Molecular formula: C16H24O3. Mole weight: 264.36. | |
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