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| Product | Description | |
|---|---|---|
| Brexpiprazole | Brexpiprazole is a novel atypical antipsychotic drug. It is a D2 dopamine partial agonist called serotonin-dopamine activity modulator (SDAM). It is a drug candidate useful in treatment and prevention of mental disorders including CNS disorders. Uses: Brexpiprazole is approved for the treatment of schizophrenia, and as an adjunctive treatment for depression. it is a drug candidate useful in treatment and prevention of mental disorders including cns disorders. Synonyms: 7-[4-(4-(Benzo[b]thien-4-yl)-piperazin-1-yl)butoxy]-1H-quinolin-2-one; OPC 34712. Grade: > 95%. CAS No. 913611-97-9. Molecular formula: C25H27N3O2S. Mole weight: 433.58. |  |
| Brexpiprazole | Brexpiprazole (OPC-34712), an atypical orally active antipsychotic agent, is a partial agonist of human 5-HT1A and dopamine D 2L receptor with K i s of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a K i of 0.47 nM. Brexpiprazole also shows potent antagonist activity at human noradrenergic α 1B (K i =0.17 nM) and α 2C receptors (K i =0.59 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OPC-34712. CAS No. 913611-97-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-15780. |  |
| Brexpiprazole-d8-1 | Brexpiprazole-d 8 -1 (OPC-34712-d 8 -1) is the deuterium labeled Brexpiprazole (HY-15780) [1]. Brexpiprazole (OPC-34712), an atypical orally active antipsychotic agent, is a partial agonist of human 5-HT1A and dopamine D 2L receptor with K i s of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a K i of 0.47 nM. Brexpiprazole also shows potent antagonist activity at human noradrenergic α1B ( K i =0.17 nM) and α2C receptors ( K i =0.59 nM) [2] [3]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: OPC-34712-d8-1. CAS No. 1427049-19-1. Pack Sizes: 500 μg; 1 mg. Product ID: HY-15780S1. | |
| Brexpiprazole dihydrochloride | The hydrochloride salt form of Brexpiprazole, whihch is a D2 dopamine partial agonist called serotonin-dopamine activity modulator (SDAM). Brexpiprazole exhibits high affinity for h5-HT1A (partial agonist), h5-HT2A (antagonist), hD2L (partial agonist), hα1B (antagonist) and hα2C-adrenergic (antagonist) receptors (Ki values <1 nM). Synonyms: OPC 34712 dihydrochloride; 7-(4-(4-(benzo[b]thiophen-4-yl)piperazin-1-yl)butoxy)quinolin-2(1H)-one dihydrochloride. Grade: 98%. CAS No. 2512192-75-3. Molecular formula: C25H27N3O2S.2HCl. Mole weight: 506.49. | |
| Brexpiprazole hydrochloride | The hydrochloride salt form of Brexpiprazole, whihch is a D2 dopamine partial agonist called serotonin-dopamine activity modulator (SDAM). Brexpiprazole exhibits high affinity for h5-HT1A (partial agonist), h5-HT2A (antagonist), hD2L (partial agonist), hα1B (antagonist) and hα2C-adrenergic (antagonist) receptors (Ki values <1 nM). Synonyms: 7-[4-(4-benzo[b]thien-4-yl-1-piperazinyl)butoxy]-2(1H)-Quinolinone hydrochloride; 7-[4-[4-(1-Benzothiophen-4-yl)piperazin-1-yl]butoxy]-1H-quinolin-2-one hydrochloride. Grade: 98%. CAS No. 913612-38-1. Molecular formula: C25H27N3O2S.xHCl. Mole weight: 433.58 (free base). | |
| Brexpiprazole Impurity 10 | Brexpiprazole Impurity 10 is an impurity of Brexpiprazole, a drug used to counter psychiatric afflictions such as schizophrenia and major depressive disorder. Synonyms: m-Cinnamanisidide; N-(3-Methoxyphenyl)-3-phenylpropenamide. Grade: > 95%. CAS No. 15116-41-3. Molecular formula: C16H15NO2. Mole weight: 253.30. | |
| Brexpiprazole Impurity 10 | Brexpiprazole Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 15116-41-3. Molecular formula: C16H15NO2. Mole weight: 253.3. Catalog: APB15116413. |  |
| Brexpiprazole Impurity 20 | Brexpiprazole Impurity 20. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(benzofuran-4-yl)piperazine. CAS No. 105685-34-5. Molecular formula: C12H14N2O. Mole weight: 202.25. Catalog: APB105685345. | |
| Brexpiprazole Impurity 38 | Brexpiprazole Impurity 38. Uses: For analytical and research use. Group: Impurity standards. CAS No. 102-92-1. Molecular formula: C9H7ClO. Mole weight: 166.6. Catalog: APB102921. | |
| Brexpiprazole Impurity 39 | Brexpiprazole Impurity 39. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(benzo[b]thiophen-7-yl)piperazine. CAS No. 105685-06-1. Molecular formula: C12H14N2S. Mole weight: 218.32. Catalog: APB105685061. | |
| Brexpiprazole Impurity 40 | Brexpiprazole Impurity 40. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(piperazin-1-yl)benzo[b]thiophene-2-carboxylic acid. CAS No. 1700655-67-9. Molecular formula: C13H14N2O2S. Mole weight: 262.33. Catalog: APB1700655679. | |
| Brexpiprazole Impurity 48 | Brexpiprazole Impurity 48. Uses: For analytical and research use. Group: Impurity standards. CAS No. 105684-85-3. Molecular formula: C12H15ClN2O. Mole weight: 238.72. Catalog: APB105684853. | |
| Brexpiprazole Impurity 75 | Brexpiprazole Impurity 75. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(benzo[b]thiophen-4-yl)piperazine-1-carbaldehyde. CAS No. 1677681-04-7. Molecular formula: C13H14N2OS. Mole weight: 246.33. Catalog: APB1677681047. | |
| Brexpiprazole Impurity 76 | Brexpiprazole Impurity 76. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(4-(benzo[b]thiophen-4-yl)piperazin-1-yl)ethanone. CAS No. 1700655-62-4. Molecular formula: C14H16N2OS. Mole weight: 260.35. Catalog: APB1700655624. | |
| Brexpiprazole Impurity 9 | Brexpiprazole Impurity 9 is an impurity of brexpiprazole and related pharmaceutical formulations. Brexpiprazole is a medication utilized to treat schizophrenia and major depressive disorder. Synonyms: 5-Hydroxyquinolin-2(1H)-one; 5-Hydroxy-2(1H)-quinolone; 5-Hydroxycarbostyril; NSC 134652. Grade: > 95%. CAS No. 31570-97-5. Molecular formula: C9H7NO2. Mole weight: 161.16. | |
| Brexpiprazole-[piperazin-d8] | Brexpiprazole-[piperazin-d8] is the labelled analogue of Brexpiprazole. Brexpiprazole is a partial agonist of dopamine D2 receptor used as an atypical antipsychotic. It was approved by FDA for the treatment of schizophrenia. Synonyms: Brexpiprazole-piperazin-D8; 7-[4-(4-(Benzo[b]thien-4-yl)-piperazin-1-yl)butoxy]-1H-quinolin-2-one-d8; Brexpiprazole-d8; 7-[4-[4-(1-Benzothiophen-4-yl)-2,2,3,3,5,5,6,6-d8-piperazin-1-yl]butoxy]-1H-quinolin-2-one. Grade: >95%. CAS No. 1427049-21-5. Molecular formula: C25H19D8N3O2S. Mole weight: 441.63. | |
| Brexpiprazole S-oxide | Brexpiprazole S-oxide is a main metabolite of Brexpiprazole and is metabolized by cytochrome P450 3A4 (CYP3A4). Brexpiprazole is an atypical antipsychotic agent and a partial agonist of human 5-HT1A and dopamine receptor. Synonyms: DM-3411; 7-[4-[4-(1-Oxidobenzo[b]thien-4-yl)-1-piperazinyl]butoxy]-2(1H)-quinolinone; 4-(4-{4-[(2-Oxo-1,2-dihydro-7-quinolinyl)oxy]butyl}-1-piperazinyl)-1-benzothiophenium-1-olate. Grade: ≥95%. CAS No. 1191900-51-2. Molecular formula: C25H27N3O3S. Mole weight: 449.57. | |
| 1-[2-(Benzothiophen-4-yl)benzothiophen-4-yl]piperazine | 1-[2-(Benzothiophen-4-yl)benzothiophen-4-yl]piperazine is an impurity of Brexpiprazole (B677385), which is a drug candidate useful in treatment and prevention of mental disorders including CNS disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 2126178-14-9. Pack Sizes: 25mg, 100mg. Molecular Formula: C20H20Cl2N2S2, Molecular Weight: 423.42. US Biological Life Sciences. |  Worldwide |
| 1-(4-(4-(Benzo[b]thiophen-4-yl)piperazin-1-yl)butyl)-7-(4-((2-oxo-1,2-dihydroquinolin-7-yl)oxy)butoxy)quinolin-2(1H)-one | 1-(4-(4-(Benzo[b]thiophen-4-yl)piperazin-1-yl)butyl)-7-(4-((2-oxo-1,2-dihydroquinolin-7-yl)oxy)butoxy)quinolin-2(1H)-one is Brexpiprazole (B677385) impurity. Brexpiprazole is an antipsychotic drug and antidepressant for major depressive disorders (MDD). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C38H40N4O4S, Molecular Weight: 648.809999999999. US Biological Life Sciences. | Worldwide |
| 1,4-Bis(benzo[b]thien-4-yl)piperazine | 1,4-Bis(benzo[b]thien-4-yl)piperazine is a Brexpiprazole impurity (B677385). Brexpiprazole is a drug candidate useful in treatment and prevention of mental disorders including CNS disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 1420987-86-5. Pack Sizes: 10mg, 25mg. Molecular Formula: C20H18N2S2, Molecular Weight: 350.5. US Biological Life Sciences. | Worldwide |
| 1-(Benzothiophen-4-yl)-4-[4-[4-(benzothiophen-4-yl)piperazin-1-yl]butyl]piperazine | 1-(Benzothiophen-4-yl)-4-[4-[4-(benzothiophen-4-yl)piperazin-1-yl]butyl]piperazine is an impurity of Brexpiprazole (B677385), which is a drug candidate useful in treatment and prevention of mental disorders including CNS disorders. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. Molecular Formula: C28H34N4S2, Molecular Weight: 490.73. US Biological Life Sciences. | Worldwide |
| 7-(4-Chlorobutoxy)-1-(4-chlorobutyl)quinolin-2-one | An impurity of Brexpiprazole, a dopamine D2 partial agonist used as an atypical antipsychotic drug. Brexpiprazole has been approved for the treatment of schizophrenia. Synonyms: 7-(4-chlorobutoxy)-1-(4-chlorobutyl)quinolin-2(1H)-one. CAS No. 2059954-32-2. Molecular formula: C17H21Cl2NO2. Mole weight: 342.26. | |
| 7-(4-Chlorobutoxy)quinolin-2(1H)-one | An impurity of Brexpiprazole, a dopamine D2 partial agonist used as an atypical antipsychotic drug. Brexpiprazole has been approved for the treatment of schizophrenia. Synonyms: 7-(4-chlorobutoxy)-1H-quinolin-2-one; 2(1H)-Quinolinone,7-(4-chlorobutoxy)-. CAS No. 913613-82-8. Molecular formula: C13H14ClNO2. Mole weight: 251.71. | |
| 7-(4-hydroxybutoxy)quinolin-2(1H)-one | An impurity of Brexpiprazole, a dopamine D2 partial agonist used as an atypical antipsychotic drug. Brexpiprazole has been approved for the treatment of schizophrenia. Synonyms: 7-(4-Hydroxybutoxy)-2(1H)-quinolinone; Brexpiprazole Impurity 7. CAS No. 1886188-97-1. Molecular formula: C13H15NO3. Mole weight: 233.26. | |
| 7,7'-[(1,4-Butanediyl)bis(oxy)]bis-2(1H)quinolinone | An impurity of Brexpiprazole, a dopamine D2 partial agonist used as an atypical antipsychotic drug. Brexpiprazole has been approved for the treatment of schizophrenia. Synonyms: Brexpiprazole Impurity-12. CAS No. 2116542-19-7. Molecular formula: C22H20N2O4. Mole weight: 376.41. | |
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