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c-diGMP is a bacterial second messenger and a STING ligand. Synonyms: 3'-Guanylic acid, guanylyl-(3'→5')-, cyclic nucleotide; 5GP-5GP; Cyclic di-3',5'-guanylate; Cyclic diguanylate; Cyclic diguanylate monophosphate; Cyclic-di-GMP; cGpGp; Cyclic diguanylic acid; cdiGMP; 3',5'-Cyclic diguanylic acid; c-(Gpgp); Bis(3',5')-cyclic diguanylic acid. Grade: ≥95%. CAS No. 61093-23-0. Molecular formula: C20H24N10O14P2. Mole weight: 690.41.
c-di-GMP Fluorinated
A STING agonist. CAS No. 1334145-18-4. Molecular formula: C20H20F2N10O12P2.2Na. Mole weight: 738.36.
Cyclic-di-GMP diammonium
Cyclic di-GMP diammonium is a STING activator and a global bacterial second messenger, which regulates biofilm formation, motility, and virulence in diverse bacterial species. Synonyms: c-di-GMP diammonium; cyclic diguanylate diammonium; 5GP-5GP diammonium. Grade: 98%. CAS No. 609343-82-0. Molecular formula: C20H30N12O14P2. Mole weight: 724.47.
Cyclic-di-GMP disodium
Cyclic-di-GMP disodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP disodium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP disodium can be used in cancer research[1][2][3][4]. Uses: Scientific research. Group: Natural products. Alternative Names: c-di-GMP disodium; cyclic diguanylate disodium; 5GP-5GP disodium. CAS No. 2222132-40-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-110382.
Cyclic-di-GMP sodium
Cyclic di-GMP sodium is a STING activator and a global bacterial second messenger, which regulates biofilm formation, motility, and virulence in diverse bacterial species. Synonyms: c-di-GMP sodium; cyclic diguanylate sodium; 5GP-5GP sodium. Molecular formula: C20H24N10O14P2.xNa.
Cyclic di-GMP disodium salt
Cyclic di-GMP is a second messenger in bacteria, which is involved in diverse prokaryotic processes, including biofilm formation, motility, virulence, and cell cycling. Cyclic di-GMP induces expression of IFN-β mRNA in vitro (EC50 = 537.8 nM) but less potently than 2'3'-cGAMP, 3'2'-cGAMP, 3'3'-cGAMP, and 2'2'-cGAMP. Synonyms: Cyclic-di-GMP.Na2; 3'-Guanylic acid, guanylyl-(3'→5')-, cyclic nucleotide, disodium salt; 5GP-5GP disodium salt; Cyclic di-3',5'-guanylate disodium salt; Cyclic diguanylate disodium salt; Cyclic diguanylate monophosphate disodium salt; Cyclic-di-GMP disodium salt; cGpGp disodium salt; Cyclic diguanylic acid disodium salt; cdiGMP disodium salt; 3',5'-Cyclic diguanylic acid; disodium salt c-(Gpgp) disodium salt; Bis(3',5')-cyclic diguanylic acid disodium salt; Cyclic di-GMP sodium salt; c-di-GMP disodium salt. Grade: ≥95%. CAS No. 2222132-40-1. Molecular formula: C20H22N10Na2O14P2. Mole weight: 734.37.
Cyclic diguanosine monophosphate
Cyclic diguanosine monophosphate. Group: Biochemicals. Alternative Names: C-di-GMP; Cyclic-di-GMP; Cyclic bis (3',5') diguanylic acid; Cyclic diguanylate. Grades: Highly Purified. CAS No. 61093-23-0. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C20H24N10O14P2. US Biological Life Sciences.
Worldwide
cyclic-guanylate-specific phosphodiesterase
Requires Mg2+ or Mn2+ for activity and is inhibited by Ca2+ and Zn2+. Contains a heme unit. This enzyme linearizes cyclic di-3,5-guanylate, the product of EC 2.7.7.65, diguanylate cyclase and an allosteric activator of EC 2.4.1.12, cellulose synthase (UDP-forming), rendering it inactive. It is the balance between these two enzymes that determines the cellular level of c-di-GMP. Group: Enzymes. Synonyms: cyclic bis(3?5')diguanylate phosphodiesterase; c-di-GMP-specific phosphodiesterase; c-di-GMP phosphodiesterase; phosphodiesterase (misleading); phosphodiesterase A1; PDEA1; VieA. Enzyme Commission Number: EC 3.1.4.52. CAS No. 338732-46-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3735; cyclic-guanylate-specific phosphodiesterase; EC 3.1.4.52; 338732-46-0; cyclic bis(3?5')diguanylate phosphodiesterase; c-di-GMP-specific phosphodiesterase; c-di-GMP phosphodiesterase; phosphodiesterase (misleading); phosphodiesterase A1; PDEA1; VieA. Cat No: EXWM-3735.
D(+)-Raffinose pentahydrate
D(+)-Raffinose pentahydrate is an orally active inhibitor of LecA ( K d = 32 μM) and GtfC. D(+)-Raffinose pentahydrate reduces cyclic diguanylate (c-di-GMP) by increased activity of a c-di-GMP specific phosphodiesterase. D(+)-Raffinose pentahydrate interferes with GTF function. D(+)-Raffinose pentahydrate decreases IL-4 and IL-5 mRNA. D(+)-Raffinose pentahydrate exhibits biofilm-inhibitory activity against Pseudomonas aeruginosa and Streptococcus mutans and inhibits allergic airway eosinophilia [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: D-Raffinose pentahydrate. CAS No. 17629-30-0. Pack Sizes: 10 mM * 1 mL; 5 g. Product ID: HY-N1938.
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