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| Product | Description | |
|---|---|---|
| C646 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopyenzyme activators, inhibitors & substrates. |  |
| C646 | C646 is an inhibitor for histone acetyltransferase, and inhibits p300 with a Ki of 400 nM. Preferentially selective for p300 versus other acetyltransferases. Synonyms: C646; C-646; C 646. Grades: >98%. CAS No. 328968-36-1. Molecular formula: C24H19N3O6. Mole weight: 445.42. |  |
| C646 | C646 is a selective and competitive histone acetyltransferase p300 inhibitor with Ki of 400 nM, and is less potent for other acetyltransferases[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 328968-36-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg; 50 mg; 100 mg. Product ID: HY-13823. |  |
| C646 | Reversible cell permeable p300/CBP histone acetyltransferase (HAT) inhibitor. Specific inhibition to p300 (86%) compared to N-acetyltransferase, PCAF, GCN5, Rtt109, Sas or MOZ histone acetyltransferases (<10%). Cell growth inhibitor in melanoma and non-small-cell-lung (NSCL) human cancer cell lines. Group: Biochemicals. Alternative Names: (E)-4-(4-((5-(4,5-Dimethyl-2-nitrophenyl)furan-2-yl)-methylene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid. Grades: Highly Purified. CAS No. 328968-36-1. Pack Sizes: 1mg, 5mg. Molecular Formula: C24H19N3O6. US Biological Life Sciences. |  Worldwide |
| Histone Acetyltransferase p300 Inhibitor, C646 | Histone Acetyltransferase p300 Inhibitor, C646, CAS 328968-36-1, is a cell-permeable, reversible inhibitor of p300/CBP HAT (Ki = 400 nM). Competes with acetyl-CoA for the p300 Lys-CoA binding pocket. Group: Fluorescence/luminescence spectroscopy. | |
| Daratumumab | Daratumumab is a recombinant IgG1k monoclonal antibody that binds to CD38 and leads to cell apoptosis. Daratumumab was granted orphan drug designation for the treatment of multiple myeloma, diffuse large B cell lymphoma, follicular lymphoma, and mantle cell lymphoma. Uses: Antitumor agent. Synonyms: Darzalex; HuMax-CD38; UNII-4Z63YK6E0E. CAS No. 945721-28-8. Molecular formula: C6466H9996N1724O2010S42. Mole weight: 145391.67. | |
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