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Calcein. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g. US Biological Life Sciences.
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Calcein
Calcein is a fluorescent dye and self-quenching probe, used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. Calcein can also be used as a model drug for evaluating efficiency and bioavailability of drug delivery systems [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Fluorexon. CAS No. 1461-15-0. Pack Sizes: 100 mg. Product ID: HY-D0040.
Calcein AM
Calcein AM. Group: Biochemicals. Grades: Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Calcein-AM
Calcein AM, has cell membrane permeability and can easily enter the cell. Calcein AM has no fluorescence and is hydrolyzed by endogenous esterase in the cell to produce polar molecule Calcein (Calcein), which has strong negative charge and cannot permeate the cell membrane. Calcein can emit strong green fluorescence, so it is often used with Propidium Iodide for cell viability/virulence detection, excitation/emission wavelength: 494/515 nm [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Calcein acetoxymethyl ester. CAS No. 148504-34-1. Pack Sizes: 1 mg. Product ID: HY-D0041.
Calcein Blue
Calcein Blue, a membrane-impermeant fluorescent dye, is a coumarin derivative that contains an iminodiacetic acid structure. Calcein Blue is also a metallofluorochromic indicator [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 54375-47-2. Pack Sizes: 10 mM * 1 mL; 25 mg. Product ID: HY-101887.
Calcein Blue AM
Calcein Blue AM is a cellular dye agent [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 168482-84-6. Pack Sizes: 1 mg (2.15 mM * 1 mL in DMSO). Product ID: HY-124298.
CP 100356 is a high affinity P-glycoprotein inhibitor.Ki value is 58 nM for mouse Pgp1a and 94nMfor Pgp1b isoforms. It can Inhibit calcein-AM uptake in MDR1-transfected MDCKII cells with IC50 value of 0.5 μM and prazosin transport in BCRP-transfected MDCKII cells with IC50 value of 1.5 μM. Preclinical development for Cancer in USA was discontinued. Uses: Cancer. Synonyms: CP 100356; CP100356; CP-100356; 4-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-N-(2-(3,4-dimethoxyphenyl)ethyl)-6,7-dimethoxy-2-Quinazolinamine; 142715-48-8(hydrochloride). Grades: >98 %. CAS No. 142716-85-6. Molecular formula: C31H36N4O6. Mole weight: 560.64.
Fluorexon
Fluorexon is used in the synthesis of vesicles for drug containment and delivery. Also used in liposome-based drug delivery involving antitumor ether lipids. Group: Biochemicals. Alternative Names: N, N'-[ (3', 6'-dihydroxy-3-oxospiro[isobenzofuran-1 (3H) , 9'-[9H]xanthene]-ar', ar'-diyl) bis (methylene) ]bis[N- (carboxymethyl) glycine; Calcein; Fluorescein Complexon. Grades: Highly Purified. CAS No. 154071-48-4. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
Poloxamer 407 (F127)
Poloxamer 407 (F127) is a nonionic surfactant that is 100% active and relatively non-toxic to cells at low concentrations, and frequently used with dye AM esters such as Indo-1 AM, Fura-2 AM, Calcein AM, Fluo-3 AM, Fluo-4 AM, Quest Fluo-8 AM and Quest Rhod-4 AM, etc. to improve their water solubility. Poloxamer 407 is also a lipoprotein lipase inhibitor [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: PEG-PPG-PEG, 12600 (Average Mn). CAS No. 9003-11-6. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-D1005.
(S)-Verapamil hydrochloride
(S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-(-)-Verapamil hydrochloride. CAS No. 36622-28-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-135336A.
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