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| Product | Description | |
|---|---|---|
| Calcimycin | Calcimycin (A-23187) is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin induces Ca2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin induces apoptosis[1][2][3][4]. Uses: Scientific research. Group: Natural products. Alternative Names: A-23187; Antibiotic A-23187. CAS No. 52665-69-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-N6687. |  |
| Calcimycin | Calcimycin is an antibiotic produced by Streptomyces chartreusis. It has weak anti-gram-positive bacteria, negative bacteria and fungi activity. It can form stable complexes with divalent cations and exhibit ionophore effects. It is also used as a fluorescent reagent for detecting the hydrophilicity of proteins and as a coupling agent for oxidative phosphorylation. Synonyms: A-23187. Grades: >99% by HPLC. CAS No. 52665-69-7. Molecular formula: C29H37N3O6. Mole weight: 523.62. |  |
| Antibiotic A23187 (Calcimycin, Calcium Ionophore A23187) | Antibiotic A23187 is a calcium ionophore. It causes rapid influx of calcium in various cells across biological membranes. Calcimycin was isolated from Streptomyces chartreusis in 1974. Calcimycin is a spiroketal substituted by pyrollic and benzoxazolyl groups which afford its high affinity and selectivity for calcium. Calimycin exhibits broad biological activity against bacteria, fungi and protozoa. It has found wide application as a research tool for calcium regulated cellular events. Group: Biochemicals. Alternative Names: Calcimycin, Calcium Ionophore A23187. Grades: Molecular Biology Grade. CAS No. 52665-69-7. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C29H37N3O6, Molecular Weight: 523.6. US Biological Life Sciences. |  Worldwide |
| 4-Bromo-A23187 | 4-Bromo-calcimycin, a halogenated analog of A-2318, is a non-fluorescent Ca2+ ionophore which could be commonly used in fluorescent probes experiments as a modutor of the quantitation of free Ca2+. Nonfluorescent calcium ionophore used as a calibration standard for determining cytoplasmic calcium ions by fluorescent probes. Synonyms: A23187, 4-Bromo; 4-Bromocalcimycin; 4-Benzoxazolecarboxylic acid. Grades: ≥98%. CAS No. 76455-48-6. Molecular formula: C29H36BrN3O6. Mole weight: 602.50. | |
| A23187 Ca-Mg | A23187 Ca-Mg, the calcium-magnesium salt of A23187, has been found to be a Ca2+ ionophore and shows pro-inflammatory and allergic activities. Uses: Used in cell activation experiments when calcium dose-response data are not required. Synonyms: Calcimycin calcium magnesium salt; Antibiotic A23187 calcium magnesium salt; Ionophore A23187 calcium magnesium salt. Grades: ≥99%. Molecular formula: (C29H36N3O6)2Mg.(C29H36N3O6)2Ca. Mole weight: 2154.87. | |
| Calcium ionophore a23187 hemimagnesium salt | Calcium ionophore a23187 hemimagnesium salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Calcimycin hemimagnesium salt, Calcium Ionophore A23187 hemimagnesium salt, Calimycin hemimagnesium salt, A23187 hemimagnesium salt, C9400_SIGMA, Antibiotic A 23187 hemimagnesium salt, 72124-77-7. Product Category: Heterocyclic Organic Compound. CAS No. 72124-77-7. Molecular formula: C29H36Mg0.5N3O6. Mole weight: 534.77. Purity: 0.96. IUPACName: magnesium;5-(methylamino)-2-[[(2S,3R,5R,6S,8R,9R)-3,5,9-trimethyl-2-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-8-yl]methyl]-1,3-benzoxazole-4-carboxylate. Canonical SMILES: CC1CCC2(C(CC(C(O2)C(C)C(=O)C3=CC=CN3)C)C)OC1CC4=NC5=C(O4)C=CC(=C5C(=O)[O-])NC.CC1CCC2(C(CC(C(O2)C(C)C(=O)C3=CC=CN3)C)C)OC1CC4=NC5=C(O4)C=CC(=C5C(=O)[O-])NC.[Mg+2]. Product ID: ACM72124777. Alfa Chemistry ISO 9001:2015 Certified. Categories: 635-340-4. |  |
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