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| Product | Description | |
|---|---|---|
| Ebselen | Ebselen (SPI-1005), a glutathione peroxidase mimetic, is a potent voltage-dependent calcium channel (VDCC) blocker [1] [2]. Ebselen potently inhibits M pro ( IC 50 =0.67 μM) and COVID-19 virus ( EC 50 =4.67 μM) [3].Ebselen is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen, an organoselenium compound, can permeate the blood-brain barrier and has anti-inflammatory, antioxidant and anticancer activity [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SPI-1005; PZ-51; CCG-39161. CAS No. 60940-34-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13750. |  |
| Ebselen | Ebselen (SPI-1005), a glutathione peroxidase mimetic, is a potent voltage-dependent calcium channel (VDCC) blocker. Ebselen potently inhibits Mpro (IC50=0.67 μM) and COVID-19 virus (EC50=4.67 μM).Ebselen is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen, an organoselenium compound, can permeate the blood-brain barrier and has anti-inflammatory, antioxidant and anticancer activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-phenyl-2-benzisoselenazol-3(2h)-one;PZ51;2-phenyl-benzo[d]isoselenazol-3-one;2-PHENYL-1,2-BENZISOSELENAZOL-3(2H)-ONE;EBSELEN;EBSELEN (PZ51, 2-PHENYL-1,2-BENZISOSELEN AZOL-3(2H)-ONE);EBSELEN 99%;2-phenyl-1,2-benzisoselenazol-. Product Category: Inhibitors. Appearance: light yellow solid. CAS No. 60940-34-3. Molecular formula: C13H9NOSe. Mole weight: 274.18. Purity: 0.96. IUPACName: 2-phenyl-1,2-benzoselenazol-3-one. Canonical SMILES: C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2. ECNumber: 612-054-8. Product ID: ACM60940343. Alfa Chemistry ISO 9001:2015 Certified. |  |
| MJ33 lithium salt | MJ33 is a selective and reversible inhibitor of the acidic, calcium-independent (ai)PLA2 activity of Prdx6. Prdx6 is a bifunctional enzyme with both non-selenium glutathione peroxidase (Gpx) and PLA2 activities. Synonyms: 1-Hexadecyl-3-(trifluoroethyl)-sn-glycero-2-phosphomethanol, Li. Grades: ≥95%. CAS No. 1007476-63-2. Molecular formula: C22H43F3LiO6P. Mole weight: 498.5. |  |
| myeloperoxidase | Contains calcium and covalently bound heme (proximal ligand histidine). It is present in phagosomes of neutrophils and monocytes, where the hypochlorite produced is strongly bactericidal. It differs from EC 1.11.1.10 chloride peroxidase in its preference for formation of hypochlorite over the chlorination of organic substrates under physiological conditions (pH 5-8). Hypochlorite in turn forms a number of antimicrobial products (Cl2, chloramines, hydroxyl radical, singlet oxygen). MPO also oxidizes bromide, iodide and thiocyanate. In the absence of halides, it oxidizes phenols and has a moderate peroxygenase activity toward styrene. Group: Enzymes. Synonyms: MPO; verdoperoxidase. Enzyme Commission Number: EC 1.11.2.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0513; myeloperoxidase; EC 1.11.2.2; MPO; verdoperoxidase. Cat No: EXWM-0513. |  |
| NAD(P)H oxidase (H2O2-forming) | Requires FAD, heme and calcium. When calcium is present, this transmembrane glycoprotein generates H2O2 by transfering electrons from intracellular NAD(P)H to extracellular molecular oxygen. The electron bridge within the enzyme contains one molecule of FAD and probably two heme groups. This flavoprotein is expressed at the apical membrane of thyrocytes, and provides H2O2 for the thyroid peroxidase-catalysed biosynthesis of thyroid hormones. Group: Enzymes. Synonyms: THOX2; ThOX; dual oxidase; p138tox; thyroid NADPH oxidase; thyroid oxidase; thyroid oxidase 2; NADPH oxidase; NAD(P)H:oxygen oxidoreductase; NAD(P)H oxidase. Enzyme Commission Number: EC 1.6.3.1. CAS No. 77106-92-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1583; NAD(P)H oxidase (H2O2-forming); EC 1.6.3.1; 77106-92-4; THOX2; ThOX; dual oxidase; p138tox; thyroid NADPH oxidase; thyroid oxidase; thyroid oxidase 2; NADPH oxidase; NAD(P)H:oxygen oxidoreductase; NAD(P)H oxidase. Cat No: EXWM-1583. | |
| Oxalyl Chloride | Oxalyl Chloride is used in the preparation of cardiolipin analogs which induce peroxidase activity by Cytochrome C. It is also used in the preparation of fluorescent indicators for cytosolic calcium. Group: Biochemicals. Alternative Names: Ethanedioyl Dichloride; Oxalic Acid Chloride; Oxalic Acid Dichloride; Oxalic Dichloride; Oxaloyl Chloride; Oxaloyl Dichloride; Oxalyl Dichloride. Grades: Highly Purified. CAS No. 79-37-8. Pack Sizes: 50g. US Biological Life Sciences. |  Worldwide |
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