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| Product | Description | |
|---|---|---|
| calpain-1 | In peptidase family C2. Requires Ca2+ at micromolar concentrations for activity. Cytosolic in animal cells. The active enzyme molecule is a heterodimer in which the large subunit contains the peptidase unit, and the small subunit is also a component of EC 3.4.22.53, calpain-2. Group: Enzymes. Synonyms: μ-calpain; calcium-activated neutral protease I. Enzyme Commission Number: EC 3.4.22.52. CAS No. 78990-62-2. Calpain 1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4227; calpain-1; EC 3.4.22.52; 78990-62-2; μ-calpain; calcium-activated neutral protease I. Cat No: EXWM-4227. |  |
| Calpain 1 human | aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. |  |
| Calpain-1, Human Erythrocytes | Calpain-1, Human Erythrocytes, is a native calpain-1. A heterodimeric cysteine proteinase with low Ca2+ requirement (EC?? = 2 μM). Group: Fluorescence/luminescence spectroscopy. | |
| Calpain-1, Porcine Erythrocytes | Calpain-1, Porcine Erythrocytes, is a native calpain-1. A heterodimeric cysteine proteinase with low Ca2+ requirement (EC?? = 2 μM). Group: Fluorescence/luminescence spectroscopy. | |
| calpain-2 | Type example of peptidase family C2. Requires Ca2+ at millimolar concentrations for activity. Cytosolic in animal cells. The active enzyme molecule is a heterodimer in which the large subunit contains the peptidase unit, and the small subunit is also a component of EC 3.4.22.52, calpain-1. Group: Enzymes. Synonyms: calcium-activated neutral protease II; m-calpain; milli-calpain. Enzyme Commission Number: EC 3.4.22.53. CAS No. 702693-80-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4228; calpain-2; EC 3.4.22.53; 702693-80-9; calcium-activated neutral protease II; m-calpain; milli-calpain. Cat No: EXWM-4228. | |
| calpain-3 | This Ca2+-dependent enzyme is found in skeletal muscle and is genetically linked to limb girdle muscular dystrophy type 2A. The enzyme is activated by autoproteolytic cleavage of insertion sequence 1 (IS1),which allows substrates and inhibitors gain access to the active site. Substrates include the protein itself and connectin/titin. Belongs in peptidase family C2. Group: Enzymes. Synonyms: p94; calpain p94; CAPN3; muscle calpain;calpain 3; calcium-activated neutral proteinase 3; muscle-specific calcium-activated neutral protease 3; CANP 3; calpain L3. Enzyme Commission Number: EC 3.4.22.54. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4229; calpain-3; EC 3.4.22.54; p94; calpain p94; CAPN3; muscle calpain;calpain 3; calcium-activated neutral proteinase 3; muscle-specific calcium-activated neutral protease 3; CANP 3; calpain L3. Cat No: EXWM-4229. | |
| Calpain inhibitor I | Calpain inhibitor I. Group: Biochemicals. Grades: Highly Purified. CAS No. 110044-82-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C20H37N3O4. US Biological Life Sciences. |  Worldwide |
| Calpain Inhibitor I | ?97% (TLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| Calpain Inhibitor I | MG-101, also known as Calpain Inhibitor I and ALLN, is a calpain inhibitor (IC50 = 0.09 μM) that activates p53-dependent apoptosis in tumor cell lines. Activities of MG-101 includes: (1) reduce colon injury caused by dinitrobenzene sulphonic acid, (2) overcome acquired resistance to TRAIL, (3) protect against atractyloside-induced toxicity. (4). reduce colon injury caused by dinitrobenzene sulphonic acid. Synonyms: (S)-N-Acetyl-L-leucyl-N-(1-formylpentyl)-L-leucinamide; ALLN; ALLnL; CI-1 (peptide); Calp I; Calpain inhibitor I; MG 101; (S)-N-Acetyl-L-leucinyl-L-leucinyl-L-norleucinal; MG-101. Grades: 98 %. CAS No. 110044-82-1. Molecular formula: C20H37N3O4. Mole weight: 383.52. |  |
| Calpain Inhibitor II | Calpain Inhibitor II. Group: Biochemicals. Grades: Highly Purified. CAS No. 110115-07-6. Pack Sizes: 5mg, 10mg, 25mg. US Biological Life Sciences. | Worldwide |
| Calpain Inhibitor II | Calpain inhibitor II is a cell-permeable inhibitor of calpain I (Ki = 120 nM), calpain II (Ki = 230 nM), cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 600 pM). It inhibits activation-induced programmed cell death and restores defective immune responses in HIV+ donors. Calpain inhibitor II can block nitric oxide production by interfering with transcription of the inducible nitric oxide synthase gene, which is a weak inhibitor of proteasome. It has been used to demonstrate the involvement of ubiquitin-proteasome protein degradation in various biological systems. Uses: Cysteine proteinase inhibitors. Synonyms: L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-1-formyl-3-(methylthio)propyl]-; L-Leucinamide, N-acetyl-L-leucyl-N-[1-formyl-3-(methylthio)propyl]-, (S)-; N-Acetyl-L-leucyl-N-[(1S)-1-formyl-3-(methylthio)propyl]-L-leucinamide; ALLM; Calp II; CI 2; SUAM 312; N-acetylleucyl-leucyl-methioninal; Ac-Leu-Leu-Met-al; N-acetyl-L-leucyl-L-leucyl-L-methioninal. Grades: ≥98%. CAS No. 110115-07-6. Molecular formula: C19H35N3O4S. Mole weight: 401.57. | |
| Calpain Inhibitor II | powder. Group: Fluorescence/luminescence spectroscopy. | |
| Calpain Inhibitor III | Calpain Inhibitor III. Group: Biochemicals. Grades: Highly Purified. CAS No. 88191-84-8. Pack Sizes: 25mg, 50mg, 100mg. US Biological Life Sciences. | Worldwide |
| Calpain Inhibitor III - CAS 88191-84-8 | The Calpain Inhibitor III, also referenced under CAS 88191-84-8, controls the biological activity of Calpain. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy. | |
| Calpain Inhibitor IV | The Calpain Inhibitor IV controls the biological activity of Calpain. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy. | |
| Calpain Inhibitor V | The Calpain Inhibitor V controls the biological activity of Calpain. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy. | |
| Calpain Inhibitor VI | Calpain Inhibitor VI is a cell-permeable peptide aldehyde which functions as a reversible calpain inhibitor. It is an inhibitor of the calcium-dependent cysteine proteases μ-calpain with IC50 of 7.5 nM for calpain-1 and m-calpain with IC50 of 78 nM for calpain-2. Calpain Inhibitor VI can reduce nuclear opacity and proteolysis of crystallins and α-spectrin. It also prevents cataract formation induced by selenite in rats when administered at a dose of 100 mg/kg for 4 days. Synonyms: SJA 6017. Grades: ≥95%. CAS No. 190274-53-4. Molecular formula: C17H25FN2O4S. Mole weight: 372.5. | |
| Calpain Inhibitor VI - CAS 190274-53-4 | The Calpain Inhibitor VI, also referenced under CAS 190274-53-4, controls the biological activity of Calpain. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy. | |
| Calpain Inhibitor XI - CAS 145731-49-3 | The Calpain Inhibitor XI, also referenced under CAS 145731-49-3, controls the biological activity of Calpain. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy. | |
| Calpain Inhibitor XII | Calpain Inhibitor XII is a cell-permeable, potent, selective, reversible, and active-site-directed inhibitor of calpain-1 with Ki of 19 nM. It has been shown to inhibit calpain-2 with Ki of 120 nM and human cathepsin B with Ki of 750 nM. Calpain inhibitor XII has been used to study the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury. Synonyms: Z-L-Nva-CONH-CH2-2-Py. Grades: ≥90%. CAS No. 181769-57-3. Molecular formula: C26H34N4O5. Mole weight: 482.6. | |
| Anti-Calpain-10 (Domain T, N-Terminal), Large Subunit antibody produced in rabbit | ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Calpain-13 (Domain III, N-Terminal), Large Subunit antibody produced in rabbit | ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Calpain-13 (Domain I, N-Terminal), Large Subunit antibody produced in rabbit | ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Calpain-2, Large Subunit antibody produced in rabbit | 1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Calpain-5 (Domain III), Large Subunit antibody produced in rabbit | ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Calpain-5 (Domain II), Large Subunit antibody produced in rabbit | ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Calpain-5 (Domain I, N-Terminal), Large Subunit antibody produced in rabbit | ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Calpain-5 (Domain IV, C-Terminal), Large Subunit antibody produced in rabbit | ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Calpain-7 (Domain I, C-Terminal), Large Subunit antibody produced in rabbit | ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Calpain-7 (Domain III, C-Terminal), Large Subunit antibody produced in rabbit | ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Calpain-7 (Domain I, N-Terminal), Large Subunit antibody produced in rabbit | ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Calpain-7 (Domain N, C-Terminal), Large Subunit antibody produced in rabbit | ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Calpain-94 (Catalytic Domain), Large Subunit antibody produced in rabbit | ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Calpain-94 (Domain II), Large Subunit antibody produced in rabbit | ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Calpain-9 (Domain II, Catalytic Domain), Large Subunit antibody produced in rabbit | ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Calpain-9 (Domain I), Large Subunit antibody produced in rabbit | ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Calpain-9 (Domain IV, C-Terminal), Large Subunit antibody produced in rabbit | ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Calpain-9 (Domain IV) (EF-1), Large Subunit antibody produced in rabbit | ~1 mg/mL, affinity isolated antibody. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Calpain LP-82/LP-85 (Lens-Specific Calpain) (Domain III), Large Subunit antibody produced in rabbit | ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Calpain LP-85 (Lens-Specific Calpain) (Domain IV), Large Subunit antibody produced in rabbit | ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| MDL 28170, Z-Val-Phe-CHO, (Carbobenzoxy-valinyl-phenylalaninal, Calpain Inhibitor III) | A potent, cell-permeable, and selective inhibitor of calpain and cathepsin B (Ki values are 10 and 25nm respectively). MDL 28170 does not inhibit trypsin-like serine proteases. Rapidly penetrates the blood-brain barrier following systemic administration and displays neuroprotective effects in vivo. Modulates the formation of Ab formation by inhibiting the formation of intermediate Ab46 and protecting Ab from degradation. Group: Biochemicals. Grades: Highly Purified. CAS No. 88191-84-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Monoclonal Anti-?-Calpain (Calpain I, subunit p80) antibody produced in mouse | clone 15C10, purified immunoglobulin, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-?-Calpain (Domain II) antibody produced in mouse | clone 2H2A7C2, ascites fluid. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-?-Calpain (Domain III) antibody produced in mouse | clone 9A4H8D3, ascites fluid, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-?-Calpain, Large Subunit antibody produced in mouse | clone 15C10, purified immunoglobulin. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-m-Calpain (Domain III/IV) antibody produced in mouse | clone 107-82, ascites fluid. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-m/? Calpain, Small Subunit antibody produced in mouse | ~1 mg/mL, clone 28F3, purified immunoglobulin, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Native Human Calpain 1 | Caplain 1 is a neutral calcium-dependent cysteine protease containing the EF-hand motif. The protease consists of two subunits; the larger subunit has four domains that are homologous with papain and calmodulin. The smaller subunit has one domain that shares homology with calmodulin. It is activated by micromolar levels of calcium and hence, it is also called as micro-calpain. Its activation leads to cellular protein degradation, neuronal cell degeneRation, and autoimmune demyelinating diseases such as multiple sclerosis. > 95% (sds-page). Applications: Human calpain 1 has been used in a study to assess how the crystal structures of human calpains 1 and 9 imply diverse mechanisms of action and auto-inhibition. human calpain 1 has also been used in a study to investigate the synthesis, biological evaluation and molecular modelling of n-heterocyclic dipeptide aldehydes as selective calpain inhibitors. Group: Enzymes. Synonyms: calpain 1, μ-calpain; calcium-activated neutral protease I; EC 3.4.22.52. Enzyme Commission Number: EC 3.4.22.52. CAS No. 78990-62-2. Calpain 1. Storage: -70°C. Form: aqueous glycerol solution. Source: Human. calpain 1, μ-calpain; calcium-activated neutral protease I; EC 3.4.22.52. Cat No: NATE-0100. | |
| Native Porcine Calpain 1 | Caplain 1 is a neutral calcium-dependent cysteine protease containing the EF-hand motif. The protease consists of two subunits; the larger subunit has four domains that are homologous with papain and calmodulin. The smaller subunit has one domain that shares homology with calmodulin. It is activated by micromolar levels of calcium and hence, it is also called as micro-calpain. Its activation leads to cellular protein degradation, neuronal cell degeneRation, and autoimmune demyelinating diseases such as multiple sclerosis. Group: Enzymes. Synonyms: μ-calpain; calcium-activated neutral protease I; EC 3.4.22.52. Purity: > = 95% by SDS-PAGE. Calpain 1. Mole weight: 110000. Stability: > 1 year. Storage: -70°C or lower; avoid freeze/thaw cycles. Form: Frozen. Source: Porcine Erythrocytes. Species: Porcine. calpain 1, μ-calpain; calcium-activated neutral protease I; EC 3.4.22.52. Cat No: NATE-1625. | |
| 10-Undecenoic acid,98% (stabilized with TBC) | 10-Undecenoic acid (Undecylenic acid) is an antifungal agent. 10-Undecenoic acid inhibits Aβ oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid has neuroprotective effects. 10-Undecenoic acid has anticancer effects on a variety of tumors. 10-Undecenoic acid inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Natural products. Alternative Names: Undecylenic acid. CAS No. 112-38-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0914. |  |
| 10-Undecenoic acid (Standard) | 10-Undecenoic acid (Standard) is the analytical standard of 10-Undecenoic acid. This product is intended for research and analytical applications. 10-Undecenoic acid (Undecylenic acid) is an antifungal agent. 10-Undecenoic acid inhibits Aβ oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid has neuroprotective effects. 10-Undecenoic acid has anticancer effects on a variety of tumors. 10-Undecenoic acid inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Natural products. CAS No. 112-38-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B0914R. | |
| 12-Amino Minocycline | 12-Amino Minocycline is an impurity of Minocycline. It can be used in the preparation of calpain inhibitors. CAS No. 864073-42-7. Molecular formula: C23H28N4O6. Mole weight: 456.49. | |
| (2R,?3R)?-2-Bromo-3-hydroxybutanedioic Acid 1,4-Diethyl Ester | (2R,?3R)?-2-Bromo-3-hydroxybutanedioic Acid 1,4-Diethyl Ester is an intermediate in the synthesis of derivative of E-64 an inhibitor of cathepsins B and L as well as a potential inhibitor of calpain. Group: Biochemicals. Grades: Highly Purified. CAS No. 80640-15-9. Pack Sizes: 1g, 5g. Molecular Formula: C8H13BrO5. US Biological Life Sciences. | Worldwide |
| (2S, 3S) -3- [ [ [ (1S) -1- [ [ (4-Azidobutyl) amino] carbonyl] -3-methylbutyl] amino] carbonyl] -2-oxiranecarboxylic Acid Ethyl Ester | N3Le is a derivative of E-64 an inhibitor of cathepsins B and L as well as a potential inhibitor of calpain. E-64d has been shown to inhibit lysosomal proteases. Group: Biochemicals. Grades: Highly Purified. CAS No. 1174021-95-4. Pack Sizes: 1mg, 10mg. Molecular Formula: C16H27N5O5. US Biological Life Sciences. | Worldwide |
| 2-Thiophenebutanoic Acid | 2-Thiophenebutanoic Acid is used to prepare cell-penetrating peptide α-keto-amide calpain inhibitors as potential treatment for muscular dystrophy. it is also used to prepare isochroman carboxylic acid derivatives as potential anti-diabetic agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 4653-11-6. Pack Sizes: 1g, 5 g. Molecular Formula: C8H10O2S, Molecular Weight: 170.23. US Biological Life Sciences. | Worldwide |
| 3,3-Diphenylpropionic Acid | 3,3-Diphenylpropionic Acid is used in the preparation of steroid 5α-reductase inhibiting acylpiperidines. It can also be used in the preparation of calpain-inhibitory piptidyl α-ketoacids and esters. Group: Biochemicals. Alternative Names: β-Phenylbenzenepropanoic Acid; Diphenylpropionic Acid; NSC 631492; NSC 6797; β-Phenylbenzenepropanoic Acid. Grades: Highly Purified. CAS No. 606-83-7. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C??H??O?, Molecular Weight: 226.27. US Biological Life Sciences. | Worldwide |
| Acetyl-Calpastatin (184-210) (human) | Acetyl-Calpastatin (184-210) (human) is a calpain I/II inhibitor and could increase secretion of amyoid β-protein (Aβ) 42, Aβ40 and Aβ42 ratio. Grades: ≥95% by HPLC. CAS No. 123714-50-1. Molecular formula: C142H230N36O44S. Mole weight: 3177.65. | |
| Acetyl-Calpastatin(184-210)(human) | Acetyl-Calpastatin(184-210)(human) is a potent, selective and reversible calpain inhibitor with K i values of 0.2 nM and 6 μM for μ-calpain and cathepsin L, respectively [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 123714-50-1. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P1081. | |
| ALLM | ALLM (Calpain inhibitor II) is a potent inhibitor of calpain and cathepsin proteases. ALLM inhibits neuronal cell death and improves chronic neurological function after spinal cord injury (SCI) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Calpain inhibitor II. CAS No. 110115-07-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-118355. | |
| ALLM - CAS 110115-07-6 | Cell permeable inhibitor of calpain I (Ki = 120 nM), calpain II (Ki = 230 nM), cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 600 pM). Group: Fluorescence/luminescence spectroscopy. | |
| ALLN - CAS 110044-82-1 | Cell-permeable inhibitor of calpain I (Ki = 190 nM), calpain II (Ki = 220 nM), cathepsin B (Ki = 150 nM), and cathepsin L (Ki = 500 pM). Group: Fluorescence/luminescence spectroscopy. | |
| Aloxistatin | Aloxistatin is an inhibitor of cathepsins B and L as well as a potential inhibitor of calpain, which predicted to function against SARS-CoV-2 infection. Synonyms: L-trans-Epoxysuccinyl(OEt)-Leu-3-methylbutylamide; L-trans-Epoxysuccinyl-Leu-3-methylbutylamide-ethyl ester; (2S, 3S) -3-[[[ (1S) -3-Methyl-1-[[ (3-methylbutyl) amino]carbonyl]butyl]amino]carbonyl]-2-oxiranecarboxylic Acid Ethyl Ester; E 64c ethyl ester; E 64d; EP 453; EST; Loxistatin; NSC 694281; (2S,3S)-trans-Epoxysuccinyl-L-leucylamido-3-methylbutane ethyl ester. Grades: 98%. CAS No. 88321-09-9. Molecular formula: C17H30N2O5. Mole weight: 342.43. | |
| Aloxistatin (E-64d) | Aloxistatin (E-64d), is a selective cysteine protease inhibitor or calpain and autophagy inhibitor. E-64d prevents in vitro cerulein- induced trypsinogen activation. E-64d can enter the intact cell and inhibit calpain. E-64d has been shown safe for the treatment of Alzheimer's disease in human. E-64d is potentially useful in the treatment of developmental seizure-induced brain damage both by regulating abnormal zinc signal transduction and through the modulation of altered lipid metabolism via ApoE/clusterin pathway in hippocampus. Uses: Designed for use in research and industrial production. Additional or Alternative Names: E-64d; E 64d; E64d; E64-d; E64-d; E64 d; ethyl ester Loxistatin; NSC 694281; NSC694281; NSC-694281; EST; EP-453; EP453; EP 453; Aloxistatin. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 88321-09-9. Molecular formula: C17H30N2O5. Mole weight: 342.44. Purity: >98%. IUPACName: ethyl (2S,3S)-3-(((S)-1-(isopentylamino)-4-methyl-1-oxopentan-2-yl)carbamoyl)oxirane-2-carboxylate. Canonical SMILES: CCOC([C@@H]1[C@@H](C(N[C@H](C(NCCC(C)C)=O)CC(C)C)=O)O1)=O. Product ID: ACM88321099. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Aureusimine B | It is an inhibitor of the protease Calpain produced by the strain of Streptomyces sp. SC433. It is a small molecular weight monoketopiperazine formed non-ribosomally by the fusion of phenylalanine and valin. Synonyms: Phevalin; 3-(1-Methylethyl)-6-(phenylmethyl)-2(1H)-pyrazinone; 6-Benzyl-3-isopropylpyrazin-2-one. Grades: >95% by HPLC. CAS No. 170713-71-0. Molecular formula: C14H16N2O. Mole weight: 228.29. | |
| BAPTA-AM | BAPTA-AM is a lipophilic diester of BAPTA used for inhibition of proteolytic activities of certain metalloproteinases, calpain and TACE. Group: Biochemicals. Alternative Names: N,N'-[1,2-Ethanediylbis(oxy-2,1-phenylene)]bis[N-[2-[(acetyloxy)methoxy]-2-oxoethyl]glycine 1,1'-bis[(acetyloxy)methyl] ester; 1,2-Bis(2-aminophenoxy)ethane-N,N,N,N-tetraacetic acid tetraacetoxymethyl ester. Grades: Highly Purified. CAS No. 126150-97-8. Pack Sizes: 25mg, 50mg, 100mg. Molecular Formula: C??H??N?O??, Molecular Weight: 764.68. US Biological Life Sciences. | Worldwide |
| Biotin-LLY-FMK | Biotin-LLY-FMK is a biotin-labeled calpain inhibitor that can be used as a probe for detecting calpain II and cathepsin L by biotin ligand. Synonyms: Biotin-Leu-Leu-Tyr-Fluoromethylketone. Grades: ≥95%. Molecular formula: C32H48FN5O6S. Mole weight: 649.82. | |
| Calpastatin Peptide | A 27-amino acid, cell-permeable peptide encoded by exon 1B of human calpastatin that acts as a potent inhibitor of calpain I and calpain II (IC?? = 20 nM for purified rabbit calpain II). Group: Fluorescence/luminescence spectroscopy. | |
| Calpeptin | Calpeptin is a potent, cell penetrating calpain inhibitor, with an ID 50 of 40 nM for Calpain I in human platelets [1]. Calpeptin is also an inhibitor of cathepsin K [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 117591-20-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100223. | |
| Calpeptin | Calpeptin is a potent, cell-permeable calpain inhibitor with ID50 of 52 nM, 34 nM, 138 nM, and 40 nM for Calpain I (porcine erythrocytes), Calpain II (porcine kidney), Papainb, and Calpain I (human platelets), respectively. Uses: Cysteine proteinase inhibitors. Synonyms: Benzylcarbonyl-leu-nleu-H; Cbz-Leu-Nle-al. Grades: >98%. CAS No. 117591-20-5. Molecular formula: C20H30N2O4. Mole weight: 362.46. | |
| Calpeptin - CAS 117591-20-5 | A cell-permeable calpain inhibitor (ID?? = 52 nM for calpain-1; ID?? = 34 nM for calpain-2; ID?? = 138 nM for papain). Group: Fluorescence/luminescence spectroscopy. | |
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