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A unique collection of 1436 compounds with anti-breast cancer therapeutic activity or targeting breast cancers major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study?- Targets include HER-2, VEGF, EGFR, PARP, CDK4/6, HSP, PD-1, SET7/9, BRCA, etc. ?- Some compounds have been in market or in clinical trials; - Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2191. Categories: Anti-Breast Cancer Compounds Libraries.
Anti-Cancer Active Compound Library
A unique collection of 2114 compounds with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS); - Effective tool for molecular mechanism of tumorigenesis, and anti-tumor drug screening; - Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc. - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2160. Categories: Anti-Cancer Active Compounds Libraries.
Anti-Cancer Approved Drug Library
A unique collection of 1726 approved anti-cancer drugs for high throughput screening (HTS) and high content screening (HCS); - These FDA, EMA, or NMPA approved anti-cancer drugs have annotated bioactivity, safety, and bioavailability; - Effective tool for cancer research and drug repurposing screening; - Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc. , in lung cancer, breast cancer, leukemia, lymphoma, etc. - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2110. Categories: Anti-Cancer Approved Drug Libraries.
Anti-Cancer Clinical Compound Library
A unique collection of 1990 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS); - Bioactivity confirmed by pre-clinical research and all of them are currently in clinical trial phases, representing the cutting-edge treatments for cancers; - Effective tool for cancer research and drug repurposing screening; - Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc. , in lung cancer, breast cancer, leukemia, lymphoma, etc. - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2120. Categories: Anti-Cancer Clinical Compounds Libraries.
Anti-Cancer Compound Library
A unique collection of 5885 compounds with anti-cancer activity for high throughput screening (HTS) and high content screening (HCS); - Bioactivity and safety profiled in (confirmed by) pre-clinical and clinical settings (research and trials); - Effective tool for molecular mechanism of tumorigenesis, and anti-tumor drug screening; - Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc. - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2100. Categories: Anti-Cancer Compounds Libraries.
Anti-Cancer Drug Library
A unique collection of 2478 anticancer drugs for high throughput screening (HTS) and high content screening (HCS); - Bioactivity and safety profiled in (confirmed by) pre-clinical and clinical settings (research and trials), an effective tool for molecular mechanism of tumorigenesis, and anti-tumor drug repositioning drug discovery; - Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc; involved in 15 different cancer research areas, such as lung cancer, breast cancer, leukemia, lymphoma, etc. - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2150. Categories: Anti-Cancer Drug Libraries.
Anti-CancerLibrary Plus
Quantity: well-chosen 1468 anti-tumor compounds with unique structures; - High antitumor activity: 99% of compounds with IC50 below 3 μM; - Covers 42 tumor related targets with each compound having clear target; - Detailed information: each compound has information about activity testing method, providing reference for your experimental design; - HNMR/LCMS validated to ensure high purity and quality; - A supplemental tool for anticancer drug development and target identification. Uses: Scientific use. Product Category: L2180. Categories: Anti-Cancer Libraries Plus.
Anti-Cancer Metabolism Compound Library
A unique collection of 1280 cancer cellular metabolism related compounds for cancer research and high throughput screening (HTS) and high content screening (HCS); - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Covers 16 major targets related to cancer cellular metabolism (glucose, proteins, lipids and nucleic acids) including ACL, CA, FASN, GLUT, GLS, HMG-CoA, MAGL, MCTs, PDH, PDK, PKM, etc. ; Effect tool for research in cancer metabolism and anti-cancer drug screening. - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2130. Categories: Anti-Cancer Metabolism Compounds Libraries.
Anti-Lung Cancer Compound Library
A unique collection of 1566 compounds with anti-lung cancer therapeutic activity or targeting lung cancers major signaling pathways, can be used for anti-lung cancer drug discovery and mechanism study?- Targets include EGFR, PI3K, FGFR, HER2, ALK, c-Met, etc. ?- Some compounds have been in market or in clinical trials; - Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2190. Categories: Anti-Lung Cancer Compounds Libraries.
Anti-Pancreatic Cancer Compound Library
A unique collection of 1697 pancreatic cancer related compounds can be used in HTS and HCS. Uses: Scientific use. Product Category: L2192. Categories: Anti-Pancreatic Cancer Compounds Libraries.
Cancer Cell Differentiation Compound Library
A unique collection of 413 cancer cell differentiation inducing compounds for high throughput and high content screening; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2140. Categories: Cancer Cell Differentiation Compounds Libraries.
Approved Drug Library
A unique collection of 2863 approved drugs for high throughput screening (HTS) and high content screening (HCS); - All compounds collected in this library are drugs approved by Food and Drug Administration (FDA), the European Medicine Agency (EMA), or National Medical Products Administration (NMPA), etc; - An effective tool for discovering new with old drugs and new drug target identification; - Covers various research areas, such as Cancer, Cardiovascular disease, GPCR/G protein, Neuroscience, Membrane Transporter/Ion Channel, Microbiology & Virology, Immunology/Inflammation, Tyrosine Kinase/Adaptors, etc. - More detailed compound information with structure, target, activity, IC50 value, and brief introduction; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1000. Categories: Approved Drug Libraries.
CID-755673
CID-755673 is a selective protein kinase D (PKD) inhibitor. CID-755673 was identified from the National Institutes of Health small molecule repository library of 196,173 compounds. In cell-based assays, CID755673 blocked phorbol ester-induced endogenous PKD1 activation in LNCaP cells in a concentration-dependent manner. CID755673 inhibited prostate cancer cell proliferation, cell migration, and invasion. In summary, our findings indicate that CID755673 is a potent and selective PKD1 inhibitor with valuable pharmacological and cell biological potential. Synonyms: CID-755673; CID 755673; CID755673. Grades: 0.98. CAS No. 521937-07-5. Molecular formula: C12H11NO3. Mole weight: 217.224.
Drug Repurposing Compound Library
A unique collection of 4240 approved and clinical drugs for high throughput screening (HTS) and high content screening (HCS); - An effective tool for discovering new with old drugs, cell induction, and new drug target screening; - All approved drugs collected in this library are approved by Food and Drug Administration (FDA), the European Medicine Agency (EMA), or National Medical Products Administration (NMPA), or included in the US Pharmacopeia (USP) Dictionary, the British Pharmacopoeia (BP), the European Pharmacopoeia (EP), the Japanese Pharmacopoeia (JP), or Chinese Pharmacopoeia (CP) Dictionary; - Covers various research areas, such as cancer, cardiovascular disease, immunology, respiratory system, etc. - Covers various targets, such as 5-HT Receptor, Sodium Channel, p38 MAPK, PI3K, MEK, etc. - Detailed compound information with structure, target, activity, and brief introduction; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L9200. Categories: Drug Repurposing Compounds Libraries.
FDA-Approved & Pharmacopeia Drug Library
3158 compounds from marketed drugs for high throughput screening (HTS) and high content screening (HCS); - All compounds collected in this library are drugs approved by FDA, EMA, PMDA, NMPA, etc. or included in pharmacopoeia such as USP, BP, JP, etc. ; - An effective tool for discovering new with old drugs and new drug target identification; - Covers various research areas, such as Cancer, Cardiovascular disease, Neuroscience, Immunology/Inflammation, respiratory system disease, etc. - More detailed compound information with structure, target, activity, IC50 value, and brief introduction; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1010. Categories: FDA-Approved & Pharmacopeia Drug Libraries.
Anti-Tumor Natural Product Library
A unique collection of 1471 natural products with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS); - Known bioactivity for all compounds: detailed biological and pharmacological information, providing the research foundation and theoretical direction for screening; - Clear source: known active natural products selected from animals, plants, or microorganisms with clear species information; - Detailed compound information with structure, solubility, targeted signal pathways, action sites, and biological activity description; - Cost-effectiveness: expensive natural products with poor drug likeliness are excluded, allowing for more high-quality natural products at a lower cost. Uses: Scientific use. Product Category: L6700. Categories: Anti-Tumor Natural Product Libraries.
Apoptosis Compound Library
A unique collection of 1796 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening; - Targets include Bcl-2, Caspase, p53, TNF-alpha, and surviving, etc. ; - Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L9000. Categories: Apoptosis Compounds Libraries.
Bioactive Compound Library
A collection of 11585 small molecule compounds with validated activity for high throughput screening (HTS), high content screening (HCS), cell induction, and target identification; - All compounds have clear targets; - An effective tool for discovering new with old drugs, cell induction, and new drug target screening; - Covers various disease research areas, such as Cancer, Metabolism, Immunology and Cardiovascular system, etc. - Detailed compound information with structure, target, activity, IC50 value, and brief introduction; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L4000. Categories: Bioactive Compounds Libraries.
Bioactive Compounds Library Max
A collection of 19703 bioactive compounds for high-throughput screening, high-content screening, cell induction and target identification. - All compounds are described with corresponding target information, which makes activity studies more evidence-based. - An effective tool for drug repurposing and cell-induced target screening. - Covers multiple areas of disease studies, such as cancer, metabolism, immune system and cardiovascular system. - Detailed instructions, compound structures, target information, activity descriptions, etc. - Structural diversity, significant drug potency and cell penetration. Uses: Scientific use. Product Category: L4010. Categories: Bioactive Compounds Libraries Max.
Cell Cycle Compound Library
A unique collection of 695 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS); - Targets include CDK, ROCK, Aurora Kinase, ATM/ATR, DNA-PK, DNA/RNA Synthesis, etc. ; - Effective tool for research in cell cycle and related diseases, such as cancer, cardiovascular diseases, inflammation, neurodegenerative diseases, etc. ; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L8100. Categories: Cell Cycle Compounds Libraries.
Drug-induced Liver Injury (DILI) Compound Library
A unique collection of 1040 hepatotoxicity causing compounds, a powerful tool for drug toxicity study, can be used for HTS and HCS screening?- Include anti-cancer drugs, antibiotics, antituberculotic agents, antiretrovirals, antiepileptic agents, and cardiac medications, etc. ?- Diversified in toxicities: Steatosis, Mitochondrial toxicity, cholestasis, drug allergy (hypersensitivity), etc. ; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L5510. Categories: Drug-induced Liver Injury (DILI) Compounds Libraries.
Glutamine Metabolism Compound Library
A unique collection of 455 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and cancer; - Targets include glutaminase?GLS??ASCT2?glutamate dehydrogenase?c-Myc, etc. - Some compounds have been approved by the FDA; - Structurally diverse, medicinally active, and cell permeable; - Detailed compound information with structure, target, IC50 value, and bioactivity information; - NMR and HPLC/LCMS validated to ensure high purity. Uses: Scientific use. Product Category: L2550. Categories: Glutamine Metabolism Compounds Libraries.
HIF-1 Signaling Pathway Compound Library
A unique collection of 1352 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies?- Covers PI3K-AKT, MAPK, Ubiquitination signaling pathways and targets such as HIF, HIF Prolyl-Hydroxylase, E1/E2/E3 Enzyme, PI3K, MAPK, Proteasome, etc. - Part of them are in clinical trial phase or FDA approved?- Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L8500. Categories: HIF-1 Signaling Pathway Compounds Libraries.
Human Metabolite Library
A unique collection of 4532 human metabolites for high-throughput, high-content screening. - An effective tool for studying human metabolic diseases, exploring the pathogenesis of cancer and finding new drugs. - Some compounds have been marketed or entered the clinical phase, which ensured low bio-toxicity and high bio-activity. - Structural diversity, significant drug potency and cell permeability. - Detailed specifications, description of compound structures, activity, etc. - Various detection techniques such as NMR, HPLC/LCMS to ensure correct structure and high purity of the product and reduce false positives. Uses: Scientific use. Product Category: L2570. Categories: Human Metabolite Libraries.
Methylation Compound Library
125 methylation-related compounds that can be used for high-throughput and high-content screening. - Targets include DNA Methyltransferase, Histone Methyltransferase, etc. - Can be used for studies on epigenetics, differentiation, aging, cancer, etc. - Detailed instructions, compound structure, target information, activity description, etc. - NMR and HPLC analytical techniques to ensure high product purity and quality. - All compounds are available in stock. Uses: Scientific use. Product Category: L3510. Categories: Methylation Compounds Libraries.
NO PAINS Compound Library
9555 PAINS-excluded small molecules for high-throughput screening and high-content screening. - Diverse targets with wide coverage; covers multiple disease research areas such as cancer, metabolism, immune system and cardiovascular system. - An effective tool for drug repurposing and cell-induced target screening. - Detailed instructions, compound structures, target information, activity descriptions, etc. - Structural diversity, significant druggability and cell penetration. - NMR, HPLC/ LCMS testings to ensure accurate structure and high purity. Uses: Scientific use. Product Category: L4020. Categories: NO PAINS Compounds Libraries.
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