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| Product | Description | |
|---|---|---|
| AAI101 | AAI101 is a novel β-lactamase inhibitor with activity against extended-spectrum β-lactamases (ESBL), as well as, some class A and class D carbapenemases. Uses: Beta-lactamase inhibitors. Synonyms: AAI-101; AAI101. CAS No. 1001404-83-6. Molecular formula: C11H14N4O5S. Mole weight: 314.32. |  |
| Eravacycline dihydrochloride | Eravacycline, a novel fluorocycline previously known as TP-434, in virto has broad-spectrum activity against both Gram-positive and Gram-negative aerobic and anaerobic pathogens including important antimicrobial resistant pathogens such as methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), and extended-spectrum ?-lactamase (ESBL)-producing and carbapenemaseproducing Enterobacteriaceae and multidrug-resistant Acinetobacter baumannii. Synonyms: (4S,4aS,5aR,12aR)-4-(dimethylamino)-7-fluoro-1,10,11,12a-tetrahydroxy-3,12-dioxo-9-[(2-pyrrolidin-1-ylacetyl)amino]-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;dihydrochloride; Eravacycline (dihydrochloride). CAS No. 1334714-66-7. Molecular formula: C27H33Cl2FN4O8. Mole weight: 631.48. | |
| WCK-4234 sodium | WCK-4234 is a potent β-lactamase inhibitor. WCK-4234 inhibited class A, C and D β-lactamases with unprecedented k2/K values against OXA carbapenemases. WCK-4234 inhibited class A, C and D β-lactamases with unprecedented k2/K values against OXA carbapenemases. WCK-4234 formed highly stable acyl-complexes via mass spectrometry. WCK-4234 is a novel β-lactamase inhibitor that demonstate potent cross-class inhibition and clinical studies targeting MDR infections are warranted. Group: Inhibitors. Alternative Names: WCK-4234; WCK 4234; WCK4234. CAS No. 1804915-68-1. Molecular formula: C7H8N3NaO5S. Mole weight: 269.21. Appearance: Solid powder. Purity: >98%. IUPACName: sodium (2S,5R)-2-cyano-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl sulfate. Canonical SMILES: O=S (ON1[C@]2 ([H])CC[C@@H] (C#N)N (C2)C1=O) ([O-])=O. [Na+]. Catalog: ACM1804915681. |  |
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