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| Product | Description | |
|---|---|---|
| Carboplatin | Analog of Cisplatin with reduced nephrotoxicity. Carboplatin is a platinum-based antineoplastic drug that damages DNA by forming intrastrand cross-links with neighboring guanine residues. Tumors acquire resistance to these drugs through the loss of DNA-mismatch repair (MMR) activity and the resultant decrease in the induction of programmed cell death. Group: Biochemicals. Alternative Names: (SP-4-2)-Diamimine[1, 1-cyclobutanedi (carboxylato-kO) (2-)]platinum; cis-Diammine (1, 1-cyclobutane dicarboxylato) platinum (II) ; CBDCA; JM-8; Paraplatin. Grades: Purified. CAS No. 41575-94-4. Pack Sizes: 100mg. US Biological Life Sciences. |  Worldwide |
| Carboplatin | Carboplatin is a DNA synthesis inhibitor by binding to DNA and interfering with the cell's repair mechanism. Uses: Antineoplastic agents. Synonyms: JM-8; JM 8; JM8; CBDCA, NSC 241240; NSC241240; NSC-241240. Grades: >98%. CAS No. 41575-94-4. Molecular formula: C6H12N2O4Pt. Mole weight: 371.25. |  |
| Carboplatin | Carboplatin (NSC 241240) is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death. Carboplatin (NSC 241240) is a derivative of CDDP and a potent anti-cancer agent. Uses: Data on carboplatin production have not been found. carboplatin is used in chemotherapy to treat cancer, and more particularly to treat cancer of ovary, embryonal carcinoma of the testis, microcellular carcinoma of the lung, neuroblastoma, and squamous cell carcinomas of the head and neck.carboplatin, cis-diammine (1, 1-cyclobutanedicarboxylato)platinum (II), is a second-generation platinum drug. Group: Inhibitors. Alternative Names: SR-01000076253; D01363; diammine[cyclobutane-1,1-dicarboxylato(2-)-k2O1,O1]platinum; Carboplatin, British Pharmacopoeia (BP) Reference Standard; MFCD00070464; NSC-241240; CS-1121; NCGC00094961-02; JM-8; SPECTRUM1502106. CAS No. 41575-94-4. Molecular formula: C6H12N2O4Pt;C6H14N2O4Pt. Mole weight: 373.272g/mol. Appearance: Solid. Purity: 0.9996. IUPACName: azane;cyclobutane-1,1-dicarboxylic acid;platinum. Canonical SMILES: C1CC(C1)(C(=O)O)C(=O)O.N.N.[Pt]. ECNumber: 255-446-0. Catalog: ACM41575944. |  |
| Carboplatin | Carboplatin (NSC 241240) is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death. Carboplatin (NSC 241240) is a derivative of CDDP and a potent anti-cancer agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 241240. CAS No. 41575-94-4. Pack Sizes: 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-17393. |  |
| Carboplatin-d4 ((SP-4-2)-Diamimine[1,1-cyclobutane-d4-di(carboxylato-kO)(2-)]platinum,. cis-Diammine (1, 1-cyclobutane-d4-dicarboxylato)platinum (II), CBDCA-d4, JM-8-d4, Paraplatin-d4) | Analog of Cisplatin with reduced nephrotoxicity. Antineoplastic. Group: Biochemicals. Alternative Names: (SP-4-2)-Diamimine[1,1-cyclobutane-d4-di(carboxylato-kO)(2-)]platinum; cis-Diammine (1, 1-cyclobutane-d4-dicarboxylato)platinum (II); CBDCA-d4; JM-8-d4; Paraplatin-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Carboplatin (Diammine(1,1-cyclobutanedicarboxylato)platinum(II)) | 100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C6H12N2O4Pt. CAS No. 41575-94-4. Prepack ID 56513477-100mg. Molecular Weight 371.25. See USA prepack pricing. |  |
| Carboplatin (Diammine(1,1-cyclobutanedicarboxylato)platinum(II)) | 250mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C6H12N2O4Pt. CAS No. 41575-94-4. Prepack ID 56513477-250mg. Molecular Weight 371.25. See USA prepack pricing. | |
| Carboplatin (Diammine(1,1-cyclobutanedicarboxylato)platinum(II)) | 25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C6H12N2O4Pt. CAS No. 41575-94-4. Prepack ID 56513477-25mg. Molecular Weight 371.25. See USA prepack pricing. | |
| Carboplatin EP Impurity B | Carboplatin EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: cyclobutane-1,1-dicarboxylic acid. Molecular Formula: C6H8O4. Mole Weight: 144.13. Catalog: APB04332. |  |
| Carboplatin EP Impurity B | Carboplatin EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 5445-51-2. Molecular Formula: C6H8O4. Mole Weight: 144.13. Catalog: APB5445512. | |
| Carboplatin EP Impurity B (Disilver Salt) | Carboplatin EP Impurity B (Disilver Salt). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Carboplatin EP Impurity B (Disilver Salt). CAS No. 1933502-35-2. Molecular Formula: C6H8O4· 2Ag. Mole Weight: 359.86. Catalog: APB1933502352. | |
| Carboplatin Impurity 1 | an impurity of Carboplatin. Synonyms: Platinate(1-)?, diammine[1,?1-cyclobutanedicarboxy?lato(2-)?-κO]?hydroxy-, (SP-4-3)?-. Grades: > 95%. CAS No. 903630-03-5. Molecular formula: C6H14N2O5Pt. Mole weight: 389.29. | |
| Carboplatin Impurity 1 | Carboplatin Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C6H14N2O5Pt. Mole Weight: 389.27. Catalog: APB04334. | |
| Carboplatin impurity 10 | Carboplatin impurity 10. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C6H15N3O4Pt. Mole Weight: 388.29. Catalog: APB11595. | |
| Carboplatin Impurity 10 | Carboplatin Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 3-oxocyclobutanecarboxylate. CAS No. 695-95-4. Molecular Formula: C6H8O3. Mole Weight: 128.13. Catalog: APB695954. | |
| Carboplatin Impurity 11 | Carboplatin Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Carboplatin Impurity 11. CAS No. 1978330-54-9. Molecular Formula: C5H14ClN3O4Pt. Mole Weight: 410.72. Catalog: APB1978330549. | |
| Carboplatin Impurity 12 | Carboplatin Impurity 12. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C2H9ClN2O3Pt. Mole Weight: 339.64. Catalog: APB04327. | |
| Carboplatin impurity 13 | Carboplatin impurity 13. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C6H14N2O5Pt. Mole Weight: 389.27. Catalog: APB11594. | |
| Carboplatin Impurity 13 (hydrochloride) | Carboplatin Impurity 13 (hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(3-aminopropyl)cyclobutanecarboxylic acid hydrochloride. CAS No. 2098129-29-2. Molecular Formula: C8H15NO2·HCl. Mole Weight: 193.67. Catalog: APB2098129292. | |
| Carboplatin impurity 14 | Carboplatin impurity 14. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C6H14N2O6Pt. Mole Weight: 405.27. Catalog: APB11596. | |
| Carboplatin Impurity 14 | Carboplatin Impurity 14. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: cyclobutanecarboxylic acid. CAS No. 3721-95-7. Molecular Formula: C5H8O2. Mole Weight: 100.12. Catalog: APB3721957. | |
| Carboplatin impurity 15 | Carboplatin impurity 15. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C2H10N2O4Pt. Mole Weight: 321.2. Catalog: APB07579. | |
| Carboplatin Impurity 15 | Carboplatin Impurity 15. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Carboplatin Impurity 15. CAS No. 113287-15-3. Molecular Formula: C6H14N2O6Pt. Mole Weight: 405.27. Catalog: APB113287153. | |
| Carboplatin Impurity 16 | Carboplatin Impurity 16. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C6H15N3O4Pt. Mole Weight: 388.28. Catalog: APB04326. | |
| Carboplatin Impurity 17 | Carboplatin Impurity 17. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C6H12N2O6Pt. Mole Weight: 403.25. Catalog: APB04325. | |
| Carboplatin Impurity 18 | Carboplatin Impurity 18. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C6H16N2O7Pt. Mole Weight: 423.28. Catalog: APB04324. | |
| Carboplatin Impurity 2 | Carboplatin Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C12H26N4O8Pt2. Mole Weight: 744.52. Catalog: APB04333. | |
| Carboplatin impurity 20 | Carboplatin impurity 20. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C12H20N2O8Pt. Mole Weight: 515.38. Catalog: APB07580. | |
| Carboplatin Impurity 4 | Carboplatin Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C6H11NO5Pt. Mole Weight: 372.24. Catalog: APB04331. | |
| Carboplatin Impurity 5 | Carboplatin Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Carboplatin Impurity 5. CAS No. 63700-88-9. Molecular Formula: H8N2O2Pt. Mole Weight: 263.16. Catalog: APB63700889. | |
| Carboplatin Impurity 6 | Carboplatin Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C2H10N2O4Pt. Mole Weight: 321.20. Catalog: APB04330. | |
| Carboplatin Impurity 7 | Carboplatin Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: Cl2H10N2O2Pt. Mole Weight: 336.08. Catalog: APB04329. | |
| Carboplatin Impurity 8 | Carboplatin Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: ClH8N2OPt·Cl. Mole Weight: 318.06. Catalog: APB04328. | |
| Carboplatin impurity 9 | Carboplatin impurity 9. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C6H12N2O6Pt. Mole Weight: 403.25. Catalog: APB11593. | |
| Carboplatin Impurity 9 | Carboplatin Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 3,3-difluorocyclobutanecarboxylate. CAS No. 1234616-13-7. Molecular Formula: C6H8F2O2. Mole Weight: 150.12. Catalog: APB1234616137. | |
| Carboplatin Impurity B (Cyclobutane-1,1-dicarboxylic acid) | an impurity of Carboplatin. Synonyms: 1,1-Cyclobutanedicarboxylic acid. Grades: > 95%. CAS No. 5445-51-2. Molecular formula: C6H8O4. Mole weight: 144.13. | |
| 1, 1-Cyclobutane dicarboxylic Acid | 1, 1-Cyclobutane dicarboxylic Acid is used in the design, studies and structural model of antitumor dicycloplatin a clinical cancer drug. Hydrolysis mechanism of second-generation anticancer drug carboplatin. Group: Biochemicals. Grades: Highly Purified. CAS No. 5445-51-2. Pack Sizes: 5g, 10g. Molecular Formula: C6H8O4. US Biological Life Sciences. | Worldwide |
| Bavituximab | Bavituximab (Anti-Human Phosphatidylserine Recombinant Antibody) is a phosphatidylserine (PS)-targeting monoclonal antibody, suppresses tumor growth by targeting tumor vasculature and reactivating antitumor immunity. Bavituximab plus Paclitaxel (HY-B0015) and Carboplatin (HY-17393), have enhanced inhibition on non-small-cell lung cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human Phosphatidylserine Recombinant Antibody. CAS No. 648904-28-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99279. | |
| Diethyl 1, 1-Cyclobutane dicarboxylate | Intermediate in the production of Carboplatin. Group: Biochemicals. Alternative Names: 1, 1-Cyclobutane dicarboxylic Acid 1,1-Diethyl Ester; NSC 9017. Grades: Highly Purified. CAS No. 3779-29-1. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| Diethyl 1, 1-Cyclobutane dicarboxylate-d4 | Intermediate in the production of labeled Carboplatin. Group: Biochemicals. Alternative Names: 1, 1-Cyclobutane dicarboxylic-d4 Acid 1,1-Diethyl Ester; NSC 9017-d4. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Diethyl 3-Bromopropylmalonate | Byproduct formed during the production of Carboplatin. Group: Biochemicals. Alternative Names: 2- (3-Bromopropyl) propanedioic Acid 1,3-Diethyl Ester; Diethyl 2-(3-Bromopropyl)malonate. Grades: Highly Purified. CAS No. 10149-21-0. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| KRX-0402 | KRX-0402 (O6-benzyl guanine or O6-BG) is a small molecule that was specifically designed to block the DNA repair protein, MGMT. MGMT confers resistance to certain alkylating agents, such as temozolomide and BCNU, that are commonly used to treat brain cancer, melanoma and non-Hodgkin's lymphoma. Recent research has shown that KRX-0402 can also potentiate the activity of other alkylating agents, such as cyclophosphamide, ifosphamide, cisplatinum and carboplatinum. These drugs are some of the most widely used chemotherapy drugs and are commonly used to treat breast cancer, non-small cell lung cancer and ovarian cancer. Accordingly, It is believed that KRX-0402 may have an important role in making cells more susceptible to the damaging effects of alkylating agents, and that KRX-0402 may have utility in the treatment of multiple forms of cancer. KRX-0402 is administered intravenously. To date, approximately 400 patients have received KRX-0402 in multiple clinical studies. Dose limiting toxicity for KRX-0402 in combination with chemotherapy was bone marrow suppression. KRX-0402 alone has no identified dose limiting toxicity. Two company-sponsored, Phase II clinical trials for KRX-0402 are ongoing. Uses: Enzyme inhibitors. Synonyms: KRX 0402; KRX0402; 6-O-Benzylguanine; 6-(Benzyloxy)-7H-purin-2-amine; O(6)-Benzylguanine; 2-Amino-6-(benzyloxy)purine; NSC-637037; O6-BG. CAS No. 1000874-21-4. Molecular formula: C12H11N5O. Mole weight: 241.254. | |
| ML 385 | ML 385 is a novel and specific inhibitor of nuclear factor erythroid 2-related factor 2 (Nrf2; IC50 = 1.9 μM). ML 385 blocks NRF2 transcriptional activity, and enhances the efficacy of carboplatin as well as other chemotherapeutic drugs in lung cancer cells (NSCLC). Synonyms: ML-385; ML 385; ML385; 2-(1,3-benzodioxol-5-yl)-N-[5-methyl-4-[1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl]-1,3-thiazol-2-yl]acetamide. CAS No. 846557-71-9. Molecular formula: C29H25N3O4S. Mole weight: 511.596. | |
| Oxaliplatin EP Impurity C | A metabolite of Oxaliplatin, which is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. Synonyms: (OC-6-33)-[(1R,2R)-cyclohexane-1,2-diamine-kN,kN'][ethanedioato(2-)-κN,κN]dihydroxyplatinum. Grades: > 95%. Molecular formula: C8H14N2O6Pt. Mole weight: 429.3. | |
| Oxaliplatin EP Impurity E | A metabolite of Oxaliplatin, which is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. Synonyms: (SP-4-2)-di-μ-oxidobis[(1R,2R)-cyclohexane-1,2-diamine-1κ2N,2κ2N']diplatinum; Diaquodiaminocyclohexaneplatinum dimer; (SP-4-2)-Di-oxobis[(1R,2R)-1,2-cyclohexanediamine-κN,κN']diplatinum(2+); Platinum(2+), bis(1,2-cyclohexanediamine-N,N')di-μ-hydroxydi-, stereoisomer; 1,2-Cyclohexanediamine, platinum complex, (1R-trans)-. Grades: ≥95%. CAS No. 108033-10-9. Molecular formula: C12H28N4O2Pt2. Mole weight: 650.54. | |
| Oxaliplatin Impurity 1 | A metabolite of Oxaliplatin, which is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. Synonyms: Dihydroxy Oxaliplatin-Pt(IV); (OC-6-33)-[(1R, 2R)-1, 2-Cyclohexanediamine-κN1, κN2][ethanedioato(2-)-κO1, κO2]dihydroxyplatinum. Grades: > 95%. CAS No. 111321-67-6. Molecular formula: C8H16N2O6Pt. Mole weight: 431.31. | |
| Oxaliplatin Impurity B | A metabolite of Oxaliplatin, which is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. Synonyms: (SP-4-2)-diaqua[(1R,2R)-cyclohexane-1,2-diamine-kN,kN']platinum. Grades: > 95%. Molecular formula: C6H18N2O2Pt. Mole weight: 345.3. | |
| Satraplatin | Satraplatin, also known as JM216, is a platinum compound that is currently under investigation as one treatment of patients with advanced prostate cancer who have failed previous chemotherapy. It has not yet received approval from the U.S. Food and Drug Administration. First mentioned in the medical literature in 1993, satraplatin is the first orally active platinum-based chemotherapeutic drug; other available platinum analogues-cisplatin, carboplatin, and oxaliplatin-must be given intravenously. It is made available in the United States jointly by Spectrum Pharmaceuticals and GPC Biotech under the name SPERA (Satraplatin Expanded Rapid Access). The drug has also been used in the treatment of lung and ovarian cancers. The proposed mode of action is that the compound binds to the DNA of cancer cells rendering them incapable of dividing. Synonyms: BMS-182751; BMS 182751; BMS182751; JM 216; JM216; JM-216. CAS No. 129580-63-8. Molecular formula: C10H24Cl2N2O4Pt. Mole weight: 500.28. | |
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