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gibberellin A4 carboxyl methyltransferase The enzyme also methylates gibberellins A34 (80%), A9 (60%), and A3 (45%) with significant activity. Group: Enzymes. Synonyms: GAMT2; gibberellin A4 O-methyltransferase. Enzyme Commission Number: EC 2.1.1.276. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1882; gibberellin A4 carboxyl methyltransferase; EC 2.1.1.276; GAMT2; gibberellin A4 O-methyltransferase. Cat No: EXWM-1882. Creative Enzymes
phenazine-1-carboxylate N-methyltransferase The enzyme, characterized from the bacterium Pseudomonas aeruginosa, is involved in the biosynthesis of pyocyanin, a toxin produced and secreted by the organism. The enzyme is active in vitro only in the presence of EC 1.14.13.218, 5-methylphenazine-1-carboxylate 1-monooxygenase. Group: Enzymes. Synonyms: phzM (gene name). Enzyme Commission Number: EC 2.1.1.327. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1935; phenazine-1-carboxylate N-methyltransferase; EC 2.1.1.327; phzM (gene name). Cat No: EXWM-1935. Creative Enzymes
[ribulose-bisphosphate carboxylase]-lysine N-methyltransferase The enzyme catalyses three successive methylations of Lys-14 in the large subunits of hexadecameric higher plant ribulose-bisphosphate-carboxylase (EC 4.1.1.39). Only the three methylated form is observed. The enzyme from pea (Pisum sativum) also three-methylates a specific lysine in the chloroplastic isoforms of fructose-bisphosphate aldolase (EC 4.1.2.13). Group: Enzymes. Synonyms: rubisco methyltransferase; ribulose-bisphosphate-carboxylase/oxygenase N-methyltransferase; ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit εN-methyltransferase; S-adenosyl-L-methionine:[3-phospho-D-glycerate-carboxy-lyase (dimerizing)]-lysine 6-N-methyltransferase; RuBisCO methyltransf. Enzyme Commission Number: EC 2.1.1.127. CAS No. 139171-98-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1724; [ribulose-bisphosphate carboxylase]-lysine N-methyltransferase; EC 2.1.1.127; 139171-98-5; rubisco methyltransferase; ribulose-bisphosphate-carboxylase/oxygenase N-methyltransferase; ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit εN-methyltransferase; S-adenosyl-L-methionine:[3-phospho-D-glycerate-carboxy-lyase (dimerizing)]-lysine 6-N-methyltransferase; RuBisCO methyltransferase; RuBisCO LSMT. Cat No: EXWM-1724. Creative Enzymes
2-(Benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylic Acid 2-(Benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylic Acid is a small molecule that has been reported as a novel histone methyltransferase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1374601-41-8. Pack Sizes: 1mg, 5mg. Molecular Formula: C24H21N3O3, Molecular Weight: 399.44. US Biological Life Sciences. USBiological 9
Worldwide
2-polyprenyl-6-hydroxyphenol methylase UbiG catalyses both methylation steps in ubiquinone biosynthesis in Escherichia coli. The second methylation is classified as EC 2.1.1.64 (3-demethylubiquinol 3-O-methyltransferase). In eukaryotes Coq3 catalyses the two methylation steps in ubiquinone biosynthesis. However, while the second methylation is common to both enzymes, the first methylation by Coq3 occurs at a different position within the pathway, and thus involves a different substrate and is classified as EC 2.1.1.114 (polyprenyldihydroxybenzoate methyltransferase). The substrate of the eukaryotic enzyme (3,4-dihydroxy-5-all-trans-polyprenylbenzoate) differs by an additional carboxylate moiety. Group: Enzymes. Synonyms: ubiG (gene name, ambiguous); ubiG methyltransferase (ambiguous); 2-octaprenyl-6-hydroxyphenol methylase. Enzyme Commission Number: EC 2.1.1.222. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1825; 2-polyprenyl-6-hydroxyphenol methylase; EC 2.1.1.222; ubiG (gene name, ambiguous); ubiG methyltransferase (ambiguous); 2-octaprenyl-6-hydroxyphenol methylase. Cat No: EXWM-1825. Creative Enzymes
benzoate O-methyltransferase While the enzyme from the plant Zea mays is specific for benzoate, the enzymes from Arabidopsis species and Clarkia breweri also catalyse the reaction of EC 2.1.1.274, salicylate 1-O-methyltransferase. In snapdragon (Antirrhinum majus) two isoforms are found, one specific for benzoate and one that is also active towards salicylate. The volatile product is an important scent compound in some flowering species. Group: Enzymes. Synonyms: BAMT; S-adenosyl-L-methionine:benzoic acid carboxyl methyltransferase. Enzyme Commission Number: EC 2.1.1.273. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1879; benzoate O-methyltransferase; EC 2.1.1.273; BAMT; S-adenosyl-L-methionine:benzoic acid carboxyl methyltransferase. Cat No: EXWM-1879. Creative Enzymes
CAY10677 Isoprenylcysteine Carboxyl Methyltransferase (ICMT) is a protein coding gene. Diseases associated with ICMT include Hallermann-Streiff syndrome and Legionnaire disease. CAY10677 is an analog of the ICMT inhibitor cysmethynil that was developed for improved solubility and cell permeability. It inhibits ICMT with an IC50 value of 0.86 μM and demonstrates nearly 10-fold more potent antiproliferative activity than cysmethynil on human breast cancer MDA-MB-231 cells and human prostate cancer PC3 cells. Synonyms: Icmt Inhibitor 15; CAY 10677; CAY-10677. Grades: ≥98%. CAS No. 1443253-20-0. Molecular formula: C25H37N5. Mole weight: 407.6. BOC Sciences 9
Cysmethynil Cysmethynil is a potent inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT) with antitumor activity in cancer cells. Cysmethynil treatment results in inhibition of cell growth in an Icmt-dependent fashion, demonstrating mechanism-based activity of the compound. Treatment of cancer cells with cysmethynil results in mislocalization of Ras and impaired epidermal growth factor signaling. In a human colon cancer cell line, cysmethynil treatment blocks anchorage-independent growth, and this effect is reversed by overexpression of Icmt. Synonyms: 2-(1-octyl-5-m-tolyl-1H-indol-3-yl)acetamide; 1H-Indole-3-acetamide, 5-(3-methylphenyl)-1-octyl-. CAS No. 851636-83-4. Molecular formula: C25H32N2O. Mole weight: 376.54. BOC Sciences 11
DC-S239 DC-S239 is a potent and selective histone methyltransferase SET7 inhibitor. Group: Inhibitors. Alternative Names: DC-S239; DC S239; DCS239. CAS No. 303141-21-1. Molecular formula: C15H15N3O5S. Mole weight: 349.36. Appearance: Solid powder. Purity: >98%. IUPACName: Ethyl 2-Amino-4-methyl-5-((3-nitrophenyl)carbamoyl)-thiophene-3-carboxylate. Canonical SMILES: O=C (C1=C (N)SC (C (NC2=CC=CC ([N+] ([O-])=O)=C2)=O)=C1C)OCC. Catalog: ACM303141211. Alfa Chemistry.
(E,E)-Farnesyl Thioacetate (E,E)-Farnesyl Thioacetate, an acetate derivative of (E,E)-Farnesyl Thiol, has inhibitory activity against human isoprenylcysteine carboxyl methyltransferase (Icmt) protein. Synonyms: Ethanethioic Acid S-[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl] Ester; Ethanethioic Acid S-[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl] Ester; S-[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl] ethanethioate. Grades: ≥95%. CAS No. 340701-35-1. Molecular formula: C17H28OS. Mole weight: 280.47. BOC Sciences 8
[fructose-bisphosphate aldolase]-lysine N-methyltransferase The enzyme methylates a conserved lysine in the C-terminal part of higher plant fructose-bisphosphate aldolase (EC 4.1.2.13). The enzyme from pea (Pisum sativum) also methylates Lys-14 in the large subunits of hexadecameric higher plant ribulose-bisphosphate-carboxylase (EC 4.1.1.39), but that from Arabidopsis thaliana does not. Group: Enzymes. Synonyms: rubisco methyltransferase; ribulose-bisphosphate-carboxylase/oxygenase N-methyltransferase; ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit εN-methyltransferase; S-adenosyl-L-methionine:[3-phospho-D-glycerate-carboxy-lyase (dimerizing)]-lysine 6-N-methyltransferase. Enzyme Commission Number: EC 2.1.1.259. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1863; [fructose-bisphosphate aldolase]-lysine N-methyltransferase; EC 2.1.1.259; rubisco methyltransferase; ribulose-bisphosphate-carboxylase/oxygenase N-methyltransferase; ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit εN-methyltransferase; S-adenosyl-L-methionine:[3-phospho-D-glycerate-carboxy-lyase (dimerizing)]-lysine 6-N-methyltransferase. Cat No: EXWM-1863. Creative Enzymes
ICMT Inhibitor (Cysmethynil) An inhibitor of protein prenylation. Cysmethynil is a potent inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT) with antitumor activity in cancer cells. Cysmethynil treatment results in inhibition of cell growth in an Icmt-dependent fashion, demonstrating mechanism-based activity of the compound. Treatment of cancer cells with cysmethynil results in mislocalization of Ras and impaired epidermal growth factor signaling. In a human colon cancer cell line, cysmethynil treatment blocks anchorage-independent growth, and this effect is reversed by overexpression of Icmt.A cell-permeable indole acetamide that acts as a substrate-competitive and AdoMet-noncompetitive Icmt...25uM) induces G1 cell cycle-arrest and autophagy-mediated, but not apoptotic, cell death in prostate cancer PC3 cells with concomitant PI 3-K/Akt and mTOR signaling blockage, consistent with inhibition of Icmt-mediated activation of Ras and Rheb GTPases. Murine PC3 xenograft studies reveal limited in vivo efficacy. Group: Biochemicals. Alternative Names: Cysmethynil; 2-(5-(3-Methylphenyl)-1-octyl-1H-indol-3-yl)acetamide, 2-(1-Octyl-5-m-tolyl-1H-indol-3-yl) acetamide; Isoprenylcysteine Carboxyl Methyltransferase Inhibitor). Grades: Highly Purified. CAS No. 851636-83-4. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C25H32N2O, Molecular Weight: 376.5. US Biological Life Sciences. USBiological 4
Worldwide
ICMT Inhibitor II, FTPAT ((E)-methyl-3-((5-(4-(2-((1,1’-biphenyl]-4-yl)ethyl)-1H-1,2,3-triazol-1-yl)-3-methylpent-2-en-1-yl)thio)propanoate) A cell-permeable triazolo-farnesylthiopropanoate compound that acts as a potent, reversible, and isoprenyl mimetic competitive inhibitor of isoprenylcysteine carboxyl methyltransferase activity (ICMT; IC50=800nM; Ki=400nM). Shown to prevent K-Ras membrane localization in GFP-K-Ras transfected Jurkat T-cells. Exhibits selective toxicity towards wt-Icmt+/+ mouse embryonic fibroblasts (MEFs) over Icmt-/- MEFs (IC50=33 and >100uM). Also shown to arrest the proliferation of PaTu-8902, a highly metastatic pancreatic cancer cells (IC50=8uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
Worldwide
indole-3-acetate O-methyltransferase Binds Mg2+. The enzyme is found in plants and is important for regulation of the plant hormone (indol-3-yl)acetate. The product, methyl (indol-3-yl)acetate is inactive as hormone. Group: Enzymes. Synonyms: IAA carboxylmethyltransferase; IAMT. Enzyme Commission Number: EC 2.1.1.278. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1884; indole-3-acetate O-methyltransferase; EC 2.1.1.278; IAA carboxylmethyltransferase; IAMT. Cat No: EXWM-1884. Creative Enzymes
jasmonate O-methyltransferase 9,10-Dihydrojasmonic acid is a poor substrate for the enzyme. The enzyme does not convert 12-oxo-phytodienoic acid (a precursor of jasmonic acid), salicylic acid, benzoic acid, linolenic acid or cinnamic acid into their corresponding methyl esters. Enzyme activity is inhibited by the presence of divalent cations, e.g., Ca2+, Cu2+, Mg2+ and Zn2+. Group: Enzymes. Synonyms: jasmonic acid carboxyl methyltransferase. Enzyme Commission Number: EC 2.1.1.141. CAS No. 346420-58-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1737; jasmonate O-methyltransferase; EC 2.1.1.141; 346420-58-4; jasmonic acid carboxyl methyltransferase. Cat No: EXWM-1737. Creative Enzymes
malonyl-[acyl-carrier protein] O-methyltransferase Involved in an early step of biotin biosynthesis in Gram-negative bacteria. This enzyme catalyses the transfer of a methyl group to the ω-carboxyl group of malonyl-[acyl-carrier protein] forming a methyl ester. The methyl ester is recognized by the fatty acid synthetic enzymes, which process it via the fatty acid elongation cycle to give pimelyl-[acyl-carrier-protein] methyl ester. While the enzyme can also accept malonyl-CoA, it has a much higher activity with malonyl-[acyl-carrier protein]. Group: Enzymes. Synonyms: BioC. Enzyme Commission Number: EC 2.1.1.197. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1796; malonyl-[acyl-carrier protein] O-methyltransferase; EC 2.1.1.197; BioC. Cat No: EXWM-1796. Creative Enzymes
Native Protein Methylase II Methylation of proteins is one of the key reactions in the post-translational modification of protein amino acid residues in the cell. It has been established that the basic and acidic amino acid residues of certain proteins are methylated in vivo. Protein methylase II methylates the free carboxyl groups of dicarboxylic acid residues in a protein molecule. Existence of this enzyme, in mammalian tissues, was first reported by Liss and Edelstein. Protein methylase II from ox brain has been purified by Iqbal and Steenson. Group: Enzymes. Synonyms: S-adenosylmethionine:protein Carboxyl O-methyltransferase; EC 2.1.1.24; Protein Methylase II. Enzyme Commission Number: EC 2.1.1.24. Protein Methylase II. S-adenosylmethionine:protein Carboxyl O-methyltransferase; EC 2.1.1.24; Protein Methylase II. Cat No: NATE-0895. Creative Enzymes
protein-glutamate methylesterase Hydrolyses the products of EC 2.1.1.77 (protein-L-isoaspartate(D-aspartate) O-methyltransferase), EC 2.1.1.78 (isoorientin 3'-O-methyltransferase), EC 2.1.1.80 (protein-glutamate O-methyltransferase) and EC 2.1.1.100 (protein-S-isoprenylcysteine O-methyltransferase). Group: Enzymes. Synonyms: chemotaxis-specific methylesterase; methyl-accepting chemotaxis protein methyl-esterase; CheB methylesterase; methylesterase CheB; protein methyl-esterase; protein carboxyl methylesterase; PME; protein methylesterase; protein-L-glutamate-5-O-methyl-ester acylhydrolase. Enzyme Commission Number: EC 3.1.1.61. CAS No. 69552-31-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3490; protein-glutamate methylesterase; EC 3.1.1.61; 69552-31-4; chemotaxis-specific methylesterase; methyl-accepting chemotaxis protein methyl-esterase; CheB methylesterase; methylesterase CheB; protein methyl-esterase; protein carboxyl methylesterase; PME; protein methylesterase; protein-L-glutamate-5-O-methyl-ester acylhydrolase. Cat No: EXWM-3490. Creative Enzymes
protein-glutamate O-methyltransferase Forms ester groups with L-glutamate residues in a number of membrane proteins. Group: Enzymes. Synonyms: methyl-accepting chemotaxis protein O-methyltransferase; S-adenosylmethionine-glutamyl methyltransferase; methyl-accepting chemotaxis protein methyltransferase II; S-adenosylmethionine:protein-carboxyl O-methyltransferase; protein methylase II; MCP methyltransferase I; MCP methyltransferase II; protein O-methyltransferase; protein(aspartate)methyltransferase; protein(carboxyl)methylt. Enzyme Commission Number: EC 2.1.1.80. CAS No. 9055-9-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1982; protein-glutamate O-methyltransferase; EC 2.1.1.80; 9055-09-8; methyl-accepting chemotaxis protein O-methyltransferase; S-adenosylmethionine-glutamyl methyltransferase; methyl-accepting chemotaxis protein methyltransferase II; S-adenosylmethionine:protein-carboxyl O-methyltransferase; protein methylase II; MCP methyltransferase I; MCP methyltransferase II; protein O-methyltransferase; protein(aspartate)methyltransferase; protein(carboxyl)methyltransferase; protein carboxyl-methylase; protein carboxyl-O-methyltransferase; protein carboxylmethyltransferase II; protein carboxymethylase; protein carboxymethyltransferase; protein methyltransferase II. Cat No: EXWM-1982. Creative Enzymes
protein-L-isoaspartate(D-aspartate) O-methyltransferase D-Aspartate (but not L-aspartate) residues in proteins can also act as acceptors. Previously also listed as EC 2.1.1.24. Group: Enzymes. Synonyms: protein-L-isoaspartate O-methyltransferase; protein-β-aspartate O-methyltransferase; D-aspartyl/L-isoaspartyl methyltransferase; L-isoaspartyl/D-aspartyl protein carboxyl methyltransferase; protein (D-aspartate) methyltransferase; protein D-aspartate methyltransferase; protein L-isoaspartate methyltransferase; protein L-isoaspartyl methyltransferase; protein O-methyltransferase (L-isoaspartate); L-aspartyl/L-isoaspartyl protein me. Enzyme Commission Number: EC 2.1.1.77. CAS No. 105638-50-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1978; protein-L-isoaspartate(D-aspartate) O-methyltransferase; EC 2.1.1.77; 105638-50-4; protein-L-isoaspartate O-methyltransferase; protein-β-aspartate O-methyltransferase; D-aspartyl/L-isoaspartyl methyltransferase; L-isoaspartyl/D-aspartyl protein carboxyl methyltransferase; protein (D-aspartate) methyltransferase; protein D-aspartate methyltransferase; protein L-isoaspartate methyltransferase; protein L-isoaspartyl methyltransferase; protein O-methyltransferase (L-isoaspartate); L-aspartyl/L-isoaspartyl protein methyltransferase. Cat No: EXWM-1978. Creative Enzymes
protein-S-isoprenylcysteine O-methyltransferase C-terminal S-geranylgeranylcysteine and S-geranylcysteine residues are also methylated, but more slowly. Group: Enzymes. Synonyms: farnesyl cysteine C-terminal methyltransferase; farnesyl-protein carboxymethyltransferase; protein C-terminal farnesylcysteine O-methyltransferase; farnesylated protein C-terminal O-methyltransferase; isoprenylated protein methyltransferase; prenylated protein methyltransferase; protein S-farnesylcysteine C-terminal methyltransferase; S-farnesylcysteine methyltransferase; prenylcysteine carboxylmethyltra. Enzyme Commission Number: EC 2.1.1.100. CAS No. 130731-20-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1698; protein-S-isoprenylcysteine O-methyltransferase; EC 2.1.1.100; 130731-20-3; farnesyl cysteine C-terminal methyltransferase; farnesyl-protein carboxymethyltransferase; protein C-terminal farnesylcysteine O-methyltransferase; farnesylated protein C-terminal O-methyltransferase; isoprenylated protein methyltransferase; prenylated protein methyltransferase; protein S-farnesylcysteine C-terminal methyltransferase; S-farnesylcysteine methyltransferase; prenylcysteine carboxylmethyltransferase [misleading]; prenylcysteine carboxymethyltransferase [misleading]; prenylcysteine methyltransferase. Cat No: EXWM-1698. Creative Enzymes
S-Adenosyl-L-methionine p-toluenesulfonate S-(5?-Adenosyl)-L-methionine (SAM) is anti-apoptotic in normal hepatocytes and normal colon epithelial cells but pro-apoptotic in liver human hepatocellular carcinoma (HCC), HepG2 cells and colon cancer cells. Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury. Group: Biochemicals. Alternative Names: (3S) -5'-[ (3-Amino-3-carboxylatopropyl) methylsulphonio]-5'-deoxyadenosine) ; SAMe p-toluenesulfonate; S-Adenosylmethionine Tosylate; Adomet; Ademetionine. Grades: Highly Purified. CAS No. 17176-17-9. Pack Sizes: 10g, 25g, 50g, 100g. US Biological Life Sciences. USBiological 8
Worldwide
salicylate 1-O-methyltransferase The enzyme, which is found in flowering plants, also has the activity of EC 2.1.1.273, benzoate O-methyltransferase. Group: Enzymes. Synonyms: SAMT; S-adenosyl-L-methionine:salicylic acid carboxyl methyltransferase; salicylate carboxymethyltransferase. Enzyme Commission Number: EC 2.1.1.274. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1880; salicylate 1-O-methyltransferase; EC 2.1.1.274; SAMT; S-adenosyl-L-methionine:salicylic acid carboxyl methyltransferase; salicylate carboxymethyltransferase. Cat No: EXWM-1880. Creative Enzymes
HMTase Inhibitor VI, BRD4770 (Methyl-2-benzamido-1-(3-phenylpropyl)-1H-benzo[d]imidazole-5-carboxylate) A cell-permeable analog of the amino-benzimidazolo BIX-01338 and the methylester prodrug of BRD9539 that acts as an SAM-competitive inhibitor against PRC2 and G9a (IC50<6.3uM) histone methyltransferase activities, displaying little effect toward 10 other HMTases, 9 HDACs, and 100 cellular kinases. Selectively reduces H3K9me2 and H3K9me3 (EC50=5uM) histone methylation levels in pancreatic cancer cells (PANC-1) with much less or little effect toward H3K36me3, H3K4me3, H3K27me3, or H3K6me3 levels. Inhibits both anchorage-dependent and -independent PANC-1 proliferation via ATM activation and G2/M cell-cycle arrest, but not apoptosis induction (no caspase3/7 activation; 10uM, 72h). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
Worldwide

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