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| Product | Description | |
|---|---|---|
| cathepsin B | An intracellular (lysosomal) enzyme in peptidase family C1 (papain family). Group: Enzymes. Synonyms: cathepsin B1 (obsolete); cathepsin II. Enzyme Commission Number: EC 3.4.22.1. CAS No. 9047-22-7. Cathepsin B. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4192; cathepsin B; EC 3.4.22.1; 9047-22-7; cathepsin B1 (obsolete); cathepsin II. Cat No: EXWM-4192. |  |
| Cathepsin B Active human | recombinant, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. |  |
| Cathepsin B, Bovine spleen | Cathepsin B, Bovine spleen is a cysteine protease and is involved in multiple kinds of programmed cell death (including apoptosis, pyroptosis, ferroptosis, necroptosis, and autophagic cell death) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9047-22-7. Pack Sizes: 100 μg. Product ID: HY-P2780. |  |
| Cathepsin B from human liver | buffered aqueous solution, ?1,500 units/mg protein (E1%/280). Group: Fluorescence/luminescence spectroscopy. | |
| Cathepsin B from Human, recombinant | Cathepsin B is a lysosomal cysteine protease. It is implicated in playing a role in protein degradation, arthritis, apoptosis, and cancer. Group: Enzymes. Synonyms: CTSB; 9047-22-7; APPS; CPSB; cathepsin B1 (obsolete); cathepsin II. Enzyme Commission Number: EC 3.4.22.1. CAS No. 9047-22-7. Purity: > 90% by SDS-PAGE. Cathepsin B. Mole weight: 27.8 kDa (80-333 aa). Activity: >7500 mU/mg. Storage: Stable for at least 1 year as supplied. Dilute in de-ionized water to 0.1 mg/ml and store at -80°C. Avoid repeated freezing and thawing cycles. Form: Liquid. Source: E. coli. Species: Human. CTSB; cathepsin B; 9047-22-7; APPS; CPSB; cathepsin B1 (obsolete); cathepsin II; EC 3.4.22.1. Cat No: NATE-1706. | |
| Cathepsin B, Human Liver | Cathepsin B, Human Liver, CAS 9047-22-7, is a purified native cathepsin B from human liver, purified by affinity chromatography. Upregulated in many types of tumors. Group: Fluorescence/luminescence spectroscopy. | |
| Cathepsin B Substrate III, Fluorogenic | Sensitive fluorogenic substrate for the quantitative determination of cathepsin B activity. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Cathepsin B antibody, Mouse monoclonal | clone CB59-4B11, purified from hybridoma cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Cathepsin K antibody produced in goat | affinity isolated antibody, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Cathepsin D/E Substrate, Fluorogenic | An internally quenched fluorogenic 11-mer peptide that acts as a sensitive and selective substrate for cathepsins D and E, but not cathepsins B, H, or L. Group: Fluorescence/luminescence spectroscopy. | |
| Cathepsin D from Human, recombinant | Cathepsin D is a lysosomal aspartyl protease composed of a protein dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is an estrogen-regulated protein associated with tissue breakdown. Levels of cathepsin D have been positively correlated with recurring breast cancers of both node negative and node positive types. Additionally cathepsin D has been associated with amyloid formation in Alzheimer's plaques. Cathepsin D is produced initially as a pre-pro-enzyme which gets transported to lysosomes via endosomes in most cell types. In endosomes, it gets proteolyzed by unidentified proteases by removal of the pro-peptide to generate...e cathepsins B and L generates mature, active double-chain Cathepsin D. Group: Enzymes. Synonyms: CTSD; 9025-26-7; EC 3.4.23.5; CLN10; CPSD; HEL-S-130P; Procathepsin D. Enzyme Commission Number: EC 3.4.23.5. CAS No. 9025-26-7. Purity: > 80% by SDS-PAGE. CTSD. Mole weight: 45.1 kDa. Activity: >100 pmol/min/mg. Storage: Store at -20°C. Stable for at least 6 months as supplied. Reconstitute to 1 mg/ml in sterile water, store at -80°C in aliquots and use within 6 months after reconstitution. Avoid repeated freeze-thaw cycles. Form: Freeze-Dried. Source: E. coli. Species: Human. CTSD; cathepsin D; 9025-26-7; EC 3.4.23.5; CLN10; CPSD; HEL-S-130P; Procathepsin D. Cat No: NATE-1707. | |
| Cathepsin F from Human, Recombinant | Cathepsin F, also known as CTSF, belongs to the cathepsin family. Cathepsins are papain familycysteine proteinases that represent a major component of the lysosomal proteolytic system. The CTSF gene isubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W. CTSF isthought to play a role in normal protein catabolism, and because it is highly expressed in some cancer cell lines, itmay be involved in degradative processes occurring during tumor progression. Recombinant human CTSF protein,fused to His-tag at N-terminus, was expressed in E.coli. Group: Enzymes. Enzyme Commission Number: EC 3.4.22.41. Mole weight: This protein is fused with a 6× His tag at N-terminus and has a calculated MW of 26 kDa. Form: Liquid. Source: E. coli. Species: Human. Cat No: NATE-1666. | |
| Cathepsin G Inhibitor I | Cathepsin G inhibitor I is a potent and selective inhibitor of cathepsin G with IC50 of 53 nM. It weakly inhibits chymotrypsin and poorly inhibits thrombin, factor Xa, factor IXa, plasmin, trypsin, tryptase, proteinase 3, and human leukocyte elastase. Synonyms: Cathepsin G Inhibitor I; 429676-93-7; Cathepsin G Inhibitor; CHEMBL164694; [2-[3-[(1-benzoylpiperidin-4-yl)-methylcarbamoyl]naphthalen-2-yl]-1-naphthalen-1-yl-2-oxoethyl]phosphonic acid; SCHEMBL1613660; DTXSID80431393; BDBM50139754; HY-103351; CS-0027703; A918760; (2-{3-[(1-Benzoyl-piperidin-4-yl)-methyl-carbamoyl]-naphthalen-2-yl}-1-naphthalen-1-yl-2-oxo-ethyl)-phosphonic acid; [2-[3-[(1-benzoylpiperidin-4-yl)-methylcarbamoyl]naphthalen-2-yl]-1-naphthalen-1-yl-2 oxoethyl]phosphonic acid. Grades: ≥95%. CAS No. 429676-93-7. Molecular formula: C36H33N2O6P. Mole weight: 620.6. |  |
| Cathepsin Inhibitor 1 | Cathepsin Inhibitor 1 is a pan-inhibitor of Cathepsin (L, L2, S, K, B). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Cathepsin Inhibitor 1; Cathepsin-Inhibitor-1; CTS-IN-1; CTS IN 1. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 225120-65-0. Molecular formula: C20H24ClN5O2. Mole weight: 401.89. Purity: >98%. IUPACName: (S)-3-(tert-butyl)-N-(3-(3-chlorophenyl)-1-((cyanomethyl)amino)-1-oxopropan-2-yl)-1-methyl-1H-pyrazole-5-carboxamide. Canonical SMILES: ClC1=CC=CC(C[C@@H](C(NCC#N)=O)NC(C2=CC(C(C)(C)C)=NN2C)=O)=C1. Product ID: ACM225120650. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Cathepsin Inhibitor 1 | Osteoarthritis is currently recognized as a chronic degenerative disease, which is caused by the loss of articular cartilage and damage to underlying bone, resulting in joint instability and pain. Cathepsin Inhibitor 1 is an inhibitor of Cathepsin. The IC50s for Cathepsin L, L2, S, K, B are 7.9, 6.7, 6.0, 5.5 and 5.2 nM, respectively. Synonyms: Cathepsin-Inhibitor-1; CTS-IN-1; CTS IN 1. Grades: ≥98%. CAS No. 225120-65-0. Molecular formula: C20H24ClN5O2. Mole weight: 401.89. | |
| Cathepsin K from Human, recombinant | Cathepsin K, a member of the papain cysteine proteinase family is the predominant proteinase responsible for the resorption of the bone matrix. Cathepsin cleaves proteins such as collagen type I, collagen type II and osteonectin, thereby playing a role in bone remodeling and resorption in osteoporosis, osteolytic bone metastasis and rheumatoid arthritis. Group: Enzymes. Synonyms: CTSK; CTSO; CTSO3; Cathepsin O; Cathepsin O2; Cathepsin X; EC 3.4.22.38. Enzyme Commission Number: EC 3.4.22.38. CAS No. 94716-09-3. Purity: > 95% by SDS-PAGE. Activity: >900 mU/mg protein. Storage: at -80°C. Avoid freeze/thaw. Form: Liquid. Source: E. coli. Species: Human. CTSK; CTSO; CTSO3; Cathepsin O; Cathepsin O2; Cathepsin X; EC 3.4.22.38. Cat No: NATE-1705. | |
| Cathepsin K from Mouse, recombinant | Cathepsin K, a member of the papain cysteine proteinase family is the predominant proteinase responsible for the resorption of the bone matrix. Cathepsin cleaves proteins such as collagen type I, collagen type II and osteonectin, thereby playing a role in bone remodeling and resorption in osteoporosis, osteolytic bone metastasis and rheumatoid arthritis. Group: Enzymes. Synonyms: CTSK; CTSO; CTSO3; Cathepsin O; Cathepsin O2; Cathepsin X; EC 3.4.22.38. Enzyme Commission Number: EC 3.4.22.38. CAS No. 94716-09-3. Purity: > 90% by SDS-PAGE. Mole weight: 23.4 kDa (115-329 aa). Activity: >1000 mU/mg. Storage: Stable for 6 months at -80°C. Use as provided or dilute to 0.1 mg/ml with 50% glycerol. Aliquot and store at -80°C. Avoid repeated freezing and thawing cycles, as this may lead to the loss in its activity over time. Form: Liquid. Source: E. coli. Species: Mouse. CTSK; CTSO; CTSO3; Cathepsin O; Cathepsin O2; Cathepsin X; EC 3.4.22.38. Cat No: NATE-1704. | |
| Cathepsin K from Rat, recombinant | Cathepsin K, a member of the papain cysteine proteinase family is the predominant proteinase responsible for the resorption of the bone matrix. Cathepsin cleaves proteins such as collagen type I, collagen type II and osteonectin, thereby playing a role in bone remodeling and resorption in osteoporosis, osteolytic bone metastasis and rheumatoid arthritis. Group: Enzymes. Synonyms: CTSK; CTSO; CTSO3; Cathepsin O; Cathepsin O2; Cathepsin X; EC 3.4.22.38. Enzyme Commission Number: EC 3.4.22.38. CAS No. 94716-09-3. Purity: > 90% by SDS-PAGE. Mole weight: 23.5 kDa (115-329 aa). Activity: >500 mU/mg. Storage: Stable for 6 months at -80°C. Use as provided or dilute to 0.1 mg/ml with 50% glycerol. Aliquot and store at -80°C. Avoid repeated freezing and thawing cycles, as this may lead to the loss in its activity over time. Form: Liquid. Source: E. coli. Species: Rat. CTSK; CTSO; CTSO3; Cathepsin O; Cathepsin O2; Cathepsin X; EC 3.4.22.38. Cat No: NATE-1703. | |
| Cathepsin K, His Tag, Human, Recombinant, E. coli | Cathepsin K, Human, Recombinant, E. coli, CAS 94716-09-3, of the papain superfamily of cysteine proteinases plays a role in osteoclast-mediated bone resorption and collagen degradation. Group: Fluorescence/luminescence spectroscopy. | |
| Cathepsin K Substrate II, Fluorogenic | An internally quenched, highly cathepsin K-selective, fluorogenic peptide substrate that is efficiently cleaved by CatK (kcat/Km = 0.426 μM?¹ S?¹), but not by Cathepsins B/L/S/F/H/V. Group: Fluorescence/luminescence spectroscopy. | |
| Cathepsin L from Human, Recombinant | Cathepsin L (EC 3.4.22.15, Aldrichina grahami cysteine proteinase) is an important lysosomal endopeptidase enzyme which is involved in the initiation of protein degradation. It is a member of the Peptidase C1 family, which play an important role in diverse processes including normal lysosome mediated protein turnover, antigen and proprotein processing, and apoptosis. Cathepsin L has been reported in many organisms including fish, birds and mammals. Group: Enzymes. Synonyms: Cathepsin L1; Major excreted protein; Cathepsin U; Cathepsin V. Enzyme Commission Number: EC 3.4.22.15. Purity: > 90% by SDS-PAGE. CTSL. Mole weight: 24.2 kDa (114-333 aa). Activity: > 10000 mU/mg. Stability: Stable for at least 6 months as supplied. Use as provided or dilute with 50% glycerol to 0.1 mg/ml. Aliquot immediately and store at -80°C. Avoid freeze/thaw cycles. Storage: Store at -80°C. Form: Liquid. Source: E. coli. Species: Human. cathepsin L; CTSL; EC 3.4.22.15; Aldrichina grahami cysteine proteinase; 60616-82-2; Cathepsin L1; Major excreted protein; Cathepsin U; Cathepsin V. Cat No: NATE-1665. | |
| Cathepsin L Inhibitor | Cathepsin L inhibitor is a potent inhibitor of cathepsin L with IC50 of 0.85 nM. It is trypanocidal with an ED50 value of 45 nM against T. brucei that is well below the ED50 value of 21,500 nM for human HL-60 cells. In vivo, cathepsin L inhibitor (2.5-10 mg/kg) inhibits bone loss in a mouse model of osteoporosis in a dose-dependent manner. Cathepsin L inhibitor can also completely suppress osteoclastic pit formation on femur slices isolated from bovine cortical bone. Synonyms: Z-FY-CHO; Z-Phe-Tyr-aldehyde; SB 412515; N-(benzyloxycarbonyl)-phenylalanyl-l-tyrosinal. Grades: ≥95%. CAS No. 167498-29-5. Molecular formula: C26H26N2O5. Mole weight: 446.49. | |
| Cathepsin S from Human, recombinant | Cathepsin S (CTSS) is a lysosomal cysteine protease of the papain family and may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. CTSS is synthesized as inactive precursor of 331 amino acids consisting of a 15-aa signal peptide, a propeptide of 99 aa, and a mature polypeptide of 217 aa. It is activated in the lysosomes by a proteolytic cleavage of the propeptide. The deduced amino acid sequence contains only one potential N-glycosylation site located in the propeptide. Compared with the abundant cathepsins B, L and H, cathepsin S shows a restricted tissue distribution, with highest levels in spleen, heart, and lung...l compartment, and is implicated in the pathogenesis of Alzheimers disease and Down Syndrome. Group: Enzymes. Synonyms: CTSS; cathepsin S; EC 3.4.22.27; FLJ50259; MGC3886. Enzyme Commission Number: EC 3.4.22.27. CAS No. 71965-46-3. Purity: > 90% by SDS-PAGE. CTSS. Mole weight: 23.9 kDa (115-331 aa). Activity: >2000 mU/mg. Storage: Stable for at least 1 year as supplied. Briefly spin down the vial and reconstitute in 50 mM sodium acetate, 100 mM NaCl (pH 5.5) to 0.1-1 mg/ml and store at -80°C. Avoid repeated freeze and thaw cycles. Form: Lyophilized from proprietary buffer. Source: E. coli. Species: Human. CTSS; cathepsin S; EC 3.4.22.27; FLJ50259; MGC3886. Cat No: NATE-1702. | |
| Cathepsin S inhibitor | Cathepsin S is expressed in antigen-presenting cells and plays a role in invariant chain processing and major histocompatibility complex class II (MHCII) antigen presentation leading to CD4+ T-cell activation. An oral Cathepsin S inhibitor that blocks MHCII antigen presentation could result in a T-cell-selective immunosuppressant agent with improved safety over the current standard of care for the treatment of rheumatoid arthritis, psoriasis, multiple sclerosis and other autoimmune-based inflammatory diseases. Synonyms: LY3000328; LY-3000328; LY 3000328. Cathepsin S inhibitor. Grades: >98%. CAS No. 1373215-15-6. Molecular formula: C25H29FN4O5. Mole weight: 484.52. | |
| Cathepsin S Substrate, Fluorogenic | An internally quenched, highly cathepsin S-selective, fluorogenic peptide substrate that is efficiently cleaved by CatS, but not by Cathepsin B & L. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-Cathepsin K antibody produced in mouse | ~2 mg/mL, clone CL124-1H6, purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Native Bovine Cathepsin B | Cathepsin B has been found to cleave procaspase 1 and procaspase 11 and to induce apoptosis in digitonin-permeabilized cells. Translocation of cathepsin B from the cytoplasm to the nucleus contributes to bile salt induced apoptosis of Rat hepatocytes. Levels of cathepsin B in PC12 cells significantly decrease 12 to 24 hours after apoptosis is induced. Group: Enzymes. Synonyms: CTSB; cathepsin B; 9047-22-7; APPS; CPSB; cathepsin B1 (obsolete); cathepsin II. CAS No. 9047-22-7. Cathepsin B. Activity: > 10 units/mg protein. Form: Lyophilized powder containing sodium phosphate, sodium chloride and ~6% EDTA as stabilizer. Source: Bovine spleen. Species: Bovine. CTSB; cathepsin B; 9047-22-7; APPS; CPSB; cathepsin B1 (obsolete); cathepsin II. Cat No: NATE-0167. | |
| Native Bovine Cathepsin C | Cathespin C is a dipeptidyl aminopeptidase that can sequentially remove dipeptides from a peptide chain with an unsubstituted N-terminus. The enzyme exhibits a preference for glycine and proline as N-terminal aminoacids. Substrates that have an N-terminal lysyl or arginyl residue, or a penultimate proryl residue are not targeted by this enzyme. The endopeptidase activity requires the presence of halide ions and sulfydryl activators. Applications: Cathepsin c has been used in a study that demonstrated the potential of a proteomics approach to identify novel proteins expressed by extravillous trophoblast and to uncover the mechanisms leading to disease states in pregnancy. catheps...s. Synonyms: CTSC; cathepsin C; 9032-68-2; EC 3.4.14.1; dipeptidyl aminopeptidase I; dipeptidyl transferase; dipeptidyl transferase; dipeptide arylamidase I; DAP I; dipeptidyl-peptidase I; DPP-I; CPPI; DPP1; DPPI; HMS; JP; JPD; PALS; PDON1; PLS. Enzyme Commission Number: EC 3.4.14.1. CAS No. 9032-68-2. CTSC. Activity: > 5 units/mg protein. Form: Lyophilized from a 1 M sodium chloride solution. Source: Bovine spleen. Species: Bovine. CTSC; cathepsin C; 9032-68-2; EC 3.4.14.1; dipeptidyl aminopeptidase I; dipeptidyl transferase; dipeptidyl transferase; dipeptide arylamidase I; DAP I; dipeptidyl-peptidase I; DPP-I; CPPI; DPP1; DPPI; HMS; JP; JPD; PALS; PDON1; PLS. Cat No: NATE-0170. | |
| Native Bovine Cathepsin D | Cathepsin D is an endosomal-lysosomal aspartic protease implicated in breast cancer metastasis and Alzheimers disease. Lysosomal release of cathepsin D has been found to precede cytochrome c release and loss of membrane potential in apoptotic Human foreskin fibroblasts. Cathepsin D levels in PC12 cells increase 12 to 24 hours after apoptosis is induced. Group: Enzymes. Synonyms: CTSD; cathepsin D; 9025-26-7; EC 3.4.23.5; CLN10; CPSD; HEL-S-130P. Enzyme Commission Number: EC 3.4.23.5. CAS No. 9025-26-7. CTSD. Mole weight: 45 kDa. Activity: > 2.0 units/mg protein. Form: Lyophilized powder containing Citrate buffer salts. Source: Bovine spleen. Species: Bovine. CTSD; cathepsin D; 9025-26-7; EC 3.4.23.5; CLN10; CPSD; HEL-S-130P. Cat No: NATE-0171. | |
| Native Human Cathepsin B | Cathepsin B has been found to cleave procaspase 1 and procaspase 11 and to induce apoptosis in digitonin-permeabilized cells. Translocation of cathepsin B from the cytoplasm to the nucleus contributes to bile salt induced apoptosis of rat hepatocytes. Levels of cathepsin B in PC12 cells significantly decrease 12 to 24 hours after apoptosis is induced. Group: Enzymes. Synonyms: CTSB; cathepsin B; cathepsin B1; APPS; CPSB; EC 3.4.22.1; 9047-22-7; cathepsin II; CatB. Enzyme Commission Number: EC 3.4.22.1. CAS No. 9047-22-7. Cathepsin B. Activity: > 2 ,000 units/mg protein (E1%/280). Storage: -20°C. Form: buffered aqueous solution. Solution in 50 mM sodium acetate, pH 5.0, with 1 mM EDTA. Source: Human liver. Species: Human. CTSB; cathepsin B; cathepsin B1; APPS; CPSB; EC 3.4.22.1; 9047-22-7; cathepsin II; CatB. Cat No: NATE-0168. | |
| Procathepsin B (26-50) (rat) | Procathepsin B (26-50) (rat) is completely resistant to proteolysis by cathepsin B even after incubation overnight. It inhibits human cathepsin B with a Ki of 2.8 μM and rat cathepsin B with a Ki of 2 μM. Synonyms: H-Ala-Gly-Arg-Asn-Phe-Tyr-Asn-Val-Asp-Ile-Ser-Tyr-Leu-Lys-Lys-Leu-Cys-Gly-Thr-Val-Leu-Gly-Gly-Pro-Lys-NH2; L-alanyl-glycyl-L-arginyl-L-asparagyl-L-phenylalanyl-L-tyrosyl-L-asparagyl-L-valyl-L-alpha-aspartyl-L-isoleucyl-L-seryl-L-tyrosyl-L-leucyl-L-lysyl-L-lysyl-L-leucyl-L-cysteinyl-glycyl-L-threonyl-L-valyl-L-leucyl-glycyl-glycyl-L-prolyl-L-lysinamide. Grades: ≥95%. CAS No. 317331-27-4. Molecular formula: C123H198N34O33S. Mole weight: 2713.16. | |
| 1,1,2-Ethanetricarboxylic Acid 1,1,2-Triethyl Ester | 1,1,2-Ethanetricarboxylic Acid 1,1,2-Triethyl Ester is a useful synthetic intermediate. It can be used to prepare Isobutylsuccinic Acid (I780660) which was used to synthesize succinimide derivatives as inhibitors of human leukocyte elastase, cathepsin G and proteinase 3. Group: Biochemicals. Grades: Highly Purified. CAS No. 7459-46-3. Pack Sizes: 5g, 10g. Molecular Formula: C11H18O6. US Biological Life Sciences. |  Worldwide |
| 1- (2-Hydroxyphenyl) -4- (tert-butoxycarbonyl) piperazine | 1- (2-Hydroxyphenyl) -4- (tert-butoxycarbonyl) piperazine is an intermediate used to synthesize 2-(1-Piperazinyl)-benzenethiol which is used to used to prepare 3,5-dioxo-(2H,4H)-1,2,4-triazine as 5-HT1AR ligands. 1- (2-Hydroxyphenyl) -4- (tert-butoxycarbonyl) piperazine is also used to prepare nonpeptidic biaryl inhibitors of human cathepsin K in relation to treatment of osteoporosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 313657-51-1. Pack Sizes: 1g, 10g. Molecular Formula: C15H22N2O3, Molecular Weight: 278.35. US Biological Life Sciences. | Worldwide |
| 1, ?2-?Piperidinedicarboxyl ?ic Acid 1-?(Phenylmethyl) Ester | 1, ?2-?Piperidinedicarboxyl ?ic Acid 1-?(Phenylmethyl) Ester is used to prepare disubstituted azetidinones as selective inhibitors of cysteine protease cathepsin K. It is also used to synthesize 2-?[(R)?-?2-?methylpyrrolidin-?2-?yl]?-?1H-?benzimidazole-?4-?carboxamide (ABT-?888) as the Poly(ADP-?ribose) Polymerase (PARP) inhibitor for the treatment of cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 28697-07-6. Pack Sizes: 25g, 100g. Molecular Formula: C14H17NO4, Molecular Weight: 263.29. US Biological Life Sciences. | Worldwide |
| 1,3-Bis-(Z-Leu-Leu)-diaminoacetone | 1,3-Bis-(Z-Leu-Leu)-diaminoacetone, a cysteine protease inhibitor, can specifically and efficiently inhibit the processing of p-Prl signal peptide (IC50 ca. 50 nM) without affecting the activity of signal peptidase and lysosomal cathepsin, proteasome, and other proteases. Synonyms: (Z-LL)2 Ketone; Z-Leu-Leu-NH-CH2-CO-CH2-NH-Leu-Leu-Z; 2,2'-(2-Oxo-1,3-propanediyl)bis[N-[(phenylmethoxy)carbonyl]-L-leucyl-L-leucinamide; 1,3-di-(N-carboxybenzoyl-leucyl-leucyl)aminoacetone; Dibenzyl [(4S,7S,15S,18S)-7,15-diisobutyl-2,20-dimethyl-5,8,11,14,17-pentaoxo-6,9,13,16-tetraazahenicosane-4,18-diyl]biscarbamate. Grades: ≥95%. CAS No. 313664-40-3. Molecular formula: C43H64N6O9. Mole weight: 809.00. | |
| [1- (4-Bromophenyl) cyclopropyl]methanol | Used for preparation of amino acid derivatives as cathepsin cysteine protease inhibitors. Group: Biochemicals. Alternative Names: 1-(4-Bromophenyl)-1-cyclopropanemethanol; 1- (p-Bromophenyl) cyclopropanemethanol. Grades: Highly Purified. CAS No. 98480-31-0. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 1-Naphthalenylsulfonyl-Ile-Trp-aldehyde | 1-Naphthalenylsulfonyl-Ile-Trp-aldehyde is a potent, reversible, selective and cell-permeable cathepsin L inhibitor with an IC50 of 1.9 nM. It inhibits the release of bone Ca2+ and hydroxyproline in vitro and is useful in the treatment of osteoporosis. Synonyms: N-(1-Naphthalenylsulfonyl)-Ile-Trp-aldehyde; Pentanamide, N-[(1S)-1-formyl-2-(1H-indol-3-yl)ethyl]-3-methyl-2-[(1-naphthalenylsulfonyl)amino]-, (2S,3S)-; N-[(2S)-1-(1H-Indol-3-yl)-3-oxo-2-propanyl]-N2-(1-naphthylsulfonyl)-L-isoleucinamide; N-(1Naphthalenylsulfonyl)-IW-CHO; Cathepsin L Inhibitor IV. Grades: ≥95%. CAS No. 161709-56-4. Molecular formula: C27H29N3O4S. Mole weight: 491.61. | |
| 1-Pyrrolidinyl-3-pyridineacetic Acid | 1-Pyrrolidinyl-3-pyridineacetic Acid is a reagent that is used in the synthesis of phenylalanine cyanomethylamides as cathepsin B inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 933760-99-7. Pack Sizes: 10mg, 100mg. Molecular Formula: C12H15NO2, Molecular Weight: 205.25. US Biological Life Sciences. | Worldwide |
| 1- (t-Butoxycarbonyl) aminocyclobutanecarboxylic acid | Boc-1-aminocyclobutane-1-carboxylic Acid is used in the synthesis of dipeptidyl nitriles with cathepsin-inhibiting activities. It is also used to prepare alkyl-oxo-aryl amides as novel antagonists of TRPA1 receptor. Synonyms: Boc-Acb(1)-OH; N-Boc-1-Aminocyclobutanecarboxylic acid; 1-(Boc-amino)cyclobutanecarboxylic Acid; 1- ( (tert-Butoxycarbonyl) amino) cyclobutanecarboxylic acid; 1-[(2-methylpropan-2-yl)oxycarbonylamino]cyclobutane-1-carboxylic acid; N-α-(t-Butoxycarbonyl)cyclovaline. Grades: ≥ 95% (Assay). CAS No. 120728-10-1. Molecular formula: C10H17NO4. Mole weight: 215.25. | |
| 1-[ (tert-Butyloxycarbonyl) amino]propane-2, 3-diol | 1-[ (tert-Butyloxycarbonyl) amino]propane-2, 3-diol is a reagent used in the synthesis of analogs of Vestipitant, potent and orally NK1 antagonists. Also, it is the used in the synthesis of N-Boc-2-aminoacetaldehyde (B600600), which is used in the synthesis of carbohydrates as well as studies relating to inhibitors of cathepsin K. Group: Biochemicals. Grades: Highly Purified. CAS No. 137618-48-5. Pack Sizes: 250mg, 1g. Molecular Formula: C8H17NO4, Molecular Weight: 191.22. US Biological Life Sciences. | Worldwide |
| 2-(1-Piperazinyl)-phenol Dihydrochloride | 2-(1-Piperazinyl)-phenol Dihydrochloride, is used to prepare nonpeptidic biaryl inhibitors of human cathepsin K in relation to treatment of osteoporosis. It is also used to synthesize serotonin transporters/histamine H3 receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 667864-86-0. Pack Sizes: 1g, 10g. Molecular Formula: C10H14N2O 2HCl. US Biological Life Sciences. | Worldwide |
| 2,3,4-Trimethyl-3-pentanol | 2,3,4-Trimethyl-3-pentanol is used to prepare cathepsin K inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 3054-92-0. Pack Sizes: 1g, 5g. Molecular Formula: C8H18O, Molecular Weight: 130.229999999999. US Biological Life Sciences. | Worldwide |
| 2,3-Dichloro-D-β-homophenylglycine | 2,3-Dichloro-D-β-homophenylglycine is used as a reactant in the preparation of (thiazolylcarbonylamino)propionic acid derivatives as cathepsin A inhibitors. Synonyms: H-D-Phg(2,3-Cl2)-(C#CH2)OH; H-D-β-Phe(2,3-Cl2)-OH; (S)-3-Amino-3-(2,3-dichlorophenyl)propanoic acid. Grades: ≥ 98% (HPLC). CAS No. 748128-13-4. Molecular formula: C9H9Cl2NO2. Mole weight: 234.08. | |
| 2,5-Difluorobenzoic acid | 2,5-Difluorobenzoic Acid acts as a reagent in the synthesis of rutaecarpine and analogs used for the removal of caffeine from the body. Prepparation of quinolone carboxylic acids as cell-permeable inhibitors of protein tyrosine phosphatase (Erratum). Preparation, molecular docking, and bioactivity of α-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis. Also used as new passive water tracers for oil field applications. Synonyms: NSC 190310; 5-Difluorobenzoic acid; 2,5-difluorobenzoate. Grades: ≥95%. CAS No. 2991-28-8. Molecular formula: C7H4F2O2. Mole weight: 158.10. | |
| 2-Amino-2-oxo-acetic Acid Ethyl Ester | 2-Amino-2-oxo-acetic Acid Ethyl Ester is a reagent used to prepare methanotetra hydroiso quinolinecarboxyl ic acid. It can also be used in preparation of 1,2,4-Thiadiazole, a Cathepsin B inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 617-36-7. Pack Sizes: 5g, 10g. Molecular Formula: C4H7NO3, Molecular Weight: 117.1. US Biological Life Sciences. | Worldwide |
| 2-Chloro-3- (trifluoromethyl) benzoic Acid | 2-Chloro-3- (trifluoromethyl) benzoic Acid is a reactant in the preparation of trifluoromethylphenyl as P2 for ketoamide-based cathepsin S inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 39226-97-6. Pack Sizes: 1g, 10g. Molecular Formula: C8H4ClF3O2, Molecular Weight: 224.56. US Biological Life Sciences. | Worldwide |
| 2-Chloro-N-methoxy-N-methylbenzamide | 2-Chloro-N-methoxy-N-methylbenzamide was used as a reagent in the synthesis of functionalized β-oxonitriles. Also used in the synthesis of potent thiosemicarbazone based cathepsin L inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 289686-74-4. Pack Sizes: 500mg, 1g. Molecular Formula: C9H10ClNO2, Molecular Weight: 199.63. US Biological Life Sciences. | Worldwide |
| 2-Pyrimidinecarbonitrile | Cathepsin K is a lysosomal cysteine protease found in osteoclasts whose elevated activity has been linked to the formation of osteoporosis and arthritis. 2-cyano-Pyrimidine is a cathepsin K inhibitor. Synonyms: pyrimidine-2-carbonitrile. Grades: 95+%. CAS No. 14080-23-0. Molecular formula: C5H3N3. Mole weight: 105.10. | |
| (2R,?3R)?-2-Bromo-3-hydroxybutanedioic Acid 1,4-Diethyl Ester | (2R,?3R)?-2-Bromo-3-hydroxybutanedioic Acid 1,4-Diethyl Ester is an intermediate in the synthesis of derivative of E-64 an inhibitor of cathepsins B and L as well as a potential inhibitor of calpain. Group: Biochemicals. Grades: Highly Purified. CAS No. 80640-15-9. Pack Sizes: 1g, 5g. Molecular Formula: C8H13BrO5. US Biological Life Sciences. | Worldwide |
| (2R)-4-Phenylbutan-2-amine-d3 | (2R)-4-Phenylbutan-2-amine is an isotope labelled intermediate in the synthesis of potent Cathepsin S inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C10H12D3N. US Biological Life Sciences. | Worldwide |
| (2R)-4-Phenylbutan-2-amine p-Toluenesulfonic Acid | (2R)-4-Phenylbutan-2-amine p-Toluenesulfonic Acid is an intermediate in the synthesis of potent Cathepsin S inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C17H23NO3S. US Biological Life Sciences. | Worldwide |
| (2S, 3S) -3- [ [ [ (1S) -1- [ [ (4-Azidobutyl) amino] carbonyl] -3-methylbutyl] amino] carbonyl] -2-oxiranecarboxylic Acid Ethyl Ester | N3Le is a derivative of E-64 an inhibitor of cathepsins B and L as well as a potential inhibitor of calpain. E-64d has been shown to inhibit lysosomal proteases. Group: Biochemicals. Grades: Highly Purified. CAS No. 1174021-95-4. Pack Sizes: 1mg, 10mg. Molecular Formula: C16H27N5O5. US Biological Life Sciences. | Worldwide |
| 3-Cyano-1,2,4-triazole | A cyano substituted triazole with inhibitory effects on cathepsin K used in a study of the electrophilicity and reactivity of diverse nitrile-containing compounds and its correlation to the mechanism-of-action. Group: Biochemicals. Alternative Names: 1H-1,2,4-Triazole-3-carbonitrile; s-Triazole-3-carbonitrile. Grades: Highly Purified. CAS No. 3641-10-9. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| 3-epi-Ursolic Acid | 3-epi-Ursolic Acid is a potent inhibitor against glycogen phosphorylase which makes it a potential rug for treatment of type-2 diabetes and other diseases associated with glycogen metabolism. It is also a part of the group of triterpenoids that act as novel inhibitors of Human Cathepsin L. Group: Biochemicals. Grades: Highly Purified. CAS No. 989-30-0. Pack Sizes: 5mg, 10mg. Molecular Formula: C30H48O3, Molecular Weight: 456.7. US Biological Life Sciences. | Worldwide |
| 3-Iodo-N-[(benzyloxy)carbonyl]-L-tyrosine | 3-Iodo-N-[(benzyloxy)carbonyl]-L-tyrosine is a reactant used in the preparation of diazonamide A and peptidyl and azapeptidyl Me ketones as substrate analog inhibitors of papain and cathepsin B. Group: Biochemicals. Alternative Names: 3-Iodo-N-[ (phenylmethoxy) carbonyl]-L-tyrosine. Grades: Highly Purified. CAS No. 79677-62-6. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 3-Methyl-D-phenylalanine | 3-Methyl-D-phenylalanine is a derivative of D-Phenylalanine and is used as a reagent in the synthesis of aminophenylpropanyl phosphate derivatives which can exhibit pin1 inhibitory activity. 3-Methyl-D-phenylalanine is also used in the preparation of N-arylaminonitriles which are useful as bioavailable peptidomimetic inhibitors of cathepsin B. Synonyms: D-Phe(3-Me)-OH; m-Methyl-D-phenylalanine; (R)-2-Amino-3-(3-methylphenyl)propanoic acid; (R)-2-Amino-3-(m-tolyl)propanoic acid; D-3-Methylphenylalanine; D-PHENYLALANINE, 3-METHYL-; 3-Methy-D-Phenylalanine; H-D-PHE(3-ME)-OH; (2R)-2-amino-3-(3-methylphenyl)propanoic acid; (R)-2-amino-3-m-tolylpropanoic acid. Grades: ≥ 99% (HPLC). CAS No. 114926-39-5. Molecular formula: C10H13NO2. Mole weight: 179.22. | |
| 5-Nitro-8-hydroxyquinoline | 5-Nitro-8-hydroxyquinoline is an antimicrobial agent used for the treatment of urinary tract infection. 5-Nitro-8-hydroxyquinoline is also a potent and reversible inhibitor of cathepsin B. 5-Nitro-8-hydroxyquinoline has been shown to have anti-cancer activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 4008-48-4. Pack Sizes: 10g, 25g, 100g, 250g. Molecular Formula: C?H?N?O?, Melting Point: >179ºC (dec.). US Biological Life Sciences. | Worldwide |
| Abz-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (669-674)-EDDnp | Abz-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (669-674)-EDDnp is an intramolecularly quenched fluorescent substrate with the ortho-aminobenzoyl (Abz)/N-(2,4-dinitrophenyl)ethylenediamine (EDDnp) groups as the donor/acceptor pair. It corresponds to the Swedish-mutated (JMV2236) β-amyloid precursor protein (βAPP) sequence, which is targeted by β-secretase BACE (β-site APP-cleaving activity). It is more selectively cleaved by BACE1 and BACE2 than by cathepsin D, a disintegrin and metalloprotease 10 (ADAM10), tumor necrosis α-converting enzyme (TACE), presenilin-1 (PS1), or presenilin-2 (PS2). Synonyms: JMV2236; L-α-Glutamine, N-(2-aminobenzoyl)-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-N-[2-[(2,4-dinitrophenyl)amino]ethyl]-; N-(2-Aminobenzoyl)-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-N-{2-[(2,4-dinitrophenyl)amino]ethyl}-L-α-glutamine. Grades: ≥95%. CAS No. 1007306-20-8. Molecular formula: C42H58N12O16. Mole weight: 986.99. | |
| Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-OH | Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-OH is a very efficient and selective FRET substrate for human cathepsin B (Km = 5.9 μM, kcat = 43 s-1, kcat/Km = 7288 mM-1s-1), with kcat/Km values of 133.3, 100, 32, 17, and 75 mM-1s-1 for cathepsin K, L, V, X, and cruzain, respectively. Synonyms: H-2Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-OH; Abz-GIVRAK(Dnp); L-Lysine, N-(2-aminobenzoyl)glycyl-L-isoleucyl-L-valyl-L-arginyl-L-alanyl-N6-(2,4-dinitrophenyl)-; N-(2-Aminobenzoyl)glycyl-L-isoleucylvalyl-L-arginyl-L-alanyl-N6-(2,4-dinitrophenyl)-L-lysine. Grades: ≥95%. CAS No. 827044-38-2. Molecular formula: C41H61N13O12. Mole weight: 928.02. | |
| Ac-Glu-Asp(EDANS)-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Gly-Lys(DABCYL)-Glu-NH2 | Ac-Glu-Asp(EDANS)-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Gly-Lys(DABCYL)-Glu-NH2 is a sensitive fluorescent (FRET) peptide substrate for cathepsin D. This enzyme degrades extracellular matrix components and may promote the spread of tumor cells. High levels of active cathepsin D were found in senile plaques in the brains of Alzheimer's patients. Synonyms: L-α-Glutamine, N-acetyl-L-α-glutamyl-N-[2-[(5-sulfo-1-naphthalenyl)amino]ethyl]-L-asparaginyl-L-lysyl-L-prolyl-L-isoleucyl-L-leucyl-L-phenylalanyl-L-phenylalanyl-L-arginyl-L-leucylglycyl-N6-[4-[[4-(dimethylamino)phenyl]azo]benzoyl]-L-lysyl-; N-Acetyl-L-α -glutamyl-N-{2-[ (5-sulfo-1-naphthyl) amino]ethyl}-L-asparaginyl-L-lysyl-L-prolyl-L-isoleucyl-L-leucyl-L-phenylalanyl-L-phenylalanyl-L-arginyl-L-leucylglycyl-N6- (4-{[4- (dimethylamino) phenyl]diazenyl}benzoyl) -L-lysyl-L-α -glutamine. Grades: ≥95%. CAS No. 400716-78-1. Molecular formula: C104H146N24O23S. Mole weight: 2132.52. | |
| Ala-Ala-OMe HCl | Substrate for dipeptidyl aminopeptidase I (cathepsin C). Synonyms: L-Alanyl-L-alanine methyl ester hydrochloride. Grades: ≥ 98% (TLC). CAS No. 41036-19-5. Molecular formula: C7H14N2O3·HCl. Mole weight: 210.66. | |
| ALLM - CAS 110115-07-6 | Cell permeable inhibitor of calpain I (Ki = 120 nM), calpain II (Ki = 230 nM), cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 600 pM). Group: Fluorescence/luminescence spectroscopy. | |
| ALLN - CAS 110044-82-1 | Cell-permeable inhibitor of calpain I (Ki = 190 nM), calpain II (Ki = 220 nM), cathepsin B (Ki = 150 nM), and cathepsin L (Ki = 500 pM). Group: Fluorescence/luminescence spectroscopy. | |
| Aloxistatin | Aloxistatin is an inhibitor of cathepsins B and L as well as a potential inhibitor of calpain, which predicted to function against SARS-CoV-2 infection. Synonyms: L-trans-Epoxysuccinyl(OEt)-Leu-3-methylbutylamide; L-trans-Epoxysuccinyl-Leu-3-methylbutylamide-ethyl ester; (2S, 3S) -3-[[[ (1S) -3-Methyl-1-[[ (3-methylbutyl) amino]carbonyl]butyl]amino]carbonyl]-2-oxiranecarboxylic Acid Ethyl Ester; E 64c ethyl ester; E 64d; EP 453; EST; Loxistatin; NSC 694281; (2S,3S)-trans-Epoxysuccinyl-L-leucylamido-3-methylbutane ethyl ester. Grades: 98%. CAS No. 88321-09-9. Molecular formula: C17H30N2O5. Mole weight: 342.43. | |
| Aminopeptidase N Inhibitor | Membrane alanyl aminopeptidase is also known as alanyl aminopeptidase (AAP) or aminopeptidase N (AP-N), which is an enzyme that in humans is encoded by the ANPEP gene. Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 μM). It is selective for AP-N/CD13 over matrix metalloproteinase-9 (MMP-9), angiotensin converting enzyme (ACE), neutral endopeptidase (NEP), γ-glutamyl transpeptidase, and the serine proteases dipeptidyl peptidase 4 (DPP-4) and cathepsin G at a concentration of 1 mM. AP-N inhibitor is non-cytotoxic to U937 cells at a concentration of 100 μM. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. Synonyms: AP-N Inhibitor. Grades: ≥95%. CAS No. 596108-59-7. Molecular formula: C17H10N2O8. Mole weight: 370.27. | |
| AZD3839 free base | AZD3839 free base is a potent and selective orally active, brain-permeable BACE1 inhibitor ( K i=26 nM). AZD3839 free base shows 14 and >1000-fold selectivity against BACE2 and cathepsin D, respectively. AZD3839 free base exhibits dose- and time-dependent lowering of plasma, brain, and cerebrospinal fluid Aβ levels in mouse, guinea pig, and non-human primate. AZD3839 free base can be used for the research of Alzheimer's disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1227163-84-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-13438. | |
| Baker's yeast (S. cerevisiae) Carboxypeptidase Y, recombinant | Carboxypeptidase Y (CPY) catalyzes the following reaction: Peptidyl-L-amino acid + H2O ------> Peptide + L-amino acid.It is prepared according to the method of Moore & Stein (J. Biol Chem, 211, 907, 1954). It resembles Carboxypeptidase A in its substrate specificity, but it hydrolyzes C-terminal glycine and L-leuicine more rapidly and L-phenylalanine more slowly. Group: Enzymes. Synonyms: carboxypeptidase Y; serine carboxypeptidase I; cathepsin A; lysosomal protective protein; deamidase; lysosomal carboxypeptidase A; phaseolin; EC 3.4.16.5; 9046-67-7; Peptidyl-L-amino acid Hydrolase; Serine Carboxypeptidase; Carboxypeptidase C; Peptidyl-L. Enzyme Commission Number: EC 3.4.16.1. Purity: > 90 %. Carboxypeptidase Y. Activity: > 10u/mg. Appearance: Clear, colorless to lightly colored. Storage: Long term below -20°C, short term 2-8°C. Avoid multiple freeze-thaws. Form: 500 mM sodium chloride, 500 mM imidazole, 20 mM sodium phosphate monobasic, 20 mM sodium phosphate dibasic, pH 7.5. Species: S. cerevisiae. carboxypeptidase Y; serine carboxypeptidase I; cathepsin A; lysosomal protective protein; deamidase; lysosomal carboxypeptidase A; phaseolin; EC 3.4.16.5; 9046-67-7; Peptidyl-L-amino acid Hydrolase; Serine Carboxypeptidase; Carboxypeptidase C; Peptidyl-L-amino-acid (-L-proline ) hydrolase; EC 3.4.12.8. Cat No: NATE-0103. | |
| Balicatib | The cathepsin K inhibitor AAE-581 (balicatib) as the most advanced of them passed Phase II clinical trials in 2005. Eighty adult female Macaca fascicularis underwent bilateral ovariectomies and were dosed twice daily by oral gavage with balicatib at 0, 3, 10, and 50 mg/kg for 18 months (groups O, L, M, H, respectively). Approximately 1 month after treatment initiation, the 50 mg/kg dose was decreased to 30 mg/kg. Twenty animals underwent sham-ovariectomies (group S). Bone mass was measured at 3-6 month intervals. At 18 months, vertebra and femur were collected for histomorphometry. Synonyms: AAE581; AAE-581; AAE 581. Grades: 0.98. CAS No. 354813-19-7. Molecular formula: C23H33N5O2. Mole weight: 411.54. | |
| β-Cyclopentyl-L-alanine | β-Cyclopentyl-L-alanine is used as a reagent in the synthesis of functionalized N-arylaminoethyl amides as noncovalent inhibitors of cathepsin S. Synonyms: β-Cyclopentyl-L-Ala-OH; (S)-2-Amino-3-cyclopentylpropanoic acid; 3-Cyclopentane-L-alanine; L-3-Cyclopentylalanine; H-Cpa-OH; (2S)-2-amino-3-cyclopentylpropanoic acid; 3-cyclopentylalanine; H-Ala(cPen)-OH; (S)-alfa-Amino-cyclopentanepropanoic acid; beta-cyclopentyl-l-alanine; beta-Cyclopentyl-L-Ala-OH; H Cpa OH. Grades: ≥ 99.5%. CAS No. 99295-82-6. Molecular formula: C8H15NO2. Mole weight: 157.09. | |
| Biotin-FF-FMK | Biotin-FF-FMK is a biotin-labeled cathepsin inhibitor that selectively suppresses cathepsin B and cathepsin L. Synonyms: Biotin-Phe-Phe-CH2F; Biotin-Phe-Phe-Fluoromethylketone. Grades: ≥95%. Molecular formula: C29H35FN4O4S. Mole weight: 554.68. | |
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