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Chlorambucil (marketed as Leukeran by GlaxoSmithKline) is a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia. It is a nitrogen mustard alkylating agent and can be given orally. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system. Synonyms: gamma-(p-bis(2-chloroethyl)aminophenyl)butyric acid. Grade: >98%. CAS No. 305-03-3. Molecular formula: C14H19Cl2NO2. Mole weight: 304.21.
One of the isotopic labelled form of Chlorambucil, which is an alkylating agent and could be used in chronic lymphocytic leukemia therapy. Synonyms: 4-[Bis(2-chloroethyl)amino]benzenebutanoic Acid-d8; 4-[p-[Bis(2-chloroethyl)amino]phenyl]butyric Acid-d8; Ambochlorin-d8; Amboclorin-d8; Ecloril-d8; Leukeran-d8; Leukeran Tablets-d8; Linfolizin-d8. Grade: 95% by HPLC; 98% atom D. Molecular formula: C14H11D8Cl2NO2. Mole weight: 312.26.
Chlorambucil Impurity 1
meta-Chlorambucil is an impurity of Chlorambucil; an alkylating agent that is used as a chemotherapy drug in the treatment of chronic lymphocytic leukemia. Synonyms: 3-[Bis(2-chloroethyl)amino]benzenebutanoic Acid; Chlorambucil Impurity. Grade: > 95%. CAS No. 134862-11-6. Molecular formula: C14H19Cl2NO2. Mole weight: 304.22.
Chlorambucil Impurity A
N-(2-Hydroxyethyl) Chlorambucil is a degradation product of Chlorambucil; an alkylating agent used as a chemotherapy drug in the treatment of chronic lymphocytic leukemia. Chlorambucil is also used to treat non-Hodgkin's lymphoma (NHL) and Hodgkin's disease. Synonyms: 4-[(2-Chloroethyl)(2-hydroxyethyl)amino]benzenebutanoic Acid; 4-[p-[(2-Chloroethyl)(2-hydroxyethyl)amino]phenylbutyric Acid; 4-[4-N-(2-Chloroethyl)-N-(2-hydroxyethyl)aminophenyl]butyric Acid; NSC 119101; Chlorambucil Impurity. Grade: > 95%. CAS No. 27171-89-7. Molecular formula: C14H20ClNO3. Mole weight: 285.77.
Chlorambucil Impurity B
N-Des-(2-chloroethyl) Chlorambucil is the half-mustard analog of Chlorambucil and exhibits mutagenic activity. Synonyms: 4-[(2-Chloroethyl)amino]benzenebutanoic Acid; Chlorambucil Impurity. Grade: > 95%. CAS No. 116505-53-4. Molecular formula: C12H16ClNO2. Mole weight: 241.72.
3,4-Dehydro Chlorambucil
(E)-4-[4-[Bis(2-chloroethyl)amino]phenyl]-3-butenoic Acid is a metabolite of Chlorambucil, a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia. Synonyms: 3,4-Dehydro Chlorambucil. Grade: > 95%. CAS No. 73027-06-2. Molecular formula: C14H17Cl2NO2. Mole weight: 302.2.
2-Fluoroadenosine
Fludarabine is highly effective in the treatment of chronic lymphocytic leukemia, producing higher response rates than alkylating agents such as chlorambucil alone.Fludarabine is used in various combinations with cyclophosphamide, mitoxantrone, dexamethasone and rituximab in the treatment of indolent non-Hodgkins lymphomas. As part of the FLAG regimen, fludarabine is used together with cytarabine and granulocyte colony-stimulating factor in the treatment of acute myeloid leukaemia. Because of its immunosuppressive effects, fludarabine is also used in some conditioning regimens prior to non myeloablative allogeneic stem cell transplant. Synonyms: Fludarabine; 2-Fluoro Adenosine; 6-Amino-2-fluoro-9-beta-D-ribofuranosylpurine. Grade: 98%. CAS No. 146-78-1. Molecular formula: C10H12FN5O4. Mole weight: 285.235.
4-[Bis (2-chloroethyl) aminophenyl]butyric acid
4-[Bis (2-chloroethyl) aminophenyl]butyric acid. Group: Biochemicals. Alternative Names: Chlorambucil. Grades: Highly Purified. CAS No. 305-03-3. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C14H19Cl2NO2. US Biological Life Sciences.
Worldwide
Atrimustine
Atrimustine is a conjugate of chlorambucil and β-estradiol benzoate with the antitumor activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bestrabucil; KM2210. CAS No. 75219-46-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101604.