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Chloroquine phosphate is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine phosphate is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine phosphate is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro ( EC 50 =1.13 μM) [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 50-63-5. Pack Sizes: 100 mg; 200 mg; 500 mg. Product ID: HY-17589.
Chloroquine phosphate
Chloroquine phosphate is an antimalarial drug and weak intercalating agent. It inhibits TLR signalling in plasmacytoid dendritic cells (pDCs). It has been used in emergency of COVID-19. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: N4-(7-Chloro-4-quinolinyl)-N1,N1-dimethyl-1,4-pentanediamine diphosphate salt; Aralen diphosphate; C2301; C 2301; C-2301; Chloroquine Diphosphate. Grades: ≥98% (HPLC). CAS No. 50-63-5. Molecular formula: C18H32ClN3O8P2. Mole weight: 515.86.
Labeled anti-malarial drug. Substrate for MRP in multidrug resistant cell line and inhibits photoaffinity labelling of MRP by quinoline-based photoactive drug IAAQ. Group: Biochemicals. Alternative Names: N4-(7-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine-d4 Diphosphate Salt; Aralen-d4 diphosphate; Aralen-d4 Phosphate; Arechin-d4; Avloclor-d4; Bemaphate-d4; Chingamin-d4; Chingamin-d4 Phosphate; SN 7618-d4; Sanoquin-d4;Tanakan-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Chloroquine diphosphate
Chloroquine diphosphate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Hydroxychlorquine sulphate. Appearance: Yellow powder. CAS No. 50-63-5. Molecular formula: C18H32ClN3O8P2. Mole weight: 515.86. Purity: 0.98. IUPACName: 4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine;phosphoric acid. Canonical SMILES: CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl.OP(=O)(O)O.OP(=O)(O)O. Product ID: ACM50635-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: Chloroquine phosphate.
Chloroquine diphosphate salt
Chloroquine diphosphate salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N4-(7-Chloro-4-quinolyl)-N1,N1-diethyl-1,4-pentanediamine Diphosphate; Chloroquine phosphate; Chloroquine diphosphate; 7-Chloro-4-[4-(diethylamino)-1-methylbutylamino]quinoline Diphosphate; Chloroquine diphosphate salt. Appearance: White Solid. CAS No. 50-63-5. Molecular formula: C18H26ClN3·2H3PO4. Mole weight: 515.86. Purity: BP/EP/JP. IUPACName: 4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine;phosphoricacid. Canonical SMILES: CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl.OP(=O)(O)O.OP(=O)(O)O. ECNumber: 200-055-2. Product ID: ACM50635. Alfa Chemistry ISO 9001:2015 Certified.
Chloroquine Diphosphate Salt
Standard anti-malarial drug. Substrate for MRP in multidrug resistant cell line and inhibits photoaffinity labelling of MRP by quinoline-based photoactive drug IAAQ. Inhibits cell growth and induces cell death in numerous cancer cell lines; inhibits cell proliferation and viability and induces apoptosis in 4T1 mouse breast cancer cells in vitro. Exhibits antimetastatic activity. Also inhibits autophagy via a mechanism distinct from that of 3-methyladenine. Group: Biochemicals. Alternative Names: N4-(7-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine Diphosphate Salt; Aralen Diphosphate; Aralen Phosphate; Arechin; Avloclor; Bemaphate; Chingamin; Chingamin Phosphate; SN 7618; Sanoquin; Tanakan. Grades: Highly Purified. CAS No. 50-63-5. Pack Sizes: 1g, 5g, 10g, 25g. Molecular Formula: C??H??ClN?O?P?, Molecular Weight: 515.86. US Biological Life Sciences.
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(S)-(+)-Hydroxy chloroquine diphosphate
(S)-(+)-Hydroxy chloroquine diphosphate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (S)-2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol Phosphate. Product Category: Heterocyclic Organic Compound. CAS No. 158749-76-9. Molecular formula: C18H32ClN3O9P2. Mole weight: 531.86. Purity: 0.96. IUPACName: 2-[[(4S)-4-[(7-chloroquinolin-4-yl)amino]pentyl]-ethylamino]ethanol. Canonical SMILES: CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCO. Product ID: ACM158749769. Alfa Chemistry ISO 9001:2015 Certified. Categories: (S)-Hydroxychloroquine.
Chloroquine Dihydrochloride
Chloroquine diphosphateis an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine phosphate is an Autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine phosphate is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC50=1.13 μM). Synonyms: 1,?4-Pentanediamine, N4-(7-chloro-4-quinolinyl)?-N1,?N1-diethyl-, hydrochloride. Grades: > 95%. CAS No. 3545-67-3. Molecular formula: C18H28Cl3N3. Mole weight: 392.79.
Naphthoquine phosphate
Naphthoquine phosphate is a potent and orally active antimalarial agent. Naphthoquine phosphate has thorough killing function for various schizonts of plasmodia , including resistance of P. falciparum to Chloroquine [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 173531-58-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-17036.
1,4-Bis(3-(4-(7-chloroquinolin-4-yl)piperazin-1-yl)propyl)piperazine is used in the studies and in the synthesis of the antimalarial activity of some tripiperaquines. Also, used in the synthesis and characterization of impurities present in an antimalarial drug piperaquine phosphate. Group: Biochemicals. Grades: Highly Purified. CAS No. 86486-21-7. Pack Sizes: 5mg, 10mg. Molecular Formula: C36H46Cl2N8, Molecular Weight: 661.71. US Biological Life Sciences.
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Naphthoquine phosphate
Naphthoquine phosphate and artemisinine are two antimalarials developed in China. Both drugs have proven to be efficacious and well tolerated as monotherapy as well as in combination in patients suffering from malaria. The Co-naphthoquine, a novel antimalarial combination, is an oral fixed combination tablet of the naphthoquine phosphate and artemisinine. Artemisinin is characterised by a rapid onset of schizonticidal action and a short half-life. Parasite clearance is, however, often incomplete when it is employed as a single agent unless high dosages are used over several days, but such a regimen may reduce patient compliance and increase the danger of toxicity. Naphthoquine phosphate, by contrast, has a slower onset of action and a longer half-life, associated with a low recrudescence rate. Synonyms: 1-Naphthalenol, 4-[(7-chloro-4-quinolinyl)amino]-2-[[(1,1-dimethylethyl)amino]methyl]-5,6,7,8-tetrahydro-, phosphate (1:2) (salt); 2-((tert-butylamino)methyl)-4-((7-chloroquinolin-4-yl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol bis(phosphate); Naphthoquine diphosphate. Grades: >98%. CAS No. 173531-58-3. Molecular formula: C24H34ClN3O9P2. Mole weight: 605.94.