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CHM 1. Group: Biochemicals. Grades: Purified. CAS No. 154554-41-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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CHM 1
CHM 1 is an apoptosis inducer with potent antitumor activity in human hepatocellular carcinoma. It inhibits tubulin polymerization in vitro and in vivo, and results in cell cycle arrest at G2/M phase by activating Cdc2 kinase activity. CHM 1 also exhibits vascular targeting activity via upregulation of p53 and induction of death receptor (DR5)-mediated apoptosis in HUVEC cells. Uses: Antitumor agent. Synonyms: CHM-1; CHM 1; CHM1; NSC 656158; NSC-656158; NSC656158; 6-(2-Fluorophenyl)-1,3-dioxolo[4,5-g]quinolin-8(5H)-one. Grades: ≥99% by HPLC. CAS No. 154554-41-3. Molecular formula: C16H10FNO3. Mole weight: 283.25.
CHMFL-FLT3-122
CHMFL-FLT3-122 is a potent and selective FLT3 inhibitor (IC50 = 40 nM) with >10-fold and 170-fold selectivity for FLT3 over BTK kinase and c-KIT kinase. It causes apoptosis via cell cycle arrest in G0/G1 phase in vitro. In MV4-11 cell inoculated xenograft model, it suppressed tumor growth. Uses: Antitumor agent. Synonyms: CHMFL-FLT3-122; CHMFL FLT3 122; CHMFLFLT3122; 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-(dimethylamino)-ethanone. CAS No. 1839150-56-9. Molecular formula: C26H29N7O2. Mole weight: 471.55.
2-(2-Bromophenyl)-1,3-dioxolane
2-(2-Bromophenyl)-1,3-dioxolane. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-(2-Bromophenyl)-1,3-dioxolane, 34824-58-3, 2-Bromobenzaldehyde ethylene acetal, 1,3-Dioxolane, 2-(2-bromophenyl)-, SBB067486, AG-F-19508, 1-bromo-2-(1,3-dioxolan-2-yl)benzene, ZINC02530752, PubChem3729, ACMC-1CSYY, AC1LB8VT, SureCN252280, AC1Q26DX, 652652_ALDRICH, AC1Q255P, RARECHEM AL BP 0014, CTK4H3086, ATTERCOP-CHM AT108947, MolPort-001-768-368, ANW-27980. Product Category: Bromine Series. Appearance: Clear colorless to pale yellow liquid. CAS No. 34824-58-3. Molecular formula: C9H9BrO2. Mole weight: 229.07. Purity: 0.95. IUPACName: 2-(2-bromophenyl)-1,3-dioxolane. Density: 1.515g/cm³. Product ID: ACM34824583. Alfa Chemistry ISO 9001:2015 Certified.
2-Bromo-p-xylene
2-Bromo-p-xylene. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-Bromo-o-xylene, 1-Bromo-2,3-dimethylbenzene, 2,3-Dimethylbromobenzene, 576-23-8, 3-Bromo-1,2-dimethylbenzene, 2,3-Dimethyl bromobenzene, Benzene, 1-bromo-2,3-dimethyl-, ST50406328, NSC76561, PubChem3766, Benzene, bromodimethyl-, AC1Q2DMF, ACMC-1CN3E, SureCN264714, AC1L29SS, AC1Q2N9S, B83789_ALDRICH, KSC223I3R, CTK1C3438, ATTERCOP-CHM AT107407. Product Category: Heterocyclic Organic Compound. CAS No. 35884-77-6. Molecular formula: C8H9Br. Mole weight: 185.1. Purity: 0.97. IUPACName: 1-bromo-2,3-dimethylbenzene. Canonical SMILES: CC1=C(C(=CC=C1)Br)C. ECNumber: 209-398-2. Product ID: ACM35884776. Alfa Chemistry ISO 9001:2015 Certified. Categories: 2,5-Dimethylbromobenzene.
3-Iodobenzyloxybenzene
3-Iodobenzyloxybenzene. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-Iodobenzyloxybenzene, 107623-21-2, 1-(Benzyloxy)-3-iodobenzene, 1-Benzyloxy-3-Iodobenzene, 1-iodo-3-phenylmethoxybenzene, ST51016225, ZINC00157048, PubChem3066, ACMC-1C7ZZ, SureCN314468, AC1N61WN, AC1Q4P8Z, 1-Benzyloxy-3-iodo-benzene, 1-Benzyl-Oxy-3-Iodobenzene, 532193_ALDRICH, 3-iodo-1-(phenylmethoxy)benzene, CTK4A5562, BENZYL 3-IODOPHENYL ETHER, 1-iodanyl-3-phenylmethoxy-benzene, ATTERCOP-CHM AT130335. Product Category: Ethers. Appearance: solid. CAS No. 107623-21-2. Molecular formula: C13H11IO. Mole weight: 310.13. Purity: 0.96. IUPACName: 1-iodo-3-phenylmethoxybenzene. Canonical SMILES: C1=CC=C(C=C1)COC2=CC(=CC=C2)I. Density: 1.58g/cm³. ECNumber: 926-005-6. Product ID: ACM107623212. Alfa Chemistry ISO 9001:2015 Certified.
5-(Carboxyhydroxymethyl)uridine methyl ester is a crucial compound widely used in biomedical research. It is primarily utilized for the synthesis of modified nucleosides, nucleotides, and oligonucleotides. This compound plays a vital role in molecular biology and drug discovery, particularly in the development of antiviral drugs. Synonyms: 5-(1-Hydroxy)(methoxycarbonyl)methyl uridine; 1,?2,?3,?4-Tetrahydro-a-hydroxy-2,?4-dioxo-1-b-D-ribofuranosyl-5-pyrimidineacetic acid methyl ester; Methyl 2-(1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-hydroxyacetate; Chmu-methyl ester; 5-(1-Hydroxy-2-methoxy-2-oxoethyl)uridine. Grades: ≥95%. CAS No. 945684-13-9. Molecular formula: C12H16N2O9. Mole weight: 332.26.
AB-CHMINACA metabolite M4-d4
AB-CHMINACA metabolite M4-d4 is a deuterium labelled metabolite of AB-CHMINACA which is a synthetic cannabinoid, structurally related to AB-CHMINACA metabolite M5A (A106010). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C15H14D4N2O2, Molecular Weight: 262.339999999999. US Biological Life Sciences.
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AB-CHMINACA metabolite M7
AB-CHMINACA metabolite M7 is an indazole-based synthetic cannabinoid (CB) that is structurally related to AB-FUBINACA, a high affinity ligand of the central CB1 receptor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500μg, 1mg. Molecular Formula: C20H25N3O5, Molecular Weight: 387.43. US Biological Life Sciences.
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BB-22 3-Carboxyindole Metabolite
BB-22 3-Carboxyindole Metabolite is an intermediate of MDMB-CHMICA (M199520). MDMB-CHMICA is an analogue of N-[(1S)-1-(Aminocarbonyl)-2-methylpropyl]-1-[(4-fluorophenyl)methyl]-1H-indazole-3-carboxamide (A603135), an indazole derivative developed as a CB1 receptor modulator used in the treatment of CB1-mediated diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 858515-71-6. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C16H19NO2. US Biological Life Sciences.
Worldwide
CHMFL-ABL-053
CHMFL-ABL-053 is a potent and orally available inhibitor of BCR-ABL (IC50 = 70 nM) without inhibitory activity against c-KIT kinase that is a common target of BCR-ABL inhibitors currently used. A pharmacokinetic study revealed that it had 4.3h of half-life and 24% bioavailability in rats. It is developed for the treatment of chronic myeloid leukemia (CML). Uses: The treatment of chronic myeloid leukemia (cml). Synonyms: CHMFL-ABL-053; CHMFL-ABL053; CHMFL-ABL 053. 2 - ((3-Amino-4-methylphenyl)amino) - N - (2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide. CAS No. 1808287-83-3. Molecular formula: C28H26F3N7O2. Mole weight: 549.56.
CHMFL-BMX-078
CHMFL-BMX-078 is a highly potent and selective type II irreversible BMX kinase inhibitor that exhibits an IC50 of 11 nM against BMX kinase and exhibits great selectivity over kinases such as BTK, JAK3, EGFR, and MAP2K7 that bore a structurally identical cysteine residue in BMX kinase. Uses: Protein kinase inhibitors. Synonyms: CHMFL-BMX-078; CHMFL-BMX 078;CHMFL BMX 078; CHMFLBMX078; 4- (methylamino) -2-[4-methyl-3- (prop-2-enoylamino) anilino]-N-[2-methyl-5-[ (3, 4, 5-trimethoxybenzoyl) amino]phenyl]pyrimidine-5-carboxamide; 2-((3-acrylamido-4-methylphenyl)amino)-N-(2-methyl-5-(3,4,5-trimethoxybenzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide. CAS No. 1808288-51-8. Molecular formula: C33H35N7O6. Mole weight: 625.67.
dTDP-4-dehydro-6-deoxy-α-D-gulose 4-ketoreductase
The enzyme forms an activated deoxy-α-D-allose, which is converted to mycinose after attachment to the aglycones of several macrolide antibiotics, including tylosin, chalcomycin, dihydrochalcomycin, and mycinamicin II. Group: Enzymes. Synonyms: dTDP-4-dehydro-6-deoxygulose reductase; tylD (gene name); gerKI (gene name); chmD (gene name); mydI (gene name). Enzyme Commission Number: EC 1.1.1.364. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0281; dTDP-4-dehydro-6-deoxy-α-D-gulose 4-ketoreductase; EC 1.1.1.364; dTDP-4-dehydro-6-deoxygulose reductase; tylD (gene name); gerKI (gene name); chmD (gene name); mydI (gene name). Cat No: EXWM-0281.
Formic acid,manganese salt
Formic acid,manganese salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Formic acid, manganese salt, EINECS 239-087-7, 14998-38-0. Product Category: Heterocyclic Organic Compound. CAS No. 14998-38-0. Molecular formula: CHMnO2+. Mole weight: 99.955489 [g/mol]. Purity: 0.96. IUPACName: manganese(2+) formate. Canonical SMILES: C(=O)[O-].[Mn+2]. ECNumber: 239-087-7. Product ID: ACM14998380. Alfa Chemistry ISO 9001:2015 Certified. Categories: MANGANESE(II) FORMATE.
isoliquiritigenin 2'-O-methyltransferase
Not identical to EC 2.1.1.65, licodione 2'-O-methyltransferase. While EC 2.1.1.154, isoliquiritigenin 2'-O-methyltransferase can use licodione as a substrate, EC 2.1.1.65 cannot use isoliquiritigenin as a substrate. Group: Enzymes. Synonyms: chalcone OMT; CHMT. Enzyme Commission Number: EC 2.1.1.154. CAS No. 139317-14-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1750; isoliquiritigenin 2'-O-methyltransferase; EC 2.1.1.154; 139317-14-9; chalcone OMT; CHMT. Cat No: EXWM-1750.