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| Product | Description | |
|---|---|---|
| Chromanol 293B | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. |  |
| Chromanol 293B | Chromanol 293B. Group: Biochemicals. Grades: Purified. CAS No. 163163-23-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Chromanol 293B | Chromanol 293B is a specific slow delayed rectifier K+ current (IKs) blocker with an IC50 value of 6.89 μM in xenopus oocytes expressing rat. It shows no activity at rat Kv1.1 or Kir2.1 channels at a concentration of 30 μM. It inhibits cystic fibrosis transmembrane conductance regulator (CTFR) Cl- currents (ICTFR) with an IC50 value of 19 μM in xenopus oocytes expressing human CTFR. It increases the extent and rate of IKs in guinea pig ventricular cells in a dose-dependent manner. It is a useful research chemical. Uses: Potassium channel blockers. Synonyms: rel-N-[(3R,4S)-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methyl-ethanesulfonamide; rel-N-[(3R,4S)-6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methylethanesulfonamide; trans-N-[6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methyl-ethanesulfonamide. Grades: ≥99% by HPLC. CAS No. 163163-23-3. Molecular formula: C15H20N2O4S. Mole weight: 324.39. |  |
| (-)-[3R,4S]-Chromanol 293B | (-)-[3R,4S]-Chromanol 293B. Group: Biochemicals. Grades: Purified. CAS No. 163163-24-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| (-)-[3R,4S]-Chromanol 293B | (-)-[3R,4S]-Chromanol 293B is one of the chromanols, which inhibits cAMP-mediated Cl- secretion in colon crypts by a blockade of a cAMP-activated K+ conductance. It selectively inhibits the slow component of delayed rectifier K+ current. It has negligible inhibitory action at KV11.1 (hERG) channels. It may be a useful research chemical. Uses: Potassium channel blockers. Synonyms: N-[(3R,4S)-6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methylethanesulfonamide. Grades: ≥99% by HPLC. CAS No. 163163-24-4. Molecular formula: C15H20N2O4S. Mole weight: 324.39. | |
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