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| Product | Description | |
|---|---|---|
| Chrysomycin B | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. |  |
| Chrysomycin B | Chrysomycin B is a minor analogue in a complex of C-glycoside antitumor active substances isolated from Streptomyces. Its activity is lower than that of its vinyl analogue (Chrysomycin A), but it still has strong anti-tumor activity and is an inhibitor of the catalytic activity of human topoisomerase II. It can be used as a light-activated cross-linking agent for DNA and histones. Synonyms: Chrysomycin M; Virenomycin M; Albacarcin M. Grades: >98% by HPLC. CAS No. 83852-56-6. Molecular formula: C27H28O9. Mole weight: 496.50. |  |
| Chrysomycin B (Chrysomycin M, Virenomycin M) | Antibiotic. Topoisomerase II inhibitor. Mediates a unique cross-linking reaction between DNA and histidine H3. Anti-neoplastic. Photosensitizing compound. Antitumor compound against human cell lines. Less potent than chrysomycin A. Group: Biochemicals. Grades: Highly Purified. CAS No. 83852-56-6. Pack Sizes: 250ug, 1mg. US Biological Life Sciences. |  Worldwide |
| Chrysomycin B (Chrysomycin M, Virenomycin M, Albacarcin M) | Chrysomycin B is a minor analogue in a complex of C-glycoside antitumor actives isolated from Streptomyces. Chrysomycin B, containing a methyl group in the 8-position, is less active than its vinyl analogue (Chrysomycin A), albeit still a potent antitumor active and an inhibitor of the catalytic activity of human topoisomerase II. More recent research on related metabolites, the gilvocarcins, suggests that chrysomycins may act as photoactivated crosslinkers of DNA to histones. Group: Biochemicals. Alternative Names: Chrysomycin M, Virenomycin M, Albacarcin M. Grades: Highly Purified. CAS No. 83852-56-6. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| 4'-Acetylchrysomycin B | 4'-Acetylchrysomycin B is a bacterial metabolite of chrysomycin B which has been found in Streptomyces and it has antibacterial and anticancer activities. It is active against strains of B. subtilis, B. cereus, Corynebacterium bovis, and E. faecalis (MICs = 2-64 μg/ml). 4'-Acetylchrysomycin B is also cytotoxic against a panel of human cancer cell lines, including doxorubicin-sensitive or -resistant cells (IC50s = 1.7-14 and 260-370 ng/ml, respectively). Synonyms: 4'-acetylchrysomycin B; Acetylchrysomycin A, 4'-; PD143424. Grades: >95% by HPLC. Molecular formula: C29H30O10. Mole weight: 538.54. | |
| Chrysomycin A (Chrysomycin V, Virenomycin V, Albacarcin V) | Chrysomycin A is the major analogue in a complex of C-glycoside antitumor actives isolated from Streptomyces. Chrysomycin A, with a vinyl group in the 8-position, is the most potent analogue of the complex, which is thought to act as an inhibitor of the catalytic activity of human topoisomerase II. Chrysomyin A has a potent antibacterial, antifungal, antiviral and antitumor profile. More recent research on related metabolites, the gilvocarcins, suggests that chrysomycins may act as photoactivated, crosslinkers of DNA to histones. Group: Biochemicals. Alternative Names: Chrysomycin V, Virenomycin V, Albacarcin V. Grades: Highly Purified. CAS No. 82196-88-1. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| 4'-Acetylchrysomycin C | 4'-Acetyl chrysomycin C is a bacterial metabolite originally isolated from Streptomyces. Grades: >95% by HPLC. Molecular formula: C30H32O10. Mole weight: 552.57. | |
| Chrysomycin a | Chrysomycin A (Chr-A), an antibiotic, can be obtained from Streptomyces. Chrysomycin A exhibits antitumor and anti-tuberculous and MRSA activities. As for glioblastoma, Chrysomycin A inhibits the proliferation, migration, and invasion of cancer cells through the Akt/GSK-3β/β-catenin signaling pathway. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Albacarcin V, MLS002701849, NSC354844, 1,5-anhydro-6-deoxy-1-(8-ethenyl-1-hydroxy-10,12-dimethoxy-6-oxo-6h-dibenzo[c,h]chromen-4-yl)-3-c-methylhexitol, 82196-88-1, VIRENOMYCIN V, AC1Q6MMD, AC1L3VB3, KST-1B9536, AR-1B8017, NSC613946, NSC 354844, NSC-354844, NSC-613946, NCI60_003193, SMR001565441, 4-(6-Deoxy-3-C-methyl-.beta.-gulopyranosyl)-8-vinyl-1-hydroxy-10,12-dimethoxy-6H-benzo[d]naphtho[1,2-b]. Product Category: Inhibitors. CAS No. 82196-88-1. Molecular formula: C28H28O9. Mole weight: 508.52. Purity: 0.96. IUPACName: 8-ethenyl-1-hydroxy-10,12-dimethoxy-4-(3,4,5-trihydroxy-4,6-dimethyloxan-2-yl)naphtho[1,2-c]isochromen-6-one. Canonical SMILES: CC1C(C(C(C(O1)C2=C3C(=C(C=C2)O)C(=CC4=C3OC(=O)C5=CC(=CC(=C54)OC)C=C)OC)O)(C)O)O. Density: 1.405g/cm³. Product ID: ACM82196881. Alfa Chemistry ISO 9001:2015 Certified. Categories: Chrysomyinae. |  |
| Chrysomycin A | Chrysomycin A is a C-glycoside antitumor antibiotic isolated from Streptomyces, and it is an inhibitor of the catalytic activity of human topoisomerase II. It has effective antibacterial, antifungal, antiviral and antitumor activities. It may act as a light-activated cross-linking agent between DNA and histones. Synonyms: Chrysomycin V; Virenomycin V; Albacarcin V. Grades: >99% by HPLC. CAS No. 82196-88-1. Molecular formula: C28H28O9. Mole weight: 508.51. | |
| O-Deacetyl-ravidomycin (Antibiotic AY 26623) | O-deacetyl-ravidomycin is the more active and stable analogue of the ravidomycin complex produced by Streptomyces ravidus. The metabolite shows potent, light dependent antitumour activity. Microbial Screening Technologies in-house bioassays detected weak antibacterial and antifungal activity. O-Deacetyl-ravidomycin, like the related gilvocarcins and chrysomycins, is thought to act as a topoisomerase II inhibitor. Group: Biochemicals. Alternative Names: Antibiotic AY 26623. Grades: Highly Purified. CAS No. 88580-27-2. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Chrysomycin A (Chrysomycin V, Virenomycin V) | Antibiotic. Topoisomerase II inhibitor. Mediates a unique cross-linking reaction between DNA and histidine H3. Anti-neoplastic. Photosensitizing compound. Antitumor compound against human cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 82196-88-1. Pack Sizes: 250ug, 1mg. US Biological Life Sciences. | Worldwide |
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