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Cidofovir (GS 0504) is an acyclic monophosphate nucleotide analogue and CMV inhibitor with antiviral activity. Cidofovir inhibits cytomegalovirus (CMV) replication by selectively inhibiting viral DNA polymerase. Cidofovir induces apoptosis and can be used in studies of AIDS cytomegalovirus retinitis, herpes, and cancer [1] [3]. Cidofovir also has anti- orthopoxvirus and anti-variola activities [4]. Uses: Scientific research. Group: Natural products. Alternative Names: GS 0504; HPMPC; (S)-HPMPC. CAS No. 113852-37-2. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17438.
Cidofovir
Cidofovir is inhibitory to CMV plaque formation even when added to the cells at 48 hr post infection with IC50 of 0.9 μg/mL for Davis and 1.6 μg/mL for AD-169 strains,respectively. Synonyms: Vistide; HPMPC; (S)-HPMPC; Cidofovir anhydrous; GS-504; GS 504; GS504; (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine; (S)-(((1-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl)oxy)methyl)phosphonic acid. Grades: ≥98% by HPLC. CAS No. 113852-37-2. Molecular formula: C8H14N3O6P. Mole weight: 279.19.
Cidofovir, anhydrous
Cidofovir, anhydrous. Group: Biochemicals. Grades: Highly Purified. CAS No. 113852-37-2. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C8H14N3O6P. US Biological Life Sciences.
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Cidofovir Diphosphate
Cidofovir Diphosphate - a powerful antiviral agent - is essential in combating cytomegalovirus (CMV) retinitis in AIDS patients. This innovative compound can also effectively treat other herpesvirus infections, including herpes simplex virus (HSV) and varicella-zoster virus (VZV). Its mechanism of action involves the inhibition of viral DNA synthesis and the suppression of viral particle replication, mitigating the continued spread of the virus. Synonyms: (S)-1-(3-Hydroxy-2-phosphonylmethoxyproypl)Cytosine-Diphosphate. Grades: ≥90% by AX-HPLC. Molecular formula: C8H16N3O12P3. Mole weight: 439.10.
Cidofovir Diphosphate Trisodium Salt
Cidofovir Diphosphate Trisodium Salt has antiviral activity, which is used against herpes viruses. Cidofovir Diphosphate is a metabolite in human cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 352525-57-6. Pack Sizes: 500ug, 1mg. Molecular Formula: C8H13N3Na3O12P3, Molecular Weight: 505.09. US Biological Life Sciences.
Worldwide
Cidofovir Hydrate
An injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis in patients with AIDS. It suppresses CMV replication by selective inhibition of viral DNA polymerase and therefore prevention of viral replication and transcription. It is used in the treatment of acyclovir resistant herpes as well as a complementary intralesional therapy against papillomatosis caused by human papillomavirus (HPV). Group: Biochemicals. Alternative Names: [ [ (1S) -2- (4-Amino-2-oxo-1 (2H) -pyrimidinyl) -1- (hydroxymethyl) ethoxy] methyl] phosphonic Acid Hydrate; 1-[ (S) -3-Hydroxy-2- (phosphonomethoxy) propyl]cytosine Hydrate; (S) - [ [2- (4-Amino-2-oxo-1 (2H) -pyrimidinyl) -1- (hydroxymethyl) ethoxy] methyl] phosphonic Acid Hydrate; (S) -1- (3-hydroxy-2-phosphonomethoxypropyl ) cytosine Hydrate; (S)-HPMPC Hydrate; Cidovir Hydrate; GS 0504 Hydrate; Vistide Hydrate. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Brincidofovir (CMX001), the lipid-conjugated prodrug of Cidofovir (HY-17438), is an orally available, long-acting antiviral. Brincidofovir shows activity against a broad spectrum of DNA viruses including cytomegalovirus (CMV), adenovirus (ADV), varicella zoster virus, herpes simplex virus, polyomaviruses, papillomaviruses, poxviruses, and mixed double-stranded DNA virus infections. Brincidofovir, an oral antiviral in late stage development, has proven effective against orthopoxviruses in vitro and in vivo. [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CMX001; HDP-CDV. CAS No. 444805-28-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14532.
CMX 001
CMX 001 is an antiviral inhibitor, working against BK polymavirus replication in primary human urothelial cells.An alkoxyalkyl ester prodrug containing the synthetic, acyclic nucleoside monophosphate analog cidofovir linked, through its phosphonate group, to a lipid, 3-hexadecyloxy-1-propanol, with antiviral activity against double-stranded DNA viruses. Uses: Broad spectrum antiviral drug. Synonyms: CMX 001; CMX-001; CMX001; HDP-CDV; HDPCDV; Brincidofovir; [(2S)-1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]oxymethyl-(3-hexadecoxypropoxy)phosphinic acid. Grades: ≥98%. CAS No. 444805-28-1. Molecular formula: C27H52N3O7P. Mole weight: 561.70.
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