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Clavulanic acid is a naturally occurring powerful bacterial β-lactamases inhibitor for research of infections caused by bacteria, including infections of the ears. Clavulanic acid is active against a wide spectrum of gram-positive and gram-negative bacterias [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 58001-44-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0256.
Clavulanic acid
It is produced by the strain of Streptomyces clavuligerus. Clavulanic acid has a strong inhibition of β-lactamase activity, almost no antibacterial effect. Synonyms: Acido clavulanico; Acide clavulanique; acidum clavulanicum; Clavulansaeure. Grades: 95%. CAS No. 58001-44-8. Molecular formula: C8H9NO5. Mole weight: 199.16.
Clavulanic acid dimer impurity
Clavulanic acid dimer impurity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Clavulanic Acid DiMer IMpurity;(2R,4R,5Z)-4-Carboxy-5-(2-hydroxyethylidene)-3-[[(2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]hept-2-yl]carbonyl]-2-oxazolidineacetic Acid;PotassiuM Clavunate IMpurity E. Product Category: Heterocyclic Organic Compound. CAS No. 1260617-10-4. Molecular formula: C16H18N2O10. Mole weight: 398.32152. Product ID: ACM1260617104. Alfa Chemistry ISO 9001:2015 Certified.
Clavulanic Acid Methyl Ester
Clavulanic Acid Methyl Ester is a substituted Clavulanic acid as β-lactamase inhibitor. Group: Biochemicals. Alternative Names: (2R, 3Z, 5R)-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3. 2. 0]heptane-2-carboxylic Acid Methyl Ester; [2R-(2α, 3Z, 5α)]- 3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3. 2. 0]heptane-2-carboxylic Acid Methyl Ester; Methyl Clavulanate. Grades: Highly Purified. CAS No. 57943-82-5. Pack Sizes: 5mg. US Biological Life Sciences.
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Clavulanic acid methyl ester-d3
Clavulanic acid methyl ester-d3. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. US Biological Life Sciences.
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Clavulanic Acid Potassium Salt in Cellulose (1:1 mixture)
Clavulanic Acid is a β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness. Group: Biochemicals. Alternative Names: Potassium Clavulanate in Cellulose. Grades: Highly Purified. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
Clavulanic Acid, Potassium Salt (MM 14151, Potassium Clavulanate)
Clavulanic acid is a beta-lactam antibiotic produced by several species of the genus Streptomyces. The free acid degrades and is isolated and maintained as either the sodium or potassium salt. Clavulanate is a weak antibiotic but is a potent inhibitor of beta- lactamases. In combination with penicillin and cephalosporins it shows potent synergistic activity. Clavulanic acid is a suicide inhibitor, covalently binding to a serine residue in the active site of the beta-lactamase. Group: Biochemicals. Alternative Names: Timentin; Ticarcillin; MM 14151; [2R-(2α, 3Z, 5α)]-3-(2-hydroxyethylidene)-7-oxo-4-oxa- 1-azabicyclo[3. 2. 0]heptane-2-carboxylate potassium salt. Grades: Highly Purified. CAS No. 61177-45-5. Pack Sizes: 10mg, 50mg, 100mg, 1g. US Biological Life Sciences.
Worldwide
Clavulanic acid potassium salt (Potassium Clavulanate)/Avicel (1:1)
1g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C8H8KNO5. CAS No. 61177-45-5. Prepack ID 87644048-1g. Molecular Weight 237.25. See USA prepack pricing.
4-[4-(2-Hydroxyethyl)-1H-pyrrole-3-carbonyloxymethyl]-1H-pyrrole-3-carboxylic acid (clavulanic acid impurity). Group: Biochemicals. Alternative Names: Potassium clavunate impurity F. Grades: Highly Purified. CAS No. 1260857-16-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C13H14N2O5. US Biological Life Sciences.
Worldwide
1-Amino-4-hydroxy-2-butanone hydrochloride
It is a metabolite of Clavulanic Acid. Synonyms: 2-Butanone, 1-amino-4-hydroxy-, hydrochloride. Grades: 95%. CAS No. 92632-79-6. Molecular formula: C4H10ClNO2. Mole weight: 139.58.
1-Amino-4-hydroxy-2-butanone Hydrochloride
1-Amino-4-hydroxy-2-butanone is a metabolite of Clavulanic Acid (C563750, potassium salt) which is a β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness. Group: Biochemicals. Grades: Highly Purified. CAS No. 92632-79-6. Pack Sizes: 25mg, 250mg. Molecular Formula: C4H10ClNO2, Molecular Weight: 139.58. US Biological Life Sciences.
Worldwide
1-Azido-4-hydroxy-2-butanone
1-Azido-4-hydroxy-2-butanone is an intermediate in the synthesis of 3-Ethyl-2,5-pyrazinediethanol (E925605), an impurity of Clavulanic Acid (C563750), an degradation product that decrease glycerol consumption and oxygen uptake rates in cultures of Streptomyces clavuligerus. Group: Biochemicals. Grades: Highly Purified. CAS No. 1824421-22-8. Pack Sizes: 500mg, 1g. Molecular Formula: C4H7N3O2. US Biological Life Sciences.
Worldwide
1-Bromo-4-hydroxy-2-butanone (>90%)
1-Bromo-4-hydroxy-2-butanone Is an intermediate in the synthesis of 3-Ethyl-2,5-pyrazinediethanol (E925605), an impurity of Clavulanic Acid (C563750), an degradation product that decrease glycerol consumption and oxygen uptake rates in cultures of Streptomyces clavuligerus. Group: Biochemicals. Grades: Highly Purified. CAS No. 1138728-96-7. Pack Sizes: 10mg, 100mg. Molecular Formula: C4H7BrO2. US Biological Life Sciences.
2- (2- ( (t-Butyldimethylsilyl) methoxy) ethyl) -5- (2- ( (tert-butyldimethylsilyl) oxy) ethyl) pyrazine is an intermediate in synthesizing 3-Methyl-2,5-bis-(2-hydroxyethyl)pyrazine (M295340), which is a degradation product of Clavulanic Acid (C563750), a β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C20H40N2O2Si2. US Biological Life Sciences.
2- (2- ( (t-Butyldimethylsilyl) methoxy) ethyl) -5- (2- ( (tert-butyldimethylsilyl) oxy) ethyl) pyrazine N-Oxide is an intermediate in synthesizing 3-Methyl-2,5-bis-(2-hydroxyethyl)pyrazine (M295340), which is a degradation product of Clavulanic Acid (C563750), a β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C21H42N2O3Si2. US Biological Life Sciences.
Worldwide
2,5-Bis(2-(benzyloxy)ethyl)-3-methylpyrazine
2,5-Bis(2-(benzyloxy)ethyl)-3-methylpyrazine is an intermediate in synthesizing 3-Methyl-2,5-bis-(2-hydroxyethyl)pyrazine (M295340), which is a degradation product of Clavulanic Acid (C563750), a β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C23H26N2O2. US Biological Life Sciences.
Worldwide
2, 5-Bis (2- (benzyloxy) ethyl) pyrazine
2, 5-Bis (2- (benzyloxy) ethyl) pyrazine is an intermediate in synthesizing 3-Methyl-2,5-bis-(2-hydroxyethyl)pyrazine (M295340), which is a degradation product of Clavulanic Acid (C563750), a β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C22H24N2O2. US Biological Life Sciences.
Worldwide
2, 5-Bis (2- (benzyloxy) ethyl) pyrazine N-Oxide
2, 5-Bis (2- (benzyloxy) ethyl) pyrazine N-Oxide is an intermediate in synthesizing 3-Methyl-2,5-bis-(2-hydroxyethyl)pyrazine (M295340), which is a degradation product of Clavulanic Acid (C563750), a β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C22H24N2O3. US Biological Life Sciences.
Worldwide
2,5-Dimethylpyrazine
2,5-Dimethylpyrazine is used as a reagent in the synthesis of bone-targeted proteasome inhibitors for multiple myeloma (MM). 2,5-Dimethylpyrazine is also used in the preparation of 3-Methyl-2,5-bis-(2-hydroxyethyl)pyrazine (M295340); a degredation product of Clavulanic Acid (C563750) which is a β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness. Group: Biochemicals. Grades: Highly Purified. CAS No. 123-32-0. Pack Sizes: 5g, 25g. Molecular Formula: C6H8N2. US Biological Life Sciences.
(2R,5R,Z)-Benzyl 3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3. 2. 0]heptane-2-carboxylate is an intermediate in the synthesis of Clavulanic Acid Potassium Salt-d4 which is the isotope labelled analog of Clavulanic Acid Potassium Salt (C563750); a β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness. Group: Biochemicals. Grades: Highly Purified. CAS No. 57943-84-7. Pack Sizes: 5mg, 10mg. Molecular Formula: C15H15NO5. US Biological Life Sciences.
4-(2-(Benzyloxy)ethyl)-1H-pyrrole-3-carboxylic Acid Methyl Ester is an protected intermediate in the synthesis of Clavulanic Acid (C563750), an β-lactamase inhibitor that is added to amoxicillin (A634235) to increase its effectiveness. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
4-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethyl)-1H-pyrrole-3-carboxylic Acid Methyl Ester is an protected intermediate in the synthesis of Clavulanic Acid (C563750), an β-lactamase inhibitor that is added to amoxicillin (A634235) to increase its effectiveness. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
4-(Hydroxymethyl)-1H-pyrrole-3-carboxylic Acid Benzyl Ester is an impurity in the synthesis of Clavulanic Acid (C563750), an β-lactamase inhibitor that is added to amoxicillin (A634235) to increase its effectiveness. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
4- ( ( (tert-Butyldimethylsilyl) oxy) methyl) -1H-pyrrole-3-carboxylic Acid Benzyl Ester is an protected intermediate in the synthesis of Clavulanic Acid (C563750), an β-lactamase inhibitor that is added to amoxicillin (A634235) to increase its effectiveness. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Amoxicillin Clavulanate
A broad-spectrum beta-lactam antibiotic. It is similar in structure to Ampicillin. Synonyms: Amoxicillin and clavulanic acid; Amoksiclav; Amoxyclav; Amoxicillin clavulanate acid; Amoxicillin mixture with Clavulanate; 4-Oxa-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, (2R,3Z,5R)-, mixt. with (2S,5R,6R)-6-(((2R)-amino(4-hydroxyphenyl)acetyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid. Grades: Amoxicillin: ≥54.0%; Clavulanic Acid: ≥26.8%. CAS No. 79198-29-1. Molecular formula: C24H28N4O10S. Mole weight: 564.56.
Augpenin
Augpenin (Ticarcillin-clavulanic acid mixt.) is a mixture of Ticarcillin (HY-139805) and Clavulanic acid (HY-A0256) in a ratio of 15:1 [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Ticarcillin-clavulanic acid mixt. CAS No. 86482-18-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-156264.
Clavulanate Lithium
A beta-lactamase inhibitor. It can irreversibly inactivate beta-lactamase enzymes of beta-lactam resistant microbes preventing them from breaking down beta-lactam antibiotics. Synonyms: (2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate Lithium; Clavulanic acid, lithium salt. Grades: ≥98%. CAS No. 61177-44-4. Molecular formula: C8H8LiNO5. Mole weight: 205.09.
Clavulanate Potassium, Streptomyces sp.
Clavulanic acid is a beta-lactam antibiotic produced by several species of the genus Streptomyces. The free acid degrades and is isolated and maintained as either the sodium or potassium salt. Clavulanate is a weak antibiotic but is a potent inhibitor of beta- lactamases. In combination with penicillin and cephalosporins it shows potent synergistic activity. Clavulanic acid is a suicide inhibitor, covalently binding to a serine residue in the active site of the beta-lactamase. Group: Biochemicals. Alternative Names: Timentin; Ticarcillin; MM 14151; [2R-(2α, 3Z, 5α)]-3-(2-hydroxyethylidene)-7-oxo-4-oxa- 1-azabicyclo[3. 2. 0]heptane-2-carboxylate potassium salt. Grades: Highly Purified. CAS No. 61177-45-5. Pack Sizes: 5mg. US Biological Life Sciences.
(E) -4- ( (tert-Butyldimethylsilyl) oxy) but-2-enoic Acid Benzyl Ester is an protected intermediate in the synthesis of Clavulanic Acid (C563750), an β-lactamase inhibitor that is added to amoxicillin (A634235) to increase its effectiveness. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
N-Succinyl-L-tyrosine
N-Succinyl-L-tyrosine. Group: Biochemicals. Alternative Names: N-(3-Carboxy-1-oxopropyl)-L-tyrosine; Clavulanic acid impurity G. Grades: Highly Purified. CAS No. 374816-32-7. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C13H15NO6. US Biological Life Sciences.
Worldwide
Potassium clavulanate, 1:1 mixture with cellulose
Clavulanic acid is a beta-lactam antibiotic produced by several species of the genus Streptomyces. The free acid degrades and is isolated and maintained as either the sodium or potassium salt. Clavulanate is a weak antibiotic but is a potent inhibitor of beta- lactamases. In combination with penicillin and cephalosporins it shows potent synergistic activity. Clavulanic acid is a suicide inhibitor, covalently binding to a serine residue in the active site of the beta-lactamase. Group: Biochemicals. Alternative Names: Timentin; Ticarcillin; MM 14151; [2R-(2α, 3Z, 5α)]-3-(2-hydroxyethylidene)-7-oxo-4-oxa- 1-azabicyclo[3. 2. 0]heptane-2-carboxylate potassium salt. Grades: Highly Purified. CAS No. 61177-45-5. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C8H8NO5·K. US Biological Life Sciences.
Worldwide
Potassium clavulanate, 1:1 mixture with silicon dioxide
Clavulanic acid is a beta-lactam antibiotic produced by several species of the genus Streptomyces. The free acid degrades and is isolated and maintained as either the sodium or potassium salt. Clavulanate is a weak antibiotic but is a potent inhibitor of beta- lactamases. In combination with penicillin and cephalosporins it shows potent synergistic activity. Clavulanic acid is a suicide inhibitor, covalently binding to a serine residue in the active site of the beta-lactamase. Group: Biochemicals. Alternative Names: Timentin; Ticarcillin; MM 14151; [2R-(2α, 3Z, 5α)]-3-(2-hydroxyethylidene)-7-oxo-4-oxa- 1-azabicyclo[3. 2. 0]heptane-2-carboxylate potassium salt. Grades: Highly Purified. CAS No. 61177-45-5. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C8H8NO5·K. US Biological Life Sciences.
Timentin is a suitable antibiotic for Agrobacterium counterselection and a mixture of two antibiotics: ticarcillin and clavulanic acid. Most wild Agrobacterium isolates have beta-lactamase activity which clavulanic acid exhibits activity towards. Many Agrobacterium isolates are highly susceptible to Timentin. Agrobacterium strains carrying the standard pBR beta-lactamase gene are also Timentin (clavulanic acid) susceptible. Timentin killing of Agrobacterium wild-type strains is three logs greater than with comparable doses of carbenicillin. In plant transformation experiments, 0.1mg/ml Timentin (15:1) is sufficient to counterselect Agrobacterium.The appropriate dose in tissue culture medium is 0.1 mg/ml (not 0.1 mg/liter) of 15:1 mixture or 0.2 mg/ml of 30:1 mixture. To improve efficacy (of any antimicrobial), solid media are best slightly dried before use. At these concentrations, Timentin exhibits no phytotoxicity toArabidopsis root cultures.Ticarcillin Disodium/Potassium Clavulanate =15:1. Group: Biochemicals. Alternative Names: Timentin; Ticarcillin; MM 14151; [2R-(2α, 3Z, 5α)]-3-(2-hydroxyethylidene)-7-oxo-4-oxa- 1-azabicyclo[3. 2. 0]heptane-2-carboxylate disodium/potassium salt. Grades: Highly Purified. CAS No. 4697-14-7,61177-45-5. Pack Sizes: 1g, 10g, 25g. US Biological Life Sciences.
Worldwide
Trimethyl Bromoorthoacetate
Trimethyl Bromoorthoacetate is an intermediate in the synthesis of 3,6-Bis(2-hydroxyethyl)-2-pyrazinepropanoic Acid (B444100), an impurity of Clavulanic Acid (C563750). Group: Biochemicals. Alternative Names: Bromoorthoacetic Acid Trimethyl Ester; 2-Bromo-1,1,1-trimethoxyethane. Grades: Highly Purified. CAS No. 40070-40-4. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
clavaminate synthase
Contains nonheme iron. Catalyses three separate oxidative reactions in the pathway for the biosythesis of the β-lactamase inhibitor clavulanate in Streptomyces clavuligerus. The first step (hydroxylation) is separated from the latter two (oxidative cyclization and desaturation) by the action of EC 3.5.3.22, proclavaminate amidinohydrolase. The three reactions are all catalysed at the same nonheme iron site. Group: Enzymes. Synonyms: clavaminate synthase 2; clavaminic acid synthase. Enzyme Commission Number: EC 1.14.11.21. CAS No. 122799-56-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0638; clavaminate synthase; EC 1.14.11.21; 122799-56-8; clavaminate synthase 2; clavaminic acid synthase. Cat No: EXWM-0638.
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