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Clazosentan Clazosentan, also called as AXV 034, Ro 61-1790 or VML 588, a novel endothelin A antagonist, improves cerebral blood flow and behavior after traumatic brain injury. In 2016 Actelion plans two phase III trials of Clazosentan for Cerebral vasospasm (in patients with aneurysmal subarachnoid haemorrhage) in Japan. Synonyms: N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)pyridin-4-yl]pyrimidin-4-yl]-5-methylpyridine-2-sulfonamideAXV034; AXV-034; AXV 034; AXV 034343; AXV-034343; AXV-343434; Ro 61-1790; Ro-61-1790; VML 588; VML-588; VML 588; Clazosentan. Grades: 95%. CAS No. 180384-56-9. Molecular formula: C25H23N9O6S. Mole weight: 577.57. BOC Sciences 10
Clazosentan Clazosentan (Ro 61-1790) is a selective endothelin A (ET A ) receptor antagonist. Clazosentan inhibits ET-1-mediated vasoconstriction. Clazosentan prevents cerebral vasospasm, vasospasm-related cerebral infarction [1] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 61-1790; VML 588; AXV-034343. CAS No. 180384-56-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17352. MedChemExpress MCE

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