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| Product | Description | |
|---|---|---|
| Clodronate | Clodronate binds to calcium and inhibits osteoclastic bone resorption and hydroxyapatite crystal formation and dissolution, resulting in a reduction of bone turnover. This agent may control malignancy-associated hypercalcemia, inhibit osteolytic bone metastasis and decrease pain. Uses: Bone density conservation agents. Synonyms: Clodronic Acid; Acido clodronico; Dichloromethylidene diphosphonate; dichloromethylene-1,1-diphosphonic acid; Dichlormethylen-bis(phosphonsaeure). Grade: >98%. CAS No. 10596-23-3. Molecular formula: CH4Cl2O6P2. Mole weight: 244.89. |  |
| Clodronate Disodium | Clodronic acid (INN) or clodronate disodium (USAN) is a first generation (non-nitrogenous) bisphosphonate. It is an anti-osteoporotic drug approved for the prevention and treatment of osteoporosis in post-menopausal women and men to reduce vertebral fractures, hyperparathyroidism, hypercalcemia in malignancy, multiple myeloma and fracture related pain because of its potent anti-inflammatory and analgesic effects shown as a reduction in inflammatory markers like IL-1β, IL-6, and TNF-alfa. Uses: Bone density conservation agents. Synonyms: Disodium clodronate; Clodronic acid disodium salt; Clasteon; Lodronate; Ostac; Bonefos; Clodronate disodium anhydrous. Grade: >98%. CAS No. 22560-50-5. Molecular formula: CH2Cl2Na2O6P2. Mole weight: 288.86. | |
| Clodronate disodium tetrahydrate | Clodronate disodium tetrahydrate (Disodium clodronate tetrahydrate) is first-generation bisphosphonate, with anti-osteoporotic, anti-inflammatory and analgesic effects. Clodronate disodium tetrahydrate is a selective, potent, reversible and Cl- competitive vesicular nucleotide transporter (VNUT) inhibitor, with an IC50 of 15.6 nM. Clodronate disodium tetrahydrate inhibits vesicular ATP release from neurons and reduces chronic neuropathic and inflammatory pain[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Disodium clodronate tetrahydrate. CAS No. 88416-50-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-107794. |  |
| Clodronate disodium tetrahydrate | Clodronate is a non-nitrogenous bisphosphonate that can bind to bone to reduce the bone resorption. It is used as an anti-osteoporotic drug for the prevention of osteoporosis in post-menopausal women and men. Uses: The treatment of osteoporosis. Synonyms: (Dichloromethylene)bisphosphonic Acid Disodium Salt Tetrahydrate; Sodium clodronate hydrate; Disodium [dichloro(phosphonato)methyl]phosphonic acid tetrahydrate. Grade: >98%. CAS No. 88416-50-6. Molecular formula: CH10Cl2Na2O10P2. Mole weight: 360.908. | |
| Clodronate Liposome | Clodronate Liposome is a multilamellar liposome suspension in which clodronate is encapsulated in the aqueous compartments of the liposomes. When animals or cells are treated with Clodronate Liposome, phagocytic cells recognize the liposomes as invading foreign particles and proceed to remove the liposomes from the local tissue or serum via phagocytosis. The liposomes then release clodronate into the cytosol, resulting in cell death. Non-encapsulated clodronate cannot cross the cell membrane to initiate cell death. Group: Clodronate liposome. |  |
| Clipos Anionic Clodronate Encapsulated Liposomes | CD Bioparticles provides CliposTM Anionic Clodronate Encapsulated Liposomes, Liposomal Clodronate with a lipid composition of PC/PG/Cholesterol for drug delivery. Group: Liposomal clodronate. |  |
| Clipos Clodronate Encapsulated Liposomes | CD Bioparticles provides Clipos Clodronate Encapsulated Liposomes, Liposomal Clodronate with a lipid composition of L-α-PC/Cholesterol (70/30 molar ratio) for drug delivery. Group: Liposomal clodronate. | |
| Clodronic Acid, Disodium Salt, Tetrahydrate (Clodronate Disodium, Bonefos, Clasteon, Clastoban) | A biphosphonate bone resorption inhibitor. Group: Biochemicals. Alternative Names: Clodronate Disodium, Bonefos, Clasteon, Clastoban. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. |  Worldwide |
| Creative Biolabs | A leading biotechnology company specializing in advanced lipid-based delivery systems. Committed to advancing drug delivery technologies, the company offers a comprehensive range of products, including phospholipids, lipids, cationic liposomes, clodronate liposomes, drug-loaded liposomes, and liposome preparation kits. featured listing | |
| Clodronic acid | Clodronic acid is an orally active bisphosphonate, which is used for researching osteoporosis and diseases associated with excessive bone resorption. Clodronic acid inhibits bone resorption through induction of osteoclast apoptosis. Clodronic acid is effective in the maintenance or improvement of bone mineral density [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Clodronate. CAS No. 10596-23-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0657. | |
| Clodronic acid, disodium salt, hydrate | Clodronic acid, disodium salt, hydrate. Group: Biochemicals. Alternative Names: (Dichloromethylene) bisphosphonic acid disodium salt tetrahydrate; Clodronate disodium; Bonefos. Grades: Highly Purified. CAS No. 22560-50-5. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: CH2Cl2Na2O6P2. US Biological Life Sciences. | Worldwide |
| Control Liposome | Control Liposome are recognized and phagocytosed by the same mechanism as Clodronate Liposome, which do not contain clodronate, thus the phagocytic cells are not killed. However, phagocytes do respond to the ingestion of control liposomes by cytokine secretion, temporary suspension of phagocytic activity and other responses. Group: Clodronate liposome. | |
| Clodronic acid | Clodronic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CLODRONIC ACID;Disodium diphosphonate;Clodronic;(Dichloromethylene)bis(phosphonic acid);ARC-69931;Dichloromethylenebis(phosphonic acid);Dichloromethylenebisphosphonic acid;Aids071014. CAS No. 10596-23-3. Molecular formula: CH4Cl2O6P2. Mole weight: 244.89. Purity: 0.97. IUPACName: [dichloro(phosphono)methyl]phosphonicacid. Canonical SMILES: C(P(=O)(O)O)(P(=O)(O)O)(Cl)Cl. Density: 2.306g/cm³. ECNumber: 234-212-1. Product ID: ACM10596233. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Clodronic Acid Monoisopropyl Ester | Clodronic Acid Monoisopropyl Ester. Group: Biochemicals. Alternative Names: [Dichloro [hydroxy (1-methylethoxy) phosphinyl] methyl] phosphonic Acid. Grades: Highly Purified. CAS No. 134757-52-1. Pack Sizes: 10mg. Molecular Formula: C4H10Cl2O6P2, Molecular Weight: 286.97. US Biological Life Sciences. | Worldwide |
| Tetraisopropyl Dichloromethylene Diphosphonate | An intermediate in the sythesis of Clodronic Acid, Disodium Salt, Tetrahydrate, a biphosphonate bone resorption inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
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