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| Product | Description | |
|---|---|---|
| Clodronate | Clodronate binds to calcium and inhibits osteoclastic bone resorption and hydroxyapatite crystal formation and dissolution, resulting in a reduction of bone turnover. This agent may control malignancy-associated hypercalcemia, inhibit osteolytic bone metastasis and decrease pain. Uses: Bone density conservation agents. Synonyms: Clodronic Acid; Acido clodronico; Dichloromethylidene diphosphonate; dichloromethylene-1,1-diphosphonic acid; Dichlormethylen-bis(phosphonsaeure). Grades: >98%. CAS No. 10596-23-3. Molecular formula: CH4Cl2O6P2. Mole weight: 244.89. |  |
| Clodronate Disodium | Clodronic acid (INN) or clodronate disodium (USAN) is a first generation (non-nitrogenous) bisphosphonate. It is an anti-osteoporotic drug approved for the prevention and treatment of osteoporosis in post-menopausal women and men to reduce vertebral fractures, hyperparathyroidism, hypercalcemia in malignancy, multiple myeloma and fracture related pain because of its potent anti-inflammatory and analgesic effects shown as a reduction in inflammatory markers like IL-1β, IL-6, and TNF-alfa. Uses: Bone density conservation agents. Synonyms: Disodium clodronate; Clodronic acid disodium salt; Clasteon; Lodronate; Ostac; Bonefos; Clodronate disodium anhydrous. Grades: >98%. CAS No. 22560-50-5. Molecular formula: CH2Cl2Na2O6P2. Mole weight: 288.86. | |
| Clodronate disodium tetrahydrate | Clodronate is a non-nitrogenous bisphosphonate that can bind to bone to reduce the bone resorption. It is used as an anti-osteoporotic drug for the prevention of osteoporosis in post-menopausal women and men. Uses: The treatment of osteoporosis. Synonyms: (Dichloromethylene)bisphosphonic Acid Disodium Salt Tetrahydrate; Sodium clodronate hydrate; Disodium [dichloro (phosphonato)methyl]phosphonic acid tetrahydrate. Grades: >98%. CAS No. 88416-50-6. Molecular formula: CH10Cl2Na2O10P2. Mole weight: 360.908. | |
| Clodronate Liposome | Clodronate Liposome is a multilamellar liposome suspension in which clodronate is encapsulated in the aqueous compartments of the liposomes. When animals or cells are treated with Clodronate Liposome, phagocytic cells recognize the liposomes as invading foreign particles and proceed to remove the liposomes from the local tissue or serum via phagocytosis. The liposomes then release clodronate into the cytosol, resulting in cell death. Non-encapsulated clodronate cannot cross the cell membrane to initiate cell death. Group: Clodronate liposome. Categories: Niosomes, ethosomes, and transfersomes. |  |
| Clodronate Liposome (Anionic) | Clodronate Liposomes (Anionic) is a liposome suspension in which clodronate is encapsulated in the aqueous compartments of the anionic liposomes. When animals or cells are treated with Clodronate Liposome, phagocytic cells recognize the liposomes as invading foreign particles and proceed to remove the liposomes from the local tissue or serum via phagocytosis. The liposomes then release clodronate into the cytosol, resulting in cell death. Non-encapsulated clodronate cannot cross the cell membrane to initiate cell death. Group: Clodronate liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| Clodronic Acid, Disodium Salt, Tetrahydrate (Clodronate Disodium, Bonefos, Clasteon, Clastoban) | A biphosphonate bone resorption inhibitor. Group: Biochemicals. Alternative Names: Clodronate Disodium, Bonefos, Clasteon, Clastoban. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. |  Worldwide |
| Control Clodronate Liposome (Anionic) | Control Clodronate Liposomes (Anionic) are recognized and phagocytosed by the same mechanism as Clodronate Liposomes (Anionic), which do not contain clodronate, thus the phagocytic cells are not killed. It can serve as a negative control for Clodronate Lipomes (Anionic) in macroscopic depletion studies. Group: Clodronate liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| Control High Potency Clodronate Liposome (Anionic) | The Control High Potency Clodronate Liposomes (Anionic) are recognized and phagocytosed by the same mechanism as High Potency Clodronate Liposomes (Anionic), which do not contain clodronate, thus the phagocytic cells are not killed. It can serve as a negative control for High Potency Clodronate Liposomes (Anionic) in macroscopic depletion studies. Group: Clodronate liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| Control High Potency Clodronate Liposome (Neutral) | The Control High Potency Clodronate Liposome (Neutral) are recognized and phagocytosed by the same mechanism as High Potency Clodronate Liposome (Neutral), which do not contain clodronate, thus the phagocytic cells are not killed. It can serve as a negative control for High Potency Clodronate Liposome (Neutral) in macroscopic depletion studies. Group: Clodronate liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes. | |
| DiA Labeled Control Clodronate Liposome (Anionic) | The DiA Labeled Control Clodronate Liposomes (Anionic) contain the lipophilic dye DiA bound within a bilayer. They have comparable physical and chemical properties to Clodronate Liposomes (Anionic), except for the absence of internally encapsulated Clodronate. They are used for tracking the cellular uptake of liposomes. Group: Clodronate liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DiA Labeled Control Clodronate Liposome (Neutral) | The DiA Labeled Control Clodronate Liposome (Neutral) contain the lipophilic dye DiA bound within a bilayer. They have comparable physical and chemical properties to Clodronate Liposome, except for the absence of internally encapsulated Clodronate. They are used for tracking the cellular uptake of liposomes. Group: Clodronate liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DiD Labeled Control Clodronate Liposome (Anionic) | The DiD Labeled Control Clodronate Liposomes (Anionic) contain the lipophilic dye DiD bound within a bilayer. They have comparable physical and chemical properties to Clodronate Liposomes (Anionic), except for the absence of internally encapsulated Clodronate. They are used for tracking the cellular uptake of liposomes. Group: Clodronate liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DiD Labeled Control Clodronate Liposome (Neutral) | The DiD Labeled Control Clodronate Liposome (Neutral) contain the lipophilic dye DiD bound within a bilayer. They have comparable physical and chemical properties to Clodronate Liposome, except for the absence of internally encapsulated Clodronate. They are used for tracking the cellular uptake of liposomes. Group: Clodronate liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DiI Labeled Control Clodronate Liposome (Anionic) | The DiI Labeled Control Clodronate Liposomes (Anionic) contain the lipophilic dye DiI bound within a bilayer. They have comparable physical and chemical properties to Clodronate Liposomes (Anionic), except for the absence of internally encapsulated Clodronate. They are used for tracking the cellular uptake of liposomes. Group: Clodronate liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DiI Labeled Control Clodronate Liposome (Neutral) | The DiI Labeled Control Clodronate Liposome (Neutral) contain the lipophilic dye DiI bound within a bilayer. They have comparable physical and chemical properties to Clodronate Liposome, except for the absence of internally encapsulated Clodronate. They are used for tracking the cellular uptake of liposomes. Group: Clodronate liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DiR Labeled Control Clodronate Liposome (Anionic) | The DiR Labeled Control Clodronate Liposomes (Anionic) contain the lipophilic dye DiR bound within a bilayer. They have comparable physical and chemical properties to Clodronate Liposomes (Anionic), except for the absence of internally encapsulated Clodronate. They are used for tracking the cellular uptake of liposomes. Group: Clodronate liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DiR Labeled Control Clodronate Liposome (Neutral) | The DiR Labeled Control Clodronate Liposome (Neutral) contain the lipophilic dye DiR bound within a bilayer. They have comparable physical and chemical properties to Clodronate Liposome, except for the absence of internally encapsulated Clodronate. They are used for tracking the cellular uptake of liposomes. Group: Clodronate liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| High Potency Clodronate Liposome (Anionic) | The High-Potency Clodronate Liposomes (Anionic) represent a high-concentration formulation of Clodronate Liposomes (Anionic), designed to fulfill the need for administration scenarios where large-volume dosing is impractical. Group: Clodronate liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| High Potency Clodronate Liposome (Neutral) | The High Potency Clodronate Liposome (Neutral) represent a high-concentration formulation of Clodronate Liposome, designed to fulfill the need for administration scenarios where large-volume dosing is impractical. Group: Clodronate liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes. | |
| Mannosylated Clodronate Liposome | Mannosylated Clodronate Liposome is a multilamellar liposome suspension in which clodronate is encapsulated in the aqueous compartments of the mannosylated liposomes. When animals or cells are treated with Mannosylation Clodronate Liposome, phagocytic cells recognize the liposomes as invading foreign particles and proceed to remove the liposomes from the local tissue or serum via phagocytosis. The liposomes then release clodronate into the cytosol resulting in cell death. Non-encapsulated clodronate cannot cross the cell membrane to initiate cell death. Group: Clodronate liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| Creative Biolabs | A leading biotechnology company specializing in advanced lipid-based delivery systems. Committed to advancing drug delivery technologies, the company offers a comprehensive range of products, including phospholipids, lipids, cationic liposomes, clodronate liposomes, drug-loaded liposomes, and liposome preparation kits. featured listing | |
| Clodronic acid | Clodronic acid is an orally active bisphosphonate, which is used for researching osteoporosis and diseases associated with excessive bone resorption. Clodronic acid inhibits bone resorption through induction of osteoclast apoptosis. Clodronic acid is effective in the maintenance or improvement of bone mineral density [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Clodronate. CAS No. 10596-23-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0657. |  |
| Clodronic acid, disodium salt, hydrate | Clodronic acid, disodium salt, hydrate. Group: Biochemicals. Alternative Names: (Dichloromethylene) bisphosphonic acid disodium salt tetrahydrate; Clodronate disodium; Bonefos. Grades: Highly Purified. CAS No. 22560-50-5. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: CH2Cl2Na2O6P2. US Biological Life Sciences. | Worldwide |
| Control Liposome | Control Liposome are recognized and phagocytosed by the same mechanism as Clodronate Liposome, which do not contain clodronate, thus the phagocytic cells are not killed. However, phagocytes do respond to the ingestion of control liposomes by cytokine secretion, temporary suspension of phagocytic activity and other responses. Group: Clodronate liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DiA Labeled Mannosylated Control Liposome (Neutral) | The DiA Labeled Mannosylated Control Liposome (Neutral) contain the lipophilic dye DiA bound within a bilayer. They have comparable physical and chemical properties to Mannosylated Clodronate Liposome, except for the absence of internally encapsulated Clodronate. They are used for tracking the cellular uptake of liposomes. Group: Clodronate liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DiD Labeled Mannosylated Control Liposome (Neutral) | The DiD Labeled Mannosylated Control Liposome (Neutral) contain the lipophilic dye DiD bound within a bilayer. They have comparable physical and chemical properties to Mannosylated Clodronate Liposome, except for the absence of internally encapsulated Clodronate. They are used for tracking the cellular uptake of liposomes. Group: Clodronate liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DiI Labeled Mannosylated Control Liposome (Neutral) | The DiI Labeled Mannosylated Control Liposome (Neutral) contain the lipophilic dye DiI bound within a bilayer. They have comparable physical and chemical properties to Mannosylated Clodronate Liposome, except for the absence of internally encapsulated Clodronate. They are used for tracking the cellular uptake of liposomes. Group: Clodronate liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DiR Labeled Mannosylated Control Liposome (Neutral) | The DiR Labeled Mannosylated Control Liposome (Neutral) contain the lipophilic dye DiR bound within a bilayer. They have comparable physical and chemical properties to Mannosylated Clodronate Liposome, except for the absence of internally encapsulated Clodronate. They are used for tracking the cellular uptake of liposomes. Group: Clodronate liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| Mannosylated Control Liposome | Mannosylated Control Liposome are recognized and phagocytosed by the same mechanism as Mannosylation Clodronate Liposome, which do not contain clodronate, thus the phagocytic cells are not killed. However, phagocytes do respond to the ingestion of control liposomes by cytokine secretion, temporary suspension of phagocytic activity and other responses. Group: Clodronate liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| Clodronic acid | Clodronic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CLODRONIC ACID;Disodium diphosphonate;Clodronic;(Dichloromethylene)bis(phosphonic acid);ARC-69931;Dichloromethylenebis(phosphonic acid);Dichloromethylenebisphosphonic acid;Aids071014. CAS No. 10596-23-3. Molecular formula: CH4Cl2O6P2. Mole weight: 244.89. Purity: 0.97. IUPACName: [dichloro(phosphono)methyl]phosphonicacid. Canonical SMILES: C(P(=O)(O)O)(P(=O)(O)O)(Cl)Cl. Density: 2.306g/cm³. ECNumber: 234-212-1. Product ID: ACM10596233. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Clodronic Acid Monoisopropyl Ester | Clodronic Acid Monoisopropyl Ester. Group: Biochemicals. Alternative Names: [Dichloro [hydroxy (1-methylethoxy) phosphinyl] methyl] phosphonic Acid. Grades: Highly Purified. CAS No. 134757-52-1. Pack Sizes: 10mg. Molecular Formula: C4H10Cl2O6P2, Molecular Weight: 286.97. US Biological Life Sciences. | Worldwide |
| Tetraisopropyl Dichloromethylene Diphosphonate | An intermediate in the sythesis of Clodronic Acid, Disodium Salt, Tetrahydrate, a biphosphonate bone resorption inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
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