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| Product | Description | |
|---|---|---|
| Clozapine | 25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C18H19ClN4. CAS No. 5786-21-0. Prepack ID 66826682-25mg. Molecular Weight 326.82. See USA prepack pricing. |  |
| Clozapine | Clozapine (HF 1854) is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors. Clozapine is a potent antagonist of dopamine D2 with a K i of 75 nM. Clozapine inhibits the muscarinic M1 receptor and serotonin 5HT2A receptor with K i s of 9.5 nM and 4 nM, respectively [1] [2] [3]. Clozapine is also a potent and selective agonist at the muscarinic M4 receptor ( EC 50 =11 nM) [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HF 1854. CAS No. 5786-21-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-14539. |  |
| Clozapine-d4 | Clozapine-d 4 is the deuterium labeled Clozapine. Clozapine is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors[1][2][3][4][5]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: HF 1854-d4. CAS No. 204395-52-8. Pack Sizes: 1 mg. Product ID: HY-14539S2. | |
| Clozapine-d8 (8-Chloro-11-(4-methyl-1-piperazinyl-d8)-5H-dibenzo[b, e][1, 4]diazepine, HF-1854-d8, Liponex-d8) | An antipsychotic.A representative lot was 92% d8, 8% d7. Group: Biochemicals. Alternative Names: 8-Chloro-11-(4-methyl-1-piperazinyl-d8)-5H-dibenzo[b, e][1, 4]diazepine; HF-1854-d8; Liponex-d8. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Clozapine Impurity 6 | Clozapine Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1025951-76-1. Molecular formula: C20H21ClN4O. Mole weight: 368.86. Catalog: APB1025951761. |  |
| Clozapine N-oxide | Clozapine N-oxide is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide can cross the blood-brain barrier [1] [2] [3] [4]. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor ( EC 50 =11 nM) agonist [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 34233-69-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17366. | |
| Clozapine N-oxide dihydrochloride | Clozapine N-oxide dihydrochloride is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide dihydrochloride activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide dihydrochloride can cross the blood-brain barrier [1] [2] [3] [4]. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor ( EC 50 =11 nM) agonist [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2250025-93-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17366A. | |
| Clozapine (Standard) | Clozapine (Standard) is the analytical standard of Clozapine. This product is intended for research and analytical applications. Clozapine (HF 1854) is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors. Clozapine is a potent antagonist of dopamine D2 with a K i of 75 nM. Clozapine inhibits the muscarinic M1 receptor and serotonin 5HT2A receptor with K i s of 9.5 nM and 4 nM, respectively [1] [2] [3]. Clozapine is also a potent and selective agonist at the muscarinic M4 receptor ( EC 50 =11 nM) [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HF 1854 (Standard). CAS No. 5786-21-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14539R. | |
| 9-Hydroxyl Clozapine | 9-Hydroxyl Clozapine. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1239601-19-4. Molecular formula: C18H19ClN4O. Mole weight: 342.83. Catalog: APB1239601194. | |
| Deschloroclozapine | Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist. Deschloroclozapine binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively. [11C]-Deschloroclozapine is developed as a promising PET tracer for DREADD imaging[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1977-7-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-42110. | |
| Deschloroclozapine dihydrochloride | Deschloroclozapine dihydrochloride, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist. Deschloroclozapine binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively. [11C]-Deschloroclozapine is developed as a promising PET tracer for DREADD imaging[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-42110A. | |
| N-Desmethyl 8-Chloro-5H-dibenzo[b, e][1, 4]diazepine Clozapine-d8 | N-Desmethyl 8-Chloro-5H-dibenzo[b, e][1, 4]diazepine Clozapine-d8. Group: Biochemicals. Alternative Names: 11, 11'-(1, 4-Piperazinediyl)bis[8-chloro-5H-dibenzo[b, e][1, 4]diazepine-d8. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C30H16D8Cl2N6, Molecular Weight: 547.51. US Biological Life Sciences. | Worldwide |
| N-Desmethylclozapine | N-Desmethylclozapine is a major active metabolite of the atypical antipsychotic agent Clozapine. N-Desmethylclozapine is a potent, allosteric and partial M1 receptors agonist ( EC 50 =115 nM) and is able to potentiate hippocampal N-methyl-d-aspartate (NMDA) receptor currents through M1 receptor activation. N-Desmethylclozapine is also a δ-opioid agonist [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Norclozapine; Desmethylclozapine; Normethylclozapine. CAS No. 6104-71-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-G0021. | |
| 1-(8-Chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b, e][1, 4]diazepin-5-yl)ethanone | 1-(8-Chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b, e][1, 4]diazepin-5-yl)ethanone is an impurity of Clozapine, which is an antipsychotic. Group: Biochemicals. Grades: Highly Purified. CAS No. 1025951-76-1. Pack Sizes: 50mg, 250mg. Molecular Formula: C20H21ClN4O, Molecular Weight: 368.86. US Biological Life Sciences. | Worldwide |
| Chlorprothixene hydrochloride | Chlorprothixene hydrochloride is the hydrochloride salt form of chlorprothixene, a typical thioxanthine antipsychotic that functions by antagonizing dopamine D2 receptors. It can block a subset of GABAA receptors in rat cortex that is also blocked by clozapine. It exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors. It has also been shown to be effective against P. falciparum growth with an EC50 value of 1.7 μM. Synonyms: cis-Chlorprothixene; NSC 169899; Minithixen hydrochloride; Truxal hydrochloride; NSC 56379; NSC 78193; (3Z)-3-(2-chlorothioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine; hydrochloride. Grade: ≥98%. CAS No. 6469-93-8. Molecular formula: C18H18ClNS·HCl. Mole weight: 352.3. |  |
| Clofop | Clofop. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Clofop;LABOTEST-BB LT00239222;2-[4-(4-CHLORO-BENZOYL)-PHENOXY]-2-METHYL-PROPIONIC ACID;2-[4-(4-chlorophenoxy)phenoxy]-propanoic acid;SALOR-INT L498335-1EA;Fenofibric;2-(4-(4'-chlorphenoxy)-phenoxy)-propionsaeure;2-(p-(p-chlorophenoxy)phenoxy)-propionic a. Product Category: Heterocyclic Organic Compound. CAS No. 26129-32-8. Molecular formula: C15H13ClO4. Mole weight: 292.72. Purity: 0.96. IUPACName: 2-[4-(4-chlorophenoxy)phenoxy]propanoic acid. Canonical SMILES: CC(C(=O)O)OC1=CC=C(C=C1)OC2=CC=C(C=C2)Cl. Density: 1.306 g/cm³. Product ID: ACM26129328. Alfa Chemistry ISO 9001:2015 Certified. Categories: Clozapine. |  |
| Clothiapine | Clothiapine, an atypical antipsychotic agent, shares with clozapine its strong antiserotonergic properties [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2058-52-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-117083. | |
| GMC 1-116 | GMC 1-116 is a metabolite of clozapine with weak 5-HT2 affinity and high M1 affinity (IC50 = 27 nM). Synonyms: 11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-8-ol; 8-Hydroxyclozapine; AC1L9SL1; 6-(4-methylpiperazin-1-yl)-5H-benzo[b][1,4]benzodiazepin-3-ol. Grade: 99%. CAS No. 63687-94-5. Molecular formula: C18H20N4O. Mole weight: 308.38. | |
| GMC 1-165 | GMC 1-165 is an analogue of clozapine with 5-HT2A/2C and hM1 receptor affinities. Synonyms: 11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-2-ol; 6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepin-8-ol. Grade: 99%. CAS No. 156632-07-4. Molecular formula: C18H20N4O. Mole weight: 308.38. | |
| GMC 61-39 | GMC 61-39 is a clozapine-like atypical antipsychotic. Uses: Atypical antipsychotic. Synonyms: [3-chloro-6-(4-methylpiperazin-1-yl)-5H-benzo[b][1,4]benzodiazepin-8-yl] trifluoromethanesulfonate. Grade: 98%. CAS No. 234113-94-1. Molecular formula: C19H18ClF3N4O3S. Mole weight: 474.88. | |
| Quetiapine | Quetiapine, an thiazepin-analogue of Clozapine, could be effective in the treatment for schizophrenia and major depressive disorder for behaving as a 5HT-2 and D2 receptor antagonist. Uses: Quetiapine could be effective in the treatment for schizophrenia and major depressive disorder for behaving as a 5ht-2 and d2 receptor antagonist. Synonyms: QUETIAPINE-D4 FUMARATE; QUETIAPIN; 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-ethanol; Quetiapine; 11-[4-[2-(2-Hydroxyethoxy)ethyl]piperazino]dibenzo[b,f][1,4]thiazepine; 2-[2-[4-[Dibenzo[b,f][1,4]thiazepin-11-yl]piperazin-1-yl]ethoxy]etha. Grade: ≥98%. CAS No. 111974-69-7. Molecular formula: C21H25N3O2S. Mole weight: 383.51. | |
| Sonepiprazole | A selective D4 dopamine antagonist that exhibits low affinity at other monoamine receptors (Ki > 2000 nM). Induces c-fos gene expression in medial prefrontal cortex in a similar manner to Clozapine. Group: Biochemicals. Alternative Names: 4- [4- [2- [ (1S) -3, 4-Dihydro-1H-2-benzopyran-1-yl] ethyl] -1-piperazinyl] benzenesulfonamide; PNU 101387; U 101387; (S) -4- [4- [2- (3, 4-Dihydro-1H-2-benzopyran-1-yl) ethyl] -1-piperazinyl] benzenesulfonamide; PF-05191680. Grades: Highly Purified. CAS No. 170858-33-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
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