Clozapine Suppliers USA
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Product | Description | |
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Clozapine Quick inquiry Where to buy Suppliers range | 25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C18H19ClN4. CAS No. 5786-21-0. Prepack ID 66826682-25mg. Molecular Weight 326.82. See USA prepack pricing. | |
Clozapine Quick inquiry Where to buy Suppliers range | Clozapine. CAS No. 5786-21-0. Categories: Clozapine. | |
Clozapine Quick inquiry Where to buy Suppliers range | Clozapine is an atypical antipsychotic drug by acting as a 5-HT antagonist, used in the treatment of schizophrenia. Uses: Antipsychotic agents; gaba antagonists; serotonin antagonists. Synonyms: HF 1854; HF1854; HF-1854; LX 100-129; LX-100-129; LX100-129. Grades: >98%. CAS No. 5786-21-0. Molecular formula: C18H19ClN4. Mole weight: 326.82. | |
Clozapine Quick inquiry Where to buy Suppliers range | Clozapine. Uses: For analytical and research use. Group: Pharmacopeia & Metrological Institutes Standards; Fluorescence/Luminescence Spectroscopy; API Standards; British Pharmacopoeia; European Pharmacopoeia (Ph. Eur.); Pharmaceutical Toxicology; Pharmacopoeial Standards. Alternative Names: 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine, Azaleptin, Clozapine, Klozapol, Apo-Clozapine, Leponex, HF 1854, Cloril, Clozapin, Fazaclo, Sizopin, Iprox, Azaleptine, Clozapex, Asaleptin,5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methyl-1-piperazinyl)-, Clozaril. CAS No. 5786-21-0. IUPAC Name: 3-chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine. Molecular formula: C18H19ClN4. Mole weight: 326.82. Catalog: APS5786210. SMILES: CN1CCN (CC1)C2=Nc3cc (Cl)ccc3Nc4ccccc24. Format: Neat. Product Type: API. | |
Clozapine-5-N-Glucuronide Quick inquiry Where to buy Suppliers range | Clozapine 5-N-glucuronide is a metabolite of Clozapine, an antipsychotic. Synonyms: Clozapine 5-N-glucuronide; 390651-03-3; Clozapine-5-N-Glucuronide; 6-[3-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzodiazepin-11-yl]-3,4,5-trihydroxyoxane-2-carboxylic acid. Grades: > 95%. CAS No. 390651-03-3. Molecular formula: C24H27ClN4O6. Mole weight: 502.95. | |
Clozapine-D4 solution Quick inquiry Where to buy Suppliers range | 100 μg/mL in methanol, ampule of 1 mL, certified reference material. Group: Certified Reference Materials (CRMs). CAS No. 204395-52-8. Molecular Formula: 330.85. | |
Clozapine-d8 (8-Chloro-11-(4-methyl-1-piperazinyl-d8)-5H-dibenzo[b, e][1, 4]diazepine, HF-1854-d8, Liponex-d8) Quick inquiry Where to buy Suppliers range | An antipsychotic.A representative lot was 92% d8, 8% d7. Group: Biochemicals. Alternative Names: 8-Chloro-11-(4-methyl-1-piperazinyl-d8)-5H-dibenzo[b, e][1, 4]diazepine; HF-1854-d8; Liponex-d8. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Clozapine EP Impurity B Quick inquiry Where to buy Suppliers range | 11,11'-(Piperazine-1,4-diyl)bis(8-chloro-5H-dibenzo[b,e][1,4]-diazepine) is an impurity in commercial preparations of Clozapine. Synonyms: 11,11'-(Piperazine-1,4-diyl)bis(8-chloro-5H-dibenzo[b,e][1,4]-diazepine). Grades: > 95%. CAS No. 263366-81-0. Molecular formula: C30H24Cl2N6. Mole weight: 539.46. | |
Clozapine EP Impurity D Quick inquiry Where to buy Suppliers range | [2-[(2-Amino-4-chlorophenyl)amino]phenyl](4-methyl-1-piperazinyl)methanone is used in the synthesis of substituted dibenzodiazepines. It is also an impurity in the synthesis of Clozepine, an antipsychotic. Synonyms: [2-[(2-Amino-4-chlorophenyl)amino]phenyl](4-methyl-1-piperazinyl)methanone; 1-[2-[(2-Amino-4-chlorophenyl)amino]benzoyl]-4-methylpiperazine. Grades: > 95%. CAS No. 65514-71-8. Molecular formula: C18H21ClN4O. Mole weight: 344.84. | |
Clozapine for peak identification Quick inquiry Where to buy Suppliers range | Clozapine for peak identification. Uses: For analytical and research use. Group: European Pharmacopoeia (Ph. Eur.); Pharmacopoeial Standards. Alternative Names: Leponex, Clozapine, Asaleptin, Clozapin, HF 1854, Azaleptine, Klozapol, Fazaclo, Clozaril, Clozapex, Apo-Clozapine, Iprox, Sizopin, 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine, Cloril, Azaleptin,5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methyl-1-piperazinyl)-. CAS No. 5786-21-0. IUPAC Name: 3-chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine. Molecular formula: C18H19ClN4. Mole weight: 326.82. Catalog: APS5786210A. SMILES: CN1CCN (CC1)C2=Nc3cc (Cl)ccc3Nc4ccccc24. Format: Mixture. Product Type: Other. Shipping: Room Temperature. | |
Clozapine hydrochloride Quick inquiry Where to buy Suppliers range | Clozapine (HF 1854) is an antipsychotic used to treat schizophrenia. Clozapine is a potent antagonist of dopamine and a number of other receptors. Clozapine is also a potent and selective agonist at the muscarinic M4 receptor. Clozapine is a partial agonist of the serotonin (5-HT) receptor subtype 5-HT1A. It also binds to the 5-HT2A, 5-HT2C, 5-HT3, 5-HT6, and 5-HT7 receptors, as well as the histamine H1 and α1-adrenergic receptors. Synonyms: 8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine dihydrochloride; HF 1854 dihydrochloride. Grades: ≥98%. Molecular formula: C18H19ClN4·2HCl. Mole weight: 399.74. | |
Clozapine Impurity A Quick inquiry Where to buy Suppliers range | 8-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]-diazepin-11-one is a useful intermediate for the preparation of pharmaceutical actives and fine chemicals. Synonyms: 8-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]-diazepin-11-one. Grades: > 95%. CAS No. 50892-62-1. Molecular formula: C13H9ClN2O. Mole weight: 244.68. | |
Clozapine N-oxide Quick inquiry Where to buy Suppliers range | Clozapine N-oxide. Group: Heterocyclic Organic Compound. Alternative Names: e)(1,4)diazepine,8-chloro-11-(4-methyl-1-piperazinyl)-5h-dibenzo(n-oxide;CLOZAPINE N-OXIDE;8-CHLORO-11-[4-METHYL-1-PIPERAZINYL]-5H-DIBENZO[B,E][1,4]DIAZEPINE N-OXIDE;Clozapine N-oxide solution;Clozapine N-oxide Methanol Adduct. CAS No. 34233-69-7. Product ID: ACM34233697. Molecular formula: C18H19ClN4O. Mole weight: 342.82. Melting Point: 190-248°C. | |
Clozapine N-Oxide Quick inquiry Where to buy Suppliers range | Clozapine N-oxide is a major metabolite of clozapine, and acts as an antagonist of 5-HT receptor. Uses: Antipsychotic agents. Synonyms: 3-chloro-6-(4-methyl-4-oxidopiperazin-4-ium-1-yl)-11H-benzo[b][1,4]benzodiazepine. Grades: >98%. CAS No. 34233-69-7. Molecular formula: C18H19ClN4O. Mole weight: 342.827. | |
CLOZAPINE-N-OXIDE Quick inquiry Where to buy Suppliers range | Clozapine N-oxide, 34233-69-7, Clozapine-N-oxide, Clozapine (N-oxide), C18H19ClN4O, 3-chloro-6-(4-methyl-4-oxidopiperazin-4-ium-1-yl)-11H-benzo[b][1,4]benzodiazepine, UNII-MZA8BK588J, CHEMBL1688, MZA8BK588J, VUFB-12426, NSC-750266, 4-(8-chloro-5H-dibenzo[b,e][1,4]diazepin-11-yl)-1-methylpiperazine 1-oxide, N-Oxyclozapine, 5H-DIBENZO(B,E)(1,4)DIAZEPINE, 8-CHLORO-11-(4-METHYL-4-OXIDO-1-PIPERAZINYL)-, 5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methyl-4-oxido-1-piperazinyl)-, SCHEMBL9014028, DTXSID50955778, CHEBI:169893, BCP28618, EX-A2353, BDBM50279241, HB1807, NSC750266, Clozapine N-oxide (CNO) (freebase), AKOS005066164, CS-1618, NSC 750266, Clozapine N-oxide dihydrochloride- Bio-X, BC161997, BC162765, HY-17366, FT-0665138, W18756, J-019512, Q27284305, 5H-Dibenzo[b,4]diazepine, 8-chloro-11-(4-methyl-1-piperazinyl)-, N-oxide, 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,4]diazepine N-oxide, (E)-4-(8-chloro-5H-dibenzo[b,e][1,4]diazepin-11-yl)-1-methylpiperazine 1-oxide, 8-Chloro-11-(4-methyl-4-oxido-1-pip erazinyl)-5H-dibenzo[b,e][1,4]diazepine, 8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methyl-4-oxo-4lambda~5~-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine. | |
Clozapine N-oxide dihydrochloride Quick inquiry Where to buy Suppliers range | Clozapine N-oxide dihydrochloride is a water-soluble salt of Clozapine N-oxide. Clozapine N-oxide is a major metabolite of clozapine and an activator of designer receptors exclusively activated by designer drugs (DREADDs) derived from human muscarinic acetylcholine receptors. It exhibits improved bioavailability (6 - 7-fold higher plasma concentration) compared with CNO, with less conversion to clozapine in animal studies. Synonyms: 8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine dihydrochloride; CNO. Grades: ≥99% by HPLC. CAS No. 2250025-93-3. Molecular formula: C18H19ClN4O·2HCl. Mole weight: 415.74. | |
Clozapine solution Quick inquiry Where to buy Suppliers range | 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material. Group: Certified Reference Materials (CRMs). CAS No. 5786-21-0. Molecular Formula: 326.82. | |
N-Desmethyl 8-Chloro-5H-dibenzo[b, e][1, 4]diazepine Clozapine-d8 Quick inquiry Where to buy Suppliers range | N-Desmethyl 8-Chloro-5H-dibenzo[b, e][1, 4]diazepine Clozapine-d8. Group: Biochemicals. Alternative Names: 11, 11'-(1, 4-Piperazinediyl)bis[8-chloro-5H-dibenzo[b, e][1, 4]diazepine-d8. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C30H16D8Cl2N6, Molecular Weight: 547.51. US Biological Life Sciences. | Worldwide |
N-Desmethyl clozapine Quick inquiry Where to buy Suppliers range | N-Desmethyl clozapine is a metabolite of clozapine, an atypical antipsychotic drug that acts as a 5-HT antagonist. Synonyms: Norclozapine; Desmethylclozapine; 3-chloro-6-piperazin-1-yl-11H-benzo[b][1,4]benzodiazepine. Grades: ≥98%. CAS No. 6104-71-8. Molecular formula: C17H17ClN4. Mole weight: 312.80. | |
N-DESMETHYL CLOZAPINE Quick inquiry Where to buy Suppliers range | N-Desmethylclozapine, Norclozapine, 6104-71-8, Desmethylclozapine, Normethylclozapine, N-desmethyl clozapine, Demethylclozapine, NDMC, N-desmethyl-clozapine, 8-Chloro-11-(1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine, N-DEMETHYLCLOZAPINE, CHEMBL845, UNII-1I9001LWY8, 3-chloro-6-piperazin-1-yl-11H-benzo[b][1,4]benzodiazepine, 8-chloro-11-(piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine, CHEBI:64050, ACP 104, 1I9001LWY8, 8-Chloro-11-piperazin-1-yl-5H-dibenzo[b,e][1,4]diazepine, Norclozapine;Desmethylclozapine;Normethylclozapine, 8-Chloro-11-(1-piperazinyl)-5H-dibenzo[b,E][1,4]diazepine, 8-chloro-11-piperazin-1-yl-5H-dibenzo(B,E)(1,4)diazepine, 5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(1-piperazinyl)-, 5H-Dibenzo(b,e)(1,4)diazepine, 8-chloro-11-(1-piperazinyl)-, Clozapine-M nor, MFCD00210189, Tocris-1007, D0K4HW, GTPL333, SCHEMBL678149, SCHEMBL781423, DTXSID0042616, BDBM82478, CHEBI:92174, Desmethylclozapine (Norclozapine), ACP-104, C17-H17-Cl-N4, HMS3261I18, HMS3267M21, HMS3411P14, HMS3675P14, BCP30683, CAS_2820, HY-G0021, NSC_2820, Tox21_500448, BDBM50122054, AKOS015961221, CCG-221752, CS-6103, LP00448, SDCCGSBI-0633715.P001, NCGC00024936-01, NCGC00024936-02, NCGC00024936-03, NCGC00024936-06, NCGC00261133-01, NCGC00390290-01, AC-13127, CLOZAPINE IMPURITY C [USP IMPURITY], D5844, FT-0666152, EN300-6732832, SR-01000597458, Q5264612, SR-01000597458-1, BRD-K10042277-001-02-7, BRD-K10042277-001-04-3, Desmethylclozapine (Norclozapine) 1.0 mg/ml in Methanol, Z2242153190, 3-chloro-6-piperazin-1-yl-5H-benzo[c][1,5]benzodiazepine, 8-Chloro-11-(1-piperazinyl)-5H-dibenzo[b,e]-[1,4]diazepine, (E)-8-chloro-11-(piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine, 8-Chloro-11-(1-piperazinyl)-5H-dibenzo[b,E][1,4]diazepine #, Norclozapine; Desmethylclozapine; Normethylclozapinee; ACP-104; ACP104; ACP 104, 6-chloro-10-(piperazin-1-yl)-2,9-diazatricyclo[9.4.0.0,3,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaene. | |
1-(8-Chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b, e][1, 4]diazepin-5-yl)ethanone Quick inquiry Where to buy Suppliers range | 1-(8-Chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b, e][1, 4]diazepin-5-yl)ethanone is an impurity of Clozapine, which is an antipsychotic. Group: Biochemicals. Grades: Highly Purified. CAS No. 1025951-76-1. Pack Sizes: 50mg, 250mg. Molecular Formula: C20H21ClN4O, Molecular Weight: 368.86. US Biological Life Sciences. | Worldwide |
Chlorprothixene hydrochloride Quick inquiry Where to buy Suppliers range | Chlorprothixene hydrochloride is the hydrochloride salt form of chlorprothixene, a typical thioxanthine antipsychotic that functions by antagonizing dopamine D2 receptors. It can block a subset of GABAA receptors in rat cortex that is also blocked by clozapine. It exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors. It has also been shown to be effective against P. falciparum growth with an EC50 value of 1.7 μM. Synonyms: cis-Chlorprothixene; NSC 169899; Minithixen hydrochloride; Truxal hydrochloride; NSC 56379; NSC 78193; (3Z)-3-(2-chlorothioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine;hydrochloride. Grades: ≥98%. CAS No. 6469-93-8. Molecular formula: C18H18ClNS·HCl. Mole weight: 352.3. | |
GMC 1-116 Quick inquiry Where to buy Suppliers range | GMC 1-116 is a metabolite of clozapine with weak 5-HT2 affinity and high M1 affinity (IC50 = 27 nM). Synonyms: 11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-8-ol; 8-Hydroxyclozapine; AC1L9SL1; 6-(4-methylpiperazin-1-yl)-5H-benzo[b][1,4]benzodiazepin-3-ol. Grades: 99%. CAS No. 63687-94-5. Molecular formula: C18H20N4O. Mole weight: 308.38. | |
GMC 1-165 Quick inquiry Where to buy Suppliers range | GMC 1-165 is an analogue of clozapine with 5-HT2A/2C and hM1 receptor affinities. Synonyms: 11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-2-ol; 6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepin-8-ol. Grades: 99%. CAS No. 156632-07-4. Molecular formula: C18H20N4O. Mole weight: 308.38. | |
GMC 61-39 Quick inquiry Where to buy Suppliers range | GMC 61-39 is a clozapine-like atypical antipsychotic. Uses: Atypical antipsychotic. Synonyms: [3-chloro-6-(4-methylpiperazin-1-yl)-5H-benzo[b][1,4]benzodiazepin-8-yl] trifluoromethanesulfonate. Grades: 98%. CAS No. 234113-94-1. Molecular formula: C19H18ClF3N4O3S. Mole weight: 474.88. | |
Isoclozapine Quick inquiry Where to buy Suppliers range | Isoclozapine, a 2-Cl analogue of clozapine, is a 5-HT antagonist as a typical antipsychotic. Synonyms: 2-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine. Grades: 98%. CAS No. 1977-8-8. Molecular formula: C18H19ClN4. Mole weight: 326.82. | |
PNU 96415E Quick inquiry Where to buy Suppliers range | PNU 96415E, chemically unrelated to clozapine, exhibits high affinity for dopamine D4 and serotonergic 5-HT2A receptors and relatively weak affinity at D2 receptors (Ki= 3.0, 5.8, 134, 181, 199, 240, 411 and > 678 nM for D4, 5-HT2A, 5-HT1A, α1, D2, D3, D1, α2 and muscarinic receptors respectively). PNU-96415E has a profile of behavioral effects in rodents very similar to that of clozapine, including complete discriminative stimulus generalization. Synonyms: PNU 96415E; PNU96415E; PNU-96415E; 1-[2-(3,4-Dihydro-1H-2-benzopyran-1-yl)ethyl]-4-(4-fluorophenyl)piperazine dihydrochloride. Grades: ≥98% by HPLC. CAS No. 170856-41-4. Molecular formula: C21H25FN2O.2HCl. Mole weight: 413.36. | |
Sonepiprazole Quick inquiry Where to buy Suppliers range | Sonepiprazole is a selective, brain penetrating and orally bioactive antagonist for the rat and human dopamine D4 receptor (Ki = 10 nM) with low affinity at other monoamine receptors (Ki > 2000 nM). Sonepiprazole was shown to induce c-fos gene expression in medial prefrontal cortex in a similar manner to clozapine. Synonyms: 4-[4-[2-[(1S)-3,4-Dihydro-1H-2-benzopyran-1-yl)ethyl]-1-piperazinyl]-benzenesulfonamide. Grades: ≥98% by HPLC. CAS No. 170858-33-0. Molecular formula: C21H27N3O3S. Mole weight: 401.52. | |
Sonepiprazole Quick inquiry Where to buy Suppliers range | A selective D4 dopamine antagonist that exhibits low affinity at other monoamine receptors (Ki > 2000 nM). Induces c-fos gene expression in medial prefrontal cortex in a similar manner to Clozapine. Group: Biochemicals. Alternative Names: 4- [4- [2- [ (1S) -3, 4-Dihydro-1H-2-benzopyran-1-yl] ethyl] -1-piperazinyl] benzenesulfonamide; PNU 101387; U 101387; (S) -4- [4- [2- (3, 4-Dihydro-1H-2-benzopyran-1-yl) ethyl] -1-piperazinyl] benzenesulfonamide; PF-05191680. Grades: Highly Purified. CAS No. 170858-33-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |