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The prokaryotic cytidine monophosphate kinase specifically phosphorylates CMP (or dCMP), using ATP as the preferred phosphoryl donor. Unlike EC 2.7.4.14, a eukaryotic enzyme that phosphorylates UMP and CMP with similar efficiency, the prokaryotic enzyme phosphorylates UMP with very low rates, and this function is catalysed in prokaryotes by EC 2.7.4.22, UMP kinase. The enzyme phosphorylates dCMP nearly as well as it does CMP. Group: Enzymes. Synonyms: prokaryotic cytidylate kinase; deoxycytidylate kinase; dCMPkinase; deoxycytidine monophosphokinase. Enzyme Commission Number: EC 2.7.4.25. dCMPkinase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3207; (d)CMPkinase; EC 2.7.4.25; prokaryotic cytidylate kinase; deoxycytidylate kinase; dCMPkinase; deoxycytidine monophosphokinase. Cat No: EXWM-3207.
(d)CMPKinase (Crude Enzyme)
This enzyme specifically phosphorylates CMP (or dCMP). This product with the indicated enzyme activity was briefly purified from engineered E. coli. Applications: Biotechnology. Group: Enzymes. Synonyms: prokaryotic cytidylate kinase; deoxycytidylate kinase; dCMPkinase; deoxycytidine monophosphokinase. Enzyme Commission Number: EC 2.7.4.25. dCMPkinase. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. prokaryotic cytidylate kinase; deoxycytidylate kinase; dCMPkinase; deoxycytidine monophosphokinase. Pack: 100ml. Cat No: NATE-1828.
UMP/CMPkinase
This eukaryotic enzyme is a bifunctional enzyme that catalyses the phosphorylation of both CMP and UMP with similar efficiency. dCMP can also act as acceptor. Different from the monofunctional prokaryotic enzymes EC 2.7.4.25, CMPkinase and EC 2.7.4.22, UMP kinase. Group: Enzymes. Synonyms: cytidylate kinase; deoxycytidylate kinase; CTP:CMP phosphotransferase; dCMPkinase; deoxycytidine monophosphokinase; UMP-CMPkinase; ATP:UMP-CMP phosphotransferase; pyrimidine nucleoside monophosphate kinase; uridine monophosphate-cytidine monophosphate phosphotransferase. Enzyme Commission Number: EC 2.7.4.14. CAS No. 37278-21-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3195; UMP/CMPkinase; EC 2.7.4.14; 37278-21-0; cytidylate kinase; deoxycytidylate kinase; CTP:CMP phosphotransferase; dCMPkinase; deoxycytidine monophosphokinase; UMP-CMPkinase; ATP:UMP-CMP phosphotransferase; pyrimidine nucleoside monophosphate kinase; uridine monophosphate-cytidine monophosphate phosphotransferase. Cat No: EXWM-3195.
2'-Deoxycytidine-5'-monophosphate
2'-Deoxycytidine-5'-monophosphate is a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase to form dCDP during nucleic acid synthesis. Synonyms: dCMP; deoxycytidylic acid; deoxycytidine monophosphate. Grades: 95%. CAS No. 1032-65-1. Molecular formula: C9H14N3O7P. Mole weight: 307.20.
CMPD-1
CMPD-1, also called MK2a Inhibitor, inhibits tubulin polymerisation. It inhibit p38α-mediated MK2a phosphorylation (apparent Ki = 330 nM). Synonyms: CMPD1; CMPD-1; CMPD 1; IN1225; IN-1225; IN 1225; 4-[4-(2-fluorophenyl)phenyl]-N-(4-hydroxyphenyl)butanamide; MK2a Inhibitor; MAPKAPK2a Inhibitor; CMPD1; CHEMBL235658; 41179-33-3; IN1225; 4-(2' -Fluorobiphenyl-4-yl)-N-(4-hydroxyphenyl)-butyramide; Mitogen-activated protein kinase-activated protein kinase 2a Inhibitor; MK2a Inhibitor_x000D_; SCHEMBL169905. CAS No. 41179-33-3. Molecular formula: C22H20FNO2. Mole weight: 349.4.
CMPD101
CMPD101 is a novel, potent and selective G-protein coupled receptor kinase 2 and 3 (GRK2/GRK3) inhibitor (IC50 values are 35 and 32 nM at GRK2 and GRK3 respectively). CMPD101 exhibits selectivity for GRK2/3 over GRK1/5 and reduces DAMGO-induced desensitization and internalization of μ-opioid receptors. CMPD101 has been shown to potentiate phosphatidylinositol 4,5-bisphosphate (PIP2) depletion and slow agonist-induced desensitization of protease-activated receptor 2 (PAR2). Group: Inhibitors. Alternative Names: CMPD101; CMPD 101; CMPD-101; Takeda101; Takeda-101; Takeda 101. CAS No. 865608-11-3. Molecular formula: C24H21F3N6O. Mole weight: 466.47. Appearance: Solid powder. Purity: >98%. IUPACName: 3-[[[4-Methyl-5- (4-pyridinyl) -4H-1, 2, 4-triazol-3-yl]methyl]amino]-N-[[2- (trifluoromethyl) phenyl]methyl]benzamide. Canonical SMILES: O=C (NCC1=CC=CC=C1C (F) (F)F)C2=CC=CC (NCC3=NN=C (C4=CC=NC=C4)N3C)=C2. Catalog: ACM865608113.
Cytidine 5'-diphosphate trisodium salt
Cytidine 5'-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: CDP. CAS No. 34393-59-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W008915.
Pyridone 6
Pyridone 6 is a potent and selective inhibitor of JAK1, JAK2, JAK3, and Tyk2, displaying significantly weaker affinities for other protein tyrosine kinases. It was shown to block IL-2 and IL-4-dependent proliferation of mouse T-cell lymphoma cells. Synonyms: Pyridone 6; Pyridone-6; Pyridone6; CMP 6; JAK Inhibitor I; Janus-Associated Kinase Inhibitor I. Grades: >98%. CAS No. 457081-03-7. Molecular formula: C18H16FN3O. Mole weight: 309.34.
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