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| Product | Description | |
|---|---|---|
| CMP-5 | CMP5 is a potent, selective and specific inhibitor of PRMT5, but has no activity against PRMT1, PRMT4 and PRMT7 enzymes. CMP5 selectively blocks S2Me-H4R3 by inhibiting the activity of PRMT5 methyltransferase on histone preparations. It prevents epstein-barr virus (EBV)-driven B-lymphocyte transformation, but does not affect normal B cells. Synonyms: 1-(9-ethyl-9H-carbazol-3-yl)-N-(pyridin-2-ylmethyl)methanamine; PRMT5-IN-5; N-[(9-ethyl-9H-carbazol-3-yl)methyl]-N-(2-pyridinylmethyl)amine; 9H-Carbazole-3-methanamine, 9-ethyl-N-(2-pyridinylmethyl)-. Grade: ≥98%. CAS No. 880813-42-3. Molecular formula: C21H21N3. Mole weight: 315.41. |  |
| CMP-5 | CMP-5 is a potent, specific, and selective PRMT5 inhibitor, while displays no activity against PRMT1, PRMT4, and PRMT7 enzymes. CMP-5 selectively blocks S2Me-H4R3 by inhibiting PRMT5 methyltransferase activity on histone preparations. CMP-5 prevents Epstein-Barr virus (EBV)-driven B-lymphocyte transformation but leaving normal B cells unaffected [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 880813-42-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120137. |  |
| CMP-5 2HCl | CMP-5 2HCl is a repellent. The EC100 of CMP-5 2HCl in vitro against H. contortus is 5 μM. Synonyms: 9H-Carbazole-3-methanamine, 9-ethyl-N-(2-pyridinylmethyl)-,hydrochloride (1:2). Grade: >98.0%. CAS No. 2309409-79-6. Molecular formula: C21H23Cl2N3. Mole weight: 388.34. | |
| CMP5 | CMP5 is a potent and selective PRMT5 inhibitor suppressing EBV-driven B-lymphocyte transformation while leaving normal B cells unaffected. Inhibition of PRMT5 effetively blocked recall T cell responses, reduced inflammation in delayed-type hypersensitivity and clinical disease in experimental autoimmune encephalomyelitis mouse models. Synonyms: CMP5; CMP 5; CMP-5; 1-(9-ethylcarbazol-3-yl)-N-(pyridin-2-ylmethyl)methanamine Hydrochloride; AKOS032401780. Grade: 99%. CAS No. 1030021-40-9. Molecular formula: C20H22N3.HCl. Mole weight: 351.87. | |
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