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CNQX, also known as FG9065, is a potent and competitive AMPA/kainate receptor antagonist and also antagonist at glycine modulatory site on NMDA receptor complex. Uses: Excitatory amino acid antagonists. Synonyms: 7-nitro-2,3-dioxo-1,4-dihydroquinoxaline-6-carbonitrile; 1,4-dihydro-2,3-dihydroxy-7-nitro-6-quinoxalinecarbonitrile; 6 Cyano 2,3 dihydroxy 7 nitroquinoxaline; 6 Cyano 7 nitroquinoxaline 2,3 dione; 6-Cyano-2,3-dihydroxy-7-nitroquinoxaline; 6-Cyano-7-nitroquinoxaline-2,3-dione; CNQX; FG 9065; FG-9065; FG9065. CAS No. 115066-14-3. Molecular formula: C9H4N4O4. Mole weight: 232.15.
CNQX
CNQX. Group: Biochemicals. Grades: Purified. CAS No. 115066-14-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
A potent and competitive antagonist for AMPA/kainate receptors (Ki = 0.6-2.11uM for GluA1-4 and Ki = 1.3-5.3uM for different subtypes of Kainate receptors) and a negative allosteric modulator atnMDA receptor glycine binding site. Widely used for assessing the functional roles of neurotransmission mediated by glutamate receptors in both normal and abnormal brain functions. Group: Biochemicals. Grades: Highly Purified. CAS No. 115066-14-3. Pack Sizes: 10mg. US Biological Life Sciences.
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CNQX disodium salt
CNQX disodium salt. Group: Biochemicals. Grades: Purified. CAS No. 479347-85-8. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences.
Worldwide
CNQX disodium salt
The sodium salt form of CNQX, which is an AMPA/kainate antagonist and could be used in studies of neurological disorders or damage. Synonyms: 6-Cyano-7-nitroquinoxaline-2,3-dione disodium. Grades: ≥99% by HPLC. CAS No. 479347-85-8. Molecular formula: C9H2N4O4Na2. Mole weight: 276.12.
A potent, competitive kainate/quisqualate (non-NMDA) receptor antagonist. IC50 of tritiated ligands to rat cortical membranes by CNQX: AMPA, Kainate and CPP are 0.3mM, 1.5mM, and 25mM, respectively. Group: Biochemicals. Alternative Names: CNQX. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
6-Cyano-7-nitroquinoxaline-2,3-dione
6-Cyano-7-nitroquinoxaline-2,3-dione. Group: Biochemicals. Alternative Names: 1, 2, 3, 4-Tetra hydro-7-nitro-2, 3-dioxo-6-quinoxalinecarbonitri le; CNQX; 6-Cyano-2,3-dihydroxy-7-nitroquinoxaline. Grades: Highly Purified. CAS No. 115066-14-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C9H4N4O4. US Biological Life Sciences.
Worldwide
ZK200775
Competitive AMPA/kainate antagonist. In rat cortical membranes, displays high affinity for [3H]-AMPA (Ki = 120 nM) and [3H]-CNQX (Ki = 32 nM) binding sites and low affinity for kainate and NMDA channel-associated binding sites (IC50 values range from 2.5 to 11 μM). Inhibits currents induced by AMPA, kainate and NMDA with IC50 values of 21 nM, 27 nM, and > 1 μM respectively. Displays anxiolytic, anticonvulsant and muscle relaxant activity in vivo. Synonyms: Fanapanel; MPQX; ZK-200775; ZK 200775; ZK200775. Grades: >98%. CAS No. 161605-73-8. Molecular formula: C14H15F3N3O6P. Mole weight: 409.25.
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