Cobimetinib Suppliers USA
Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
Product | Description | |
---|---|---|
Cobimetinib Quick inquiry Where to buy Suppliers range | Cobimetinib (GDC-0973, RG7420) is a potent, orally available and highly selective MEK1 inhibitor with IC50 of 4.2 nM. It shows more than 100-fold selectively for MEK1 over MEK2 when tested against a panel of more than 100 serine-threonine and tyrosine kinases and showed no significant inhibition when tested against a panel of more than 100 of serine-threonine and tyrosine kinases. Synonyms: XL518; GDC-0973; RG7420. Grades: ≥98%. CAS No. 934660-93-2. Molecular formula: C21H21F3IN3O2. Mole weight: 531.31. | |
Cobimetinib hemifumarate Quick inquiry Where to buy Suppliers range | Cobimetinib, also known as GDC-0973 and XL-518, is a novel selective MEK inhibitor, and the IC50value against MEK1 is 4.2 nM, with potential antineoplastic activity. Synonyms: Methanone, [3,?4-difluoro-2-[(2-fluoro-4-iodophenyl)?amino]?phenyl]?[3-hydroxy-3-(2S)?-2-piperidinyl-1-azetidinyl]?-, (2E)?-2-butenedioate (2:1). CAS No. 1369665-02-0. Molecular formula: C21H21F3IN3O2.1/2C4H4O4. Mole weight: 589.35. | |
Cobimetinib racemate Quick inquiry Where to buy Suppliers range | Cobimetinib racemate is a selective inhibitor of MEK. It is also known as mitogen activated protein kinase kinase (MAPKK) and is a key component of the RAS/RAF/MEK/ERK pathway, which is frequently activated in human tumors. Synonyms: GDC-0973 racemate; XL-518; GDC 0973 racemate; XL 518; GDC0973 racemate; XL518. Grades: >98%. CAS No. 934662-91-6. Molecular formula: C21H21F3IN3O2. Mole weight: 531.31. | |
Cobimetinib (R-enantiomer) Quick inquiry Where to buy Suppliers range | Cobimetinib (R-enantiomer) is a selective inhibitor of MEK. It is also known as mitogen activated protein kinase kinase (MAPKK) and is a key component of the RAS/RAF/MEK/ERK pathway, which is frequently activated in human tumors. Synonyms: GDC-0973 R-enantiomer; XL-518 R-enantiomer; GDC0973 R-enantiomer; XL518 R-enantiomer; GDC 0973 R-enantiomer; XL 518 R-enantiomer. Grades: >98%. CAS No. 934660-94-3. Molecular formula: C21H21F3IN3O2. Mole weight: 531.31. |