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| Product | Description | |
|---|---|---|
| Cocaine-D3 solution | 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms). |  |
| cocaine esterase | Rhodococcus sp. strain MB1 and Pseudomonas maltophilia strain MB11L can utilize cocaine as sole source of carbon and energy. Group: Enzymes. Synonyms: CocE; hCE2; hCE-2; human carboxylesterase 2. Enzyme Commission Number: EC 3.1.1.84. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3513; cocaine esterase; EC 3.1.1.84; CocE; hCE2; hCE-2; human carboxylesterase 2. Cat No: EXWM-3513. |  |
| Cocaine Multi-component Mixture solution | 250 ?g/mL each component in acetonitrile, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms). | |
| Cocaine N-oxide hydrochloride | 1.0 mg/mL in acetonitrile (as free base), ampule of 1 mL, certified reference material. Group: Certified reference materials (crms). | |
| 2'-Acetoxycocaine-d3 Hydrochloride | 2'-Acetoxycocaine-d3 Hydrochloride is labelled 2'-Acetoxycocaine Hydrochloride (A164870) which is a cocaine (C633500, HCl salt) analog, with a quicker effect onset than cocaine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C19H21D3ClNO6, Molecular Weight: 400.87. US Biological Life Sciences. |  Worldwide |
| 2'-Acetoxycocaine Hydrochloride | 2'-Acetoxycocaine Hydrochloride is is a cocaine (C633500, HCl salt) analog, with a quicker effect onset than cocaine. Group: Biochemicals. Grades: Highly Purified. CAS No. 197771-75-8. Pack Sizes: 5mg, 50mg. Molecular Formula: C19H24ClNO6, Molecular Weight: 397.85. US Biological Life Sciences. | Worldwide |
| 2'-Hydroxycocaine | 2'-Hydroxycocaine is a metabolite of Cocaine (C633500), which Inhibits the dopamine, norepinephrine, and serotonin transporters and is a local anesthetic. Measurement of hydroxycocaine metabolites in hair can be used as evidence of cocaine ingestion. Group: Biochemicals. Grades: Highly Purified. CAS No. 89339-17-3. Pack Sizes: 5mg, 10mg. Molecular Formula: C17H21NO5, Molecular Weight: 319.35. US Biological Life Sciences. | Worldwide |
| 2'-Hydroxycocaine-d3 | 2'-Hydroxycocaine-d3 is the isotopically labelled form of 2'-Hydroxycocaine (H922195), which is a metabolite of Cocaine (C633500) that Inhibits the dopamine, norepinephrine, and serotonin transporters and is a local anesthetic. Measurement of hydroxycocaine metabolites in hair can be used as evidence of cocaine ingestion. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C17H18D3NO5, Molecular Weight: 322.37. US Biological Life Sciences. | Worldwide |
| Benzoylecgonine (BSA) (BE, Cocaine) | Benzoylecgonine is the predominant cocaine metabolite. The compound is not biologically active, but is used as an indicator of cocaine use. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 1- (2-Methoxyphenyl) piperazine | A piperazine derivative and a selective antagonist at D3 receptors that influences the expression of cocaine-induced conditioned place preference (CPP). Group: Biochemicals. Grades: Highly Purified. CAS No. 35386-24-4. Pack Sizes: 1g, 10g, 25g, 50g. Molecular Formula: C??H??N?O. US Biological Life Sciences. | Worldwide |
| [1R-(2-endo, 3-exo)]-8-Methyl-3-phenyl-8-azabicyclo[3. 2. 1]octane-2-carboxylic Acid Methyl Ester | [1R-(2-endo, 3-exo)]-8-Methyl-3-phenyl-8-azabicyclo[3. 2. 1]octane-2-carboxylic Acid Methyl Ester is an intermediate in the synthesis of RTI-55 (R701010), a semi-synthetic alkaloid that is a cocaine analogue belonging to the phenyltropane group. Group: Biochemicals. Alternative Names: (1R, 2R, 3S, 5S)-8-Methyl-3-phenyl-8-azabicyclo[3. 2. 1]octane-2-carboxylic Acid Methyl Ester. Grades: Highly Purified. CAS No. 50370-54-2. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| (1R,3S,5S)-Methyl 3-(4-Chlorophenyl)-8-methyl-8-azabicyclo[3. 2. 1]octane-2-carboxylate | (1R,3S,5S)-Methyl 3-(4-Chlorophenyl)-8-methyl-8-azabicyclo[3. 2. 1]octane-2-carboxylate is an intermediate in synthesizing RTI-113 (R701110), a 3-phenyltropane analogue that acts as a potent and selective dopamine uptake inhibitor. RTI-113 has been shown to reduce cocaine self-administration at high occupancy of dopamine transporter. Studies suggest that RTI-113 and its analogs may be useful tools for developing potential agonist therapies for cocaine dependence. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 100mg. Molecular Formula: C16H20ClNO2. US Biological Life Sciences. | Worldwide |
| (1R-endo)-8-Methyl-3-oxo-8-azabicyclo[3. 2. 1]octane-2-carboxylic Acid Methyl Ester (2R,3R)-2,3-Dihydroxybutanedioate | (1R-endo)-8-Methyl-3-oxo-8-azabicyclo[3. 2. 1]octane-2-carboxylic Acid Methyl Ester (2R,3R)-2,3-Dihydroxybutanedioate is an intermediate in the synthesis of cocaine isomers at the cocaine receptor. Group: Biochemicals. Grades: Highly Purified. CAS No. 131722-67-3. Pack Sizes: 1g, 5g. Molecular Formula: C14H21NO9. US Biological Life Sciences. | Worldwide |
| 2-(Methoxycarbonyl)-3-tropinone | rac-8-Methyl-3-oxo-8-azabicyclo[3. 2. 1]octane-2-carboxylic Acid Methyl Ester is an intermediate in the synthesis of cocaine isomers at the cocaine receptor. Group: Biochemicals. Grades: Highly Purified. CAS No. 36127-17-0. Pack Sizes: 1g, 2.5 g. Molecular Formula: C10H15NO3. US Biological Life Sciences. | Worldwide |
| (2S)-2-Hydroxy-1-propyl Methanesulfonate | Used in the preparation of labeled cocaine analogs. Group: Biochemicals. Alternative Names: (2R)-1,2-Propanediol 1-Methanesulfonate. Grades: Highly Purified. CAS No. 262423-83-6. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 3-[[[3-[4-[ (Methylsulfonyl) amino]phenyl]-4-oxo-4H-chromen-7-yl]oxy]methyl]benzoic Acid | 3-[[[3-[4-[ (Methylsulfonyl) amino]phenyl]-4-oxo-4H-chromen-7-yl]oxy]methyl]benzoic Acid is a highly selective reversible aldehyde dehydrogenase 2 (ALDH-2) inhibitor that reduce alcohol and cocaine intake in rats. It also has anxiolytic properties as well as reduces excessive alcohol drinking. Group: Biochemicals. Grades: Highly Purified. CAS No. 1005334-57-5. Pack Sizes: 1mg, 5mg. Molecular Formula: C24H19NO7S, Molecular Weight: 465.48. US Biological Life Sciences. | Worldwide |
| 3-Azabicyclo[3.1.0]hexane Hydrochloride | 3-Azabicyclo[3.1.0]hexane Hydrochloride, a significant substance in the field of pharmaceuticals, is employed in the synthesis of therapeutic agents to cure disorders related to the central nervous system. Due to its high selectivity and robust inhibition of synaptic vesicular monoamine transporter, it is an essential regulator of neurotransmitter systems responsible for monoamine. It exhibits promising potential in mitigating Parkinson's disease and cocaine addiction, exhibiting marked implications in the treatment sector. CAS No. 73799-64-1. Molecular formula: C5H10ClN. Mole weight: 119.59. |  |
| 3-CPMT | 3-CPMT, a cocaine analogue, is a dopamine transporter blocker and has been found to be a weak psychomotor stimulant. Synonyms: 3-CPMT; 3 CPMT; 3CPMT; 3α-[(4-Chlorophenyl)phenylmethoxy] tropane hydrochloride. Grades: ≥99% by HPLC. CAS No. 14008-79-8. Molecular formula: C21H24ClNO.HCl. Mole weight: 378.34. | |
| ADX88178 | This active molecular is a selectiveMetabotropic glutamate receptor 4 agonist and modulator under the development of Addex Therapeutics. In the marble burying test, ADX88178 can reduce the number of buried marbles Meanwhile, in the EPM (elevated plus maze) test, it can also increase open-arm exploration, indicative of anxiolytic-like efficacy. Now, preclinical trials for Anxiety disorders, Cocaine abuse, Multiple sclerosis and Parkinson's diseas were on-going. Uses: Anxiety disorders; cocaine abuse; multiple sclerosis; parkinson's disease. Synonyms: ADX-88178; ADX 88178; ADX88178. SCHEMBL369060; GTPL6238; SCHEMBL 369060; GTPL 6238; SCHEMBL-369060; GTPL-6238; 5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)-1,3-thiazol-2-amine. Grades: 98%. CAS No. 1235318-89-4. Molecular formula: C12H12N6S. Mole weight: 272.33. | |
| Antalarmin hydrochloride | Antalarmin hydrochloride is the hydrochloride salt of antalarmin, which is a selective nonpeptide antagonist of the corticotropin-releasing hormone (CRH) receptor 1 with Ki value of 1 nM. It suppresses CRF-induced ACTH secretion and blocks CRF- and novelty-induced anxiety-like behavior in animal models of anxiety. It also can reduce cardiovascular, endocrinological and behavioral responses to stressful stimuli through its antagonism of central CRH signaling. It produces anti-inflammatory effects in arthritis models by reducing dose escalation in cocaine-addicted rats and suppresses stress-induced gastric ulceration related to irritable bowel syndrome. Synonyms: N-Butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Monohydrochloride; N-Butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Hydrochloride. Grades: ≥99% by HPLC. CAS No. 220953-69-5. Molecular formula: C24H35N4Cl. Mole weight: 415.01. | |
| BD 1008 dihydrobromide | BD 1008 dihydrobromide is a potent and selective σ receptor antagonist displaying 4-fold selectivity for σ1 over σ2. BD-1008 attenuates the toxicity and stimulant effects of cocaine, and can be used as the treatment of cocaine overdose and neuropathic pain after chemotherapy. Synonyms: BD1008 dihydrobromide; BD-1008 dihydrobromide; N-[2-(3,4-Dichlorophenyl)ethyl]-N-methyl-2-(1-pyrrolidinyl)ethylamine dihydrobromide; 1-Pyrrolidineethanamine, N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-, hydrobromide (1:2); 1-Pyrrolidineethanamine, N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-, dihydrobromide. Grades: ≥95%. CAS No. 138356-09-9. Molecular formula: C15H22Cl2N2.2HBr. Mole weight: 463.08. | |
| Benzoylecgonine tetrahydrate | drug standard. Group: Cocaine analogs standards. | |
| Benzoylnorecgonine | analytical standard. Group: Cocaine analogs standards. | |
| carboxylesterase | Wide specificity. The enzymes from microsomes also catalyse the reactions of EC 3.1.1.2 (arylesterase), EC 3.1.1.5 (lysophospholipase), EC 3.1.1.6 (acetylesterase), EC 3.1.1.23 (acylglycerol lipase), EC 3.1.1.28 (acylcarnitine hydrolase), EC 3.1.2.2 (palmitoyl-CoA hydrolase), EC 3.5.1.4 (amidase) and EC 3.5.1.13 (aryl-acylamidase). Also hydrolyses vitamin A esters. Group: Enzymes. Synonyms: ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyrate esterase; triacetin esterase; carboxyl ester h. Enzyme Commission Number: EC 3.1.1.1. CAS No. 9016-18-6. Esterase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3434; carboxylesterase; EC 3.1.1.1; 9016-18-6; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyrate esterase; triacetin esterase; carboxyl ester hydrolase; butyrate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxylic acid esterase; cocaine esterase. Cat No: EXWM-3434. | |
| Carboxylesterase 1 isoform b from Human, Recombinant | Carboxylesterase 1 is a member of a large multigene carboxylesterase family. These enzymes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolyze long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Applications: Delivers high catalytic activity, ideal for robust high-throughput screening assays including drug-drug interaction studies, and pharmacokinetic...er: EC 3.1.1.1. CAS No. 9016-18-6. Esterase. Activity: ≥500 units/mg protein. Storage: at -70°C. Form: Liquid. Source: Baculovirus infected BTI insect cells. Species: Human. EC 3.1.1.1; Esterase Isoenzyme 1; 9016-18-6; carboxylesterase; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyrate esterase; triacetin esterase; carboxyl ester hydrolase; butyrate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxyl | |
| Carboxylesterase 1 isoform c from Human, Recombinant | Carboxylesterase 1 is a member of a large multigene carboxylesterase family. These enzymes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolyze long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Applications: Delivers high catalytic activity, ideal for robust high-throughput screening assays including drug-drug interaction studies, and pharmacokinetic...er: EC 3.1.1.1. CAS No. 9016-18-6. Esterase. Activity: ≥1000 units/mg protein. Storage: at -70°C. Form: Liquid. Source: Baculovirus infected BTI insect cells. Species: Human. EC 3.1.1.1; Esterase Isoenzyme 1; 9016-18-6; carboxylesterase; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyrate esterase; triacetin esterase; carboxyl ester hydrolase; butyrate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxy | |
| Carboxylesterase 2 from Human, Recombinant | Member of a serine esterase family that hydrolyze ester and amide bonds. Carboxylesterase 2 is an endoplasmic reticulum-bound hydrolase that plays a critical role in xenobiotic detoxification and activation for ester-containing therapeutics. Carboxylesterase 2 is also involved in the detoxification of drugs such as heroin and cocaine. This enzyme is thought to play a role in lipid metabolism. Human carboxylesterase 2 (hCE-2) recognizes a substrate with a large alcohol group and small acyl group. Its substrate specificity may be restricted by a capability of acyl-hCE-2 conjugate formation due to the presence of conformational interference in the active site pocket. Carboxylesterases catalyze the biotransformation of several ester-containing drugs and prodrugs such as angiotensin-converting enzyme inhibitor (temocarpil, cilazapril), anti-tumor drugs (capecitabin) and narcotics. Group: Enzymes. Synonyms: EC 3.1.1.1; Carboxylesterase 2; CES2; CES2A1; CE-2; . Enzyme Commission Number: EC 3.1.1.1. CAS No. 9016-18-6. Purity: >95% (SDS-PAGE). Esterase. Mole weight: ~60 kDa. Activity: >30,000 (pmol/min/μg). Storage: Store at -70°C. Form: Supplied as a solution containing sodium chloride, sodium acetate, and 20% glycerol. Source: Mouse NSO cells. Species: Human. EC 3.1.1.1; Carboxylesterase 2; CES2; CES2A1; CE-2; PCE-2; iCE. Cat No: NATE-0812. | |
| CART (55-102) (human) | Cocaine- and amphetamine-regulated transcript (CART) is a neuropeptide protein with potent appetite-suppressing activity. It inhibits normal and starvation-induced feeding and blocks the neuropeptide Y-induced feeding response. Synonyms: H-Val-Pro-Ile-Tyr-Glu-Lys-Lys-Tyr-Gly-Gln-Val-Pro-Met-Cys-Asp-Ala-Gly-Glu-Gln-Cys-Ala-Val-Arg-Lys-Gly-Ala-Arg-Ile-Gly-Lys-Leu-Cys-Asp-Cys-Pro-Arg-Gly-Thr-Ser-Cys-Asn-Ser-Phe-Leu-Leu-Lys-Cys-Leu-OH (Disulfide bridge: Cys14-Cys32, Cys20-Cys40, Cys34-Cys47); L-valyl-L-prolyl-L-isoleucyl-L-tyrosyl-L-alpha-glutamyl-L-lysyl-L-lysyl-L-tyrosyl-glycyl-L-glutaminyl-L-valyl-L-prolyl-L-methionyl-L-cysteinyl-L-alpha-aspartyl-L-alanyl-glycyl-L-alpha-glutamyl-L-glutaminyl-L-cysteinyl-L-alanyl-L-valyl-L-arginyl-L-lysyl-glycyl-L-alanyl-L-arginyl-L-isoleucyl-glycyl-L-lysyl-L-leucyl-L-cysteinyl-L-alpha-aspartyl-L-cysteinyl-L-prolyl-L-arginyl-glycyl-L-threonyl-L-seryl-L-cysteinyl-L-asparagyl-L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-lysyl-L-cysteinyl-L-leucine (14->32),(20->40),(34->47)-tris(disulfide). Grades: ≥95%. CAS No. 214050-22-3. Molecular formula: C225H365N65O65S7. Mole weight: 5245.18. | |
| CART (55-102) (rat) | Cocaine- and amphetamine-regulated transcript (CART) is a neuropeptide protein with potent appetite-suppressing activity. It inhibits normal and starvation-induced feeding and blocks the neuropeptide Y-induced feeding response. Uses: Appetite suppressant. Synonyms: H-Ile-Pro-Ile-Tyr-Glu-Lys-Lys-Tyr-Gly-Gln-Val-Pro-Met-Cys-Asp-Ala-Gly-Glu-Gln-Cys-Ala-Val-Arg-Lys-Gly-Ala-Arg-Ile-Gly-Lys-Leu-Cys-Asp-Cys-Pro-Arg-Gly-Thr-Ser-Cys-Asn-Ser-Phe-Leu-Leu-Lys-Cys-Leu-OH (Disulfide bridge: Cys14-Cys32, Cys20-Cys40, Cys34-Cys37); L-isoleucyl-L-prolyl-L-isoleucyl-L-tyrosyl-L-alpha-glutamyl-L-lysyl-L-lysyl-L-tyrosyl-glycyl-L-glutaminyl-L-valyl-L-prolyl-L-methionyl-L-cysteinyl-L-alpha-aspartyl-L-alanyl-glycyl-L-alpha-glutamyl-L-glutaminyl-L-cysteinyl-L-alanyl-L-valyl-L-arginyl-L-lysyl-glycyl-L-alanyl-L-arginyl-L-isoleucyl-glycyl-L-lysyl-L-leucyl-L-cysteinyl-L-alpha-aspartyl-L-cysteinyl-L-prolyl-L-arginyl-glycyl-L-threonyl-L-seryl-L-cysteinyl-L-asparagyl-L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-lysyl-L-cysteinyl-L-leucine (14->32),(20->40),(34->47)-tris(disulfide). Grades: ≥95%. CAS No. 209615-79-2. Molecular formula: C226H367N65O65S7. Mole weight: 5259.21. | |
| CART (62-76) (rat, human) | Cocaine- and amphetamine-regulated transcript (CART) is a neuropeptide protein with potent appetite-suppressing activity. It inhibits normal and starvation-induced feeding and blocks the neuropeptide Y-induced feeding response. Synonyms: H-Tyr-Gly-Gln-Val-Pro-Met-Cys-Asp-Ala-Gly-Glu-Gln-Cys-Ala-Val-OH; L-tyrosyl-glycyl-L-glutaminyl-L-valyl-L-prolyl-L-methionyl-L-cysteinyl-L-alpha-aspartyl-L-alanyl-glycyl-L-alpha-glutamyl-L-glutaminyl-L-cysteinyl-L-alanyl-L-valine; Cocaine and amphetamine-regulated transcript (62-76) (rat, human). Grades: ≥90%. CAS No. 210978-19-1. Molecular formula: C64H99N17O23S3. Mole weight: 1570.77. | |
| CGP7930 | CGP7930 is a positive allosteric modulator at the GABAB receptor. It has anxiolytic effects in animal studies, and has a synergistic effect with GABAB agonists such as baclofen and GHB. It increases the potency and efficacy of GABA at both native and recombinant GABAB receptors with EC50 values of 5.37 and 4.60μM respectively. It also enhances the inhibitory effect of the agonist L-baclofen in cultured cortical neurons. It reduces operant self-administration of ethanol and cocaine in rats. Uses: Cgp7930 has anxiolytic effects in animal studies, and has a synergistic effect with gabab agonists such as baclofen and ghb. it reduces operant self-administration of ethanol and cocaine in rats. Synonyms: 3,5-Bis(1,1-dimethylethyl)-4-hydroxy-beta,beta-dimethylbenzenepropanol;2,6-Ditert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol;3-(3',5'-Di-tert-butyl-4'-hydroxy)phenyl-2,2-dimethylpropanol;CGP7930; CGP-7930; CGP 7930. Grades: >98 %. CAS No. 57717-80-3. Molecular formula: C19H32O2. Mole weight: 292.46. | |
| cis-Flupenthixol hydrochloride | cis-Flupenthixol is a typical antipsychotic, a dopamine D2 receptor antagonist, and an inverse agonist at the serotonin (5-HT) receptor subtype 5-HT2A. In vivo, cis-flupenthixol reduces cocaine-induced locomotor activity and prevents development of conditioned place preferences for the immediate effects of intravenously administered cocaine without affecting development of conditioned place aversions in rats. It is also a neuroleptic agent related structurally to thiothixene. Uses: Antipsychotic agents. Synonyms: cis-Flupentixol; cis-(Z)-Flupentixol dihydrochloride; 2-[4-[(3Z)-3-[2-(trifluoromethyl)thioxanthen-9-ylidene]propyl]piperazin-1-yl]ethanol dihydrochloride; Emergil. Grades: ≥95%. CAS No. 51529-01-2. Molecular formula: C23H25F3N2OS·2HCl. Mole weight: 507.4. | |
| CVT10216 | CVT10216 is a potent and selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) with IC50 value of 29nM, thereby inhibiting dopamine synthesis. It is active in suppressing alcohol and cocaine use, and anxiety. It has been shown to produce anxiolytic effects in four different rodent models, including a model of repeated alcohol withdrawal-induced anxiety. It increases acetaldehyde after alcohol gavage and inhibits 2-bottle choice alcohol intake in heavy drinking rodents. It prevents operant self-administration and eliminates cue-induced reinstatement of alcohol seeking. It also prevents alcohol-induced increases in NAc DA without changing basal levels. Uses: Cvt10216 is active in suppressing alcohol and cocaine use, and anxiety. Synonyms: CVT-10216; CVT 10216; CVT10216. 3-[[[3-[4-[(Methylsulfonyl)amino]phenyl]-4-oxo-4H-chromen-7-yl]oxy]methyl]benzoic acid;GS 455534. Grades: >98 %. CAS No. 1005334-57-5. Molecular formula: C24H19NO7S. Mole weight: 465.48. | |
| Cyclotraxin B | Cyclotraxin B is a selective and potent Trk B (BDNF/NT-3) receptor inhibitor with an IC50 value of 0.30 nM. It prevents receptor activation by BDNF without interfering with BDNF binding. It sometimes fused with tat-protein for increased brain permeability in rodent studies. It has been shown to exhibit putative anxiolytic properties in mice. It prevents cold allodynia induced by BDNF in mice and reduces cocaine self-administration. Synonyms: L-Cysteinyl-L-asparaginyl-L-prolyl-L-methionylglycyl-L-tyrosyl-L-threonyl-L-lysyl-L-a-glutamylglycyl-L-cysteine, cyclic (1>11)-disulfide. Grades: >98%. CAS No. 1203586-72-4. Molecular formula: C48H73N13O17S3. Mole weight: 1200.36. | |
| Desipramine-2,4,6,8-d4 Hydrochloride (10,11-Dihydro-N-methyl-5H-dibenz[b,f]azepine-5-propanamine-d4, G-35020-d4, JB-8181-d4, NSc-114901-d4, Norpramin-d4, Nortimil-d4, Pertofran-d4, Pertofrane-d4, Petylyl-d4) | Desipramine is an active metabolite of imipramine and has been found to be useful in the treatment of neuropathic pain. It may also be used to treat symptoms of cocaine withdrawal. Desipramine is a tricyclic antidepressant (TCA). Tricyclic antidepressants contain a characteristic three ringed nucleus structure. They act primarily as serotoninnorepinephri ne reuptake inhibitors. Tricyclic antidepressants are mainly used as antidepressants, but have also been for the treatment of anxiety disorders and attention hyperactivity disorder and as an adjunct to certain analgesics to treat chronic pain. In many treatments they have been replaced by other compounds with fewer sideeffects. Group: Biochemicals. Alternative Names: 10,11-Dihydro-N-methyl-5H-dibenz[b,f]azepine-5-propanamine-d4; G-35020-d4; JB-8181-d4; NSc-114901-d4; Norpramin-d4; Nortimil-d4; Pertofran-d4; Pertofrane-d4; Petylyl-d4. Grades: Highly Purified. CAS No. 61361-34-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Desipramine (Norpramin®, Pertofrane®) (HRP) | Desipramine is an active metabolite of imipramine and has been found to be useful in the treatment of neuropathic pain. It may also be used to treat symptoms of cocaine withdrawal. Desipramine is a tricyclic antidepressant (TCA). Tricyclic antidepressants contain a characteristic three ringed nucleus structure. They act primarily as serotoninnorepinephri ne reuptake inhibitors. Tricyclic antidepressants are mainly used as antidepressants, but have also been for the treatment of anxiety disorders and attention hyperactivity disorder and as an adjunct to certain analgesics to treat chronic pain. In many treatments they have been replaced by other compounds with fewer sideeffects. Group: Biochemicals. Grades: Purified. Pack Sizes: 500ul. US Biological Life Sciences. | Worldwide |
| Dimethocaine | Dimethocaine is a local anesthetic with stimulatory properties that is half the potency of cocaine. Group: Biochemicals. Alternative Names: 2-[(Diethylamino)methyl]-2-methyl-1-propanol 1-(4-Aminobenzoate); 3-(Diethylamino)-2,2-dimethyl-1-propanol 4-Aminobenzoate; p-3-(Diethylamino)-2,2-dimethyl-1-propanol Amino Benzene; 3-(Diethylamino)-2,2-dimethyl-1-Propanol p-Aminobenzoate; Larocaine; NSC 68927; 4-Aminobenzoic Acid 3-Diethylamino-2,2-dimethylpropyl Ester. Grades: Highly Purified. CAS No. 94-15-5. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Dimethocaine Hydrochloride | A local anesthetic with stimulant properties. Studies have shown its potency to be about half that of Cocaine. Group: Biochemicals. Alternative Names: 1-Aminobenzoyl-2,2-dimethyl-3-diethylaminopropanol Hydrochloride; 3-Diethylamino-2,2-dimethylpropyl p-aminobenzoate Hydrochloride; Diethylaminoneopentyl Alcohol Hydrochloride p-Aminobenzoate; Larocaine Hydrochloride. Grades: Highly Purified. CAS No. 553-63-9. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Eplivanserin hemifumarate | Eplivanserin hemifumarate is a potent and selective 5-HT2A antagonist (IC50 = 5.8 and 120 and >100 nM for 5-HT2A, 5-HT2B and 5-HT2C, respectively) with no activity for dopamine, histamine and adrenergic receptors. It attenuates cocaine-induced hyperactivity, increases dopamine (DA) release in rat medial prefrontal cortex (mPFC) and potentiates haloperidol-induced DA release in the mPFC and nucleus accumbens. Synonyms: SR-46349B; SR 46349B; SR46349B; (1Z,2E)-1-(2-Fluorophenyl)-3-(4-hydroxyphenyl)-2-propen-1-one O-[2-(dimethylamino)ethyl]oxime hemifumarate. Grades: ≥98% by HPLC. CAS No. 130580-02-8. Molecular formula: C19H21FN2O2.1/2C4H4O4. Mole weight: 386.42. | |
| Esterase from Bacillus stearothermophilus, Recombinant | An esterase is a hydrolase that splits esters into acids and alcohols. Applications: Esterase, from bacillus stearothermophilus, may be used for the characterization of novel esterases. this product is recombinant and expressed in e. coli. Group: Enzymes. Synonyms: EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyrate esterase; triacetin esterase; carboxyl ester hydrolase; butyrate esterase; methylbutyrase; α-carboxylestera. Enzyme Commission Number: EC 3.1.1.1. CAS No. 9016-18-6. Esterase. Activity: > 8.0 units/mg. Storage: -20°C. Source: E. coli. Species: Bacillus stearothermophilus. EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyrate esterase; triacetin esterase; carboxyl ester hydrolase; butyrate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxylic acid esterase; cocaine esterase; 9016-18-6. Pack: Bottomless glass bottle. Contents are inside inserted fused cone. Cat No: NATE-0241. | |
| Esterase from Bacillus subtilis, Recombinant | An esterase is a hydrolase that splits esters into acids and alcohols. Applications: Esterase, from bacillus subtilis, may be used in protein engineering research as well as to study the kinetic resolution of acetates of arylaliphatic tertiary alcohols. this product is recombinant and expressed in e. coli (> 10 units/mg). Group: Enzymes. Synonyms: EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyrate esterase; triacet. Enzyme Commission Number: EC 3.1.1.1. CAS No. 9016-18-6. Esterase. Activity: Type I, > 10 units/mg; Type II, > 0.8 units/mg. Storage: -20°C. Source: E. coli. Species: Bacillus subtilis. EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyrate esterase; triacetin esterase; carboxyl ester hydrolase; butyrate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxylic acid esterase; cocaine esterase; 9016-18-6. Pack: Bottomless glass bottle. Contents are inside inserted fused cone. Cat No: NATE-0242. | |
| Esterase from Methylobacterium populi, Recombinant | An esterase is a hydrolase that splits esters into acids and alcohols. Applications: Esterases are used for various downstream biotechnological applications. esterase from methylobacterium populi is used to convert 1 μmol of 4-nitrophenyl-l-acetate per minute at ph 7.5 and 30 oc. Group: Enzymes. Synonyms: EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyrate esterase; triacetin esterase; carboxyl ester hydrolase; butyrate esterase; me. Enzyme Commission Number: EC 3.1.1.1. CAS No. 9016-18-6. Esterase. Activity: > 0.5 units/mg. Storage: -20°C. Source: E. coli. Species: Methylobacterium populi. EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyrate esterase; triacetin esterase; carboxyl ester hydrolase; butyrate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxylic acid esterase; cocaine esterase; 9016-18-6. Pack: Bottomless glass bottle. Contents are inside inserted fused cone. Cat No: NATE-0243. | |
| Esterase from Nocardia farcinica, Recombinant | An esterase is a hydrolase that splits esters into acids and alcohols. Applications: Esterase from n ocardia farcinica may be useful to study the positional specificity of ester hydrolysis. Group: Enzymes. Synonyms: EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyRate esterase; triacetin esterase; carboxyl ester hydrolase; butyRate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; es. Enzyme Commission Number: EC 3.1.1.1. CAS No. 9016-18-6. Esterase. Activity: > 0.4 units/mg. Storage: -20°C. Source: E. coli. Species: Nocardia farcinica. EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyRate esterase; triacetin esterase; carboxyl ester hydrolase; butyRate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxylic acid esterase; cocaine esterase; 9016-18-6. Pack: Bottomless glass bottle. Contents are inside inserted fused cone. Cat No: NATE-0244. | |
| Esterase from Paenibacillus barcinonensis, Recombinant | An esterase is a hydrolase that splits esters into acids and alcohols. Applications: Esterase paenibacillus barcinonensis, also known as esta, may be useful in protein engineering studies. it has been engineered to increase enantioselectivity. Group: Enzymes. Synonyms: EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyRate esterase; triacetin esterase; carboxyl ester hydrolase; butyRate esterase; methylbutyrase; α-carboxylest. Enzyme Commission Number: EC 3.1.1.1. CAS No. 9016-18-6. Esterase. Activity: > 12 units/mg. Storage: -20°C. Source: E. coli. Species: Paenibacillus barcinonensis. EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyRate esterase; triacetin esterase; carboxyl ester hydrolase; butyRate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxylic acid esterase; cocaine esterase; 9016-18-6. Pack: Bottomless glass bottle. Contents are inside inserted fused cone. Cat No: NATE-0245. | |
| Esterase from Pelobacter propionicus, Recombinant | An esterase is a hydrolase that splits esters into acids and alcohols. Applications: Esterase pelobacter propionicus, may be useful in the characterization of novel esterases. it has been used to aid the characterization of esterases from arctic sediment. Group: Enzymes. Synonyms: EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyRate esterase; triacetin esterase; carboxyl ester hydrolase; butyRate esterase; methylbutyrase; α-carboxyl. Enzyme Commission Number: EC 3.1.1.1. CAS No. 9016-18-6. Esterase. Activity: > 0.5 units/mg. Storage: -20°C. Source: E. coli. Species: Pelobacter propionicus. EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyRate esterase; triacetin esterase; carboxyl ester hydrolase; butyRate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxylic acid esterase; cocaine esterase; 9016-18-6. Pack: Bottomless glass bottle. Contents are inside inserted fused cone. Cat No: NATE-0246. | |
| Esterase from Pseudomonas fluorescens, Recombinant | An esterase is a hydrolase that splits esters into acids and alcohols. Applications: The compound is commonly used for the synthesis of biodiesel and biopolymers, as well as in the production of pharmaceuticals, agr ochemicals and flavor compounds. Group: Enzymes. Synonyms: EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyRate esterase; triacetin esterase; carboxyl ester hydrolase; butyRate esterase; methyl. Enzyme Commission Number: EC 3.1.1.1. CAS No. 9016-18-6. Esterase. Activity: Type I, > 4 units/mg; Type II, > 0.3 units/mg. Storage: -20°C. Source: E. coli. Species: Pseudomonas fluorescens. EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyRate esterase; triacetin esterase; carboxyl ester hydrolase; butyRate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxylic acid esterase; cocaine esterase; 9016-18-6. Pack: Bottomless glass bottle. Contents are inside inserted fused cone. Cat No: NATE-0247. | |
| Esterase from Pyrobaculum calidifontis, Recombinant | An esterase is a hydrolase that splits esters into acids and alcohols. Applications: Esterase, from pyrobaculum calidifontis, may be used in structural biology research. Group: Enzymes. Synonyms: EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyRate esterase; triacetin esterase; carboxyl ester hydrolase; butyRate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B. Enzyme Commission Number: EC 3.1.1.1. CAS No. 9016-18-6. Esterase. Activity: > 2.0 units/mg. Storage: -20°C. Source: E. coli. Species: Pyrobaculum calidifontis. EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyRate esterase; triacetin esterase; carboxyl ester hydrolase; butyRate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxylic acid esterase; cocaine esterase; 9016-18-6. Pack: Bottomless glass bottle. Contents are inside inserted fused cone. Cat No: NATE-0248. | |
| Esterase Isoenzyme 1 from Porcine liver, Recombinant | An esterase is a hydrolase that splits esters into acids and alcohols. Applications: Esterase isoenzymes may be used to identify the mon ocytic element in normal and leukemic cells. they may be used for the bi ochemical characterization of different hematopoietic cell lineages and stages of differentiation when studying leukemias and lymphomas. esterase isoenzyme is recombinant and from porcine liver. it is expressed in e. coli. Group: Enzymes. Synonyms: EC 3.1.1.1; Esterase Isoenzyme 1; 9016-18-6; carboxylesterase; ali-esterase; B-esterase; monobutyrase; cocaine esteras. Enzyme Commission Number: EC 3.1.1.1. CAS No. 9016-18-6. Esterase. Activity: > 30.0 U/g. Storage: -20°C. Source: E. coli. Species: Porcine liver. EC 3.1.1.1; Esterase Isoenzyme 1; 9016-18-6; carboxylesterase; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyrate esterase; triacetin esterase; carboxyl ester hydrolase; butyrate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxylic acid esterase; cocaine esterase. Pack: Bottomless glass bottle. Contents are inside inserted fused cone. Cat No: NATE-0229. | |
| Esterase Isoenzyme 2 from Porcine liver, Recombinant | An esterase is a hydrolase that splits esters into acids and alcohols. Applications: Esterase isoenzymes may be used to identify the mon ocytic element in normal and leukemic cells. they may be used for the bi ochemical characterization of different hematopoietic cell lineages and stages of differentiation when studying leukemias and lymphomas. esterase isoenzyme 2, is from porcine liver and is recombinant and expressed in e. coli. Group: Enzymes. Synonyms: EC 3.1.1.1; Esterase Isoenzyme 2; 9016-18-6; carboxylesterase; ali-esterase; B-esterase; monobutyrase; cocaine estera. Enzyme Commission Number: EC 3.1.1.1. CAS No. 9016-18-6. Esterase. Activity: > 80 U/g. Storage: -20°C. Source: E. coli. Species: Porcine liver. EC 3.1.1.1; Esterase Isoenzyme 2; 9016-18-6; carboxylesterase; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyrate esterase; triacetin esterase; carboxyl ester hydrolase; butyrate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxylic acid esterase; cocaine esterase. Pack: Bottomless glass bottle. Contents are inside inserted fused cone. Cat No: NATE-0230. | |
| Esterase Isoenzyme 3 from Porcine liver, Recombinant | An esterase is a hydrolase that splits esters into acids and alcohols. Applications: Esterase isoenzymes may be used to identify the mon ocytic element in normal and leukemic cells. they may be used for the biochemical characterization of different hematopoietic cell lineages and stages of differentiation when studying leukemias and lymphomas. Group: Enzymes. Synonyms: EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase. Enzyme Commission Number: EC 3.1.1.1. CAS No. 9016-18-6. Esterase. Activity: > 0.8 units/mg. Storage: -20°C. Source: E. coli. Species: Porcine liver. EC 3.1.1.1; Esterase Isoenzyme 3; 9016-18-6; carboxylesterase; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyrate esterase; triacetin esterase; carboxyl ester hydrolase; butyrate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxylic acid esterase; cocaine esterase. Pack: Bottomless glass bottle. Contents are inside inserted fused cone. Cat No: NATE-0231. | |
| Esterase Isoenzyme 5 from Porcine liver, Recombinant | An esterase is a hydrolase that splits esters into acids and alcohols. Applications: Esterase isoenzymes may be used to identify the mon ocytic element in normal and leukemic cells. they may be used for the bi ochemical characterization of different hematopoietic cell lineages and stages of differentiation when studying leukemias and lymphomas. esterase isoenzyme 5 is recombinant and from porcine liver. it is expressed in e. coli. Group: Enzymes. Synonyms: EC 3.1.1.1; Esterase Isoenzyme 5; 9016-18-6; carboxylesterase; ali-esterase; B-esterase; monobutyrase; cocaine e. Enzyme Commission Number: EC 3.1.1.1. CAS No. 9016-18-6. Esterase. Activity: > 0.5 units/mg. Storage: -20°C. Source: E. coli. Species: Porcine liver. EC 3.1.1.1; Esterase Isoenzyme 5; 9016-18-6; carboxylesterase; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyrate esterase; triacetin esterase; carboxyl ester hydrolase; butyrate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxylic acid esterase; cocaine esterase. Pack: Bottomless glass bottle. Contents are inside inserted fused cone. Cat No: NATE-0232. | |
| Esterase Isoenzyme 6 from Porcine liver, Recombinant | An esterase is a hydrolase that splits esters into acids and alcohols. Applications: Esterase isoenzymes may be used to identify the mon ocytic element in normal and leukemic cells. they may be used for the bi ochemical characterization of different hematopoietic cell lineages and stages of differentiation when studying leukemias and lymphomas. esterase isoenzyme 6 is recombinant and from porcine liver. it is expressed in e. coli. Group: Enzymes. Synonyms: EC 3.1.1.1; Esterase Isoenzyme 6; 9016-18-6; carboxylesterase; ali-esterase; B-esterase; monobutyrase; cocaine e. Enzyme Commission Number: EC 3.1.1.1. CAS No. 9016-18-6. Esterase. Activity: > 1.2 units/mg. Storage: -20°C. Source: E. coli. Species: Porcine liver. EC 3.1.1.1; Esterase Isoenzyme 6; 9016-18-6; carboxylesterase; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyrate esterase; triacetin esterase; carboxyl ester hydrolase; butyrate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxylic acid esterase; cocaine esterase. Pack: Bottomless glass bottle. Contents are inside inserted fused cone. Cat No: NATE-0233. | |
| GR 127935 Hydrochloride (5-HT1B/1D Serotonin Receptor Antagonist, GR 127935 Hydrochloride, GR-127935 Hydrochloride, GR127935 Hydrochloride) | A selective 5-HT1B/1D receptor antagonist. Selectivity was found to be similar for B (pki = 9.2-9.8) and D (pki = 8.6-9.1) receptor types. GR 127935 works well in vivo and was shown to block (+)-MDMA-induced hyperactivity in rats. It alters release of serotonin in the brain, as well as reducing drug-seeking behavior in cocaine addicted rats. In transformed rat C5 glioma cells, this inhibitor blocked 5HT with an IC50 = 97pM. Group: Biochemicals. Grades: Highly Purified. CAS No. 148642-42-6. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?·HCl. US Biological Life Sciences. | Worldwide |
| GS 39783 | GS 39783 is an allosteric positive modulator of GABAB receptors, decreases cocaine self-administration, blocks the rewarding properties of nicotine and produces anxiolytic-like activity without the side effects associated with baclofen or benzodiazepines. Uses: Positive allosteric modulator of gabab receptor function. Synonyms: GS39783; GS-39783; GS 39783; N,N'-Dicyclopentyl-2-(methylthio)-5-nitro-4,6-pyrimidinediamine;4-N,6-N-dicyclopentyl-2-methylsulfanyl-5-nitropyrimidine-4,6-diamine. Grades: ≥98%. CAS No. 39069-52-8. Molecular formula: C15H23N5O2S. Mole weight: 337.44. | |
| GYKI-52466 | GYKI-52466 is a non-competitive AMPA receptor antagonist. It belongs to 2,3-benzodiazepine that acts as an ionotropic glutamate receptor antagonist. It has anticonvulsant and neuroprotective properties. It is an orally-active anticonvulsant and skeletal muscle relaxant. It also was found to have therapeutic potential for cocaine addiction treatment. Uses: Gyki-52466 is an orally-active anticonvulsant and skeletal muscle relaxant. it also was found to have therapeutic potential for cocaine addiction treatment. Synonyms: 4-(8-Methyl-9H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl)aniline;GYKI-52466; GYKI52466; GYKI 52466; GYKI-5,2466; GYKI52,466; GYKI 52,466. Grades: >99 %. CAS No. 102771-26-6. Molecular formula: C17H15N3O2. Mole weight: 293.33. | |
| Hypoxanthine-13C2,15N | A metabolite of Purine in cocaine addiction. Group: Biochemicals. Alternative Names: 1,9-Dihydro-. Grades: Highly Purified. CAS No. 1246820-04-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Immobilized Lipozyme from Mucor miehei | Lipases catalyze the hydrolysis of triacylglycerols into glycerol and free fatty acids. Applications: Lipases are used industrially for the resolution of chiral compounds and the transesterification production of biodiesel. Group: Enzymes. Synonyms: Lipozyme; carboxylesterase; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyRate esterase; triacetin esterase; carboxyl ester hydrolase; butyRate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A. Enzyme Commission Number: EC 3.1.1.1. CAS No. 9016-18-6. Esterase. Activity: >30 U/g. Storage: 2-8°C. Form: granular; brown. Source: Mucor miehei. Lipozyme; carboxylesterase; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyRate esterase; triacetin esterase; carboxyl ester hydrolase; butyRate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxylic acid esterase; cocaine esterase; EC 3.1.1.1. Cat No: NATE-0408. | |
| JDTic dihydrochloride | JDTic dihydrochloride is a highly selective antagonist for the κ-opioid receptor with IC50 value of 0.02nM without affecting the μ- or δ-opioid receptors. It is a 4-phenylpiperidine derivative and distantly structurally related to analgesic drugs such as meperidine and ketobemidone and more closely to the mu opioid antagonist alvimopan. It is structurally distinct from other kappa antagonists such as norbinaltorphimine. It is more selective and potent for KOR activity than other KOR antagonists. It is shown to block the antinociceptive response of nicotine in the tail-flick test with a dose-dependent manner. It can also block the nicotine withdrawal signs in mice vi... it can also block the nicotine withdrawal signs in mice via effecting the expression of a cpa associated with nicotine withdrawal. it is also reported to decrease the number of somatic withdrawal signs in morphine-dependent rats. it may produce antidepressant and anxiolytic effects and may be used in the treatment of addiction to cocaine and morphine. Synonyms: JDTic (2HCl);(3R)-1,2,3,4-Tetrahydro-7-hydroxy-N-[(1S)-1-[[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-2-methylpropyl]-3-isoquinolinecarboxamide hydrochloride;(R)-7-hydroxy-N-((S)-1-((3R,4R)-4-(3-hydroxyphenyl)-3,4- . Grades: 95%. CAS No. 785835-79-2. Molecular formula: C28H41Cl2N3O3. Mole weight: 538.55. | |
| JHW 007 hydrochloride | The hydrochloride salt form of JHW 007, which is a dopamine uptake inhibitor and could also restrain the effects of cocaine in a dose-dependent manner. Synonyms: JHW 007 hydrochloride; JHW007 hydrochloride; JHW-007 hydrochloride; (3-endo)-3-[Bis(4-fluorophenyl)methoxy]-8-butyl-8-azabicyclo[3.2.1]octane hydrochloride. Grades: ≥99% by HPLC. CAS No. 202645-74-7. Molecular formula: C24H29F2NO.HCl. Mole weight: 421.95. | |
| LY 379268 | LY 379268 is a group II mGlu receptor agonist with EC50 values of 2.69 and 4.48 nM for hmGlu2 and hmGlu3. Some research shows that LY379268 can attenuate cocaine-induced increases in DA in nonhuman primates. Synonyms: LY379268; LY 379268; LY-379268; (1R,4R,5S,6R)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid. Grades: ≥99% by HPLC. CAS No. 191471-52-0. Molecular formula: C7H9NO5. Mole weight: 187.15. | |
| LY 379268 disodium salt | Sodium salt of LY 379268. LY 379268 is a group II mGlu receptor agonist with EC50 values of 2.69 and 4.48 nM for hmGlu2 and hmGlu3. Some research shows that LY379268 can attenuate cocaine-induced increases in DA in nonhuman primates. Synonyms: LY 379268 disodium salt; LY379268 disodium salt; LY-379268 disodium salt; (1R,4R,5S,6R)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid disodium salt. Grades: ≥98% by HPLC. Molecular formula: C7H7NNa2O5. Mole weight: 231.11. | |
| Methyl 2-Methylnicotinate | Methyl 2-Methylnicotinate is an ester derivative of nicotinic acid used in the preparation of bicyclic nitrogen containing heterocycles. Methyl 2-Methylnicotinate is a pyrolysis product of cocaine. Group: Biochemicals. Alternative Names: 2-Methyl-3-pyridinecarboxylic Acid Methyl Ester; Methyl 2-Methyl-3-pyridinecarboxylate; 2-Methylnicotinic Acid Methyl Ester. Grades: Highly Purified. CAS No. 65719-09-7. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
| methylecgonone reductase | The enzyme from the plant Erythroxylum coca catalyses the penultimate step in the biosynthesis of cocaine. In vivo the reaction proceeds in the opposite direction. With NADH instead of NADPH the reaction rate is reduced to 14%. The enzyme also reduces tropinone, nortropinone and 6-hydroxytropinone but with lower reaction rates. Group: Enzymes. Synonyms: MecgoR (gene name). Enzyme Commission Number: EC 1.1.1.334. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0248; methylecgonone reductase; EC 1.1.1.334; MecgoR (gene name). Cat No: EXWM-0248. | |
| MFZ 10-7 | MFZ 10-7 is a mGlu5 receptor negative allosteric modulator. It can inhibit mGlu5 glutamate-mediated calcium mobilization with IC50 value of 1.22 nM. MFZ 10-7 can inhibit cocaine-taking and cocaine-seeking behavior in rats. Synonyms: 3-Fluoro-5-[2-(6-methyl-2-pyridinyl)ethynyl]benzonitrile hydrochloride. Grades: ≥99% by HPLC. CAS No. 1224431-15-5. Molecular formula: C15H9FN2.HCl. Mole weight: 272.7. | |
| m-Hydroxybenzoylecgonine | analytical standard. Group: Cocaine analogs standards. | |
| MMPIP (6-(4-Methoxyphenyl)-5-methyl-3-(4-pyridinyl)-isoxazolo[ 4,5-c]pyridin-4(5H)-one) | A potent negative allosteric modulator highly selective for mGlu7 receptors (IC50 = 15nM). No effect on other subtype mGlu receptors. Frequently used in studies of alcohol and cocaine addition, depression, anxiety and stress related disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 479077-02-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Native Bacillus stearothermophilus Esterase | An esterase is a hydrolase that splits esters into acids and alcohols. Applications: The compound is commonly used for the synthesis of biodiesel and biopolymers, as well as in the production of pharmaceuticals, agr ochemicals and flavor compounds. Group: Enzymes. Synonyms: EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyRate esterase; triacetin esterase; carboxyl ester hydrolase; butyRate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; se. Enzyme Commission Number: EC 3.1.1.1. CAS No. 9016-18-6. Esterase. Activity: > 0.2 units/mg. Storage: 2-8°C. Source: Bacillus stearothermophilus. EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyRate esterase; triacetin esterase; carboxyl ester hydrolase; butyRate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxylic acid esterase; cocaine esterase; 9016-18-6. Cat No: NATE-0234. | |
| Native Bacillus thermoglucosidasius Esterase | An esterase is a hydrolase that splits esters into acids and alcohols. Group: Enzymes. Synonyms: EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyRate esterase; triacetin esterase; carboxyl ester hydrolase; butyRate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxylic acid esterase; cocaine esterase; 9016-18-6. Enzyme Commission Number: EC 3.1.1.1. CAS No. 9016-18-6. Esterase. Activity: ~0.1 units/mg. Storage: 2-8°C. Form: lyophilized powder. Source: Bacillus thermoglucosidasius. EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyRate esterase; triacetin esterase; carboxyl ester hydrolase; butyRate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxylic acid esterase; cocaine esterase; 9016-18-6. Cat No: NATE-0235. | |
| Native Horse Esterase | An esterase is a hydrolase that splits esters into acids and alcohols. Group: Enzymes. Synonyms: EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyRate esterase; triacetin esterase; carboxyl ester hydrolase; butyRate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxylic acid esterase; cocaine esterase; 9016-18-6. Enzyme Commission Number: EC 3.1.1.1. CAS No. 9016-18-6. Esterase. Mole weight: Mr ~70 kDa. Activity: 0.5-1.0 units/mg. Storage: -20°C. Form: lyophilized powder; brown. Source: Horse liver. Species: Horse. EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyRate esterase; triacetin esterase; carboxyl ester hydrolase; butyRate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxylic acid esterase; cocaine esterase; 9016-18-6. Cat No: NATE-0236. | |
| Native Porcine Esterase | An esterase is a hydrolase that splits esters into acids and alcohols. Applications: Porcine liver esterase is used to catalyze the hydrolysis of pentaacetyl catechin and epicatechin for use in pharmaceutical and industrial applications. pig liver esterase is commonly used for kinetic resolutions and assymetric synthesis in organic chemistry. esterase from porcine liver has been used in a study to assess the effect of 5-aminolaevulinic acid peptide prodrugs on photosensitization for photodynamic therapy. esterase from porcine liver has also been used in a study to investigate how site-specific atherogenic gene expression correlates with subsequent variable lesion development in c...ms: EC 3.1.1.1; ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase; carboxylate esterase; carboxylic esterase; methylbutyRate esterase; triacetin esterase; carboxyl ester hydrolase; butyRate esterase; methylbutyrase; α-carboxylesterase; propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A; serine esterase; carboxylic acid esterase; cocaine esterase; 9016-18-6. Enzyme Commission Number: EC 3.1.1.1. CAS No. 9016-18-6. Esterase. Activity: Type I, > 15 units/mg solid; Type II, > 50 units/mg; Type III, > 150 units/mg protein (biuret). Storage: -20°C. For | |
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