Combretastatin A4 Suppliers USA
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Product | Description | |
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Combretastatin A4 Quick inquiry Where to buy Suppliers range | ≥98% (HPLC), powder. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy; Enzyme Activators, Inhibitors & Substrates. CAS No. 117048-59-6. Pack Sizes: 5MG, 25MG. IUPAC Name: 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol. Molecular formula: C18H20O5. Mole weight: 316.35. Catalog: APS117048596. Assay: ≥98% (HPLC). SMILES: COc1ccc (\C=C/c2cc (OC)c (OC)c (OC)c2)cc1O. Format: Neat. | |
Combretastatin A4 Quick inquiry Where to buy Suppliers range | Combretastatin A4. Group: Biochemicals. Grades: Purified. CAS No. 117048-59-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
Combretastatin A4 phosphate disodium salt Quick inquiry Where to buy Suppliers range | Combretastatin A4 phosphate disodium salt. Group: Biochemicals. Alternative Names: 2-Methoxy-5-[ (1Z) -2- (3, 4, 5-trimethoxyphenyl) ethenyl]phenol 1-(dihydrogen phosphate) sodium salt; CA 4P. Grades: Highly Purified. CAS No. 168555-66-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C18H19Na2O8P. US Biological Life Sciences. | Worldwide |
Combretastatin A-4 ( (Z) -2-Methoxy-5-[2- (3, 4, 5-trimethoxyphenyl) ethenyl]phenol, 3,4,5-Trimethoxy-3-hydroxy-4-methoxy-(Z)-stilbene, CS-A4) Quick inquiry Where to buy Suppliers range | Combretastatin is a small organic molecule found in the bark of the African bush willow tree Combretum caffrum. Combretastatin-A4 Prodrug Inducer. Group: Biochemicals. Alternative Names: (Z) -2-Methoxy-5-[2- (3, 4, 5-trimethoxyphenyl) ethenyl]phenol, 3,4,5-Trimethoxy-3-hydroxy-4-methoxy-(Z)-stilbene, CS-A4. Grades: Highly Purified. CAS No. 117048-59-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Combretastatin A-4 Phosphate, Disodium Salt (CA 4P) Quick inquiry Where to buy Suppliers range | Phosphorylated, Combretastatin a small organic molecule found in the bark of the African bush willow tree Combretum caffrum. Combretastatin-A4 Prodrug Indu. Group: Biochemicals. Alternative Names: CA 4P. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Fosbretabulin Quick inquiry Where to buy Suppliers range | Fosbretabulin, also called as CA4P, has antitumor activity against anaplastic thyroid cancer (ATC) cell lines. Fosbretabulin, a novel water-soluble vascular-disrupting agent, is a phosphate derivative of a natural stilbenoid phenol derived from the African bush willow (Combretum caffrum). Synonyms: [2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] dihydrogen phosphate; 3,4,5-trimethoxy-3'-hydroxy-4'-methoxystilbene; CA4DP; combretastatin A-4; 168555-66-6 (fosbretabulin disodium); 82855-09-2 (combretastatin); 117048 -59-6 (combretastatin A4). Grades: >98%. CAS No. 222030-63-9. Molecular formula: C18H21O8P. Mole weight: 396.33. | |
Fosbretabulin disodium Quick inquiry Where to buy Suppliers range | Fosbretabulin disodium is the disodium salt of a water-soluble phosphate derivative of a natural stilbenoid phenol derived from the African bush willow (Combretum caffrum) with potential vascular disrupting and antineoplastic activities. Upon administration, the prodrug fosbretabulin is dephosphorylated to its active metabolite, the microtubule-depolymerizing agent combretastatin A4, which binds to tubulin dimers and prevents microtubule polymerization, resulting in mitotic arrest and apoptosis in endothelial cells. In addition, this agent disrupts the engagement of the endothelial cell-specific junctional molecule vascular endothelial-cadherin (VE-cadherin) and so the activity of the VE-cadherin/β-catenin/Akt signaling pathway, which may result in the inhibition of endothelial cell migration and capillary tube formation. As a result of fosbretabulin's dual mechanism of action, the tumor vasculature collapses, resulting in reduced tumor blood flow and ischemic necrosis of tumor tissue. Synonyms: Combretastatin A-4 phosphate disodium, CA4P; CA4DP; Combretastatin A-4 phosphate. CAS No. 168555-66-6. Molecular formula: C18H19Na2O8P. Mole weight: 440.295. | |
Ombrabulin Quick inquiry Where to buy Suppliers range | Ombrabulin is a synthetic water-soluble analogue of combretastatin A4, derived from the South African willow bush (Combretum caffrum), with potential vascular-disrupting and antineoplastic activities. Ombrabulin binds to the colchicine binding site of endothelial cell tubulin, inhibiting tubulin polymerization and inducing mitotic arrest and apoptosis in endothelial cells. Synonyms: AVE8062; AVE 8062; AC-7700; AC 7700; AC7700; CS-39-L-Ser.HCl; AVE-8062A; AVE-8062; RPR-258062A; RPR 258062A. CAS No. 181816-48-8. Molecular formula: C21H26N2O6. Mole weight: 402.45. |