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| Product | Description | |
|---|---|---|
| Concanamycin C | It is produced by the strain of Streptomyces diastatochromogenes. It has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase, which is an important tool for biochemical research. Synonyms: (3Z, 5E, 7R, 8R, 9S, 10S, 11R, 13E, 15E, 17S, 18R)-18-[(1S, 2R, 3S)-3-[(2R, 4R, 5S, 6R)-4-[(2, 6-Dideoxy-β-D-arabino-hexopyranosyl)oxy]tetrahydro-2-hydroxy-5-methyl-6-(1E)-1-propen-1-yl-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-9-ethyl-8, 10-dihydroxy-3, 17-dimethoxy-5, 7, 11, 13-tetramethyloxacyclooctadeca-3, 5, 13, 15-tetraen-2-one; 4'-O-de(aminocarbonyl)-Concanamycin A. Grades: ≥98%. CAS No. 81552-34-3. Molecular formula: C45H74O13. Mole weight: 823.06. |  |
| Concanamycin C (4'-O-De (aminocarbonyl) concanamycin A) (High Purity) | Antibiotic. Vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Anti-osteoporotic. Antiviral. Immunosuppressive. Antifungal and anti-yeast. Group: Biochemicals. Grades: Highly Purified. CAS No. 81552-34-3. Pack Sizes: 25ug, 100ug, 500ug. US Biological Life Sciences. |  Worldwide |
| Concanamycin a | Concanamycin A (Folimycin; Antibiotic X 4357B) is a macrolide antibiotic, a vacuolar type H+-ATPase (V-ATPase) inhibitor. Concanamycin A is also an inhibitor of lysosomal acidification, can be used to T cell-mediated inflammation research-. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 80890-47-7. Molecular formula: C46H75NO14. Mole weight: 866.09. Purity: >90 %. Product ID: ACM80890477. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Concanamycin A | ?70% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Concanamycin A | Concanamycin A (Folimycin; Antibiotic X 4357B) is a macrolide antibiotic , a vacuolar type H + -ATPase (V-ATPase) inhibitor. Concanamycin A is also an inhibitor of lysosomal acidification, can be used to T cell-mediated inflammation research [1] - [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Antibiotic X 4357B; Folimycin; X 4357B. CAS No. 80890-47-7. Pack Sizes: 25 μg; 50 μg. Product ID: HY-N1724. |  |
| Concanamycin A | It is produced by the strain of Streptomyces diastatochromogenes. It has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase (Ki=0.02 nmol/L), which is an important tool for biochemical research. Synonyms: Folimycin; concanamycin a; Antibiotic X 4357 B; Antibiotic S-45A; X 4357B; (3Z, 5E, 7R, 8R, 9S, 10S, 11R, 13E, 15E, 17S, 18R)-18-[(1S, 2R, 3S)-3-[(2R, 4R, 5S, 6R)-4-[[4-O-(Aminocarbonyl)-2, 6-dideoxy-β-D-arabino-hexopyranosyl]oxy]tetrahydro-2-hydroxy-5-methyl-6-(1E)-1-propen-1-yl-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-9-ethyl-8, 10-dihydroxy-3, 17-dimethoxy-5, 7, 11, 13-tetramethyloxacyclooctadeca-3, 5, 13, 15-tetraen-2-one. Grades: >99% by HPLC. CAS No. 80890-47-7. Molecular formula: C46H75NO14. Mole weight: 866.09. | |
| Concanamycin A (Folimycin, Antibiotic TAN 1323B) | Concanamycin A is the major analogue of the concanamycin complex produced by Streptomyces sp. It has has been shown to act as a potent and specific vacuolar-APTase inhibitor. Concanamycin A inhibits the acidification of organelles and blocks cell surface expression of viral envelope glycoproteins without affecting their synthesis. It also interferes with intracellular protein trafficking and inhibits perforin- and Fas-based lytic pathways in cell-mediated cytotoxicity. Concanamycins are structurally related to the bafilomycins. Group: Biochemicals. Alternative Names: Folimycin, Antibiotic TAN 1323B. Grades: Highly Purified. CAS No. 80890-47-7. Pack Sizes: 250ug. US Biological Life Sciences. | Worldwide |
| Concanamycin A (Olimycin, Antibiotic TAN 1323B, Antibiotic X4357B) (High Purity) | Antibiotic. More potent and specific H+-ATPase inhibitor than bafilomycin A1. Inhibits acidification of organelles such as lysosomes and the Golgi apparatus. Blocks cell surface expression of viral glycoproteins without affecting their synthesis. Cytotoxic in a number of cell lines in a cell viability assay. Induces nitric oxide (NO) production. Autophagy inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 80890-47-7. Pack Sizes: 25ug, 100ug, 1mg. US Biological Life Sciences. | Worldwide |
| Concanamycin B | It is produced by the strain of Streptomyces diastatochromogenes. It has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase, which is an important tool for biochemical research. Synonyms: (3Z, 5E, 7R, 8R, 9S, 10S, 11R, 13E, 15E, 17S, 18R)-18-[(1S, 2R, 3S)-3-[(2R, 4R, 5S, 6R)-4-[[4-O-(Aminocarbonyl)-2, 6-dideoxy-β-D-arabino-hexopyranosyl]oxy]tetrahydro-2-hydroxy-5-methyl-6-(1E)-1-propenyl-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-8, 10-dihydroxy-3, 17-dimethoxy-5, 7, 9, 11, 13-pentamethyloxacyclooctadeca-3, 5, 13, 15-tetraen-2-one; MCH 210; 8-Deethyl-8-methylconcanamycin A. Grades: >95% by HPLC. CAS No. 81552-33-2. Molecular formula: C45H73NO14. Mole weight: 852.06. | |
| Concanamycin B (High Purity) (8-Deethyl-8-methylconcanamycin A) | Antibiotic. Exhibits similar activity as concanamycin A and concanamycin C. Specific vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Suppresses bone resorption. Inhibits proliferation of mouse splenic lymphocytes. Antifungal and larvicidal. Group: Biochemicals. Grades: Highly Purified. CAS No. 81552-33-2. Pack Sizes: 25ug, 100ug, 500ug. US Biological Life Sciences. | Worldwide |
| Concanamycin D | It is produced by the strain of Streptomyces diastatochromogenes. It has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase, which is an important tool for biochemical research. Synonyms: (3E,5Z,13Z,15Z)-18-[4-[4-[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-2-hydroxy-5-methyl-6-[(E)-prop-1-enyl]oxan-2-yl]-3-hydroxypentan-2-yl]-8,10-dihydroxy-3,17-dimethoxy-5,7,9,11,13-pentamethyl-1-oxacyclooctadeca-3,5,13,15-tetraen-2-one; 4'-O-de(aminocarbonyl)-8-deethyl-8-methyl-Concanamycin A. CAS No. 144450-34-0. Molecular formula: C44H72O13. Mole weight: 809.03. | |
| Concanamycin E | It is produced by the strain of Streptomyces diastatochromogenes. It has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase, which is an important tool for biochemical research. Synonyms: Concanamycin A, 8-deethyl-; [6-[2-[4-[(4E,6E,14E,16Z)-10,12-dihydroxy-3,17-dimethoxy-7,9,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6,14,16-tetraen-2-yl]-3-hydroxypentan-2-yl]-2-hydroxy-5-methyl-6-[(E)-prop-1-enyl]oxan-4-yl]oxy-4-hydroxy-2-methyloxan-3-yl] carbamate. CAS No. 144450-35-1. Molecular formula: C44H71NO14. Mole weight: 838.03. | |
| Concanamycin F | It is produced by the strain of Streptomyces diastatochromogenes. It has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase, which is an important tool for biochemical research. Synonyms: Concanamycin A, 23-O-de(4-O-(aminocarbonyl)-2,6-dideoxy-beta-D-arabino-hexopyranosyl)-; concanolide A. CAS No. 144539-92-4. Molecular formula: C39H64O10. Mole weight: 692.92. | |
| Concanamycin G | It is produced by the strain of Streptomyces diastatochromogenes. It has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase, which is an important tool for biochemical research. CAS No. 144730-82-5. Molecular formula: C38H60O9. Mole weight: 660.88. | |
| Bafilomycin A1 (NSC381866) | Bafilomycin A1 is a member of a potent family of macrocyclic lactones with a broad spectrum of biological activity including activity against bacteria, yeast, fungi, nematodes, insects and antitumor cell lines. Bafilomycin A1 is an inhibitor of vacuolar-type ATPase. Related to: Bafilomycin B1, Bafilomycin C1, Concanamycin A.Source:Streptomyces griseus. Group: Biochemicals. Alternative Names: 21-O-De(3-carboxy-1-oxo-2-propenyl)-2-demethyl-2-methoxy-24-methyl-hygrolidin Oxacyclohexadecane, hygrolidin deriv.; (-)-Bafilomycin A1; NSC 381866; [7R-[3Z, 5E, 7R*, 8S*, 9S*, 11E, 13E, 15S*, 16R*[1S*, 2R*, 3S*(2R*, 4R*, 5S*, 6R*)]]]-8-Hydroxy-16-[2-hydroxy-1-methyl-3-[tetrahydro-2, 4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3, 15-dimethoxy-5, 7, 9, 11-tetramethyl-oxacyclohexadeca-3, 5, 11, 13-tetraen-2-one. Grades: Highly Purified. CAS No. 88899-55-2. Pack Sizes: 100ug, 1mg. Molecular Formula: C35H58O9, Molecular Weight: 622.8. US Biological Life Sciences. | Worldwide |
| TAN-1323C | TAN-1323C is a concanamycin-group antibiotic produced by Streptomyces purpurascens. It showed remarkably potent angiostatic activity in the chick chorioallantoic membrane (CAM) assay. Synonyms: TAN 1323C. Molecular formula: C45H74O14. Mole weight: 839.1. | |
| TAN-1323D | TAN-1323D is a concanamycin-group antibiotic produced by Streptomyces purpurascens. It showed remarkably potent angiostatic activity in the chick chorioallantoic membrane (CAM) assay. Synonyms: TAN 1323D. Molecular formula: C43H66O13. Mole weight: 791. | |
| Viranamycin A | It is produced by the strain of Str. sp. CH 41. It can inhibit the growth of murine leukemia cell P388 with IC50 of 5.8 ng/mL, and it can also inhibit KB human multi-squamous cell carcinoma cells with IC50 of 6.4 ng/mL. Synonyms: Concanamycin A, 23-O-(3-carboxy-1-oxo-2-propenyl)-23-O-de[4-O-(aminocarbonyl)-2,6-dideoxy-b-D-arabino-hexopyranosyl]-25-de(1-propenyl)-25-methyl-. CAS No. 139595-03-2. Molecular formula: C41H64O13. Mole weight: 764.94. | |
| Viranamycin B | It is produced by the strain of Str. sp. CH 41. It can inhibit the growth of murine leukemia cell P388 with IC50 of 2.8 ng/mL, and it can also inhibit KB human multi-squamous cell carcinoma cells with IC50 of 1.9 ng/mL. Synonyms: Concanamycin A, 25-de(1-propenyl)-25-methyl-. CAS No. 139595-04-3. Molecular formula: C44H73NO14. Mole weight: 840.05. | |
| Virustomycin A | Virustomycin A is a 18-membered macrolide antibiotic originally isolated from Streptomyces sp. AM-2604. It is effective against infectious and plant pathogenic fungi. It is active against trichomonads and various RNA and DNA viruses. Synonyms: AM 2604A; Antibiotic AM 2604A; [2R-[2R*[1S*[2R*, 4R*, 5S*, 6R*(E)], 2R*, 3S*], 3S*, 4E, 6E, 9R*, 10S*, 11S*, 12R*, 13R*, 14E, 16Z]]-2-[3-(11-Ethyl-10, 12-dihydroxy-3, 17-dimethoxy-7, 9, 13, 15-tetramethyl-18-oxooxacyclooctadeca-4, 6, 14, 16-tetraen-2-yl)-2-hydroxy-1-methylbutyl]tetrahydro-2-hydroxy-5-methyl-6-(1-propenyl)-2H-pyran-4-yl Ester 4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-4-oxo-2-butenoic Acid; 23-O-De(4-O-aminocarbonyl-2,6-dideoxy-β-D-arabino-hexopyranosyl)-23-O-[4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-1,4-dioxo-2-butenyl]concanamycin A. Grades: ≥98%. CAS No. 84777-85-5. Molecular formula: C48H71NO14. Mole weight: 886.08. | |
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