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| Product | Description | |
|---|---|---|
| Conessine | Conessine, a steroidal alkaloid, is a potent and selective histamine H 3 receptor antagonist with K i s of 5.4, 6.0, 5.7 and 25 nM for human, dog, guinea pig, and rat H H 3 receptor, respectively. Anti-malarial activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 546-06-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107566. |  |
| Conessine | Conessine. Group: Biochemicals. Grades: Purified. CAS No. 546-06-5. Pack Sizes: 50mg. US Biological Life Sciences. |  Worldwide |
| Conessine | Conessine is a naturally occurring steroidal dibasic alkaloid with a rigid steroid-based skeleton. It is found in a number of plant species from the apocynaceae family. It is a selective, specific and potent histamine H3 receptor antagonist. It has high selectivity for both rat and human histamine H3 receptors. It has a poor rate of CNS clearance. It also binds to the human α2C4 adrenergic receptor. It has anti-malarial activity and displays in vitro antiplasmodial activity. It is used as a treatment for amoebic dysentery. It was developed by Abbott. Synonyms: Conessine; Conessinum; Konessin; Neriine; Roquessine; Wrightine; (3R, 3aR, 5aR, 5bR, 9R, 11aS, 11bR, 13aR)-N, N, 2, 3, 11a-pentamethyl-2, 3, 3a, 4, 5, 5a, 5b, 6, 8, 9, 10, 11, 11a, 11b, 12, 13-hexadecahydro-1H-naphtho[2', 1':4, 5]indeno[1, 7a-c]pyrrol-9-amine; (3β)-N,N-dimethyl-con-5-enin-3-amine; NSC 119994; Neriine; Roquessine; Wrightine; N,18-Dihydrotrimethylconkurchine; (+)-Conessine; N',18-Dihydro-N,N,N'-trimethylconkurchine; (3β)-N,N-Dimethylcon-5-enin-3-amine; 3β-(Dimethylamino)con-5-enine; N,N-Dimethyl-con-5-enin-3-amine. CAS No. 546-06-5. Molecular formula: C24H40N2. Mole weight: 356.59. |  |
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