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Cortistatin-14 Cortistatin-14 is a neuropeptide that shares structural similarities with somatostatin, working by binding to somatostatin receptors ( sst1 - sst5 ). Cortistatin-14 (TFA) has anticonvulsant, neuroprotective effects, and significant anti-inflammatory properties [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 186901-48-4. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P1932. MedChemExpress MCE
Cortistatin-14 trifluoroacetate salt Cortistatin-14 (TFA) is a neuropeptide which is structural similar to somatostatin-14 and it binds and exerts its function via the somatostatin receptors (sst1-sst5). Cortistatin-14 (TFA) shows anticonvulsive, neuroprotective effect and remarkable anti-inflammatory properties. Cortistatin-14 is an endogenous neuropeptide agonist of somatostatin receptors (IC50s = 0.5-18.2 nM for human SST1-SST5 receptors expressed in CCL39 cells). Grades: ≥95%. Molecular formula: C81H113N19O19S2·xCF3COOH. Mole weight: 1721.01. BOC Sciences 10
Cortistatin 14 (mouse, rat) Cortistatin-14 is an endogenous neuropeptide expressed in the cortex and hippocampus. Synonyms: Cortistatin-14; H-PRO-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-SER-SER-CYS-LYS-OH; CST-14; CST-14 (RAT). Grades: 98%. CAS No. 186901-48-4. Molecular formula: C81H113N19O19S2. Mole weight: 1721.01. BOC Sciences 8
Cortistatin-29 (rat) Cortistatin-29 is a neuropeptide that has structurally similarity to somatostatin-28. It is produced by cleavage of preprocortistatin to procortistatin, which is cleaved at dibasic amino acids to form cortistatin-29 and cortistatin-14 as well as other partial cleavage products. Synonyms: Pyr-Glu-Arg-Pro-Pro-Leu-Gln-Gln-Pro-Pro-His-Arg-Asp-Lys-Lys-Pro-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys-OH (Disulfide bridge: Cys17-Cys28); 5-oxo-L-prolyl-L-α-glutamyl-L-arginyl-L-prolyl-L-prolyl-L-leucyl-L-glutaminyl-L-glutaminyl-L-prolyl-L-prolyl-L-histidyl-L-arginyl-L-α-aspartyl-L-lysyl-L-lysyl-L-prolyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-seryl-L-seryl-L-cysteinyl-L-lysine, cyclic (17?28)-disulfide; L-pyroglutamyl-L-alpha-glutamyl-L-arginyl-L-prolyl-L-prolyl-L-leucyl-L-glutaminyl-L-glutaminyl-L-prolyl-L-prolyl-L-histidyl-L-arginyl-L-alpha-aspartyl-L-lysyl-L-lysyl-L-prolyl-D-cysteinyl-D-lysyl-L-asparagyl-L-phenylalanyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-D-phenylalanyl-D-seryl-L-seryl-L-cysteinyl-L-lysine (17->28)-disulfide. Grades: ≥95%. CAS No. 1815618-17-7. Molecular formula: C161H240N46O41S2. Mole weight: 3540.05. BOC Sciences 6

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