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CP 31398 dihydrochloride CP 31398 is a p53 stabilizer and could probably restrain the growth of small human tumor xenografts in vivo. CP 31398 is a prototype small molecule that stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53. Synonyms: CP31398 dihydrochloride; CP-31398 dihydrochloride; N'-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediamine dihydrochloride; 1,3-Propanediamine, N3-[2-[2-(4-methoxyphenyl)ethenyl]-4-quinazolinyl]-N1,N1-dimethyl-, hydrochloride (1:2); PZ 0115; N1-(2-(4-methoxystyryl)quinazolin-4-yl)-N3,N3-dimethylpropane-1,3-diamine dihydrochloride. Grades: ≥99% by HPLC. CAS No. 1217195-61-3. Molecular formula: C22H26N4O.2HCl. Mole weight: 435.39. BOC Sciences 9
CP 31398 dihydrochloride hydrate CP 31398 is a p53 stabilizer and could probably restrain the growth of small human tumor xenografts in vivo. CP 31398 is a prototype small molecule that stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53. Synonyms: 1,3-Propanediamine, N3-[2-[2-(4-methoxyphenyl)ethenyl]-4-quinazolinyl]-N1,N1-dimethyl-, hydrochloride, hydrate (1:2:1); CP31398 dihydrochloride hydrate; CP-31398 dihydrochloride hydrate; N'-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediamine dihydrochloride hydrate; N1-(2-(4-methoxystyryl)quinazolin-4-yl)-N3,N3-dimethylpropane-1,3-diamine dihydrochloride hydrate. Grades: ≥95%. CAS No. 1853109-76-8. Molecular formula: C22H26N4O.2HCl.H2O. Mole weight: 453.41. BOC Sciences 6

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