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CP-465022 CP-465022 is a potent, and selective noncompetitive AMPA receptor antagonist with anticonvulsant activity. CP-465022 is against Kainate-induced response with an IC 50 of 25 nM in rat cortical neurons. CP-465022 provides a new tool to investigate the role of AMPA receptors in physiological and pathophysiological processes [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 199655-36-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18663. MedChemExpress MCE
CP-465022 maleate CP-465022 is a selective, non-competitive AMPA antagonist that displays potent anticonvulsant activity. Synonyms: CP-465022 (maleate); 199656-46-7; cp-465022 maleate; (Z)-but-2-enedioic acid; 3-(2-chlorophenyl)-2-[(E)-2-[6-(diethylaminomethyl)pyridin-2-yl]ethenyl]-6-fluoroquinazolin-4-one; CP-392,110 (maleate); 3-(2-chlorophenyl)-2-[2-[6-[(diethylamino)methyl]-2-pyridinyl]ethenyl]-6-fluoro-4(3H)-quinazolinone-(2Z)-2-butenedioate; SCHEMBL8301393; CP465022(2Z)-2-butenedioate; ZHA65646; HY-18663A; AKOS037643494; CP 465022 (2Z)-2-butenedioate; AS-16611; CS-0013530. CAS No. 199656-46-7. Molecular formula: C26H24ClFN4O·C4H4O4. Mole weight: 579. BOC Sciences 10
CP 465022 CP 465022, with anticonvulsant activity, is a potent, brain penetrant, orally active and selective noncompetitive AMPA receptor antagonist (IC50 = 25 nM in rat cortical neurons). CP 465022 provides neuroprotective efficacy after cerebral ischemia on the basis of the activity in experimental ischemia models. Synonyms: 3-(2-chlorophenyl)-2-[2-[6-(diethylaminomethyl)pyridin-2-yl]ethenyl]-6-fluoroquinazolin-4-one; CP-465022; CP 465022; CP465022; UNII-4582JTR93Y. Grades: >99 %. CAS No. 199655-36-2. Molecular formula: C26H24ClFN4O. Mole weight: 499.41. BOC Sciences 10

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