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| Product | Description | |
|---|---|---|
| CPDA | CPDA, a 4-substituted 2-pyridin-2-ylamide, has potential to inhibit SHIP2 which was found to enhance insulin signaling through the Akt pathway in viro and greatly improved abnormal glucose metabolism in diabetic animals. Synonyms: N-[4-[(4-chlorophenyl)methoxy]pyridin-2-yl]-2-(2,6-difluorophenyl)acetamide CPDA CHEMBL2337808 SCHEMBL14156872 AKOS027447209 CS-4991 AK517293 HY-18685 N-[4-(4-Chlorobenzyloxy)-2-pyridyl]-2,6-difluorobenzeneacetamide N-(4-((4-Chlorobenzyl)oxy)pyridin-2-yl). CAS No. 1415834-63-7. Molecular formula: C20H15ClF2N2O2. Mole weight: 388.79. |  |
| CPDA | CPDA is a novel potent SH2 domain-containing inositol phosphatase 2 (SHIP2) inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 1415834-63-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18685. |  |
| SHIP2 Inhibitor II, CPDA | A cell-permeable aminopyridine acetamide based compound that acts as an inhibitor of SH2 domain-containing inositol 5-phosphatase 2 (SHIP2) that can overcome insulin resistance in 3T3-L1 adipocytes. Enhances insulin-stimulated Akt phosphorylation (Thr308) in TNFa-treated 3T3-L1 adipocytes (~10uM) and in primary cultured neurons from rat cerebral cortex. Improves glucose tolerance in db/db mice (~300mg/kg b.i.d) without affecting their fasting glucose levels. Also reduces the expression levels of glucose-6-phosphatase and phosphoenolpyruvate carboxykinase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??ClF?N?O?, Primary Target: SHIP2. US Biological Life Sciences. |  Worldwide |
| 4-[1-Chloro-2-(methylamino)ethyl]phenyl acetate hydrochloride | 4-[1-Chloro-2-(methylamino)ethyl]phenyl acetate hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Glucocorticoid Receptor Modulator, CpdA, 2-((4-Acetoxyphenyl)-2-chloro-N-methyl)ethylammonium chloride, 4-[1-CHLORO-2-(METHYLAMINO)ETHYL]PHENYL ACETATE HYDROCHLORIDE, 14593-25-0, PubChem19319, AKOS015888247, I01-10419. CAS No. 14593-25-0. Molecular formula: C11H15Cl2NO2. Mole weight: 264.15. Purity: 0.95. IUPACName: [4-[1-chloro-2-(methylamino)ethyl]phenyl] acetate;hydrochloride. Product ID: ACM14593250. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 4-[1-Chloro-2-(methylamino)ethyl]phenyl Acetate Hydrochloride | CpdA is a non-steroidal selective glucocorticoid receptor modulator. It can inhibit the dimerization of glucocorticoid receptor, which prevents transcription of gene targets such as NF-κB and subsequent cytokines through transrepression. Synonyms: acetic acid [4-[1-chloro-2-(methylamino)ethyl]phenyl] ester;hydrochloride; [4-[1-chloro-2-(methylamino)ethyl]phenyl] acetate;hydrochloride. Grades: ≥ 98 %. CAS No. 14593-25-0. Molecular formula: C11H15Cl2NO2. Mole weight: 264.15. | |
| GPR120-IN-1 | GPR120-IN-1, a cell-permeable azaspiroundecanyl acetic acid compound, is an orally available, selective agonist of GPR120 (EC50 = ~0.35 μM) that demonstrates potent selectivity over another lipid-sensing G-protein, GPR40 (FFAR1). Synonyms: 2-[3-[2-chloro-5-(trifluoromethoxy)phenyl]-3-azaspiro[5.5]undecan-9-yl]acetic acid; GPR120 Compound A; MDK77754; MDK-77754; MDK 77754; GPR120 cpdA. CAS No. 1599477-75-4. Molecular formula: C19H23ClF3NO3. Mole weight: 405.84. | |
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